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Volumn 118, Issue 26, 2011, Pages 6724-6726

Predicting cytokine storms: It's about density

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CYTOKINE; TGN 1412;

EID: 84455172814     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-10-382598     Document Type: Note
Times cited : (12)

References (11)
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    • Römer P, Berr S, Avota E, et al. Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412. Blood. 2011;118(26):6772-6782.
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  • 3
    • 37749032491 scopus 로고    scopus 로고
    • "Cytokine storm" in the phase 1 trial of monoclonal antibody TGN1412: Better understanding the causes to improve preclinical testing of immunotherapeutics
    • Stebbings R, Findlay L, Edwards C, et al. "Cytokine storm" in the phase 1 trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics. J Immunol. 2007;179(5):3325-3331.
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  • 4
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    • Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412
    • Findlay L, Eastwood D, Stebbings R, et al. Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412. J Immunol Methods. 2010;352(1-2):1-12.
    • (2010) J Immunol Methods , vol.352 , Issue.1-2 , pp. 1-12
    • Findlay, L.1    Eastwood, D.2    Stebbings, R.3
  • 5
    • 84864279250 scopus 로고    scopus 로고
    • Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice
    • Gogishvili T, Langenhorst D, Luhder F, et al. Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice. PLoS One. 2009;4(2):e4643.
    • (2009) PLoS One , vol.4 , Issue.2
    • Gogishvili, T.1    Langenhorst, D.2    Luhder, F.3
  • 6
    • 55549108671 scopus 로고    scopus 로고
    • Toward experimental assessment of receptor occupancy: TGN1412 revisited
    • Waibler Z, Sender L, Kamp C, et al. Toward experimental assessment of receptor occupancy: TGN1412 revisited. J Allergy Clin Immunol. 2008;122(5):890-892.
    • (2008) J Allergy Clin Immunol , vol.122 , Issue.5 , pp. 890-892
    • Waibler, Z.1    Sender, L.2    Kamp, C.3
  • 7
    • 77956304908 scopus 로고    scopus 로고
    • Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells
    • Eastwood D, Findlay L, Poole S, et al. Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells. Br J Pharmacol. 2010;161(3):512-526.
    • (2010) Br J Pharmacol , vol.161 , Issue.3 , pp. 512-526
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  • 8
    • 79960131812 scopus 로고    scopus 로고
    • Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression
    • Paiardini M, Cervasi B, Reyes-Aviles E, et al. Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression. Nat Med. 2011;17(7):830-836.
    • (2011) Nat Med , vol.17 , Issue.7 , pp. 830-836
    • Paiardini, M.1    Cervasi, B.2    Reyes-Aviles, E.3
  • 9
    • 0017186979 scopus 로고
    • Polyclonal activation of bone-marrow-derived lymphocytes from human peripheral blood measured by a direct plaque-forming cell assay
    • Fauci AS, Pratt KR. Polyclonal activation of bone-marrow-derived lymphocytes from human peripheral blood measured by a direct plaque-forming cell assay. Proc Natl Acad Sci U S A. 1976;73(1):3676-3679.
    • (1976) Proc Natl Acad Sci U S A , vol.73 , Issue.1 , pp. 3676-3679
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  • 10
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    • Accelerated production of antigen-specific T-cells for pre-clinical and clinical applications using Gas-permeable Rapid Expansion cultureware (G-Rex)
    • Vera JF, Brenner LJ, Gerdemann U, et al. Accelerated production of antigen-specific T-cells for pre-clinical and clinical applications using Gas-permeable Rapid Expansion cultureware (G-Rex). J Immunother. 2010;33(3):305-315.
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  • 11
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    • (1996) Journal of Experimental Medicine , vol.183 , Issue.6 , pp. 2675-2680
    • Saha, B.1    Harlan, D.M.2    Lee, K.P.3    June, C.H.4    Abe, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.