Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos

Mechanisms of Development

Volumn 98, Issue 1-2, 2000, Pages 175-178

  Leimeister, Cornelia ^a   Schumacher, Nina ^a   Steidl, Christian ^a   Gessler, Manfred ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Arteries; Basic helix loop helix; CADASIL; Cranial ganglia; Delta; Hairy; Hey; Mouse; Notch; Presomititic mesoderm; Smooth muscles; Somites; Somitogenesis; Spinal ganglia; Thymus; Vasculature

Indexed keywords

HELIX LOOP HELIX PROTEIN; PROTEIN NOTCH;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; MISSENSE MUTATION; MOUSE; MUTANT; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOMITE; SPINAL GANGLION; VASCULAR SMOOTH MUSCLE;

ANIMAL; EMBRYO AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HELIX-LOOP-HELIX MOTIFS; HUMAN; IN SITU HYBRIDIZATION; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MUTATION; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION FACTORS;

EID: 0034333446     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(00)00459-7     Document Type: Article

References (19)

1. Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse
2. Notch1 is required for the coordinate segmentation of somites
3. Maintenance of somite borders in mice requires the Delta homologue DII1
4. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
5. The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
6. Notch signaling is essential for vascular morphogenesis in mice
7. Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family
8. Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis
9. Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers
10. Comparative analysis of the human and mouse Hey1 promoter: Hey genes represent a novel family of Notch target genes
11. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
12. Myogenic lineages within the developing somite
13. Deficient T cell fate specification in mice with an induced inactivation of Notch1
14. Expression analysis of a Notch homologue in the mouse embryo
15. Dll4, a novel Notch ligand expressed in arterial endothelium
16. Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family
17. Notch1 is essential for postimplantation development in mice
18. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
19. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1