Research/review: Structure and linkage disequilibrium analysis of adamantane resistant mutations in influenza virus M2 proton channel

Current Drug Metabolism

Volumn 15, Issue 5, 2014, Pages 526-534

  Yu, Yao ^a,b   Li, Xuan ^a,b   Hao, Pei ^b,c   Wang, Jing Fang ^b,d,f   Chou, Kuo Chen ^e,f  

^a INSTITUTE OF PLANT PHYSIOLOGY AND ECOLOGY   (China)

^b SHANGHAI CENTER FOR BIOINFORMATION TECHNOLOGY   (China)

^c INSTITUTE PASTEUR OF SHANGHAI   (China)

^d Chinese National Human Genome Center at Shanghai   (China)

^e KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^f GORDON LIFE SCIENCE INSTITUTE   (United States)

Author keywords

Allosteric mechanism; Drug resistance; Influenza A virus; M2 proton channel; Proton transition

Indexed keywords

PROTEIN M2; RIMANTADINE; ADAMANTANE; ANTIVIRUS AGENT; M2 PROTEIN, INFLUENZA A VIRUS; MATRIX PROTEIN;

2009 H1N1 INFLUENZA; ALLOSTERISM; ANTIVIRAL RESISTANCE; BIRD; CARBOXY TERMINAL SEQUENCE; GENE LINKAGE DISEQUILIBRIUM; HUMAN; INFLUENZA VIRUS; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; INFLUENZA VIRUS A H7N2; INFLUENZA VIRUS A H9N2; LIPID BILAYER; MOLECULAR DYNAMICS; NONHUMAN; REVIEW; SEQUENCE HOMOLOGY; SWINE; VIRUS MUTATION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; INFLUENZA A VIRUS (H1N1); MULTIDRUG RESISTANCE; MUTATION; PROTEIN CONFORMATION;

ADAMANTANE; ANIMALS; ANTIVIRAL AGENTS; DRUG RESISTANCE, MULTIPLE, VIRAL; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; LINKAGE DISEQUILIBRIUM; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN CONFORMATION; VIRAL MATRIX PROTEINS;

EID: 84925719038     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/1389200215666140605130406     Document Type: Review

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