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Volumn 139, Issue 2, 2010, Pages 491-498

Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B

Author keywords

Antiviral Therapy; Discontinuation; Durability; Sustained Response

Indexed keywords

ADEFOVIR; ALANINE AMINOTRANSFERASE; ENTECAVIR; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; TENOFOVIR; VIRUS DNA; ANTIVIRUS AGENT; BIOLOGICAL MARKER; NUCLEOSIDE; NUCLEOTIDE;

EID: 77955485392     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.03.059     Document Type: Article
Times cited : (178)

References (32)
  • 1
    • 58749111990 scopus 로고    scopus 로고
    • National Institutes of Health Consensus Development Conference Statement: Management of hepatitis B
    • M.F. Sorrell, E.A. Belongia, J. Costa, et al. National Institutes of Health Consensus Development Conference Statement: management of hepatitis B Ann Intern Med 150 2009 104 110
    • (2009) Ann Intern Med , vol.150 , pp. 104-110
    • Sorrell, M.F.1    Belongia, E.A.2    Costa, J.3
  • 2
    • 33645226625 scopus 로고    scopus 로고
    • Chronic hepatitis B in children after e antigen seroclearance: Final report of a 29-year longitudinal study
    • F. Bortolotti, M. Guido, S. Bartolacci, et al. Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study Hepatology 43 2006 556 562
    • (2006) Hepatology , vol.43 , pp. 556-562
    • Bortolotti, F.1    Guido, M.2    Bartolacci, S.3
  • 3
    • 0022644109 scopus 로고
    • Clinical, virologic and histologic outcome following seroconversion from HBeAg to anti-HBe in chronic hepatitis type B
    • G. Fattovich, M. Rugge, L. Brollo, et al. Clinical, virologic and histologic outcome following seroconversion from HBeAg to anti-HBe in chronic hepatitis type B Hepatology 6 1986 167 172
    • (1986) Hepatology , vol.6 , pp. 167-172
    • Fattovich, G.1    Rugge, M.2    Brollo, L.3
  • 4
    • 0019522817 scopus 로고
    • Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis
    • J.H. Hoofnagle, G.M. Dusheiko, L.B. Seeff, et al. Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis Ann Intern Med 94 1981 744 748
    • (1981) Ann Intern Med , vol.94 , pp. 744-748
    • Hoofnagle, J.H.1    Dusheiko, G.M.2    Seeff, L.B.3
  • 5
    • 0036614299 scopus 로고    scopus 로고
    • Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B
    • Y.S. Hsu, R.N. Chien, C.T. Yeh, et al. Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B Hepatology 35 2002 1522 1527
    • (2002) Hepatology , vol.35 , pp. 1522-1527
    • Hsu, Y.S.1    Chien, R.N.2    Yeh, C.T.3
  • 6
    • 0023243960 scopus 로고
    • Spontaneous hepatitis B e antigen to antibody seroconversion and reversion in Chinese patients with chronic hepatitis B virus infection
    • A.S. Lok, C.L. Lai, P.C. Wu, et al. Spontaneous hepatitis B e antigen to antibody seroconversion and reversion in Chinese patients with chronic hepatitis B virus infection Gastroenterology 92 1987 1839 1843
    • (1987) Gastroenterology , vol.92 , pp. 1839-1843
    • Lok, A.S.1    Lai, C.L.2    Wu, P.C.3
  • 7
    • 0035818616 scopus 로고    scopus 로고
    • Serologic and clinical outcomes of 1536 Alaska Natives chronically infected with hepatitis B virus
    • B.J. McMahon, P. Holck, L. Bulkow, et al. Serologic and clinical outcomes of 1536 Alaska Natives chronically infected with hepatitis B virus Ann Intern Med 135 2001 759 768
    • (2001) Ann Intern Med , vol.135 , pp. 759-768
    • McMahon, B.J.1    Holck, P.2    Bulkow, L.3
  • 8
    • 66149173798 scopus 로고    scopus 로고
    • Benefits and risks of nucleoside analog therapy for hepatitis B
    • J.L. Dienstag Benefits and risks of nucleoside analog therapy for hepatitis B Hepatology 49 2009 S112 S121
    • (2009) Hepatology , vol.49
    • Dienstag, J.L.1
  • 9
    • 58149296156 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: Management of chronic hepatitis B
    • European Association for the Study of the L
    • European Association for the Study of the L EASL Clinical Practice Guidelines: management of chronic hepatitis B J Hepatol 50 2009 227 242
    • (2009) J Hepatol , vol.50 , pp. 227-242
  • 10
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • A.S. Lok, and B.J. McMahon Chronic hepatitis B Hepatology 45 2007 507 539
    • (2007) Hepatology , vol.45 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 11
    • 0037381547 scopus 로고    scopus 로고
    • Durability of serologic response after lamivudine treatment of chronic hepatitis B
    • J.L. Dienstag, J. Cianciara, S. Karayalcin, et al. Durability of serologic response after lamivudine treatment of chronic hepatitis B Hepatology 37 2003 748 755
    • (2003) Hepatology , vol.37 , pp. 748-755
    • Dienstag, J.L.1    Cianciara, J.2    Karayalcin, S.3
  • 12
    • 0033797827 scopus 로고    scopus 로고
    • Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea
    • B.C. Song, D.J. Suh, H.C. Lee, et al. Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea Hepatology 32 2000 803 806
    • (2000) Hepatology , vol.32 , pp. 803-806
    • Song, B.C.1    Suh, D.J.2    Lee, H.C.3
  • 13
    • 59149101767 scopus 로고    scopus 로고
    • Sustained durability of HBeAg seroconversion in chronic hepatitis B patients after treatment with telbivudine and lamivudine
    • T. Poynard, J. Hou, A. Chutaputti, et al. Sustained durability of HBeAg seroconversion in chronic hepatitis B patients after treatment with telbivudine and lamivudine J Hepatol 48 2008 S263
    • (2008) J Hepatol , vol.48 , pp. 263
    • Poynard, T.1    Hou, J.2    Chutaputti, A.3
  • 14
    • 48549107919 scopus 로고    scopus 로고
    • Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b
    • E.H. Buster, H.J. Flink, Y. Cakaloglu, et al. Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b Gastroenterology 135 2008 459 467
    • (2008) Gastroenterology , vol.135 , pp. 459-467
    • Buster, E.H.1    Flink, H.J.2    Cakaloglu, Y.3
  • 15
    • 0025734569 scopus 로고
    • Long-term remission of chronic hepatitis B after alpha-interferon therapy
    • J. Korenman, B. Baker, J. Waggoner, et al. Long-term remission of chronic hepatitis B after alpha-interferon therapy Ann Intern Med 114 1991 629 634
    • (1991) Ann Intern Med , vol.114 , pp. 629-634
    • Korenman, J.1    Baker, B.2    Waggoner, J.3
  • 16
    • 66449121130 scopus 로고    scopus 로고
    • Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alfa-2a
    • P. Marcellin, F. Bonino, G.K. Lau, et al. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alfa-2a Gastroenterology 136 2009 2169 2179
    • (2009) Gastroenterology , vol.136 , pp. 2169-2179
    • Marcellin, P.1    Bonino, F.2    Lau, G.K.3
  • 17
    • 29944436855 scopus 로고    scopus 로고
    • Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • C.J. Chen, H.I. Yang, J. Su, et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level JAMA 295 2006 65 73
    • (2006) JAMA , vol.295 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3
  • 18
    • 33644858331 scopus 로고    scopus 로고
    • Predicting cirrhosis risk based on the level of circulating hepatitis B viral load
    • U.H. Iloeje, H.I. Yang, J. Su, et al. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load Gastroenterology 130 2006 678 686
    • (2006) Gastroenterology , vol.130 , pp. 678-686
    • Iloeje, U.H.1    Yang, H.I.2    Su, J.3
  • 19
    • 0033890782 scopus 로고    scopus 로고
    • Development of a quantitative real-time detection assay for hepatitis B virus DNA and comparison with two commercial assays
    • S.D. Pas, E. Fries, R.A. De Man, et al. Development of a quantitative real-time detection assay for hepatitis B virus DNA and comparison with two commercial assays J Clin Microbiol 38 2000 2897 2901
    • (2000) J Clin Microbiol , vol.38 , pp. 2897-2901
    • Pas, S.D.1    Fries, E.2    De Man, R.A.3
  • 20
    • 0036635609 scopus 로고    scopus 로고
    • Detection of HBV DNA using real time analysis
    • S.D. Pas, and H.G. Niesters Detection of HBV DNA using real time analysis J Clin Virol 25 2002 93 94
    • (2002) J Clin Virol , vol.25 , pp. 93-94
    • Pas, S.D.1    Niesters, H.G.2
  • 21
    • 0037316551 scopus 로고    scopus 로고
    • Diagnosing herpesvirus infections by real-time amplification and rapid culture
    • G.J. van Doornum, J. Guldemeester, A.D. Osterhaus, et al. Diagnosing herpesvirus infections by real-time amplification and rapid culture J Clin Microbiol 41 2003 576 580
    • (2003) J Clin Microbiol , vol.41 , pp. 576-580
    • Van Doornum, G.J.1    Guldemeester, J.2    Osterhaus, A.D.3
  • 22
    • 33644878638 scopus 로고    scopus 로고
    • Factors related to post-treatment relapse in chronic hepatitis B patients who lost HBeAg after lamivudine therapy
    • K.S. Byun, O.S. Kwon, J.H. Kim, et al. Factors related to post-treatment relapse in chronic hepatitis B patients who lost HBeAg after lamivudine therapy J Gastroenterol Hepatol 20 2005 1838 1842
    • (2005) J Gastroenterol Hepatol , vol.20 , pp. 1838-1842
    • Byun, K.S.1    Kwon, O.S.2    Kim, J.H.3
  • 23
    • 0142244873 scopus 로고    scopus 로고
    • Determinants for sustained HBeAg response to lamivudine therapy
    • R.N. Chien, C.T. Yeh, S.L. Tsai, et al. Determinants for sustained HBeAg response to lamivudine therapy Hepatology 38 2003 1267 1273
    • (2003) Hepatology , vol.38 , pp. 1267-1273
    • Chien, R.N.1    Yeh, C.T.2    Tsai, S.L.3
  • 24
    • 67349181363 scopus 로고    scopus 로고
    • Durability of antiviral response in HBeAg-positive chronic hepatitis B patients who maintained virologic response for one year after lamivudine discontinuation
    • J.H. Kim, S.J. Lee, M.K. Joo, et al. Durability of antiviral response in HBeAg-positive chronic hepatitis B patients who maintained virologic response for one year after lamivudine discontinuation Dig Dis Sci 54 2009 1572 1577
    • (2009) Dig Dis Sci , vol.54 , pp. 1572-1577
    • Kim, J.H.1    Lee, S.J.2    Joo, M.K.3
  • 25
    • 0036844794 scopus 로고    scopus 로고
    • Durability of lamivudine-induced HBeAg seroconversion for chronic hepatitis B patients with acute exacerbation
    • C.M. Lee, G.Y. Ong, S.N. Lu, et al. Durability of lamivudine-induced HBeAg seroconversion for chronic hepatitis B patients with acute exacerbation J Hepatol 37 2002 669 674
    • (2002) J Hepatol , vol.37 , pp. 669-674
    • Lee, C.M.1    Ong, G.Y.2    Lu, S.N.3
  • 26
    • 0345096466 scopus 로고    scopus 로고
    • Quantitative polymerase chain reaction assay for serum hepatitis B virus DNA as a predictive factor for post-treatment relapse after lamivudine induced hepatitis B e antigen loss or seroconversion
    • H.C. Lee, D.J. Suh, S.H. Ryu, et al. Quantitative polymerase chain reaction assay for serum hepatitis B virus DNA as a predictive factor for post-treatment relapse after lamivudine induced hepatitis B e antigen loss or seroconversion Gut 52 2003 1779 1783
    • (2003) Gut , vol.52 , pp. 1779-1783
    • Lee, H.C.1    Suh, D.J.2    Ryu, S.H.3
  • 27
    • 0036906811 scopus 로고    scopus 로고
    • Effect of virological response on post-treatment durability of lamivudine-induced HBeAg seroconversion
    • K.M. Lee, S.W. Cho, S.W. Kim, et al. Effect of virological response on post-treatment durability of lamivudine-induced HBeAg seroconversion J Viral Hepat 9 2002 208 212
    • (2002) J Viral Hepat , vol.9 , pp. 208-212
    • Lee, K.M.1    Cho, S.W.2    Kim, S.W.3
  • 28
    • 12444287949 scopus 로고    scopus 로고
    • Long-term additional lamivudine therapy enhances durability of lamivudine-induced HBeAg loss: A prospective study
    • S.H. Ryu, Y.H. Chung, M.H. Choi, et al. Long-term additional lamivudine therapy enhances durability of lamivudine-induced HBeAg loss: a prospective study J Hepatol 39 2003 614 619
    • (2003) J Hepatol , vol.39 , pp. 614-619
    • Ryu, S.H.1    Chung, Y.H.2    Choi, M.H.3
  • 29
    • 0037371186 scopus 로고    scopus 로고
    • Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B: Relation to type of therapy and pretreatment serum hepatitis B virus DNA and alanine aminotransferase
    • A.B. van Nunen, B.E. Hansen, D.J. Suh, et al. Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B: relation to type of therapy and pretreatment serum hepatitis B virus DNA and alanine aminotransferase Gut 52 2003 420 424
    • (2003) Gut , vol.52 , pp. 420-424
    • Van Nunen, A.B.1    Hansen, B.E.2    Suh, D.J.3
  • 30
    • 54249142122 scopus 로고    scopus 로고
    • Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment: Analysis of precore and basal core promoter mutants
    • I.C. Wu, M.L. Shiffman, M.J. Tong, et al. Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment: analysis of precore and basal core promoter mutants Clin Infect Dis 47 2008 1305 1311
    • (2008) Clin Infect Dis , vol.47 , pp. 1305-1311
    • Wu, I.C.1    Shiffman, M.L.2    Tong, M.J.3
  • 31
    • 22344438967 scopus 로고    scopus 로고
    • Long-term results of lamivudine monotherapy in Korean patients with HBeAg-positive chronic hepatitis B: Response and relapse rates, and factors related to durability of HBeAg seroconversion
    • S.K. Yoon, J.W. Jang, C.W. Kim, et al. Long-term results of lamivudine monotherapy in Korean patients with HBeAg-positive chronic hepatitis B: response and relapse rates, and factors related to durability of HBeAg seroconversion Intervirology 48 2005 341 349
    • (2005) Intervirology , vol.48 , pp. 341-349
    • Yoon, S.K.1    Jang, J.W.2    Kim, C.W.3
  • 32
    • 68349125344 scopus 로고    scopus 로고
    • To "be" or not to "be": That is the question
    • C.T. Frenette, and R.G. Gish To "be" or not to "be": that is the question Am J Gastroenterol 104 2009 1948 1952
    • (2009) Am J Gastroenterol , vol.104 , pp. 1948-1952
    • Frenette, C.T.1    Gish, R.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.