Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis

Hepatology

Volumn 29, Issue 3, 1999, Pages 928-938

  Michalak, Tomasz I ^a,b   Pardoe, Ingrid U ^a   Coffin, Carla S ^a   Churchill, Norma D ^a   Freake, Dion S ^a   Smith, Paula ^a   Trelegan, Colleen L ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ELECTROIMMUNOASSAY; FEMALE; FOLLOW UP; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOME; HEPADNAVIRUS; INFECTION RISK; LIVER BIOPSY; LIVER CELL CARCINOMA; LYMPHOID CELL; MALE; MONONUCLEAR CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS CARRIER; VIRUS HEPATITIS; VIRUS INFECTION; VIRUS NUCLEOCAPSID; VIRUS REPLICATION;

EID: 0032978313     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510290329     Document Type: Article

References (8)

1. Blum HE, Liang TJ, Galun E, Wands JR. Persistence of hepatitis B viral DNA after serological recovery from hepatitis B virus infection. HEPATOLOGY 1991;14:56-63.
2. Michalak TI, Pasquinelli C, Guilhot S, Chisari FV. Hepatitis B virus persistence after recovery from acute viral hepatitis. J Clin Invest 1994;93:230-239.
3. Penna A, Artini M, Cavalli A, Levrero M, Bertoletti A, Pilli M, Chisari FV, et al. Long-lasting memory T cell responses following self-limited acute hepatitis B. J Clin Invest 1996;98:1185-1194.
4. Rehermann B, Fowler P, Sidney J, Person J, Redeker A, Brown M, Moss B, Sette A, et al. The cytotoxic T lymphocyte responses to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis. J Exp Med 1995;181:1947-1958.
5. Yotsuyanagi H, Yasuda K, lino S, Moriya K, Shintani Y, Fujie H, Tsutsumi T, et al. Persistent viremia after recovery from self-limited acute hepatitis B. HEPATOLOGY 1998;27:1377-1382.
6. Rehermann B, Ferrari C, Pasquinelli C, Chisari FY The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nat Med 1996;2:1104-1108.
7. Chazouillères O, Mamish D, Kim M, Carey K, Ferrel L, Roberts JP, Ascher ML, et al. "Occult" hepatitis B virus as source of infection in liver transplant recipients. Lancet 1994;343:142-146.
8. Hoofnagle JH, Seeff LB, Buskell-Bales Z, Zimmerman HJ, and the Veterans Administration Hepatitis Cooperative Study Group. Type B hepatitis after transfusion with blood containing antibody to hepatitis B core antigen. N Engl J Med 1978;298:1379-1383.