Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells

Oncology Reports

Volumn 28, Issue 5, 2012, Pages 1719-1726

  Ren, Jie ^a   Cheng, Hong ^a   Xin, Wen Qun ^a   Chen, Xin ^a   Hu, Kun ^a  

^a CHANGZHOU UNIVERSITY   (China)

Author keywords

7 Piperazinethylchrysin; Apoptosis; Caspase 3; HCT 116; Mitochondria; Reactive oxygen species

Indexed keywords

7 PIPERAZINETHYLCHRYSIN; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOCHROME C; FLUOROURACIL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN HCT116; CELL STRUCTURE; CELL VIABILITY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; STRUCTURE ACTIVITY RELATION; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CASPASE INHIBITORS; CELL SURVIVAL; COLORECTAL NEOPLASMS; CYTOCHROMES C; DOWN-REGULATION; FLAVONOIDS; HCT116 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OLIGOPEPTIDES; PIPERAZINES; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84866443277     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2016     Document Type: Article

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