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Volumn 1187, Issue , 2014, Pages 247-254

Identifying direct notch transcriptional targets using the GSI-washout assay

Author keywords

GSI washout; Notch; Signaling; Target identification; Transcription

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CYCLOHEXIMIDE; GAMMA SECRETASE INHIBITOR; NOTCH RECEPTOR; SECRETASE;

EID: 84925285907     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-1139-4_19     Document Type: Review
Times cited : (6)

References (29)
  • 1
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • Iso T, Kedes L, Hamamori Y (2003) HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol 194:237-255
    • (2003) J Cell Physiol , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 2
    • 0034331260 scopus 로고    scopus 로고
    • Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors
    • Leimeister C, Dale K, Fischer A et al (2000) Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. Dev Biol 227:91-103
    • (2000) Dev Biol , vol.227 , pp. 91-10
    • Leimeister, C.1    Dale, K.2    Fischer, A.3
  • 3
    • 0034333446 scopus 로고    scopus 로고
    • Analysis of HeyL expression in wildtype and Notch pathway mutant mouse embryos
    • Leimeister C, Schumacher N, Steidl C et al (2000) Analysis of HeyL expression in wildtype and Notch pathway mutant mouse embryos. Mech Dev 98:175-178
    • (2000) Mech Dev , vol.98 , pp. 175-178
    • Leimeister, C.1    Schumacher, N.2    Steidl, C.3
  • 4
    • 0033166951 scopus 로고    scopus 로고
    • Hey genes: A novel subfamily of hairyand Enhancer of split related genes specifi cally expressed during mouse embryogenesis
    • Leimeister C, Externbrink A, Klamt B et al (1999) Hey genes: a novel subfamily of hairyand Enhancer of split related genes specifi cally expressed during mouse embryogenesis. Mech Dev 85:173-177
    • (1999) Mech Dev , vol.85 , pp. 173-177
    • Leimeister, C.1    Externbrink, A.2    Klamt, B.3
  • 6
    • 79551510137 scopus 로고    scopus 로고
    • Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice
    • Liu Z, Turkoz A, Jackson EN et al (2011) Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice. J Clin Invest 121:800-808
    • (2011) J Clin Invest , vol.121 , pp. 800-808
    • Liu, Z.1    Turkoz, A.2    Jackson, E.N.3
  • 7
    • 0037370310 scopus 로고    scopus 로고
    • Notch1 functions as a tumor suppressor in mouse skin
    • Nicolas M, Wolfer A, Raj K et al (2003) Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 33:416-421
    • (2003) Nat Genet , vol.33 , pp. 416-421
    • Nicolas, M.1    Wolfer, A.2    Raj, K.3
  • 8
    • 0035300448 scopus 로고    scopus 로고
    • Notch signaling induces cell cycle arrest in small cell lung cancer cells
    • 8. Sriuranpong V, Borges MW, Ravi RK et al (2001) Notch signaling induces cell cycle arrest in small cell lung cancer cells. Cancer Res 61:3200-3205
    • (2001) Cancer Res , vol.61 , pp. 3200-3205
    • Sriuranpong, V.1    Borges, M.W.2    Ravi, R.K.3
  • 9
    • 33646671945 scopus 로고    scopus 로고
    • E proteins and Notch signaling cooperate to promote T cell lineage specifi cation and commitment
    • Ikawa T, Kawamoto H, Goldrath AW et al (2006) E proteins and Notch signaling cooperate to promote T cell lineage specifi cation and commitment. J Exp Med 203:1329-1342
    • (2006) J Exp Med , vol.203 , pp. 1329-1342
    • Ikawa, T.1    Kawamoto, H.2    Goldrath, A.W.3
  • 10
    • 0027386233 scopus 로고
    • Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
    • Lieber T, Kidd S, Alcamo E et al (1993) Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev 7:1949-1965
    • (1993) Genes Dev , vol.7 , pp. 1949-1965
    • Lieber, T.1    Kidd, S.2    Alcamo, E.3
  • 11
    • 0029897171 scopus 로고    scopus 로고
    • Subcellular localization of suppressor of hairless in drosophila sense organ cells during Notch signalling
    • Gho M, Lecourtois M, Geraud G et al (1996) Subcellular localization of suppressor of hairless in drosophila sense organ cells during Notch signalling. Development 122:1673-1682
    • (1996) Development , vol.122 , pp. 1673-1682
    • Gho, M.1    Lecourtois, M.2    Geraud, G.3
  • 12
    • 0028973380 scopus 로고
    • Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity
    • Bailey AM, Posakony JW (1995) Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity. Genes Dev 9:2609-2622
    • (1995) Genes Dev , vol.9 , pp. 2609-2622
    • Bailey, A.M.1    Posakony, J.W.2
  • 13
    • 0030044345 scopus 로고    scopus 로고
    • Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
    • Heitzler P, Bourouis M, Ruel L et al (1996) Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 122:161-171
    • (1996) Development , vol.122 , pp. 161-171
    • Heitzler, P.1    Bourouis, M.2    Ruel, L.3
  • 14
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ (1999) Notch signaling: cell fate control and signal integration in development. Science 284:770-776
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 15
    • 80052569569 scopus 로고    scopus 로고
    • Genomewide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells
    • Wang H, Zou J, Zhao B et al (2011) Genomewide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci USA 108: 14908-14913
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 14908-14913
    • Wang, H.1    Zou, J.2    Zhao, B.3
  • 16
    • 0033780472 scopus 로고    scopus 로고
    • Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1
    • Esler WP, Kimberly WT, Ostaszewski BL et al (2000) Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1. Nat Cell Biol 2:428-434
    • (2000) Nat Cell Biol , vol.2 , pp. 428-434
    • Esler, W.P.1    Kimberly, W.T.2    Ostaszewski, B.L.3
  • 17
    • 0033779635 scopus 로고    scopus 로고
    • Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1
    • Zhang Z, Nadeau P, Song W et al (2000) Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nat Cell Biol 2: 463-465
    • (2000) Nat Cell Biol , vol.2 , pp. 463-465
    • Zhang, Z.1    Nadeau, P.2    Song, W.3
  • 18
    • 0033535504 scopus 로고    scopus 로고
    • A presenilin-1-dependent gammasecretase-like protease mediates release of Notch intracellular domain
    • De Strooper B, Annaert W, Cupers P et al (1999) A presenilin-1-dependent gammasecretase-like protease mediates release of Notch intracellular domain. Nature 398:518-522
    • (1999) Nature , vol.398 , pp. 518-522
    • De Strooper, B.1    Annaert, W.2    Cupers, P.3
  • 19
    • 0036266624 scopus 로고    scopus 로고
    • The search for gamma-secretase and development of inhibitors
    • Tsai JY, Wolfe MS, Xia W (2002) The search for gamma-secretase and development of inhibitors. Curr Med Chem 9:1087-1106
    • (2002) Curr Med Chem , vol.9 , pp. 1087-1106
    • Tsai, J.Y.1    Wolfe, M.S.2    Xia, W.3
  • 20
    • 76849086405 scopus 로고    scopus 로고
    • The secretases: Enzymes with therapeutic potential in Alzheimer disease
    • De Strooper B, Vassar R, Golde T (2010) The secretases: enzymes with therapeutic potential in Alzheimer disease. Nat Rev Neurol 6: 99-107
    • (2010) Nat Rev Neurol , vol.6 , pp. 99-107
    • De Strooper, B.1    Vassar, R.2    Golde, T.3
  • 21
    • 0035912829 scopus 로고    scopus 로고
    • Gamma-secretase inhibitors repress thymocyte development
    • Hadland BK, Manley NR, Su D et al (2001) Gamma-secretase inhibitors repress thymocyte development. Proc Natl Acad Sci USA 98:7487-7491
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7487-7491
    • Hadland, B.K.1    Manley, N.R.2    Su, D.3
  • 22
    • 0036023971 scopus 로고    scopus 로고
    • A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafi sh
    • Geling A, Steiner H, Willem M et al (2002) A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafi sh. EMBO Rep 3: 688-694
    • (2002) EMBO Rep , vol.3 , pp. 688-694
    • Geling, A.1    Steiner, H.2    Willem, M.3
  • 23
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: Unfolding the activation mechanism
    • Kopan R, Ilagan MX (2009) The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137:216-233
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 24
    • 55449135598 scopus 로고    scopus 로고
    • The molecular logic of Notch signaling-A structural and biochemical perspective
    • Gordon WR, Arnett KL, Blacklow SC (2008) The molecular logic of Notch signaling-a structural and biochemical perspective. J Cell Sci 121:3109-3119
    • (2008) J Cell Sci , vol.121 , pp. 3109-3119
    • Gordon, W.R.1    Arnett, K.L.2    Blacklow, S.C.3
  • 25
    • 5044225888 scopus 로고    scopus 로고
    • Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
    • Weng AP, Ferrando AA, Lee W et al (2004) Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306:269-271
    • (2004) Science , vol.306 , pp. 269-271
    • Weng, A.P.1    Ferrando, A.A.2    Lee, W.3
  • 26
    • 78649991073 scopus 로고    scopus 로고
    • Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies
    • Aster JC, Blacklow SC, Pear WS (2011) Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies. J Pathol 223:262-273
    • (2011) J Pathol , vol.223 , pp. 262-273
    • Aster, J.C.1    Blacklow, S.C.2    Pear, W.S.3
  • 27
    • 33746546368 scopus 로고    scopus 로고
    • C-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
    • Weng AP, Millholland JM, Yashiro-Ohtani Y et al (2006) c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev 20:2096-2109
    • (2006) Genes Dev , vol.20 , pp. 2096-2109
    • Weng, A.P.1    Millholland, J.M.2    Yashiro-Ohtani, Y.3
  • 28
    • 0029942842 scopus 로고    scopus 로고
    • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    • Pear WS, Aster JC, Scott ML et al (1996) Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med 183: 2283-2291
    • (1996) J Exp Med , vol.183 , pp. 2283-2291
    • Pear, W.S.1    Aster, J.C.2    Scott, M.L.3
  • 29
    • 84880729295 scopus 로고    scopus 로고
    • Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals
    • Bailis W, Yashiro-Ohtani Y, Fang TC et al (2013) Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. Immunity 39: 148-159
    • (2013) Immunity , vol.39 , pp. 148-159
    • Bailis, W.1    Yashiro-Ohtani, Y.2    Fang, T.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.