Identification and characterization of genotype A and D recombinant hepatitis B virus from Indian chronic HBV isolates

World Journal of Gastroenterology

Volumn 14, Issue 40, 2008, Pages 6228-6236

  Chauhan, Ranjit ^a,c   Kazim, Syed Naqui ^b   Kumar, Manoj ^a   Bhattacharjee, Jayashree ^c   Krishnamoorthy, Narayanasamy ^d   Sarin, Shiv Kumar ^a  

^a G B PANT HOSPITAL   (India)

^b JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^c LADY HARDINGE MEDICAL COLLEGE   (India)

^d The Centre for Genomic Application TCGA   (India)

Author keywords

Evolution; Genotype; Hepatitis B virus; Recombination; Variation

Indexed keywords

HEPATITIS B CORE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; HEPATITIS B CORE ANTIGEN; PRESURFACE PROTEIN 2, HEPATITIS B SURFACE ANTIGEN; PROTEIN PRECURSOR; VIRUS DNA;

ADULT; ARTICLE; CHILD; CHRONIC DISEASE; CLINICAL ARTICLE; FEMALE; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC RECOMBINATION; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MALE; NUCLEOTIDE SEQUENCE; PHYLOGENY; SCHOOL CHILD; VIRUS ISOLATION; VIRUS RECOMBINATION; VIRUS STRAIN; AGED; AMINO ACID SEQUENCE; CLASSIFICATION; GENETICS; INDIA; LIVER TUMOR; MIDDLE AGED; MOLECULAR GENETICS; MUTATION; OPEN READING FRAME; VIROLOGY;

ADULT; AGED, 80 AND OVER; AMINO ACID SEQUENCE; CARCINOMA, HEPATOCELLULAR; CHILD; DNA MUTATIONAL ANALYSIS; DNA, VIRAL; FEMALE; GENOTYPE; HEPATITIS B CORE ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; INDIA; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; PHYLOGENY; PROTEIN PRECURSORS; RECOMBINATION, GENETIC; YOUNG ADULT;

EID: 62949167993     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.6228     Document Type: Article

References (46)

1. Wold Health Organization report. Available from URL: http://www.who.org
2. Kramvis A, Kew M, Francois G. Hepatitis B virus genotypes. Vaccine 2005; 23: 2409-2423
3. Norder H, Courouce AM, Magnius LO. Complete genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 1994; 198: 489-503
4. Okamoto H, Tsuda F, Sakugawa H, Sastrosoewignjo RI, Imai M, Miyakawa Y, Mayumi M. Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes. J Gen Virol 1988; 69 (Pt 10): 2575-2583
5. Bollyky PL, Rambaut A, Harvey PH, Holmes EC. Recombination between sequences of hepatitis B virus from different genotypes. J Mol Evol 1996; 42: 97-102
6. Bowyer SM, Sim JG. Relationships within and between genotypes of hepatitis B virus at points across the genome: footprints of recombination in certain isolates. J Gen Virol 2000; 81: 379-392
7. Morozov V, Pisareva M, Groudinin M. Homologous recombination between different genotypes of hepatitis B virus. Gene 2000; 260: 55-65
8. Robertson DL, Sharp PM, McCutchan FE, Hahn BH. Recombination in HIV-1. Nature 1995; 374: 124-126
9. Thakur V, Guptan RC, Kazim SN, Malhotra V, Sarin SK. Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent. J Gastroenterol Hepatol 2002; 17: 165-170
10. Vivekanandan P, Abraham P, Sridharan G, Chandy G, Daniel D, Raghuraman S, Daniel HD, Subramaniam T. Distribution of hepatitis B virus genotypes in blood donors and chronically infected patients in a tertiary care hospital in southern India. Clin Infect Dis 2004; 38: e81-e86
11. Chattopadhyay S, Das BC, Kar P. Hepatitis B virus genotypes in chronic liver disease patients from New Delhi, India. World J Gastroenterol 2006; 12: 6702-6706
12. Chauhan R, Kazim SN, Bhattacharjee J, Sakhuja P, Sarin SK. Basal core promoter, precore region mutations of HBV and their association with e antigen, genotype, and severity of liver disease in patients with chronic hepatitis B in India. J Med Virol 2006; 78: 1047-1054
13. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973; 60: 646-649
14. Gunther S, Li BC, Miska S, Kruger DH, Meisel H, Will H. A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol 1995; 69: 5437-5444
15. Galibert F, Mandart E, Fitoussi F, Tiollais P, Charnay P. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli. Nature 1979; 281: 646-650
16. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997; 25: 4876-4882
17. Kumar S, Tamura K, Nei M. MEGA: Molecular Evolutionary Genetics Analysis software for microcomputers. Comput Appl Biosci 1994; 10: 189-191
18. Lole KS, Bollinger RC, Paranjape RS, Gadkari D, Kulkarni SS, Novak NG, Ingersoll R, Sheppard HW, Ray SC. Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 1999; 73: 152-160
19. Salminen MO, Carr JK, Burke DS, McCutchan FE. Identification of breakpoints in intergenotypic recombinants of HIV type 1 by bootscanning. AIDS Res Hum Retroviruses 1995; 11: 1423-1425
20. Kurbanov F, Tanaka Y, Fujiwara K, Sugauchi F, Mbanya D, Zekeng L, Ndembi N, Ngansop C, Kaptue L, Miura T, Ido E, Hayami M, Ichimura H, Mizokami M. A new subtype (subgenotype) Ac (A3) of hepatitis B virus and recombination between genotypes A and E in Cameroon. J Gen Virol 2005; 86: 2047-2056
21. Cui C, Shi J, Hui L, Xi H, Zhuoma, Quni, Tsedan, Hu G. The dominant hepatitis B virus genotype identified in Tibet is a C/D hybrid. J Gen Virol 2002; 83: 2773-2777
22. Suwannakarn K, Tangkijvanich P, Theamboonlers A, Abe Suwannakarn K, Tangkijvanich P, Theamboonlers A, Abe K, Poovorawan Y. A novel recombinant of Hepatitis B virus genotypes G and C isolated from a Thai patient with hepatocellular carcinoma. J Gen Virol 2005; 86: 3027-3030
23. Wang Z, Liu Z, Zeng G, Wen S, Qi Y, Ma S, Naoumov NV, Hou J. A new intertype recombinant between genotypes C and D of hepatitis B virus identified in China. J Gen Virol 2005; 86: 985-990
24. Sugauchi F, Orito E, Ichida T, Kato H, Sakugawa H, Kakumu S, Ishida T, Chutaputti A, Lai CL, Ueda R, Miyakawa Y, Mizokami M. Hepatitis B virus of genotype B with or without recombination with genotype C over the precore region plus the core gene. J Virol 2002; 76: 5985-5992
25. Hannoun C, Norder H, Lindh M. An aberrant genotype revealed in recombinant hepatitis B virus strains from Vietnam. J Gen Virol 2000; 81: 2267-2272
26. Owiredu WK, Kramvis A, Kew MC. Hepatitis B virus DNA in serum of healthy black African adults positive for hepatitis B surface antibody alone: possible association with recombination between genotypes A and D. J Med Virol 2001; 64: 441-454
27. Simmonds P, Midgley S. Recombination in the genesis and evolution of hepatitis B virus genotypes. J Virol 2005; 79: 15467-15476
28. Yang J, Xing K, Deng R, Wang J, Wang X. Identification of Hepatitis B virus putative intergenotype recombinants by using fragment typing. J Gen Virol 2006; 87: 2203-2215
29. Bahn A, Gerner P, Martine U, Bortolotti F, Wirth S. Detection of different viral strains of hepatitis B virus in chronically infected children after seroconversion from HBsAg to anti-HBs indicating viral persistence. J Hepatol 1997; 27: 973-978
30. Li JS, Tong SP, Wen YM, Vitvitski L, Zhang Q, Trepo C. Hepatitis B virus genotype A rarely circulates as an HBeminus mutant: possible contribution of a single nucleotide in the precore region. J Virol 1993; 67: 5402-5410
31. Mangia A, Chung YH, Hoofnagle JH, Birkenmeyer L, Mushahwar I, Di Bisceglie AM. Pathogenesis of chronic liver disease in patients with chronic hepatitis B virus infection without serum HBeAg. Dig Dis Sci 1996; 41: 2447-2452
32. Kato H, Orito E, Gish RG, Bzowej N, Newsom M, Sugauchi F, Suzuki S, Ueda R, Miyakawa Y, Mizokami M. Hepatitis B e antigen in sera from individuals infected with hepatitis B virus of genotype G. Hepatology 2002; 35: 922-929
33. Toan NL, Song le H, Kremsner PG, Duy DN, Binh VQ, Koeberlein B, Kaiser S, Kandolf R, Torresi J, Bock CT. Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam. Hepatology 2006; 43: 1375-1384
34. Kew MC, Kramvis A, Yu MC, Arakawa K, Hodkinson J. Increased hepatocarcinogenic potential of hepatitis B virus genotype A in Bantu-speaking sub-saharan Africans. J Med Virol 2005; 75: 513-521
35. Sugiyama M, Tanaka Y, Kato T, Orito E, Ito K, Acharya SK, Gish RG, Kramvis A, Shimada T, Izumi N, Kaito M, Miyakawa Y, Mizokami M. Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens. Hepatology 2006; 44: 915-924
36. Sommer G, van Bommel F, Will H. Genotype-specific synthesis and secretion of spliced hepatitis B virus genomes in hepatoma cells. Virology 2000; 271: 371-381
37. Sarin SK, Thakur V, Guptan RC, Saigal S, Malhotra V, Thyagarajan SP, Das BC. Profile of hepatocellular carcinoma in India: an insight into the possible etiologic associations. J Gastroenterol Hepatol 2001; 16: 666-673
38. Caselmann WH, Meyer M, Kekule AS, Lauer U, Hofschneider PH, Koshy R. A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA. Proc Natl Acad Sci USA 1990; 87: 2970-2974
39. Pineau P, Marchio A, Mattei MG, Kim WH, Youn JK, Tiollais P, Dejean A. Extensive analysis of duplicated-inverted hepatitis B virus integrations in human hepatocellular carcinoma. J Gen Virol 1998; 79 (Pt 3): 591-600
40. Zhong S, Chan JY, Yeo W, Tam JS, Johnson PJ. Frequent integration of precore/core mutants of hepatitis B virus in human hepatocellular carcinoma tissues. J Viral Hepat 2000; 7: 115-123
41. Budkowska A, Bedossa P, Groh F, Louise A, Pillot J. Fibronectin of human liver sinusoids binds hepatitis B virus: identification by an anti-idiotypic antibody bearing the internal image of the pre-S2 domain. J Virol 1995; 69: 840-848
42. Ono M, Morisawa K, Nie J, Ota K, Taniguchi T, Saibara T, Onishi S. Transactivation of transforming growth factor alpha gene by hepatitis B virus preS1. Cancer Res 1998; 58: 1813-1816
43. Yang J, Ding X, Zhang Y, Bo X, Zhang M, Wang S. Fibronectin is essential for hepatitis B virus propagation in vitro: may be a potential cellular target? Biochem Biophys Res Commun 2006; 344: 757-764
44. Magnius LO, Norder H. Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Intervirology 1995; 38: 24-34
45. MacDonald DM, Holmes EC, Lewis JC, Simmonds P. Detection of hepatitis B virus infection in wild-born chimpanzees (Pan troglodytes verus): phylogenetic relationships with human and other primate genotypes. J Virol 2000; 74: 4253-4257
46. Simmonds P. The origin and evolution of hepatitis viruses in humans. J Gen Virol 2001; 82: 693-712