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Volumn 22, Issue 4, 2015, Pages 416-426

Hepatitis B virus (HBV) variants fluctuate in paired plasma and peripheral blood mononuclear cells among patient cohorts during different chronic hepatitis B (CHB) disease phases

Author keywords

chronic hepatitis B; clonal sequencing; genotype; lymphoid; quasispecies

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

EID: 84925607143     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12308     Document Type: Article
Times cited : (35)

References (60)
  • 1
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B virus infection-natural history and clinical consequences
    • Ganem D, Prince A,. Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 2004; 350 (11): 1118-1129.
    • (2004) N Engl J Med , vol.350 , Issue.11 , pp. 1118-1129
    • Ganem, D.1    Prince, A.2
  • 2
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • Chisari FV, Ferrari C,. Hepatitis B virus immunopathogenesis. Annu Rev Immunol 1995; 13: 29-60.
    • (1995) Annu Rev Immunol , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 3
    • 79957481330 scopus 로고    scopus 로고
    • Virological breakthrough and resistance in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice
    • Hongthanakorn C, Chotiyaputta W, Oberhelman K, et al,. Virological breakthrough and resistance in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice. Hepatology 2011; 53 (6): 1854-1863.
    • (2011) Hepatology , vol.53 , Issue.6 , pp. 1854-1863
    • Hongthanakorn, C.1    Chotiyaputta, W.2    Oberhelman, K.3
  • 4
    • 9144223295 scopus 로고    scopus 로고
    • Genetic diversity of hepatitis B virus strains derived worldwide: Genotypes, subgenotypes, and HBsAg subtypes
    • Norder H, Courouce AM, Coursaget P, et al,. Genetic diversity of hepatitis B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes. Intervirology 2004; 47 (6): 289-309.
    • (2004) Intervirology , vol.47 , Issue.6 , pp. 289-309
    • Norder, H.1    Courouce, A.M.2    Coursaget, P.3
  • 5
    • 83455179343 scopus 로고    scopus 로고
    • HBV genotypes: Relevance to natural history, pathogenesis and treatment of chronic hepatitis B
    • Kim BK, Revill PA, Ahn SH,. HBV genotypes: relevance to natural history, pathogenesis and treatment of chronic hepatitis B. Antivir Ther 2011; 16 (8): 1169-1186.
    • (2011) Antivir Ther , vol.16 , Issue.8 , pp. 1169-1186
    • Kim, B.K.1    Revill, P.A.2    Ahn, S.H.3
  • 6
    • 33745619248 scopus 로고    scopus 로고
    • Hepatitis B virus mutations associated with antiviral therapy
    • Bartholomeusz A, Locarnini S,. Hepatitis B virus mutations associated with antiviral therapy. J Med Virol 2006; 78 (Suppl. 1): S52-S55.
    • (2006) J Med Virol , vol.78 , pp. S52-S55
    • Bartholomeusz, A.1    Locarnini, S.2
  • 7
    • 41149084629 scopus 로고    scopus 로고
    • Hepatitis B virus escape mutants induced by antiviral therapy
    • Sheldon J, Soriano V,. Hepatitis B virus escape mutants induced by antiviral therapy. J Antimicrob Chemother 2008; 61 (4): 766-768.
    • (2008) J Antimicrob Chemother , vol.61 , Issue.4 , pp. 766-768
    • Sheldon, J.1    Soriano, V.2
  • 8
    • 33750332094 scopus 로고    scopus 로고
    • Molecular evolution of hepatitis B virus over 25 years
    • Osiowy C, Giles E, Tanaka Y, Mizokami M, Minuk GY,. Molecular evolution of hepatitis B virus over 25 years. J Virol 2006; 80 (21): 10307-10314.
    • (2006) J Virol , vol.80 , Issue.21 , pp. 10307-10314
    • Osiowy, C.1    Giles, E.2    Tanaka, Y.3    Mizokami, M.4    Minuk, G.Y.5
  • 9
    • 84880783663 scopus 로고    scopus 로고
    • Impact of genetic heterogeneity in polymerase of hepatitis B virus on dynamics of viral load and hepatitis B progression
    • Huang CJ, Wu CF, Lan CY, et al,. Impact of genetic heterogeneity in polymerase of hepatitis B virus on dynamics of viral load and hepatitis B progression. PLoS ONE 2013; 8 (7): e70169.
    • (2013) PLoS ONE , vol.8 , Issue.7 , pp. e70169
    • Huang, C.J.1    Wu, C.F.2    Lan, C.Y.3
  • 10
    • 84872407158 scopus 로고    scopus 로고
    • Increased viral quasispecies evolution in HBeAg seroconverter patients treated with oral nucleoside therapy
    • Cheng Y, Guindon S, Rodrigo A, Lim SG,. Increased viral quasispecies evolution in HBeAg seroconverter patients treated with oral nucleoside therapy. J Hepatol 2013; 58 (2): 217-224.
    • (2013) J Hepatol , vol.58 , Issue.2 , pp. 217-224
    • Cheng, Y.1    Guindon, S.2    Rodrigo, A.3    Lim, S.G.4
  • 11
    • 84984586038 scopus 로고    scopus 로고
    • Distinct hepatitis B virus dynamics in the immunotolerant and early immunoclearance phases
    • Wang HY, Chien MH, Huang HP, et al,. Distinct hepatitis B virus dynamics in the immunotolerant and early immunoclearance phases. J Virol 2010; 84 (7): 3454-3463.
    • (2010) J Virol , vol.84 , Issue.7 , pp. 3454-3463
    • Wang, H.Y.1    Chien, M.H.2    Huang, H.P.3
  • 12
    • 84878198429 scopus 로고    scopus 로고
    • Distinct quasispecies characteristics and positive selection within precore/core gene in hepatitis B virus HBV associated acute-on-chronic liver failure
    • Chen L, Zheng CX, Lin MH, et al,. Distinct quasispecies characteristics and positive selection within precore/core gene in hepatitis B virus HBV associated acute-on-chronic liver failure. J Gastroenterol Hepatol 2013; 28 (6): 1040-1046.
    • (2013) J Gastroenterol Hepatol , vol.28 , Issue.6 , pp. 1040-1046
    • Chen, L.1    Zheng, C.X.2    Lin, M.H.3
  • 13
    • 34548513797 scopus 로고    scopus 로고
    • Viral quasi-species evolution during hepatitis Be antigen seroconversion
    • Lim SG, Cheng Y, Guindon S, et al,. Viral quasi-species evolution during hepatitis Be antigen seroconversion. Gastroenterology 2007; 133 (3): 951-958.
    • (2007) Gastroenterology , vol.133 , Issue.3 , pp. 951-958
    • Lim, S.G.1    Cheng, Y.2    Guindon, S.3
  • 14
    • 64549125990 scopus 로고    scopus 로고
    • Early changes of hepatitis B virus quasispecies during lamivudine treatment and the correlation with antiviral efficacy
    • Chen L, Zhang Q, Yu DM, Wan MB, Zhang XX,. Early changes of hepatitis B virus quasispecies during lamivudine treatment and the correlation with antiviral efficacy. J Hepatol 2009; 50 (5): 895-905.
    • (2009) J Hepatol , vol.50 , Issue.5 , pp. 895-905
    • Chen, L.1    Zhang, Q.2    Yu, D.M.3    Wan, M.B.4    Zhang, X.X.5
  • 15
    • 80051547019 scopus 로고    scopus 로고
    • Evolutionary patterns of hepatitis B virus quasispecies under different selective pressures: Correlation with antiviral efficacy
    • Liu F, Chen L, Yu DM, et al,. Evolutionary patterns of hepatitis B virus quasispecies under different selective pressures: correlation with antiviral efficacy. Gut 2011; 60 (9): 1269-1277.
    • (2011) Gut , vol.60 , Issue.9 , pp. 1269-1277
    • Liu, F.1    Chen, L.2    Yu, D.M.3
  • 16
    • 54549121531 scopus 로고    scopus 로고
    • Biological and clinical implications of HBV infection in peripheral blood mononuclear cells
    • Pontisso P, Vidalino L, Quarta S, Gatta A,. Biological and clinical implications of HBV infection in peripheral blood mononuclear cells. Autoimmun Rev 2008; 8 (1): 13-17.
    • (2008) Autoimmun Rev , vol.8 , Issue.1 , pp. 13-17
    • Pontisso, P.1    Vidalino, L.2    Quarta, S.3    Gatta, A.4
  • 17
    • 0842304530 scopus 로고    scopus 로고
    • Low doses of hepadnavirus induce infection of the lymphatic system that does not engage the liver
    • Michalak TI, Mulrooney PM, Coffin CS,. Low doses of hepadnavirus induce infection of the lymphatic system that does not engage the liver. J Virol 2004; 78 (4): 1730-1738.
    • (2004) J Virol , vol.78 , Issue.4 , pp. 1730-1738
    • Michalak, T.I.1    Mulrooney, P.M.2    Coffin, C.S.3
  • 18
    • 0032738688 scopus 로고    scopus 로고
    • Persistence of infectious hepadnavirus in the offspring of woodchuck mothers recovered from viral hepatitis
    • Coffin CS, Michalak TI,. Persistence of infectious hepadnavirus in the offspring of woodchuck mothers recovered from viral hepatitis. J Clin Invest 1999; 104 (2): 203-212.
    • (1999) J Clin Invest , vol.104 , Issue.2 , pp. 203-212
    • Coffin, C.S.1    Michalak, T.I.2
  • 19
    • 70349298395 scopus 로고    scopus 로고
    • Genetic characterization of hepatitis B virus in peripheral blood leukocytes: Evidence for selection and compartmentalization of viral variants with the immune escape G145R mutation
    • Datta S, Panigrahi R, Biswas A, et al,. Genetic characterization of hepatitis B virus in peripheral blood leukocytes: evidence for selection and compartmentalization of viral variants with the immune escape G145R mutation. J Virol 2009; 83 (19): 9983-9992.
    • (2009) J Virol , vol.83 , Issue.19 , pp. 9983-9992
    • Datta, S.1    Panigrahi, R.2    Biswas, A.3
  • 20
    • 79960793477 scopus 로고    scopus 로고
    • Hepatitis B virus quasispecies in hepatic and extrahepatic viral reservoirs in liver transplant recipients on prophylactic therapy
    • Coffin CS, Mulrooney-Cousins PM, van Marle G, Roberts JP, Michalak TI, Terrault NA,. Hepatitis B virus quasispecies in hepatic and extrahepatic viral reservoirs in liver transplant recipients on prophylactic therapy. Liver Transpl 2011; 17 (8): 955-962.
    • (2011) Liver Transpl , vol.17 , Issue.8 , pp. 955-962
    • Coffin, C.S.1    Mulrooney-Cousins, P.M.2    Van Marle, G.3    Roberts, J.P.4    Michalak, T.I.5    Terrault, N.A.6
  • 21
    • 79955386249 scopus 로고    scopus 로고
    • Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy
    • Coffin CS, Mulrooney-Cousins PM, Peters MG, et al,. Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy. J Viral Hepat 2011; 18 (6): 415-423.
    • (2011) J Viral Hepat , vol.18 , Issue.6 , pp. 415-423
    • Coffin, C.S.1    Mulrooney-Cousins, P.M.2    Peters, M.G.3
  • 22
    • 84883753119 scopus 로고    scopus 로고
    • Characterization of hepatitis B virus genotypes and quantitative hepatitis B surface antigen titres in North American tertiary referral liver centres
    • Congly SE, Wong P, Al-Busafi SA, et al,. Characterization of hepatitis B virus genotypes and quantitative hepatitis B surface antigen titres in North American tertiary referral liver centres. Liver Int 2013; 33 (9): 1363-1369.
    • (2013) Liver Int , vol.33 , Issue.9 , pp. 1363-1369
    • Congly, S.E.1    Wong, P.2    Al-Busafi, S.A.3
  • 23
    • 79952677618 scopus 로고    scopus 로고
    • Distinct geographical and demographic distribution of hepatitis B virus genotypes in the Canadian Arctic as revealed through an extensive molecular epidemiological survey
    • Osiowy C, Larke B, Giles E,. Distinct geographical and demographic distribution of hepatitis B virus genotypes in the Canadian Arctic as revealed through an extensive molecular epidemiological survey. J Viral Hepat 2011; 18 (4): e11-e19.
    • (2011) J Viral Hepat , vol.18 , Issue.4 , pp. e11-e19
    • Osiowy, C.1    Larke, B.2    Giles, E.3
  • 24
    • 0029082116 scopus 로고
    • A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients
    • Gunther S, Li BC, Miska S, Kruger DH, Meisel H, Will H,. A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol 1995; 69 (9): 5437-5444.
    • (1995) J Virol , vol.69 , Issue.9 , pp. 5437-5444
    • Gunther, S.1    Li, B.C.2    Miska, S.3    Kruger, D.H.4    Meisel, H.5    Will, H.6
  • 25
    • 33847020352 scopus 로고    scopus 로고
    • Selecting a genetic region for molecular analysis of hepatitis B virus transmission
    • author reply 8
    • Datta S, Banerjee A, Chandra PK, Chakravarty R,. Selecting a genetic region for molecular analysis of hepatitis B virus transmission. J Clin Microbiol 2007; 45 (2): 687; author reply 8.
    • (2007) J Clin Microbiol , vol.45 , Issue.2 , pp. 687
    • Datta, S.1    Banerjee, A.2    Chandra, P.K.3    Chakravarty, R.4
  • 26
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S,. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011; 28 (10): 2731-2739.
    • (2011) Mol Biol Evol , vol.28 , Issue.10 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 27
    • 70350095437 scopus 로고    scopus 로고
    • Hepatitis B virus resistance to nucleos(t)ide analogues
    • e1-2
    • Zoulim F, Locarnini S,. Hepatitis B virus resistance to nucleos(t)ide analogues. Gastroenterology 2009; 137 (5): 1593-1608.e1-2.
    • (2009) Gastroenterology , vol.137 , Issue.5 , pp. 1593-1608
    • Zoulim, F.1    Locarnini, S.2
  • 28
    • 34247222010 scopus 로고    scopus 로고
    • Drug targets and molecular mechanisms of drug resistance in chronic hepatitis B
    • Ghany M, Liang TJ,. Drug targets and molecular mechanisms of drug resistance in chronic hepatitis B. Gastroenterology 2007; 132 (4): 1574-1585.
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1574-1585
    • Ghany, M.1    Liang, T.J.2
  • 29
    • 84871884647 scopus 로고    scopus 로고
    • The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    • Qin B, Budeus B, Cao L, et al,. The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir. Antiviral Res 2013; 97 (2): 93-100.
    • (2013) Antiviral Res , vol.97 , Issue.2 , pp. 93-100
    • Qin, B.1    Budeus, B.2    Cao, L.3
  • 30
    • 0036038911 scopus 로고    scopus 로고
    • Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene
    • Torresi J, Earnest-Silveira L, Civitico G, et al,. Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene. Virology 2002; 299 (1): 88-99.
    • (2002) Virology , vol.299 , Issue.1 , pp. 88-99
    • Torresi, J.1    Earnest-Silveira, L.2    Civitico, G.3
  • 31
    • 0033986638 scopus 로고    scopus 로고
    • Effect of variation in the common "a" determinant on the antigenicity of hepatitis B surface antigen
    • Seddigh-Tonekaboni S, Waters JA, Jeffers S, et al,. Effect of variation in the common "a" determinant on the antigenicity of hepatitis B surface antigen. J Med Virol 2000; 60 (2): 113-121.
    • (2000) J Med Virol , vol.60 , Issue.2 , pp. 113-121
    • Seddigh-Tonekaboni, S.1    Waters, J.A.2    Jeffers, S.3
  • 32
    • 0034767666 scopus 로고    scopus 로고
    • Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers
    • Hou J, Wang Z, Cheng J, et al,. Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers. Hepatology 2001; 34 (5): 1027-1034.
    • (2001) Hepatology , vol.34 , Issue.5 , pp. 1027-1034
    • Hou, J.1    Wang, Z.2    Cheng, J.3
  • 33
    • 33847694379 scopus 로고    scopus 로고
    • Molecular and functional analysis of occult hepatitis B virus isolates from patients with hepatocellular carcinoma
    • Pollicino T, Raffa G, Costantino L, et al,. Molecular and functional analysis of occult hepatitis B virus isolates from patients with hepatocellular carcinoma. Hepatology 2007; 45 (2): 277-285.
    • (2007) Hepatology , vol.45 , Issue.2 , pp. 277-285
    • Pollicino, T.1    Raffa, G.2    Costantino, L.3
  • 34
    • 46049104879 scopus 로고    scopus 로고
    • Multiple surface antigen mutations in five blood donors with occult hepatitis B virus infection
    • Zaaijer HL, Torres P, Ontanon A, et al,. Multiple surface antigen mutations in five blood donors with occult hepatitis B virus infection. J Med Virol 2008; 80 (8): 1344-1349.
    • (2008) J Med Virol , vol.80 , Issue.8 , pp. 1344-1349
    • Zaaijer, H.L.1    Torres, P.2    Ontanon, A.3
  • 35
    • 33644769201 scopus 로고    scopus 로고
    • Coexistence of hepatitis B surface antigen (HBs Ag) and anti-HBs antibodies in chronic hepatitis B virus carriers: Influence of "a" determinant variants
    • Lada O, Benhamou Y, Poynard T, Thibault V,. Coexistence of hepatitis B surface antigen (HBs Ag) and anti-HBs antibodies in chronic hepatitis B virus carriers: influence of "a" determinant variants. J Virol 2006; 80 (6): 2968-2975.
    • (2006) J Virol , vol.80 , Issue.6 , pp. 2968-2975
    • Lada, O.1    Benhamou, Y.2    Poynard, T.3    Thibault, V.4
  • 36
    • 83555163877 scopus 로고    scopus 로고
    • Nucleotide change of codon 182 in the surface gene of hepatitis B virus genotype C leading to truncated surface protein is associated with progression of liver diseases
    • Lee SA, Kim K, Kim H, Kim BJ,. Nucleotide change of codon 182 in the surface gene of hepatitis B virus genotype C leading to truncated surface protein is associated with progression of liver diseases. J Hepatol 2012; 56 (1): 63-69.
    • (2012) J Hepatol , vol.56 , Issue.1 , pp. 63-69
    • Lee, S.A.1    Kim, K.2    Kim, H.3    Kim, B.J.4
  • 37
    • 0042941863 scopus 로고    scopus 로고
    • Fatal hepatitis B virus reactivation by an escape mutant following rituximab therapy
    • Westhoff TH, Jochimsen F, Schmittel A, et al,. Fatal hepatitis B virus reactivation by an escape mutant following rituximab therapy. Blood 2003; 102 (5): 1930.
    • (2003) Blood , vol.102 , Issue.5 , pp. 1930
    • Westhoff, T.H.1    Jochimsen, F.2    Schmittel, A.3
  • 38
    • 0031047631 scopus 로고    scopus 로고
    • Evidence for selection of hepatitis B mutants after liver transplantation through peripheral blood mononuclear cell infection
    • Brind A, Jiang J, Samuel D, et al,. Evidence for selection of hepatitis B mutants after liver transplantation through peripheral blood mononuclear cell infection. J Hepatol 1997; 26 (2): 228-235.
    • (1997) J Hepatol , vol.26 , Issue.2 , pp. 228-235
    • Brind, A.1    Jiang, J.2    Samuel, D.3
  • 39
    • 84889084256 scopus 로고    scopus 로고
    • Role of peripheral blood mononuclear cell transportation from mother to baby in HBV intrauterine infection
    • Shao Q, Zhao X, Yao Li MD,. Role of peripheral blood mononuclear cell transportation from mother to baby in HBV intrauterine infection. Arch Gynecol Obstet 2013; 288 (6): 1257-1261.
    • (2013) Arch Gynecol Obstet , vol.288 , Issue.6 , pp. 1257-1261
    • Shao, Q.1    Zhao, X.2    Yao Li, M.D.3
  • 40
    • 0036891657 scopus 로고    scopus 로고
    • Presence of hepatitis B surface antigen mutant G145R DNA in the peripheral blood leukocytes of the family members of an asymptomatic carrier and evidence of its horizontal transmission
    • Chakravarty R, Neogi M, Roychowdhury S, Panda CK,. Presence of hepatitis B surface antigen mutant G145R DNA in the peripheral blood leukocytes of the family members of an asymptomatic carrier and evidence of its horizontal transmission. Virus Res 2002; 90 (1-2): 133-141.
    • (2002) Virus Res , vol.90 , Issue.12 , pp. 133-141
    • Chakravarty, R.1    Neogi, M.2    Roychowdhury, S.3    Panda, C.K.4
  • 41
    • 84870977400 scopus 로고    scopus 로고
    • A novel stop codon mutation within the hepatitis B surface gene is detected in the liver but not in the peripheral blood mononuclear cells of HIV-infected individuals with occult HBV infection
    • Cassini R, De Mitri MS, Gibellini D, et al,. A novel stop codon mutation within the hepatitis B surface gene is detected in the liver but not in the peripheral blood mononuclear cells of HIV-infected individuals with occult HBV infection. J Viral Hepat 2013; 20 (1): 42-49.
    • (2013) J Viral Hepat , vol.20 , Issue.1 , pp. 42-49
    • Cassini, R.1    De Mitri, M.S.2    Gibellini, D.3
  • 42
    • 73849109355 scopus 로고    scopus 로고
    • Virological pattern of hepatitis B infection in an HIV-positive man with fatal fulminant hepatitis B: A case report
    • Bagaglio S, Albarello L, Biswas P, Uberti-Foppa C, Fortis C, Morsica G,. Virological pattern of hepatitis B infection in an HIV-positive man with fatal fulminant hepatitis B: a case report. J Med Case Rep 2009; 3: 110.
    • (2009) J Med Case Rep , vol.3 , pp. 110
    • Bagaglio, S.1    Albarello, L.2    Biswas, P.3    Uberti-Foppa, C.4    Fortis, C.5    Morsica, G.6
  • 43
    • 0032978313 scopus 로고    scopus 로고
    • Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis
    • Michalak TI, Pardoe IU, Coffin CS, et al,. Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis. Hepatology 1999; 29 (3): 928-938.
    • (1999) Hepatology , vol.29 , Issue.3 , pp. 928-938
    • Michalak, T.I.1    Pardoe, I.U.2    Coffin, C.S.3
  • 44
    • 21644448547 scopus 로고    scopus 로고
    • Compartmentalization of hepatitis C virus quasispecies in blood mononuclear cells of patients with mixed cryoglobulinemic syndrome
    • Zehender G, De Maddalena C, Bernini F, et al,. Compartmentalization of hepatitis C virus quasispecies in blood mononuclear cells of patients with mixed cryoglobulinemic syndrome. J Virol 2005; 79 (14): 9145-9156.
    • (2005) J Virol , vol.79 , Issue.14 , pp. 9145-9156
    • Zehender, G.1    De Maddalena, C.2    Bernini, F.3
  • 46
    • 77956481810 scopus 로고    scopus 로고
    • Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infection
    • van Marle G, Church DL, Nunweiler KD, Cannon K, Wainberg MA, Gill MJ,. Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infection. Retrovirology 2010; 7: 74.
    • (2010) Retrovirology , vol.7 , pp. 74
    • Van Marle, G.1    Church, D.L.2    Nunweiler, K.D.3    Cannon, K.4    Wainberg, M.A.5    Gill, M.J.6
  • 47
    • 0037455578 scopus 로고    scopus 로고
    • Differential cellular distribution of HIV-1 drug resistance in vivo: Evidence for infection of CD8 + T cells during HAART
    • Potter SJ, Dwyer DE, Saksena NK,. Differential cellular distribution of HIV-1 drug resistance in vivo: evidence for infection of CD8 + T cells during HAART. Virology 2003; 305 (2): 339-352.
    • (2003) Virology , vol.305 , Issue.2 , pp. 339-352
    • Potter, S.J.1    Dwyer, D.E.2    Saksena, N.K.3
  • 48
    • 84901775489 scopus 로고    scopus 로고
    • Evidence of distinct populations of hepatitis C virus in the liver and plasma of patients co-infected with HIV and HCV
    • Blackard JT, Ma G, Sengupta S, et al,. Evidence of distinct populations of hepatitis C virus in the liver and plasma of patients co-infected with HIV and HCV. J Med Virol 2014; 86 (8): 1332-1341.
    • (2014) J Med Virol , vol.86 , Issue.8 , pp. 1332-1341
    • Blackard, J.T.1    Ma, G.2    Sengupta, S.3
  • 49
    • 84875225473 scopus 로고    scopus 로고
    • Dynamics of hepatitis B virus quasispecies heterogeneity and virologic response in patients receiving low-to-moderate genetic barrier nucleoside analogs
    • Peveling-Oberhag J, Herrmann E, Kronenberger B, et al,. Dynamics of hepatitis B virus quasispecies heterogeneity and virologic response in patients receiving low-to-moderate genetic barrier nucleoside analogs. J Viral Hepat 2013; 20 (4): 234-239.
    • (2013) J Viral Hepat , vol.20 , Issue.4 , pp. 234-239
    • Peveling-Oberhag, J.1    Herrmann, E.2    Kronenberger, B.3
  • 50
    • 84879394570 scopus 로고    scopus 로고
    • Quasispecies and pre-existing drug-resistant mutations of hepatitis B virus in patients with chronic hepatitis B
    • Kim do Y, Chang HY, Lim SM, et al,. Quasispecies and pre-existing drug-resistant mutations of hepatitis B virus in patients with chronic hepatitis B. Gut Liver 2013; 7 (3): 329-334.
    • (2013) Gut Liver , vol.7 , Issue.3 , pp. 329-334
    • Kim Do, Y.1    Chang, H.Y.2    Lim, S.M.3
  • 51
    • 84883242697 scopus 로고    scopus 로고
    • Characterization of the dynamics of hepatitis B virus resistance to adefovir by ultra-deep pyrosequencing
    • Rodriguez C, Chevaliez S, Bensadoun P, Pawlotsky JM,. Characterization of the dynamics of hepatitis B virus resistance to adefovir by ultra-deep pyrosequencing. Hepatology 2013; 58 (3): 890-901.
    • (2013) Hepatology , vol.58 , Issue.3 , pp. 890-901
    • Rodriguez, C.1    Chevaliez, S.2    Bensadoun, P.3    Pawlotsky, J.M.4
  • 52
    • 77955485392 scopus 로고    scopus 로고
    • Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B
    • Reijnders JG, Perquin MJ, Zhang N, Hansen BE, Janssen HL,. Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B. Gastroenterology 2010; 139 (2): 491-498.
    • (2010) Gastroenterology , vol.139 , Issue.2 , pp. 491-498
    • Reijnders, J.G.1    Perquin, M.J.2    Zhang, N.3    Hansen, B.E.4    Janssen, H.L.5
  • 53
    • 0032967659 scopus 로고    scopus 로고
    • Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma
    • Oon CJ, Chen WN, Zhao Y, Teng SW, Leong AL,. Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma. Cancer Lett 1999; 136 (1): 95-99.
    • (1999) Cancer Lett , vol.136 , Issue.1 , pp. 95-99
    • Oon, C.J.1    Chen, W.N.2    Zhao, Y.3    Teng, S.W.4    Leong, A.L.5
  • 54
    • 0034920696 scopus 로고    scopus 로고
    • A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis
    • Kalinina T, Riu A, Fischer L, Will H, Sterneck M,. A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. Hepatology 2001; 34 (2): 385-394.
    • (2001) Hepatology , vol.34 , Issue.2 , pp. 385-394
    • Kalinina, T.1    Riu, A.2    Fischer, L.3    Will, H.4    Sterneck, M.5
  • 55
    • 0037105688 scopus 로고    scopus 로고
    • Interpred trial g. Genotype mixtures of hepatitis B virus in patients treated with interferon
    • Hannoun C, Krogsgaard K, Horal P, Lindh M,. Interpred trial g. Genotype mixtures of hepatitis B virus in patients treated with interferon. J Infect Dis 2002; 186 (6): 752-759.
    • (2002) J Infect Dis , vol.186 , Issue.6 , pp. 752-759
    • Hannoun, C.1    Krogsgaard, K.2    Horal, P.3    Lindh, M.4
  • 56
    • 33745597081 scopus 로고    scopus 로고
    • Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam
    • Toan NL, le Song H, Kremsner PG, et al,. Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam. Hepatology 2006; 43 (6): 1375-1384.
    • (2006) Hepatology , vol.43 , Issue.6 , pp. 1375-1384
    • Toan, N.L.1    Le Song, H.2    Kremsner, P.G.3
  • 57
    • 62949167993 scopus 로고    scopus 로고
    • Identification and characterization of genotype A and D recombinant hepatitis B virus from Indian chronic HBV isolates
    • Chauhan R, Kazim SN, Kumar M, Bhattacharjee J, Krishnamoorthy N, Sarin SK,. Identification and characterization of genotype A and D recombinant hepatitis B virus from Indian chronic HBV isolates. World J Gastroenterol 2008; 14 (40): 6228-6236.
    • (2008) World J Gastroenterol , vol.14 , Issue.40 , pp. 6228-6236
    • Chauhan, R.1    Kazim, S.N.2    Kumar, M.3    Bhattacharjee, J.4    Krishnamoorthy, N.5    Sarin, S.K.6
  • 58
    • 84857477877 scopus 로고    scopus 로고
    • A high variability of mixed infections and recent recombinations of hepatitis B virus in Laos
    • Andernach IE, Jutavijittum P, Samountry B, et al,. A high variability of mixed infections and recent recombinations of hepatitis B virus in Laos. PLoS ONE 2012; 7 (2): e30245.
    • (2012) PLoS ONE , vol.7 , Issue.2 , pp. e30245
    • Andernach, I.E.1    Jutavijittum, P.2    Samountry, B.3
  • 59
    • 33646147584 scopus 로고    scopus 로고
    • Phylogenetic analysis of the precore/core gene of hepatitis B virus genotypes e and A in West Africa: New subtypes, mixed infections and recombinations
    • Olinger CM, Venard V, Njayou M, et al,. Phylogenetic analysis of the precore/core gene of hepatitis B virus genotypes E and A in West Africa: new subtypes, mixed infections and recombinations. J Gen Virol 2006; 87 (Pt 5): 1163-1173.
    • (2006) J Gen Virol , vol.87 , Issue.PART 5 , pp. 1163-1173
    • Olinger, C.M.1    Venard, V.2    Njayou, M.3
  • 60
    • 84875994350 scopus 로고    scopus 로고
    • A comparative study of ultra-deep pyrosequencing and cloning to quantitatively analyze the viral quasispecies using hepatitis B virus infection as a model
    • Ramirez C, Gregori J, Buti M, et al,. A comparative study of ultra-deep pyrosequencing and cloning to quantitatively analyze the viral quasispecies using hepatitis B virus infection as a model. Antiviral Res 2013; 98 (2): 273-283.
    • (2013) Antiviral Res , vol.98 , Issue.2 , pp. 273-283
    • Ramirez, C.1    Gregori, J.2    Buti, M.3


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