HDAC6 Inhibitors modulate lys49 acetylation and membrane localization of -catenin in human ipsc-derived neuronal cells

ACS Chemical Biology

Volumn 10, Issue 3, 2015, Pages 883-890

  Iaconelli, Jonathan ^a,b   Huang, Joanne H ^a,b   Berkovitch, Shaunna S ^a,b   Chattopadhyay, Shrikanta ^b,d   Mazitschek, Ralph ^a,b   Schreiber, Stuart L ^b,e   Haggarty, Stephen J ^a   Karmacharya, Rakesh ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c MCLEAN HOSPITAL   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; CASEIN KINASE I; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; LYSINE; WNT PROTEIN; CTNNB1 PROTEIN, HUMAN; HISTONE DEACETYLASE; ISOENZYME; PROTEASOME;

ARTICLE; CONTROLLED STUDY; HISTONE ACETYLATION; HUMAN; HUMAN CELL; NERVE CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; UBIQUITINATION; ACETYLATION; BINDING SITE; CELL CULTURE; CELL DIFFERENTIATION; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; INDUCED PLURIPOTENT STEM CELL; KINETICS; METABOLISM; PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

ACETYLATION; BETA CATENIN; BINDING SITES; CELL DIFFERENTIATION; CELL MEMBRANE; CELLS, CULTURED; GENE EXPRESSION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; ISOENZYMES; KINETICS; LYSINE; MODELS, MOLECULAR; NEURONS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITINATION;

EID: 84925354445     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500838r     Document Type: Article

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