Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: Competing mechanisms between paeoniflorin and glycyrrhetinic acid

Journal of Ethnopharmacology

Volumn 149, Issue 2, 2013, Pages 443-452

  Xu, Chang Hua ^a   Wang, Ping ^c   Wang, Yang ^b   Yang, Yan ^c   Li, Dong Hua ^d   Li, Hui Fen ^e   Sun, Su Qin ^a   Wu, Xian Zhong ^d  

^a TSINGHUA UNIVERSITY   (China)

^b FIRST TEACHING HOSPITAL OF TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d Tianjin Institute of Acute Abdominal Diseases of Integrated Traditional and Western Medicine   (China)

^e TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Glycyrrhetinic acid; Glycyrrhizae uralensis; HPLC MS MS; Paeoniflorin; Radix Paeoniae Alba; Shaoyao Gancao Decoction

Indexed keywords

ALBIFLORIN; BETA GLUCOSIDASE; FLAVONOID; GLYCOSIDE; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; HERBACEOUS AGENT; ISOLIQUIRITIGENIN; ISOLIQUIRITIN; LIQUIRITIN; LIQUITIRIGENIN; ONONIN; OXYPAEONIFLORIN; PAEONIFLORIN; SHAOYAO GANCAO DECOCTION; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHINESE MEDICINE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MIXTURE; DRUG STRUCTURE; GLYCYRRHIZAE URALENSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PRECIPITATION; RADIX PAEONIAE ALBA; RAT; STATISTICAL SIGNIFICANCE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; WISTAR RAT;

GLYCYRRHIZA URALENSIS; PAEONIA LACTIFLORA; RATTUS; RATTUS NORVEGICUS;

GA; GLYCYRRHENITIC ACID; GLYCYRRHETINIC ACID; GLYCYRRHIZAE URALENSIS; GLYCYRRHIZIN; GU; GZ; HERBAL MEDICINE; HM; HPLC-MS/MS; PAEONIFLORIN; PF; RADIX PAEONIAE ALBA; RP; SGD; SHAOYAO-GANCAO DECOCTION;

ANALGESICS; ANIMALS; BIOLOGICAL AVAILABILITY; DRUGS, CHINESE HERBAL; FLAVANONES; GLUCOSIDES; HERB-DRUG INTERACTIONS; MALE; PARASYMPATHOLYTICS; PENTACYCLIC TRITERPENES; RATS; RATS, WISTAR;

EID: 84883191146     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.06.049     Document Type: Article

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