Investigating herb-herb interactions: The potential attenuated toxicity mechanism of the combined use of Glycyrrhizae radix et rhizoma (Gancao) and Sophorae flavescentis radix (Kushen)

Journal of Ethnopharmacology

Volumn 165, Issue , 2015, Pages 243-250

  Shi, Lei ^a   Tang, Xiuling ^a   Dang, Xueliang ^a   Wang, Qinhui ^a   Wang, Xiangrui ^b   He, Ping ^b   Wang, Qingwei ^a   Liu, Linna ^a   Liu, Xinyou ^a   Zhang, Yan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Attenuatedt oxicity; Glycyrrhizaeradixet rhizome; Herbherb interactions; Sophorae flavescentisradix

Indexed keywords

GLYCYRRHETINIC ACID; GLYCYRRHIZA EXTRACT; GLYCYRRHIZIC ACID; MATRINE; OXYMATRINE; PLANT EXTRACT; SOPHORAE FLAVESCENTIS EXTRACT; UNCLASSIFIED DRUG; HERBACEOUS AGENT; KUSHEN;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; GLYCYRRHIZA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEDICINAL PLANT; NONHUMAN; PHYTOTOXICITY; RAT; SOPHORAE FLAVESCENTIS; TIME TO MAXIMUM PLASMA CONCENTRATION; VOLUME OF DISTRIBUTION; ANIMAL; CHEMISTRY; DRUG INTERACTION; MALE; SOPHORA; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; GLYCYRRHIZA; MALE; MASS SPECTROMETRY; RATS; RATS, SPRAGUE-DAWLEY; SOPHORA;

EID: 84925455195     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.02.022     Document Type: Article

References (32)

1. T. Akao, M. Hattori, M. Kanaoka, K. Yamamoto, T. Namba, and K. Kobashi Hydrolysis of glycyrrhizin to 18 beta-glycyrrhetylmonoglucuronide by lysosomalbeta-d-glucuronidase of animal livers Biochemical Pharmacology 41 1991 1025 1029
2. China Academy of Chinese Medical Sciences Journal of Shaanxi Traditional Chinese Medicine 1962
3. Committee of the Pharmacopoeia of PR China Pharmacopoeia of PR China Part I 2010 China Medical Science Press 285 286 127-128
4. Editorial Board of Handbook of Ningxia Chinese Herbal Medicine Handbook of Ningxia Chinese Herbal Medicine 1971 Ningxia Peoples Publishing House Ningxia, China
5. Y. Fu, J. Chen, Y.J. Li, Y.F. Zheng, and P. Li Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice Food Chemistry 141 2013 1063 1071
6. Y. Kageyama, H. Suzuki, and T. Saruta Renin-dependency of glycyrrhizin induced pseudoaldosteronism Endocrinologia Japonica 38 1991 103 108
7. S. Krähenbühl, F. Hasler, and R. Krapf Analysis and pharmacokinetics of glycyrrhizic acid and glycyrrhetinic acid in humans and experimental animals Steroids 59 1994 121 126
8. D.V. Kratschmar, A. Vuorinen, T. Da, Cunha, G. Wolber, D. Classen-Houben, O. Doblhoff, D. Schuster, and A. Odermatt Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11β-hydroxysteroid dehydrogenase type 2 Journal of Steroid Biochemistry and Molecular Biology 125 2011 129 142
9. G. Kusano, M. Shibano, and H. Watanabe Pharmaceutical botanical studies on some Glycyrrhiza species Yakugaku Zasshi 123 2003 619 631
10. J.Y. Lee, J.H. Lee, J.H. Park, S.Y. Kim, J.Y. Choi, S.H. Lee, Y.S. Kim, S.S. Kang, E.C. Jang, and Y. Han Liquiritigenin, a licorice flavonoid, helps mice resist disseminated candidiasis due to Candida albicans by Th1 immune response, whereas liquiritin, its glycoside form, does not International Immunopharmacology 9 2009 632 638
11. J.H. Li, H.Y. Li, and H.B. Li Clinical treatment of 30 cases of peptic ulcer with Gancao decoction and Kushen decoction Journal of Practical Medicine Department of Internal Medicine 2 2010 23 25
12. Y. Lin Clinical treatment of 32 cases of Behcets disease with Gancao decoction and Kushen decoction Modern Traditional Chinese Medicine 31 2011 21 22
13. K.L. Miao, J.Z. Zhang, Y. Dong, and Y.F. Xi Research progress on the chemical compounds and pharmacology of Sophora flavescens Natural Product Research Development 13 2001 69 73
14. N. Ohtake, A. Kido, K. Kubota, N. Tsuchiya, T. Morita, Y. Kase, and S. Takeda A possible involvement of 3-monoglucuronyl-glycyrrhetinic acid, a metabolite of glycyrrhizin (GL), in GL-induced pseudoaldosteronism Life Sciences 80 2007 1545 1552
15. Y.W. Shin, A.E. Bae, B. Lee, J.A. Kim, Y.S. Kin, and D.H. Kim In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components Planta Medica 73 2007 257 261
16. S. Shintani, H. Murase, H. Tsukagoshi, and T. Shiigai Glycyrrhizin (licorice)-induced hypokalemic myopathy. Report of 2 cases and review of the literature European Neurology 32 1992 44 51
17. T. Tanahashi, T. Mune, H. Morita, H. Tanahashi, Y. Isomura, T. Suwa, H. Daido, C.E. Gomez-Sanchez, and K. Yasuda Glycyrrhizic acid suppresses type 2 11β-hydroxysteroid dehydrogenase expression in vivo Journal of Steroid Biochemistry and Molecular Biology 80 2002 441 447
18. L. Tang, L.N. Dong, X.J. Peng, Y. Li, J. Shi, F.Y. Zhou, and Z.Q. Liu Pharmacokinetic characterization of oxymatrine and matrine in rats after oral administration of radix Sophoraetonkinensis extract and oxymatrine by sensitive and robust UPLC-MS/MS method Journal of Pharmaceutical and Biomedical Analysis 83 2013 179 185
19. Y.F. Ueng, C.C. Chen, C.C. Tsai, and P. Soucek Differential inductive profiles of hepatic cytochrome P450s by the extracts of Sophora flavescens in male and female C57BL/6JNarl mice Journal of Ethnopharmacology 126 2009 437 446
20. T.G. Van Rossum, F.H. de Jong, W.C. Hop, F. Boomsma, and S.W. Schalm Pseudo-aldosteronism'induced by intravenous glycyrrhizin treatment of chronic hepatitis C patients Journal of Gastroenterology and Hepatology 16 2001 789 795
21. H. Wagner Appendix: Quality proof of herbal drugs from Traditional Chinese Medicine (TCM drugs) A Materia Medica for Chinese Medicine 2009 993 1004
22. X.Y. Wan, M. Luo, X.D. Li, and P. He Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine Chemico-biological Interactions 181 2009 15 19
23. J.H. Wang Traditional Chinese medicine and the positive correlation with homeostatic evolution of human being: based on medical perspective Chinese Journal of Integrative Medicine 18 2012 629 634
24. Q.H. Wang, L. Shi, X.L. Tang, Q.W. Wang, X.L. Dang, and Y. Zhang Pharmacokinetic study of multiple active constituents from Kushen-Gancao Decoction after oral administration in rat by HPLC-MS/MS Journal of Chromatography B 965 2014 19 26
25. S. Wang, Y. Hu, W. Tan, X. Wu, R. Chen, J. Cao, M. Chen, and Y. Wang Compatibility art of traditional Chinese medicine: from the perspective of herb pairs Journal of Ethnopharmacology 143 2012 412 423
26. C.H. Xu, P. Wang, Y. Wang, Y.a.n. Yang, D.H. Li, H.F. Li, S.Q. Sun, and X.Z. Wu Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid Journal of Ethnopharmacology 149 2013 443 452
27. W. Xu Clinical observation on the treatment of 31 cases of viral cholestatic hepatitis with Kushen decoction Journal of Zhejiang College of Traditional Chinese Medicine 21 1997 51 52
28. W. Xu, H. Lin, Y. Zhang, X. Chen, B. Hua, W. Hou, X. Qi, Y. Pei, X. Zhu, Z. Zhao, and L. Yang Compound Kushen injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway Journal of Experimental & Clinical Cancer Research 28 2011 103
29. Z. Yang, S. Gao, T. Yin, K.H. Kulkarni, Y. Teng, M. You, and M. Hu Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method Journal of Pharmaceutical and Biomedical Analysis 51 2010 1120 1127
30. J. Zhao, X.Y. Wan, M. Luo, T.S. Chen, and P. He Antifibrotic effects of glycyrrhizin and matrine in vitro and in vivo Biomedicine & Preventive Nutrition 2 2012 132 137
31. X.Y. Zhi Traditional Chinese medicine diagnosis and treatment of type 2 diabetes in Tianjin urban population Zhong Xi Yi Jie He Xue Bao 7 2009 823 826
32. S.K. Zhou, R.L. Zhang, Y.F. Xu, and T.N. Bi Antioxidant and immunity activities of Fufang Kushen injection liquid Molecules 17 2012 6481 6490