Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53

Chemico-Biological Interactions

Volumn 232, Issue , 2015, Pages 12-20

  Li, Xin ^a,b   Huang, Jun Ming ^b   Wang, Jian Ning ^c   Xiong, Xi Kun ^b   Yang, Xing Fen ^b   Zou, Fei ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGZHOU CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Cancer; Chrysin; Cisplatin; p53 ERK1 2

Indexed keywords

CASPASE 8; CASPASE 9; CHRYSIN; CISPLATIN; CYTOCHROME C; DEATH RECEPTOR 5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN P53; ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; CASPASE; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; SERINE; TNFRSF21 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOACCUMULATION; CANCER INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; APOPTOSIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HCT116 CELL LINE; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CISPLATIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION REGULATION; HCT116 CELLS; HEP G2 CELLS; HUMANS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TUMOR NECROSIS FACTOR; SERINE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84925292496     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.03.003     Document Type: Article

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