메뉴 건너뛰기




Volumn 72, Issue 4, 2015, Pages 659-671

Formation and role of exosomes in cancer

Author keywords

Biogenesis; ESCRT; Fibroblast; Immunosurveillance; Multivesicular endosome; Signaling; Targeted therapy; Vaccine

Indexed keywords

DENDRITIC CELL VACCINE; TUMOR MARKER; CANCER VACCINE; ESCRT PROTEIN;

EID: 84925511573     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1764-3     Document Type: Review
Times cited : (205)

References (141)
  • 1
    • 84871511126 scopus 로고    scopus 로고
    • Deaths: Preliminary data for 2011
    • 24984457
    • Hoyert DL, Xu J (2012) Deaths: preliminary data for 2011. Natl Vital Stat Rep 61:1-52
    • (2012) Natl Vital Stat Rep , vol.61 , pp. 1-52
    • Hoyert, D.L.1    Xu, J.2
  • 2
    • 84865580177 scopus 로고    scopus 로고
    • Deaths: Leading causes for 2009
    • 24964584
    • Heron M (2012) Deaths: leading causes for 2009. Natl Vital Stat Rep 61:1-94
    • (2012) Natl Vital Stat Rep , vol.61 , pp. 1-94
    • Heron, M.1
  • 3
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • 2206719 17705880
    • DeNardo DG, Coussens LM (2007) Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res 9:212
    • (2007) Breast Cancer Res , vol.9 , pp. 212
    • Denardo, D.G.1    Coussens, L.M.2
  • 5
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • 1:CAS:528:DC%2BC3MXivVGnsLg%3D 3569482 21383745
    • Bissell MJ, Hines WC (2011) Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med 17:320-329
    • (2011) Nat Med , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 6
    • 84872071400 scopus 로고    scopus 로고
    • Arousal of cancer-associated stromal fibroblasts: Palladin-activated fibroblasts promote tumor invasion
    • 3547892 23076142
    • Brentnall TA (2012) Arousal of cancer-associated stromal fibroblasts: palladin-activated fibroblasts promote tumor invasion. Cell Adh Migr 6:488-494
    • (2012) Cell Adh Migr , vol.6 , pp. 488-494
    • Brentnall, T.A.1
  • 7
    • 34447276000 scopus 로고    scopus 로고
    • Tumor microenvironment: The role of the tumor stroma in cancer
    • 1:CAS:528:DC%2BD2sXnvVSqu7w%3D
    • Li H, Fan X, Houghton J (2007) Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biohem 101:805-815
    • (2007) J Cell Biohem , vol.101 , pp. 805-815
    • Li, H.1    Fan, X.2    Houghton, J.3
  • 8
    • 84873434819 scopus 로고    scopus 로고
    • Treatment-induced secretion of WNT16B promoted tumor growth and acquired resistance to chemotherapy: Implications for potential use of inhibitors in cancer treatment
    • 1:CAS:528:DC%2BC3sXktFOmtb4%3D 3572004 23114711
    • Johnson LM, Price DK, Figg WD (2013) Treatment-induced secretion of WNT16B promoted tumor growth and acquired resistance to chemotherapy: implications for potential use of inhibitors in cancer treatment. Cancer Biol Ther 14:90-91
    • (2013) Cancer Biol Ther , vol.14 , pp. 90-91
    • Johnson, L.M.1    Price, D.K.2    Figg, W.D.3
  • 9
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • 1:CAS:528:DC%2BC38Xkt1ykt7w%3D 22439926
    • Hanahan D, Coussens LM (2012) Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21:309-322
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 10
    • 68549112896 scopus 로고    scopus 로고
    • Tumor stroma derived biomarkers in cancer
    • 19259624
    • Sund M, Kalluri R (2009) Tumor stroma derived biomarkers in cancer. Cancer Metastasis Rev 28:177-183
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 177-183
    • Sund, M.1    Kalluri, R.2
  • 11
    • 84861186736 scopus 로고    scopus 로고
    • Jekyll and Hyde: The role of the microenvironment on the progression of cancer
    • 1:CAS:528:DC%2BC3MXltlehsQ%3D%3D 21125673
    • Allen M, Louis Jones J (2011) Jekyll and Hyde: the role of the microenvironment on the progression of cancer. J Pathol 223:162-176
    • (2011) J Pathol , vol.223 , pp. 162-176
    • Allen, M.1    Louis Jones, J.2
  • 12
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes: Bipolar effects of the tumour stroma in cancer
    • 1:CAS:528:DC%2BD2cXptFegt78%3D 15516957
    • Mueller MM, Fusenig NE (2004) Friends or foes: bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 4:839-849
    • (2004) Nat Rev Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 13
    • 20444412646 scopus 로고    scopus 로고
    • Therapeutic targeting of the tumor microenvironment
    • 1:CAS:528:DC%2BD2MXlslCgsro%3D 15950901
    • Joyce JA (2005) Therapeutic targeting of the tumor microenvironment. Cancer Cell 7:513-520
    • (2005) Cancer Cell , vol.7 , pp. 513-520
    • Joyce, J.A.1
  • 14
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • 1:CAS:528:DC%2BD3MXktVSjs70%3D 11357146
    • Rosenberg SA (2001) Progress in human tumour immunology and immunotherapy. Nature 411:380-384
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.A.1
  • 15
    • 33846531356 scopus 로고    scopus 로고
    • The tumour microenvironment as a target for chemoprevention
    • 1:CAS:528:DC%2BD2sXotFOjuw%3D%3D 17218951
    • Albini A, Sporn MB (2007) The tumour microenvironment as a target for chemoprevention. Nat Rev Cancer 7:139-147
    • (2007) Nat Rev Cancer , vol.7 , pp. 139-147
    • Albini, A.1    Sporn, M.B.2
  • 16
    • 84900840898 scopus 로고    scopus 로고
    • Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress
    • Kucharzewska P, Belting M (2013) Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress. J Extracell Vesicles. doi: 10.3402/jev.v2i0.20304
    • (2013) J Extracell Vesicles
    • Kucharzewska, P.1    Belting, M.2
  • 18
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • 19498381
    • Théry C, Ostrowski M, Segura E (2009) Membrane vesicles as conveyors of immune responses. Nat Rev Immunol 9:581-593
    • (2009) Nat Rev Immunol , vol.9 , pp. 581-593
    • Théry, C.1    Ostrowski, M.2    Segura, E.3
  • 19
    • 77951762023 scopus 로고    scopus 로고
    • Structural-mechanical characterization of nanoparticle exosomes in human saliva, using correlative AFM, FESEM, and force spectroscopy
    • 1:CAS:528:DC%2BC3cXjtVygt70%3D 2866049 20218655
    • Sharma S, Rasool HI, Palanisamy V, Mathisen C, Schmidt M, Wong DT, Gimzewski JK (2010) Structural-mechanical characterization of nanoparticle exosomes in human saliva, using correlative AFM, FESEM, and force spectroscopy. ACS Nano 4:1921-1926
    • (2010) ACS Nano , vol.4 , pp. 1921-1926
    • Sharma, S.1    Rasool, H.I.2    Palanisamy, V.3    Mathisen, C.4    Schmidt, M.5    Wong, D.T.6    Gimzewski, J.K.7
  • 20
    • 59249089695 scopus 로고    scopus 로고
    • Shedding microvesicles: Artefacts no more
    • 1:CAS:528:DC%2BD1MXhs1amt7Y%3D 19144520
    • Cocucci E, Racchetti G, Meldolesi J (2009) Shedding microvesicles: artefacts no more. Trends Cell Biol 19:43-51
    • (2009) Trends Cell Biol , vol.19 , pp. 43-51
    • Cocucci, E.1    Racchetti, G.2    Meldolesi, J.3
  • 21
    • 84894189683 scopus 로고    scopus 로고
    • Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer
    • 1:CAS:528:DC%2BC2cXisFWjt74%3D 24398677
    • Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R (2014) Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. J Biol Chem 289:3869-3875
    • (2014) J Biol Chem , vol.289 , pp. 3869-3875
    • Kahlert, C.1    Melo, S.A.2    Protopopov, A.3    Tang, J.4    Seth, S.5    Koch, M.6    Zhang, J.7    Weitz, J.8    Chin, L.9    Futreal, A.10    Kalluri, R.11
  • 22
    • 84858444838 scopus 로고    scopus 로고
    • ExoCarta 2012: Database of exosomal proteins, RNA and lipids
    • 1:CAS:528:DC%2BC3MXhs12htbzJ 3245025 21989406
    • Mathivanan S, Fahner CJ, Reid GE, Simpson RJ (2012) ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucl Acids Res 40:D1241-D1244
    • (2012) Nucl Acids Res , vol.40 , pp. 1241-D1244
    • Mathivanan, S.1    Fahner, C.J.2    Reid, G.E.3    Simpson, R.J.4
  • 25
    • 0019874126 scopus 로고
    • Exfoliation of membrane ecto-enzymes in the form of micro-vesicles
    • 1:CAS:528:DyaL3MXksFyrtrc%3D 6266476
    • Trams EG, Lauter CJ, Salem N Jr, Heine U (1981) Exfoliation of membrane ecto-enzymes in the form of micro-vesicles. Biochim Biophys Acta 645:63-70
    • (1981) Biochim Biophys Acta , vol.645 , pp. 63-70
    • Trams, E.G.1    Lauter, C.J.2    Salem, Jr.N.3    Heine, U.4
  • 26
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: Composition, biogenesis and function
    • 12154376
    • Théry C, Zitvogel L, Amigorena S (2002) Exosomes: composition, biogenesis and function. Nat Rev Immunol 2:569-579
    • (2002) Nat Rev Immunol , vol.2 , pp. 569-579
    • Théry, C.1    Zitvogel, L.2    Amigorena, S.3
  • 27
    • 0017762189 scopus 로고
    • Spontaneous shedding of plasma membrane fragments by human cells in vivo and in vitro
    • 923096
    • De Broe ME, Wieme RJ, Logghe GN, Roels F (1977) Spontaneous shedding of plasma membrane fragments by human cells in vivo and in vitro. Clin Chim Acta 81:237-245
    • (1977) Clin Chim Acta , vol.81 , pp. 237-245
    • De Broe, M.E.1    Wieme, R.J.2    Logghe, G.N.3    Roels, F.4
  • 29
    • 84890458696 scopus 로고    scopus 로고
    • Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles
    • 1:CAS:528:DC%2BC2cXhtFyksLY%3D 24105262
    • Colombo M, Moita C, van Niel G, Kowal J, Vigneron J, Benaroch P, Manel N, Moita LF, Théry C, Raposo G (2013) Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci 126:5553-5565
    • (2013) J Cell Sci , vol.126 , pp. 5553-5565
    • Colombo, M.1    Moita, C.2    Van Niel, G.3    Kowal, J.4    Vigneron, J.5    Benaroch, P.6    Manel, N.7    Moita, L.F.8    Théry, C.9    Raposo, G.10
  • 30
    • 84889239323 scopus 로고    scopus 로고
    • Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes
    • 24231649
    • Kajimoto T, Okada T, Miya S, Zhang L, Nakamura S (2013) Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes. Nat Commun 4:2712
    • (2013) Nat Commun , vol.4 , pp. 2712
    • Kajimoto, T.1    Okada, T.2    Miya, S.3    Zhang, L.4    Nakamura, S.5
  • 33
    • 33646416463 scopus 로고    scopus 로고
    • The regulation of exosome secretion: A novel function of the p53 protein
    • 1:CAS:528:DC%2BD28XjvF2kt74%3D 16651434
    • Yu X, Harris SL, Levine AJ (2006) The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res 66:4795-4801
    • (2006) Cancer Res , vol.66 , pp. 4795-4801
    • Yu, X.1    Harris, S.L.2    Levine, A.J.3
  • 34
    • 54049088501 scopus 로고    scopus 로고
    • Exosome secretion, including DNA damage-induced p53-dependent secretory pathway, is severly compromised in TSAP6/Steap3-null mice
    • 1:CAS:528:DC%2BD1cXht1aru7zK 18617898
    • Lespagnol A, Duflaut D, Beekman C, Blanc L, Fiucci G, Marine JC, Vidal M, Amson R, Telerman A (2008) Exosome secretion, including DNA damage-induced p53-dependent secretory pathway, is severly compromised in TSAP6/Steap3-null mice. Cell Death Differ 15:1723-1733
    • (2008) Cell Death Differ , vol.15 , pp. 1723-1733
    • Lespagnol, A.1    Duflaut, D.2    Beekman, C.3    Blanc, L.4    Fiucci, G.5    Marine, J.C.6    Vidal, M.7    Amson, R.8    Telerman, A.9
  • 35
    • 84875994843 scopus 로고    scopus 로고
    • Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes
    • 1:CAS:528:DC%2BC3sXlsVCqsbc%3D 3617250 23430739
    • Thompson CA, Purushothaman A, Ramani VC, Vlodavsky I, Sanderson RD (2013) Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes. J Biol Chem 288(14):10093-10099
    • (2013) J Biol Chem , vol.288 , Issue.14 , pp. 10093-10099
    • Thompson, C.A.1    Purushothaman, A.2    Ramani, V.C.3    Vlodavsky, I.4    Sanderson, R.D.5
  • 36
    • 84896700681 scopus 로고    scopus 로고
    • Regulation of exosome release from mammary epithelial and breast cancer cells: A new regulatory pathway
    • 1:CAS:528:DC%2BC2cXhtlKis7Y%3D 24462375
    • Riches A, Campbell E, Borger E, Powis S (2014) Regulation of exosome release from mammary epithelial and breast cancer cells: a new regulatory pathway. Eur J Cancer 50:1025-1034
    • (2014) Eur J Cancer , vol.50 , pp. 1025-1034
    • Riches, A.1    Campbell, E.2    Borger, E.3    Powis, S.4
  • 39
    • 84888384111 scopus 로고    scopus 로고
    • Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer
    • 1:CAS:528:DC%2BC3sXhvFemur%2FE 3845200 24218614
    • Shin SJ, Smith JA, Rezniczek GA, Pan S, Chen R, Brentnall TA, Wiche G, Kelly KA (2013) Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Proc Natl Acad Sci USA 110:19414-19419
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 19414-19419
    • Shin, S.J.1    Smith, J.A.2    Rezniczek, G.A.3    Pan, S.4    Chen, R.5    Brentnall, T.A.6    Wiche, G.7    Kelly, K.A.8
  • 40
    • 0037096162 scopus 로고    scopus 로고
    • The exosome pathway in K562 cells is regulated by Rab11
    • 1:CAS:528:DC%2BD38XlsVCqur4%3D 12045221
    • Savina A, Vidal M, Colombo MI (2002) The exosome pathway in K562 cells is regulated by Rab11. J Cell Sci 115:2505-2515
    • (2002) J Cell Sci , vol.115 , pp. 2505-2515
    • Savina, A.1    Vidal, M.2    Colombo, M.I.3
  • 41
    • 12744269555 scopus 로고    scopus 로고
    • Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner
    • 1:CAS:528:DC%2BD2MXhtVWmsr4%3D 15634213
    • Savina A, Fader CM, Damiani MT, Colombo MI (2005) Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic 6:131-143
    • (2005) Traffic , vol.6 , pp. 131-143
    • Savina, A.1    Fader, C.M.2    Damiani, M.T.3    Colombo, M.I.4
  • 43
    • 0035253742 scopus 로고    scopus 로고
    • Know thy neighbor: Stromal cells can contribute oncogenic signals
    • 1:CAS:528:DC%2BD3MXhtFSntLw%3D 11163151
    • Tlsty TD, Hein PW (2001) Know thy neighbor: stromal cells can contribute oncogenic signals. Curr Opin Genet Dev 11:54-59
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 54-59
    • Tlsty, T.D.1    Hein, P.W.2
  • 44
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • 1:CAS:528:DC%2BD2MXktlSiu7w%3D 15882617
    • Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA (2005) Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121:335-348
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 46
    • 0025875889 scopus 로고
    • Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts
    • 1:STN:280:DyaK3M3pt1Crtg%3D%3D 1712249
    • Gleave M, Hsieh JT, Gao CA, von Eschenbach AC, Chung LW (1991) Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts. Cancer Res 51:3753-3761
    • (1991) Cancer Res , vol.51 , pp. 3753-3761
    • Gleave, M.1    Hsieh, J.T.2    Gao, C.A.3    Von Eschenbach, A.C.4    Chung, L.W.5
  • 47
    • 0036605095 scopus 로고    scopus 로고
    • Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts
    • 1:CAS:528:DC%2BD38XjsFansL4%3D 11992541
    • Kanekura T, Chen X, Kanzaki T (2002) Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer 99:520-528
    • (2002) Int J Cancer , vol.99 , pp. 520-528
    • Kanekura, T.1    Chen, X.2    Kanzaki, T.3
  • 48
    • 0034285090 scopus 로고    scopus 로고
    • Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts
    • 1:CAS:528:DC%2BD3cXlsFCju78%3D 10936678
    • Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S (2000) Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. Cancer Lett 157:177-184
    • (2000) Cancer Lett , vol.157 , pp. 177-184
    • Sameshima, T.1    Nabeshima, K.2    Toole, B.P.3    Yokogami, K.4    Okada, Y.5    Goya, T.6    Koono, M.7    Wakisaka, S.8
  • 49
    • 84871451335 scopus 로고    scopus 로고
    • Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway
    • Gu J, Qian H, Shen L, Zhang X, Zhu W, Huang L, Yan Y, Mao F, Zhao C, Shi Y, Xu W (2012) Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway. PLoS One. doi: 10.1371/journal.pone.0052465
    • (2012) PLoS One
    • Gu, J.1    Qian, H.2    Shen, L.3    Zhang, X.4    Zhu, W.5    Huang, L.6    Yan, Y.7    Mao, F.8    Zhao, C.9    Shi, Y.10    Xu, W.11
  • 50
    • 78649958307 scopus 로고    scopus 로고
    • Cancer exosomes trigger fibroblast to myofibroblast differentiation
    • 1:CAS:528:DC%2BC3cXhsFamur3E 21098712
    • Webber J, Steadman R, Mason MD, Tabi Z, Clayton A (2010) Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res 70:9621-9630
    • (2010) Cancer Res , vol.70 , pp. 9621-9630
    • Webber, J.1    Steadman, R.2    Mason, M.D.3    Tabi, Z.4    Clayton, A.5
  • 52
    • 0031586362 scopus 로고    scopus 로고
    • Fibroblasts can modulate the phenotype of malignant epithelial cells in vitro
    • 1:CAS:528:DyaK2sXlvVKgt7k%3D 9281367
    • Atula S, Grenman R, Syrjänen S (1997) Fibroblasts can modulate the phenotype of malignant epithelial cells in vitro. Exp Cell Res 235(1):180-187
    • (1997) Exp Cell Res , vol.235 , Issue.1 , pp. 180-187
    • Atula, S.1    Grenman, R.2    Syrjänen, S.3
  • 53
    • 33746886963 scopus 로고    scopus 로고
    • Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029
    • 1:CAS:528:DC%2BD28XmvFGkt70%3D 16849554
    • Gesierich S, Berezovskiy I, Ryschich E, Zöller M (2006) Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029. Cancer Res 66:7083-7094
    • (2006) Cancer Res , vol.66 , pp. 7083-7094
    • Gesierich, S.1    Berezovskiy, I.2    Ryschich, E.3    Zöller, M.4
  • 54
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • 1:CAS:528:DC%2BD3sXktFOnsb8%3D 12778130
    • Bergers G, Benjamin LE (2003) Tumorigenesis and the angiogenic switch. Nat Rev Cancer 3:401-410
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 55
    • 0035253409 scopus 로고    scopus 로고
    • Angiogenesis: The role of the microenvironment in flipping the switch
    • 1:CAS:528:DC%2BD3MXhtFSnt7k%3D 11163148
    • Giordano FJ, Johnson RS (2001) Angiogenesis: the role of the microenvironment in flipping the switch. Curr Opin Genet Dev 11:35-40
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 35-40
    • Giordano, F.J.1    Johnson, R.S.2
  • 56
    • 77953142134 scopus 로고    scopus 로고
    • Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
    • 1:CAS:528:DC%2BC3cXpsFCrt7g%3D 2877972 20124223
    • Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK (2010) Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics 9:1085-1099
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1085-1099
    • Park, J.E.1    Tan, H.S.2    Datta, A.3    Lai, R.C.4    Zhang, H.5    Meng, W.6    Lim, S.K.7    Sze, S.K.8
  • 62
    • 0037443410 scopus 로고    scopus 로고
    • Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
    • 1:CAS:528:DC%2BD3sXhslOrs7s%3D 12626558
    • Skokos D, Botros HG, Demeure C, Morin J, Peronet R, Birkenmeier G, Boudaly S, Mécheri S (2003) Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J Immunol 170:3037-3045
    • (2003) J Immunol , vol.170 , pp. 3037-3045
    • Skokos, D.1    Botros, H.G.2    Demeure, C.3    Morin, J.4    Peronet, R.5    Birkenmeier, G.6    Boudaly, S.7    Mécheri, S.8
  • 64
    • 34248216649 scopus 로고    scopus 로고
    • Tumor-released microvesicles as vehicles of immunosuppression
    • 1:CAS:528:DC%2BD2sXksVGlt7o%3D 17409393
    • Valenti R, Huber V, Iero M, Filipazzi P, Parmiani G, Rivoltini L (2007) Tumor-released microvesicles as vehicles of immunosuppression. Cancer Res 67:2912-2915
    • (2007) Cancer Res , vol.67 , pp. 2912-2915
    • Valenti, R.1    Huber, V.2    Iero, M.3    Filipazzi, P.4    Parmiani, G.5    Rivoltini, L.6
  • 67
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
    • 1:CAS:528:DC%2BD28XotVCmuw%3D%3D 16168663
    • Serafini P, Borrello I, Bronte V (2006) Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol 16:53-65
    • (2006) Semin Cancer Biol , vol.16 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 68
    • 77952042113 scopus 로고    scopus 로고
    • Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells
    • 1:CAS:528:DC%2BC3cXmvFSqurY%3D 2861113 20348242
    • Liu Y, Xiang X, Zhuang X, Zhang S, Liu C, Cheng Z, Michalek S, Grizzle W, Zhang HG (2010) Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells. Am J Pathol 176:2490-2499
    • (2010) Am J Pathol , vol.176 , pp. 2490-2499
    • Liu, Y.1    Xiang, X.2    Zhuang, X.3    Zhang, S.4    Liu, C.5    Cheng, Z.6    Michalek, S.7    Grizzle, W.8    Zhang, H.G.9
  • 69
    • 84876146710 scopus 로고    scopus 로고
    • Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells
    • 1:CAS:528:DC%2BC38XhvVGls7jP 23184679
    • Hong EH, Chang SY, Lee BR, Kim YS, Lee JM, Kang CY, Kweon MN, Ko HJ (2013) Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells. Int J Cancer 132:2839-2848
    • (2013) Int J Cancer , vol.132 , pp. 2839-2848
    • Hong, E.H.1    Chang, S.Y.2    Lee, B.R.3    Kim, Y.S.4    Lee, J.M.5    Kang, C.Y.6    Kweon, M.N.7    Ko, H.J.8
  • 70
    • 77957364754 scopus 로고    scopus 로고
    • TLR2-mediated expansion of MDSCs is dependent on the source of tumor exosomes
    • 1:CAS:528:DC%2BC3cXhsVSqu7vL 2947257 20802178
    • Xiang X, Liu Y, Zhuang X, Zhang S, Michalek S, Taylor DD, Grizzle W, Zhang HG (2010) TLR2-mediated expansion of MDSCs is dependent on the source of tumor exosomes. Am J Pathol 177:1606-1610
    • (2010) Am J Pathol , vol.177 , pp. 1606-1610
    • Xiang, X.1    Liu, Y.2    Zhuang, X.3    Zhang, S.4    Michalek, S.5    Taylor, D.D.6    Grizzle, W.7    Zhang, H.G.8
  • 71
    • 38949153176 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: The new mechanism of immunosuppression in cancer
    • Luczyński W, Krawczuk-Rybak M, Stasiak-Barmuta A (2008) Myeloid-derived suppressor cells: the new mechanism of immunosuppression in cancer. Postepy Hig Med Dosw 62:18-22
    • (2008) Postepy Hig Med Dosw , vol.62 , pp. 18-22
    • Luczyński, W.1    Krawczuk-Rybak, M.2    Stasiak-Barmuta, A.3
  • 72
    • 84906212452 scopus 로고    scopus 로고
    • Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma
    • [Epub ahead of print]
    • Ye SB, Li ZL, Luo DH, Huang BJ, Chen YS, Zhang XS, Cui J, Zeng YX, Li J (2014) Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma. Oncotarget [Epub ahead of print]
    • (2014) Oncotarget
    • Ye, S.B.1    Li, Z.L.2    Luo, D.H.3    Huang, B.J.4    Chen, Y.S.5    Zhang, X.S.6    Cui, J.7    Zeng, Y.X.8    Li, J.9
  • 73
    • 34547686145 scopus 로고    scopus 로고
    • Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2
    • 1:CAS:528:DC%2BD2sXosVemtLc%3D 17671216
    • Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z (2007) Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2. Cancer Res 67:7458-7466
    • (2007) Cancer Res , vol.67 , pp. 7458-7466
    • Clayton, A.1    Mitchell, J.P.2    Court, J.3    Mason, M.D.4    Tabi, Z.5
  • 76
    • 84860451203 scopus 로고    scopus 로고
    • Exosomes released from Mycoplasma infected tumor cells activate inhibitory B cells
    • Yang C, Chalasani G, Ng YH, Robbins PD (2012) Exosomes released from Mycoplasma infected tumor cells activate inhibitory B cells. PLoS One. doi: 10.1371/journal.pone.0036138
    • (2012) PLoS One
    • Yang, C.1    Chalasani, G.2    Ng, Y.H.3    Robbins, P.D.4
  • 77
    • 0031863680 scopus 로고    scopus 로고
    • B cells inhibit induction of T cell-dependent tumor immunity
    • 1:CAS:528:DyaK1cXjtFKgtrY%3D 9585241
    • Qin Z, Richter G, Schüler T, Ibe S, Cao X, Blankenstein T (1998) B cells inhibit induction of T cell-dependent tumor immunity. Nat Med 4:627-630
    • (1998) Nat Med , vol.4 , pp. 627-630
    • Qin, Z.1    Richter, G.2    Schüler, T.3    Ibe, S.4    Cao, X.5    Blankenstein, T.6
  • 78
    • 84926262086 scopus 로고    scopus 로고
    • Cancer exosomes and NKG2D receptor-ligand interactions: Impairing NKG2D-mediated cytotoxicity and anti-tumour immune surveillance
    • Mincheva-Nilsson L, Baranov V (2014) Cancer exosomes and NKG2D receptor-ligand interactions: impairing NKG2D-mediated cytotoxicity and anti-tumour immune surveillance. Semin Cancer Biol. doi: 10.1016/j.semcancer.2014.02.010
    • (2014) Semin Cancer Biol
    • Mincheva-Nilsson, L.1    Baranov, V.2
  • 79
    • 76549099879 scopus 로고    scopus 로고
    • Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA008 that is shed by tumor cells in exosomes
    • 1:CAS:528:DC%2BC3cXltlWktQ%3D%3D 2817492 20068167
    • Ashiru O, Boutet P, Fernández-Messina L, Agüera-González S, Skepper JN, Valés-Gómez M, Reyburn HT (2010) Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA008 that is shed by tumor cells in exosomes. Cancer Res 70:481-489
    • (2010) Cancer Res , vol.70 , pp. 481-489
    • Ashiru, O.1    Boutet, P.2    Fernández-Messina, L.3    Agüera-González, S.4    Skepper, J.N.5    Valés-Gómez, M.6    Reyburn, H.T.7
  • 81
    • 84926247911 scopus 로고    scopus 로고
    • Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation
    • Altevogt P, Bretz NP, Ridinger J, Utikal J, Umansky V (2014) Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation. Semin Cancer Biol. doi: 10.1016/j.semcancer.2014.04.008
    • (2014) Semin Cancer Biol
    • Altevogt, P.1    Bretz, N.P.2    Ridinger, J.3    Utikal, J.4    Umansky, V.5
  • 82
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • 12492492
    • Fidler IJ (2002) The organ microenvironment and cancer metastasis. Differentiation 70:498-505
    • (2002) Differentiation , vol.70 , pp. 498-505
    • Fidler, I.J.1
  • 83
    • 84895744810 scopus 로고    scopus 로고
    • Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors
    • 1:CAS:528:DC%2BC2cXisFOhs7Y%3D 24376083
    • Jeppesen DK, Nawrocki A, Jensen SG, Thorsen K, Whitehead B, Howard KA, Dyrskjøt L, Ørntoft TF, Larsen MR, Ostenfeld MS (2014) Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors. Proteomics 14:699-712
    • (2014) Proteomics , vol.14 , pp. 699-712
    • Jeppesen, D.K.1    Nawrocki, A.2    Jensen, S.G.3    Thorsen, K.4    Whitehead, B.5    Howard, K.A.6    Dyrskjøt, L.7    Ørntoft, T.F.8    Larsen, M.R.9    Ostenfeld, M.S.10
  • 85
    • 33751074452 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 in human breast and prostate cancer
    • 1:CAS:528:DC%2BD28XhtlequrzN 16954428
    • Kimbro KS, Simons JW (2006) Hypoxia-inducible factor-1 in human breast and prostate cancer. Endocr Relat Cancer 13:739-749
    • (2006) Endocr Relat Cancer , vol.13 , pp. 739-749
    • Kimbro, K.S.1    Simons, J.W.2
  • 87
    • 84879603956 scopus 로고    scopus 로고
    • Metastasis: New insights into organ-specific extravasation and metastatic niches
    • Irmisch A, Huelsken J (2013) Metastasis: new insights into organ-specific extravasation and metastatic niches. Exp Cell Res. doi: 10.1016/j.yexcr.2013.02.012
    • (2013) Exp Cell Res
    • Irmisch, A.1    Huelsken, J.2
  • 89
    • 84926251200 scopus 로고    scopus 로고
    • Outsmart tumor exosomes to steal the cancer initiating cell its niche
    • Thuma F, Zöller M (2014) Outsmart tumor exosomes to steal the cancer initiating cell its niche. Semin Cancer Biol. doi: 10.1016/j.semcancer.2014.02.011
    • (2014) Semin Cancer Biol
    • Thuma, F.1    Zöller, M.2
  • 91
    • 84901479010 scopus 로고    scopus 로고
    • The role of peroxiredoxin II in chemoresistance of breast cancer cells
    • 4041024 24976757
    • Wang T, Diaz AJ, Yen Y (2014) The role of peroxiredoxin II in chemoresistance of breast cancer cells. Breast Cancer 6:73-80
    • (2014) Breast Cancer , vol.6 , pp. 73-80
    • Wang, T.1    Diaz, A.J.2    Yen, Y.3
  • 93
    • 84870911785 scopus 로고    scopus 로고
    • Docetaxel-resistance in prostate cancer: Evaluating associated phenotypic changes and potential for resistance transfer via exosomes
    • 1:CAS:528:DC%2BC38XhvFSks73N 3519481 23251413
    • Corcoran C, Rani S, O'Brien K, O'Neill A, Prencipe M, Sheikh R, Webb G, McDermott R, Watson W, Crown J, O'Driscoll L (2012) Docetaxel-resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes. PLoS One 7(12):e50999
    • (2012) PLoS One , vol.7 , Issue.12 , pp. 50999
    • Corcoran, C.1    Rani, S.2    O'Brien, K.3    O'Neill, A.4    Prencipe, M.5    Sheikh, R.6    Webb, G.7    McDermott, R.8    Watson, W.9    Crown, J.10    O'Driscoll, L.11
  • 94
    • 27644524811 scopus 로고    scopus 로고
    • Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
    • 1:CAS:528:DC%2BD2MXhtFWhtLnK 16227410
    • Safaei R, Larson BJ, Cheng TC, Gibson MA, Otani S, Naerdemann W, Howell SB (2005) Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells. Mol Cancer Ther 4(10):1595-1604
    • (2005) Mol Cancer Ther , vol.4 , Issue.10 , pp. 1595-1604
    • Safaei, R.1    Larson, B.J.2    Cheng, T.C.3    Gibson, M.A.4    Otani, S.5    Naerdemann, W.6    Howell, S.B.7
  • 98
    • 79551610187 scopus 로고    scopus 로고
    • Exosomes in the ascites of ovarian cancer patients: Origin and effects on anti-tumor immunity
    • 1:CAS:528:DC%2BC3MXjvVWgtLk%3D 21181093
    • Peng P, Yan Y, Keng S (2011) Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity. Oncol Rep 25:749-762
    • (2011) Oncol Rep , vol.25 , pp. 749-762
    • Peng, P.1    Yan, Y.2    Keng, S.3
  • 103
    • 33845618038 scopus 로고    scopus 로고
    • Association of citrullinated proteins with synovial exosomes
    • 1:CAS:528:DC%2BD2sXktlamsw%3D%3D 17133577
    • Skriner K, Adolph K, Jungblut PR, Burmester GR (2006) Association of citrullinated proteins with synovial exosomes. Arthritis Rheum 54:3809-3814
    • (2006) Arthritis Rheum , vol.54 , pp. 3809-3814
    • Skriner, K.1    Adolph, K.2    Jungblut, P.R.3    Burmester, G.R.4
  • 104
    • 84884585784 scopus 로고    scopus 로고
    • Exosomes: The future of biomarkers in medicine
    • 1:CAS:528:DC%2BC3sXhsVCrtbzO 24044569
    • Properzi F, Logozzi M, Fais S (2013) Exosomes: the future of biomarkers in medicine. Biomark Med 7:769-778
    • (2013) Biomark Med , vol.7 , pp. 769-778
    • Properzi, F.1    Logozzi, M.2    Fais, S.3
  • 106
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • 1:CAS:528:DC%2BD1cXnvVOlu74%3D 18589210
    • Taylor DD, Gercel-Taylor C (2008) MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol 110(1):13-21
    • (2008) Gynecol Oncol , vol.110 , Issue.1 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 107
    • 84884585784 scopus 로고    scopus 로고
    • Exosomes: The future of biomarkers in medicine
    • 1:CAS:528:DC%2BC3sXhsVCrtbzO 24044569
    • Properzi F, Logozzi M, Fais S (2013) Exosomes: the future of biomarkers in medicine. Biomark Med 7(5):769-778
    • (2013) Biomark Med , vol.7 , Issue.5 , pp. 769-778
    • Properzi, F.1    Logozzi, M.2    Fais, S.3
  • 109
    • 67349142591 scopus 로고    scopus 로고
    • Prostate cancer-derived urine exosomes: A novel approach to biomarkers for prostate cancer
    • 1:CAS:528:DC%2BD1MXlslCht70%3D 2696767 19401683
    • Nilsson J, Skog J, Nordstrand A, Baranov V, Mincheva-Nilsson L, Breakefield XO, Widmark A (2009) Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer. Br J Cancer 100(10):1603-1607
    • (2009) Br J Cancer , vol.100 , Issue.10 , pp. 1603-1607
    • Nilsson, J.1    Skog, J.2    Nordstrand, A.3    Baranov, V.4    Mincheva-Nilsson, L.5    Breakefield, X.O.6    Widmark, A.7
  • 111
    • 78650966289 scopus 로고    scopus 로고
    • Intracellular and extracellular microRNAs in breast cancer
    • 1:CAS:528:DC%2BC3MXitFSlu7w%3D 21059829
    • Corcoran C, Friel AM, Duffy MJ, Crown J, O'Driscoll L (2011) Intracellular and extracellular microRNAs in breast cancer. Clin Chem 57(1):18-32
    • (2011) Clin Chem , vol.57 , Issue.1 , pp. 18-32
    • Corcoran, C.1    Friel, A.M.2    Duffy, M.J.3    Crown, J.4    O'Driscoll, L.5
  • 112
    • 77957091969 scopus 로고    scopus 로고
    • Circulating microRNA in body fluid: A new potential biomarker for cancer diagnosis and prognosis
    • 1:CAS:528:DC%2BC3cXhtlegtrjJ 20624164
    • Kosaka N, Iguchi H, Ochiya T (2010) Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis. Cancer Sci 101(10):2087-2092
    • (2010) Cancer Sci , vol.101 , Issue.10 , pp. 2087-2092
    • Kosaka, N.1    Iguchi, H.2    Ochiya, T.3
  • 114
    • 38449119776 scopus 로고    scopus 로고
    • Novel exosome-targeted CD4 + T cell vaccine counteracting CD4 + 25 + regulatory T cell-mediated immune suppression and stimulating efficient central memory CD8 + CTL response
    • 1:CAS:528:DC%2BD2sXpt1Smsr4%3D 2567870 17709486
    • Hao S, Liu Y, Yuan J, Zhang X, He T, Wu X, Wei Y, Sun D, Xiang J (2007) Novel exosome-targeted CD4 + T cell vaccine counteracting CD4 + 25 + regulatory T cell-mediated immune suppression and stimulating efficient central memory CD8 + CTL response. J Immunol 179:2731-2740
    • (2007) J Immunol , vol.179 , pp. 2731-2740
    • Hao, S.1    Liu, Y.2    Yuan, J.3    Zhang, X.4    He, T.5    Wu, X.6    Wei, Y.7    Sun, D.8    Xiang, J.9
  • 115
    • 41149172340 scopus 로고    scopus 로고
    • Phase i clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
    • 1:CAS:528:DC%2BD1cXjslCnsbk%3D 18362931
    • Dai S, Wei D, Wu Z, Zhou X, Wei X, Huang H, Li G (2008) Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer. Mol Ther 16:782-790
    • (2008) Mol Ther , vol.16 , pp. 782-790
    • Dai, S.1    Wei, D.2    Wu, Z.3    Zhou, X.4    Wei, X.5    Huang, H.6    Li, G.7
  • 118
    • 84906098610 scopus 로고    scopus 로고
    • Dendritic cell-derived exosomes as immunotherapies in the fight against cancer
    • 1:CAS:528:DC%2BC2cXhtFyqs77N 25049431
    • Pitt JM, Charrier M, Viaud S, André F, Besse B, Chaput N, Zitvogel L (2014) Dendritic cell-derived exosomes as immunotherapies in the fight against cancer. J Immunol 193:1006-1011
    • (2014) J Immunol , vol.193 , pp. 1006-1011
    • Pitt, J.M.1    Charrier, M.2    Viaud, S.3    André, F.4    Besse, B.5    Chaput, N.6    Zitvogel, L.7
  • 120
    • 84878629272 scopus 로고    scopus 로고
    • Proteomics, transcriptomics and lipidomics of exosomes and ectosomes
    • 1:CAS:528:DC%2BC3sXjslajt7Y%3D 23401200
    • Choi DS, Kim DK, Kim YK, Gho YS (2013) Proteomics, transcriptomics and lipidomics of exosomes and ectosomes. Proteomics 13(10-11):1554-1571
    • (2013) Proteomics , vol.13 , Issue.10-11 , pp. 1554-1571
    • Choi, D.S.1    Kim, D.K.2    Kim, Y.K.3    Gho, Y.S.4
  • 123
    • 84906700936 scopus 로고    scopus 로고
    • Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
    • 1:CAS:528:DC%2BC2cXhtFygsLjI 4161194 25099143
    • He M, Crow J, Roth M, Zeng Y, Godwin AK (2014) Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology. Lab Chip 14(19):3773-3780
    • (2014) Lab Chip , vol.14 , Issue.19 , pp. 3773-3780
    • He, M.1    Crow, J.2    Roth, M.3    Zeng, Y.4    Godwin, A.K.5
  • 124
    • 84914153712 scopus 로고    scopus 로고
    • A review of exosome separation techniques and characterization of B16-F10 mouse melanoma exosomes with AF4-UV-MALS-DLS-TEM
    • [Epub ahead of print]
    • Petersen KE, Manangon E, Hood JL, Wickline SA, Fernandez DP, Johnson WP, Gale BK (2014) A review of exosome separation techniques and characterization of B16-F10 mouse melanoma exosomes with AF4-UV-MALS-DLS-TEM. Anal Bioanal Chem [Epub ahead of print]
    • (2014) Anal Bioanal Chem
    • Petersen, K.E.1    Manangon, E.2    Hood, J.L.3    Wickline, S.A.4    Fernandez, D.P.5    Johnson, W.P.6    Gale, B.K.7
  • 126
    • 0016609349 scopus 로고
    • The separation and characterization of liver plasma membrane fragments circulating in the blood of patients with cholestasis
    • 1126024
    • De Broe ME, Borgers M, Wieme RJ (1975) The separation and characterization of liver plasma membrane fragments circulating in the blood of patients with cholestasis. Clin Chim Acta 59(3):369-372
    • (1975) Clin Chim Acta , vol.59 , Issue.3 , pp. 369-372
    • De Broe, M.E.1    Borgers, M.2    Wieme, R.J.3
  • 127
    • 0018089964 scopus 로고
    • The incidence and likely origins of serum particulate alkaline phosphatase and lipoprotein-X in liver disease
    • 1:CAS:528:DyaE1cXlvFGjsLY%3D 699340
    • Brocklehurst D, Wilde CE, Doar JW (1978) The incidence and likely origins of serum particulate alkaline phosphatase and lipoprotein-X in liver disease. Clin Chim Acta 88(3):509-515
    • (1978) Clin Chim Acta , vol.88 , Issue.3 , pp. 509-515
    • Brocklehurst, D.1    Wilde, C.E.2    Doar, J.W.3
  • 128
    • 0020511115 scopus 로고
    • Transferrin recycling in reticulocytes: PH and iron are important determinants of ligand binding and processing
    • 1:CAS:528:DyaL3sXktlKmtrk%3D 6870878
    • Harding C, Stahl P (1983) Transferrin recycling in reticulocytes: pH and iron are important determinants of ligand binding and processing. Biochem Biophys Res Commun 113(2):650-658
    • (1983) Biochem Biophys Res Commun , vol.113 , Issue.2 , pp. 650-658
    • Harding, C.1    Stahl, P.2
  • 129
    • 0020956787 scopus 로고
    • Fate of the transferrin receptor during maturation of sheep reticulocyte in vitro: Selective externalization of the receptor
    • 1:CAS:528:DyaL3sXltF2rurk%3D 6307529
    • Pan BT, Johnstone RM (1983) Fate of the transferrin receptor during maturation of sheep reticulocyte in vitro: selective externalization of the receptor. Cell 33(3):967-978
    • (1983) Cell , vol.33 , Issue.3 , pp. 967-978
    • Pan, B.T.1    Johnstone, R.M.2
  • 130
    • 0023645106 scopus 로고
    • Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
    • 1:CAS:528:DyaL2sXksFKmsbo%3D 3597417
    • Johnstone RM, Adam M, Hammond JR, Orr L, Turbide C (1987) Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem 262(19):9412-9420
    • (1987) J Biol Chem , vol.262 , Issue.19 , pp. 9412-9420
    • Johnstone, R.M.1    Adam, M.2    Hammond, J.R.3    Orr, L.4    Turbide, C.5
  • 131
    • 84874354368 scopus 로고    scopus 로고
    • Exosomes: Looking back three decades and into the future
    • 1:CAS:528:DC%2BC3sXjtFCnsbg%3D 3575527 23420870
    • Harding CV, Heuser JE, Stahl PD (2013) Exosomes: looking back three decades and into the future. J Cell Biol 200(4):367-371
    • (2013) J Cell Biol , vol.200 , Issue.4 , pp. 367-371
    • Harding, C.V.1    Heuser, J.E.2    Stahl, P.D.3
  • 132
    • 0025890156 scopus 로고
    • Exosome formation during maturation of mammalian and avian reticulocytes: Evidence that exosome release is a major route for externalization of obsolete membrane proteins
    • 1:CAS:528:DyaK3MXks12iurg%3D 2037622
    • Johnstone RM, Matthew A, Mason AB, Teng K (1991) Exosome formation during maturation of mammalian and avian reticulocytes: evidence that exosome release is a major route for externalization of obsolete membrane proteins. J Cell Physiol 147:27-36
    • (1991) J Cell Physiol , vol.147 , pp. 27-36
    • Johnstone, R.M.1    Matthew, A.2    Mason, A.B.3    Teng, K.4
  • 133
    • 0035490884 scopus 로고    scopus 로고
    • The endocytic pathway: A mosaic of domains
    • 1:CAS:528:DC%2BD3MXnvVajs7s%3D 11584299
    • Gruenberg J (2001) The endocytic pathway: a mosaic of domains. Nat Rev Mol Cell Biol 2:721-730
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 721-730
    • Gruenberg, J.1
  • 135
    • 33747616431 scopus 로고    scopus 로고
    • Membrane-derived microvesicles: Important and underappreciated mediators of cell-to-cell communication
    • 1:CAS:528:DC%2BD28XosVSjsrk%3D 16791265
    • Ratajczak J, Wysoczynski M, Hayek F, Janowska-Wieczorek A, Ratajczak MZ (2006) Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia 20:1487-1495
    • (2006) Leukemia , vol.20 , pp. 1487-1495
    • Ratajczak, J.1    Wysoczynski, M.2    Hayek, F.3    Janowska-Wieczorek, A.4    Ratajczak, M.Z.5
  • 136
    • 79960096964 scopus 로고    scopus 로고
    • Exosomes: Secreted vesicles and intercellular communications
    • 3155154 21876726
    • Théry C (2011) Exosomes: secreted vesicles and intercellular communications. F1000 Biol Rep 3:15
    • (2011) F1000 Biol Rep , vol.3 , pp. 15
    • Théry, C.1
  • 137
    • 84949934993 scopus 로고    scopus 로고
    • As we wait: Coping with an imperfect nomenclature for extracellular vesicles
    • Gould SJ, Raposo G (2013) As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles. doi: 10.3402/jev.v2i0.20389
    • (2013) J Extracell Vesicles
    • Gould, S.J.1    Raposo, G.2
  • 138
    • 77952704204 scopus 로고    scopus 로고
    • Flow cytometric analysis of circulating microparticles in plasma
    • 2919894 20235276
    • Orozco AF, Lewis DE (2010) Flow cytometric analysis of circulating microparticles in plasma. Cytometry 77:502-514
    • (2010) Cytometry , vol.77 , pp. 502-514
    • Orozco, A.F.1    Lewis, D.E.2
  • 140
    • 0842277810 scopus 로고    scopus 로고
    • Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: A mechanism for generation of soluble cytokine receptors
    • 1:CAS:528:DC%2BD2cXhtlWjtLk%3D 337047 14745008
    • Hawari FI, Rouhani FN, Cui X, Yu ZX, Buckley C, Kaler M, Levine SJ (2004) Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors. Proc Natl Acad Sci USA 101:1297-1302
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1297-1302
    • Hawari, F.I.1    Rouhani, F.N.2    Cui, X.3    Yu, Z.X.4    Buckley, C.5    Kaler, M.6    Levine, S.J.7
  • 141
    • 0032493658 scopus 로고    scopus 로고
    • Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
    • 1:CAS:528:DyaK1cXlsVWgsbs%3D 9685355
    • Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ (1998) Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J Biol Chem 273:20121-20127
    • (1998) J Biol Chem , vol.273 , pp. 20121-20127
    • Escola, J.M.1    Kleijmeer, M.J.2    Stoorvogel, W.3    Griffith, J.M.4    Yoshie, O.5    Geuze, H.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.