The O-methylation of chrysin markedly improves its intestinal anti-inflammatory properties: Structure-activity relationships of flavones

Biochemical Pharmacology

Volumn 86, Issue 12, 2013, Pages 1739-1746

  During, Alexandrine ^a   Larondelle, Yvan ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Caco 2 cells; Flavones; Intestinal inflammation; O methylation; Pro inflammatory mediators

Indexed keywords

CHRYSIN; CYCLOOXYGENASE 2; DIMETHYL SULFOXIDE; FLAVONE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; TRITON X 100; ANTIINFLAMMATORY AGENT; AUTACOID; FLAVONOID;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; HUMAN; HUMAN CELL; IC 50; METHYLATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CACO 2 CELL LINE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; INTESTINE; METABOLISM;

ANTI-INFLAMMATORY AGENTS; CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONES; FLAVONOIDS; HUMANS; INFLAMMATION MEDIATORS; INTESTINES; METHYLATION; NF-KAPPA B; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84888884020     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.10.003     Document Type: Article

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