Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase

Analytical Biochemistry

Volumn 337, Issue 2, 2005, Pages 262-270

  Du, Qishi ^a,d   Wang, Shuqing ^a   Wei, Dongqing ^a,d,e   Sirois, Suzanne ^b,c,d,e   Chou, Kuo Chen ^a,c  

^a TIANJIN NORMAL UNIVERSITY   (China)

^b Gina Cody School of Engineering and Computer Science   (Canada)

^c UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^d MONTREAL GENERAL HOSPITAL   (Canada)

^e GORDON LIFE SCIENCE INSTITUTE   (United States)

Author keywords

"Distorted key" theory; Drug design; Inhibitor; SARS; SARS CoV Mpro

Indexed keywords

CATALYSIS; CHEMICAL MODIFICATION; COBALT ALLOYS; PEPTIDES; QUANTUM CHEMISTRY; QUANTUM THEORY; VIRUSES;

DISTORTED-KEY THEORIES; DRUG DESIGN; INHIBITOR; SARS; SARS COV M^PRO;

DISEASES;

ANTIVIRUS AGENT; CARBONYL DERIVATIVE; IMIDAZOLE; MAIN PROTEINASE; OCTAPEPTIDE; PROTEIN INHIBITOR; PROTEINASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL MODIFICATION; DRUG DESIGN; DRUG STRUCTURE; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME STRUCTURE; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; QUANTUM CHEMISTRY; SARS CORONAVIRUS; SEQUENCE ANALYSIS; SIMULATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THEORETICAL STUDY;

CORONAVIRUS; SARS CORONAVIRUS;

EID: 13244290092     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.10.003     Document Type: Article

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