Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Kilpatrick, Kiri ^a   Zeng, Yimeng ^a   Hancock, Tommy ^a   Segatori, Laura ^a,b  

^a Rice University   (United States)

^b RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ALPHA SYNUCLEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; BETA CYCLODEXTRIN DERIVATIVE; PROTEIN AGGREGATE; SMALL INTERFERING RNA; TFEB PROTEIN, HUMAN;

ARTICLE; AUTOPHAGY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG ACTIVATION; DRUG PROTEIN BINDING; DRUG TARGETING; GENE ACTIVATION; GENE FUNCTION; GENE OVEREXPRESSION; GLIOMA CELL; HUMAN; HUMAN CELL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TFEB GENE; TRANSCRIPTION REGULATION; UPREGULATION; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; GENE SILENCING; GENETICS; LYSOSOME; METABOLISM; TUMOR CELL LINE;

ALPHA-SYNUCLEIN; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA-CYCLODEXTRINS; CELL LINE, TUMOR; GENE SILENCING; HUMANS; LYSOSOMES; PROTEIN AGGREGATES; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84925597891     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120819     Document Type: Article

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