A study evaluating the bidirectional relationship between inflammatory bowel disease and self-reported non-celiac gluten sensitivity

Inflammatory Bowel Diseases

Volumn 21, Issue 4, 2015, Pages 847-853

  Aziz, Imran ^a   Branchi, Federica ^a,b   Pearson, Katherine ^a   Priest, Josephine ^a   Sanders, David S ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

celiac disease; Crohn's disease; gluten free diet; inflammatory bowel disease; non celiac gluten sensitivity; ulcerative colitis

Indexed keywords

ABDOMINAL DISCOMFORT; ABDOMINAL PAIN; ADULT; ARTHRALGIA; ARTICLE; BLOATING; CONSTIPATION; CONTROLLED STUDY; CROHN DISEASE; CROHN DISEASE ACTIVITY INDEX; CROSS-SECTIONAL STUDY; DIARRHEA; DISEASE SEVERITY; DYSPEPSIA; ERUCTATION; FATIGUE; FEMALE; FLATULENCE; GLUTEN FREE DIET; HEADACHE; HUMAN; INFLAMMATORY BOWEL DISEASE; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NAUSEA; NUTRITIONAL INTOLERANCE; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; SELF REPORT; SELF REPORTED NON CELIAC GLUTEN SENSITIVITY; ULCERATIVE COLITIS; AGED; CELIAC DISEASE; COLITIS, ULCERATIVE; COMPLICATION; INFLAMMATORY BOWEL DISEASES; IRRITABLE BOWEL SYNDROME; SEVERITY OF ILLNESS INDEX; UTILIZATION;

GLUTEN;

ADULT; AGED; CELIAC DISEASE; COLITIS, ULCERATIVE; CROHN DISEASE; CROSS-SECTIONAL STUDIES; DIET, GLUTEN-FREE; DYSPEPSIA; FEMALE; GLUTENS; HUMANS; INFLAMMATORY BOWEL DISEASES; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; PREVALENCE; SELF REPORT; SEVERITY OF ILLNESS INDEX; SURVEYS AND QUESTIONNAIRES;

EID: 84925425732     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000335     Document Type: Article

References (48)

1. Sapone A, Bai JC, Ciacci C, et al. Spectrum of gluten-related disorders. Consensus on new nomenclature and classification. BMC Med. 2012;10:13.
2. Ludvigsson JF, Leffler DA, Bai JC, et al. The Oslo definitions for coeliac disease and related terms. Gut. 2013;62:43-52.
3. Catassi C, Bai JC, Bonaz B, et al. Non-celiac gluten sensitivity: the new frontier of gluten related disorders. Nutrients. 2013;5:3839-3853.
4. Rubio-Tapia A, Ludvigsson JF, Brantner TL, et al. The prevalence of celiac disease in the United States. Am J Gastroenterol. 2012;107: 1538-1544; quiz 1537, 1545.
5. Tanpowpong P, Ingham TR, Lampshire PK, et al. Coeliac disease and gluten avoidance in New Zealand children. Arch Dis Child. 2012;97: 12-16.
6. Aziz I, Lewis NR, Hadjivassiliou M, et al. A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care. Eur J Gastroenterol Hepatol. 2014;26: 33-39.
7. Volta U, De Giorgio R. New understanding of gluten sensitivity. Nat Rev Gastroenterol Hepatol. 2012;9:295-299.
8. Biesiekierski JR, Newnham ED, Irving PM, et al. Gluten causes gastrointestinal symptoms in subjects without celiac disease. A double-blind randomized placebo-controlled trial. Am J Gastroenterol. 2011;106: 508-514; quiz 515.
9. Peters SL, Biesiekierski JR, Yelland GW, et al. Randomised clinical trial: gluten may cause depression in subjects with non-coeliac gluten sensitivity-an exploratory randomised clinical study. Aliment Pharmacol Ther. 2014;39:1104-1112.
10. Verdu EF, Armstrong D, Murray JA. Between celiac disease and irritable bowel syndrome: the "no man's land" of gluten sensitivity. Am J Gastroenterol. 2009;104:1587-1594.
11. Wahnschaffe U, Schulzke JD, Zeitz M, et al. Predictors of clinical response to gluten-free diet in patients diagnosed with diarrheapredominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 2007;5:844-850; quiz 769.
12. Vazquez-Roque MI, Camilleri M, Smyrk T, et al. A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function. Gastroenterology. 2013;144: 903-911.e3.
13. Herfarth HH, Martin CF, Sandler RS, et al. Prevalence of a gluten-free diet and improvement of clinical symptoms in patients with inflammatory bowel diseases. Inflamm Bowel Dis. 2014;20:1194-1197.
14. Sanders DS, Patel D, Stephenson TJ, et al. A primary care cross-sectional study of undiagnosed adult coeliac disease. Eur J Gastroenterol Hepatol. 2003;15:407-413.
15. Best WR, Becktel JM, Singleton JW, et al. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology. 1976;70:439-444.
16. Walmsley RS, Ayres RC, Pounder RE, et al. A simple clinical colitis activity index. Gut. 1998;43:29-32.
17. Jowett SL, Seal CJ, Phillips E, et al. Defining relapse of ulcerative colitis using a symptom-based activity index. Scand J Gastroenterol. 2003;38:164-171.
18. Chapman-Kiddell CA, Davies PS, Gillen L, et al. Role of diet in the development of inflammatory bowel disease. Inflamm Bowel Dis. 2010; 16:137-151.
19. Loftus EV. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology. 2004; 126:1504-1517.
20. Hou JK, Abraham B, El-Serag H. Dietary intake and risk of developing inflammatory bowel disease. A systematic review of the literature. Am J Gastroenterol. 2011;106:563-573.
21. Zallot C, Quilliot D, Chevaux JB, et al. Dietary beliefs and behavior among inflammatory bowel disease patients. Inflamm Bowel Dis. 2013; 19:66-72.
22. Cohen AB, Lee D, Long MD, et al. Dietary patterns and self-reported associations of diet with symptoms of inflammatory bowel disease. Dig Dis Sci. 2013;58:1322-1328.
23. Ballegaard M, Bjergstrøm A, Brøndum S, et al. Self-reported food intolerance in chronic inflammatory bowel disease. Scand J Gastroenterol. 1997;32:569-571.
24. Rajendran N, Kumar D. Role of diet in the management of inflammatory bowel disease. World J Gastroenterol. 2010;16:1442-1448.
25. Cabré E, Domènech E. Impact of environmental and dietary factors on the course of inflammatory bowel disease. World J Gastroenterol. 2012;18: 3814-3822.
26. Sapone A, Lammers KM, Mazzarella G, et al. Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease. Int Arch Allergy Immunol. 2010;152:75-80.
27. Sapone A, Lammers KM, Casolaro V, et al. Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions. Celiac disease and gluten sensitivity. BMC Med. 2011;9:23.
28. Brottveit M, Beitnes AC, Tollefsen S, et al. Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity. Am J Gastroenterol. 2013;108:842-850.
29. Carroccio A, Mansueto P, Iacono G, et al. Non-celiac wheat sensitivity diagnosed by double-blind placebo-controlled challenge: exploring a new clinical entity. Am J Gastroenterol. 2012;107:1898-1906; quiz 1907.
30. Volta U, Tovoli F, Cicola R, et al. Serological tests in gluten sensitivity (nonceliac gluten intolerance). J Clin Gastroenterol. 2012;46:680-685.
31. Konrad A, Rütten C, Flogerzi B, et al. Immune sensitization to yeast antigens in ASCA-positive patients with Crohn's disease. Inflamm Bowel Dis. 2004;10:97-105.
32. Brunner B, Scheurer U, Seibold F. Differences in yeast intolerance between patients with Crohn's disease and ulcerative colitis. Dis Colon Rectum. 2007;50:83-88.
33. Barclay GR, McKenzie H, Pennington J, et al. The effect of dietary yeast on the activity of stable chronic Crohn's disease. Scand J Gastroenterol. 1992;27:196-200.
34. Junker Y, Zeissig S, Kim SJ, et al. Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4. J Exp Med. 2012;209:2395-2408.
35. Tilg H, Koch R, Moschen AR. Proinflammatory wheat attacks on the intestine. Alpha-amylase trypsin inhibitors as new players. Gastroenterology. 2013;144:1561-1563; discussion 1563-1564.
36. Halmos EP, Power VA, Shepherd SJ, et al. A diet low in FODMAPs reduces symptoms of irritable bowel syndrome. Gastroenterology. 2014;146:67-75.e5.
37. Murray K, Wilkinson-Smith V, Hoad C, et al. Differential effects of FODMAPs (fermentable oligo-, di-, mono-saccharides and polyols) on small and large intestinal contents in healthy subjects shown by MRI. Am J Gastroenterol. 2014;109:110-119.
38. Gearry RB, Irving PM, Barrett JS, et al. Reduction of dietary poorly absorbed short-chain carbohydrates (FODMAPs) improves abdominal symptoms in patients with inflammatory bowel disease-a pilot study. J Crohns Colitis. 2009;3:8-14.
39. Carroccio A, Rini G, Mansueto P. Non-celiac wheat sensitivity is a more appropriate label than non-celiac gluten sensitivity. Gastroenterology. 2014;146:320-321.
40. Tavakkoli A, Lewis SK, Tennyson CA, et al. Characteristics of patients who avoid wheat and/or gluten in the absence of Celiac disease. Dig Dis Sci. 2014;59:1255-1261.
41. Walker D, Orchard T. Do extraintestinal manifestations predict disease course, severity, and/or activity in IBD? Inflamm Bowel Dis. 2008;14 (suppl 2):S200-S201.
42. Hadjivassiliou M, Sanders DS, Grünewald RA, et al. Gluten sensitivity: from gut to brain. Lancet Neurol. 2010;9:318-330.
43. Aziz I, Hadjivassiliou M, Sanders DS. Editorial: noncoeliac gluten sensitivity-a disease of the mind or gut? Aliment Pharmacol Ther. 2014;40:113-114.
44. Aziz I, Hadjivassiliou M. Coeliac disease: noncoeliac gluten sensitivity-food for thought. Nat Rev Gastroenterol Hepatol. 2014;11:398-399.
45. Isasi C, Colmenero I, Casco F, et al. Fibromyalgia and non-celiac gluten sensitivity. A description with remission of fibromyalgia. Rheumatol Int. 2014;34:1607-1612.
46. James SL, Christophersen CT, Bird AR, et al. Abnormal fibre usage in UC in remission. Gut . [published online ahead of print July 18, 2014]. DOI: 10.1136/gutjnl-2014-307198.
47. Leeds JS, Höroldt BS, Sidhu R, et al. Is there an association between coeliac disease and inflammatory bowel diseases? A study of relative prevalence in comparison with population controls. Scand J Gastroenterol. 2007;42:1214-1220.
48. Casella G, D'Inc? R, Oliva L, et al. Prevalence of celiac disease in inflammatory bowel diseases. An IG-IBD multicentre study. Dig Liver Dis. 2010; 42:175-178.