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Volumn 12, Issue 4, 2015, Pages 653-667

Elastin-like polypeptide for improved drug delivery for anticancer therapy: Preclinical studies and future applications

Author keywords

Anticancer therapy; Drug delivery; Lastin like polypeptide; Thermally targeting

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PENETRATING PEPTIDE; DOXORUBICIN; DRUG CARRIER; ELASTIN; ELASTIN LIKE POLYPEPTIDE; MYC PROTEIN; PACLITAXEL; UNCLASSIFIED DRUG; PEPTIDE;

EID: 84925281070     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.974546     Document Type: Review
Times cited : (28)

References (94)
  • 2
    • 0035134688 scopus 로고    scopus 로고
    • Interferon in oncological practice: Review of interferon biology, clinical applications, and toxicities
    • Jonasch E, Haluska FG. Interferon in oncological practice: review of interferon biology, clinical applications, and toxicities. Oncologist 2001;6(1):34-55
    • (2001) Oncologist , vol.6 , Issue.1 , pp. 34-55
    • Jonasch, E.1    Haluska, F.G.2
  • 3
    • 84860188105 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines: Current status and moving forward
    • Schlom J. Therapeutic cancer vaccines: current status and moving forward. J Natl Cancer Inst 2012;104(8):599-613
    • (2012) J Natl Cancer Inst , vol.104 , Issue.8 , pp. 599-613
    • Schlom, J.1
  • 4
    • 84883821225 scopus 로고    scopus 로고
    • Antibody therapeutics in cancer
    • Sliwkowski MX, Mellman I. Antibody therapeutics in cancer. Science 2013;341(6151):1192-8
    • (2013) Science , vol.341 , Issue.6151 , pp. 1192-1198
    • Sliwkowski, M.X.1    Mellman, I.2
  • 5
    • 0034951384 scopus 로고    scopus 로고
    • STI571: Targeting BCR-ABL as therapy for CML
    • Mauro MJ, Druker BJ. STI571: targeting BCR-ABL as therapy for CML. Oncologist 2001;6(3):233-8
    • (2001) Oncologist , vol.6 , Issue.3 , pp. 233-238
    • Mauro, M.J.1    Druker, B.J.2
  • 6
    • 0034880214 scopus 로고    scopus 로고
    • Cremophor EL: The drawbacks and advantages of vehicle selection for drug formulation
    • Gelderblom H, Verweij J, Nooter K, Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer 2001;37(13):1590-8
    • (2001) Eur J Cancer , vol.37 , Issue.13 , pp. 1590-1598
    • Gelderblom, H.1    Verweij, J.2    Nooter, K.3    Sparreboom, A.4
  • 7
    • 3442891161 scopus 로고    scopus 로고
    • Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR) combining anti-EGFR antibody with tyrosine kinase inhibitor
    • Huang S, Armstrong EA, Benavente S, et al. Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR) combining anti-EGFR antibody with tyrosine kinase inhibitor. Cancer Res 2004;64(15):5355-62
    • (2004) Cancer Res , vol.64 , Issue.15 , pp. 5355-5362
    • Huang, S.1    Armstrong, E.A.2    Benavente, S.3
  • 8
    • 0028833556 scopus 로고
    • Macromolecular drug carrier systems in cancer chemotherapy: Macromolecular prodrugs
    • Takakura Y, Hashida M. Macromolecular drug carrier systems in cancer chemotherapy: macromolecular prodrugs. Crit Rev Oncol Hematol 1995;18(3):207-31
    • (1995) Crit Rev Oncol Hematol , vol.18 , Issue.3 , pp. 207-231
    • Takakura, Y.1    Hashida, M.2
  • 9
    • 57249084773 scopus 로고    scopus 로고
    • Polymeric micellar delivery systems in oncology
    • Matsumura Y. Polymeric micellar delivery systems in oncology. Jpn J Clin Oncol 2008;38(12):793-802
    • (2008) Jpn J Clin Oncol , vol.38 , Issue.12 , pp. 793-802
    • Matsumura, Y.1
  • 10
    • 84873252557 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: From concept to clinical applications
    • Allen TM, Cullis PR. Liposomal drug delivery systems: from concept to clinical applications. Adv Drug Deliv Rev 2013;65(1):36-48
    • (2013) Adv Drug Deliv Rev , vol.65 , Issue.1 , pp. 36-48
    • Allen, T.M.1    Cullis, P.R.2
  • 11
    • 84893480440 scopus 로고    scopus 로고
    • Facts, fallacies and future of dissolution testing of polysaccharide based colon specific drug delivery
    • Kotla NG, Gulati M, Singh SK, Shivapooja A. Facts, fallacies and future of dissolution testing of polysaccharide based colon specific drug delivery. J Control Release 2014;178:55-62
    • (2014) J Control Release , vol.178 , pp. 55-62
    • Kotla, N.G.1    Gulati, M.2    Singh, S.K.3    Shivapooja, A.4
  • 12
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res1986;46(12 Part 1):6387-92
    • (1986) Cancer Res , vol.46 , Issue.12 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 13
    • 84896699451 scopus 로고    scopus 로고
    • Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
    • Bertrand N, Wu J, Xu X, et al. Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv Drug Deliv Rev 2014;66:2-25
    • (2014) Adv Drug Deliv Rev , vol.66 , pp. 2-25
    • Bertrand, N.1    Wu, J.2    Xu, X.3
  • 14
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumorselective macromolecular drug targeting
    • Maeda H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumorselective macromolecular drug targeting. Adv Enzyme Regul 2001;41(1):189-207
    • (2001) Adv Enzyme Regul , vol.41 , Issue.1 , pp. 189-207
    • Maeda, H.1
  • 15
    • 34547653668 scopus 로고    scopus 로고
    • Enhanced permeability and retention of macromolecular drugs in solid tumors: A royal gate for targeted anticancer nanomedicines
    • Greish K. Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J Drug Target 2007;15(7-8):457-64
    • (2007) J Drug Target , vol.15 , Issue.7-8 , pp. 457-464
    • Greish, K.1
  • 16
    • 75749134040 scopus 로고    scopus 로고
    • Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations
    • Lammers T. Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations. Adv Drug Deliv Rev 2010;62(2):203-30
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.2 , pp. 203-230
    • Lammers, T.1
  • 17
    • 79953053224 scopus 로고    scopus 로고
    • Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects
    • Maruyama K. Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects. Adv Drug Deliv Rev 2011;63(3):161-9
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.3 , pp. 161-169
    • Maruyama, K.1
  • 18
    • 84862698355 scopus 로고    scopus 로고
    • Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
    • Lammers T, Kiessling F, Hennink WE, Storm G. Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress. J Control Release 2012;161(2):175-87
    • (2012) J Control Release , vol.161 , Issue.2 , pp. 175-187
    • Lammers, T.1    Kiessling, F.2    Hennink, W.E.3    Storm, G.4
  • 19
    • 2142714017 scopus 로고    scopus 로고
    • Monoclonal antibodies as therapeutic agents for cancer
    • Harris M. Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol 2004;5(5):292-302
    • (2004) Lancet Oncol , vol.5 , Issue.5 , pp. 292-302
    • Harris, M.1
  • 20
    • 0036781811 scopus 로고    scopus 로고
    • Ligand-targeted therapeutics in anticancer therapy
    • Allen TM. Ligand-targeted therapeutics in anticancer therapy. Nat Rev Cancer 2002;2(10):750-63
    • (2002) Nat Rev Cancer , vol.2 , Issue.10 , pp. 750-763
    • Allen, T.M.1
  • 21
    • 84896489902 scopus 로고    scopus 로고
    • Targeted and ultrasoundtriggered drug delivery using liposomes co-modified with cancer cell-targeting aptamers and a thermosensitive polymer
    • Ninomiya K, Yamashita T, Kawabata S, Shimizu N. Targeted and ultrasoundtriggered drug delivery using liposomes co-modified with cancer cell-targeting aptamers and a thermosensitive polymer. Ultrason Sonochem 2014;21(4):1482-8
    • (2014) Ultrason Sonochem , vol.21 , Issue.4 , pp. 1482-1488
    • Ninomiya, K.1    Yamashita, T.2    Kawabata, S.3    Shimizu, N.4
  • 22
    • 71849085389 scopus 로고    scopus 로고
    • Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application
    • Floss DM, Schallau K, Rose-John S, et al. Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application. Trends Biotechnol 2010;28(1):37-45
    • (2010) Trends Biotechnol , vol.28 , Issue.1 , pp. 37-45
    • Floss, D.M.1    Schallau, K.2    Rose-John, S.3
  • 23
    • 78649887035 scopus 로고    scopus 로고
    • Drug delivery to solid tumors by elastinlike polypeptides
    • McDaniel JR, Callahan DJ, Chilkoti A. Drug delivery to solid tumors by elastinlike polypeptides. Adv Drug Deliv Rev 2010;62(15):1456-67
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.15 , pp. 1456-1467
    • McDaniel, J.R.1    Callahan, D.J.2    Chilkoti, A.3
  • 24
    • 84901339386 scopus 로고    scopus 로고
    • Penetrating the cell membrane, thermal targeting and novel anticancer drugs: The development of thermally targeted, elastin-like polypeptide cancer therapeutics
    • Ryu JS, Kuna M, Raucher D. Penetrating the cell membrane, thermal targeting and novel anticancer drugs: the development of thermally targeted, elastin-like polypeptide cancer therapeutics. Ther deliv 2014;5(4):429-45
    • (2014) Ther Deliv , vol.5 , Issue.4 , pp. 429-445
    • Ryu, J.S.1    Kuna, M.2    Raucher, D.3
  • 25
    • 33745940910 scopus 로고    scopus 로고
    • Biocompatibility of elastin-like polymer poly (VPAVG) microparticles: In vitro and in vivo studies
    • Rincon A, Molina-Martinez I, de Las Heras B, et al. Biocompatibility of elastin-like polymer poly (VPAVG) microparticles: in vitro and in vivo studies. Journal of Biomedical Materials Research Part A 2006;78(2):343-51
    • (2006) Journal of Biomedical Materials Research Part a , vol.78 , Issue.2 , pp. 343-351
    • Rincon, A.1    Molina-Martinez, I.2    De Las Heras, B.3
  • 27
    • 33847253510 scopus 로고    scopus 로고
    • Effect of NaCl on the exothermic and endothermic components of the inverse temperature transition of a model elastinlike polymer
    • Reguera J, Urry DW, Parker TM, et al. Effect of NaCl on the exothermic and endothermic components of the inverse temperature transition of a model elastinlike polymer. Biomacromolecules 2007;8(2):354-8
    • (2007) Biomacromolecules , vol.8 , Issue.2 , pp. 354-358
    • Reguera, J.1    Urry, D.W.2    Parker, T.M.3
  • 28
    • 0026926763 scopus 로고
    • Hydrophobicity scale for proteins based on inverse temperature transitions
    • Urry DW, Gowda DC, Parker TM, et al. Hydrophobicity scale for proteins based on inverse temperature transitions. Biopolymers 1992;32(9):1243-50
    • (1992) Biopolymers , vol.32 , Issue.9 , pp. 1243-1250
    • Urry, D.W.1    Gowda, D.C.2    Parker, T.M.3
  • 29
    • 0032538330 scopus 로고    scopus 로고
    • Short elastin-like peptides exhibit the same temperature-induced structural transitions as elastin polymers: Implications for protein engineering
    • Reiersen H, Clarke AR, Rees AR. Short elastin-like peptides exhibit the same temperature-induced structural transitions as elastin polymers: implications for protein engineering. J Mol Biol 1998;283(1):255-64
    • (1998) J Mol Biol , vol.283 , Issue.1 , pp. 255-264
    • Reiersen, H.1    Clarke, A.R.2    Rees, A.R.3
  • 30
    • 84856587254 scopus 로고    scopus 로고
    • Secretion of elastin-like polypeptides with different transition temperatures by Pichia pastoris
    • Schipperus R, Eggink G, de Wolf FA. Secretion of elastin-like polypeptides with different transition temperatures by Pichia pastoris. Biotechnol Prog 2011;28(1):242-7
    • (2011) Biotechnol Prog , vol.28 , Issue.1 , pp. 242-247
    • Schipperus, R.1    Eggink, G.2    De Wolf, F.A.3
  • 31
    • 84984621304 scopus 로고
    • Temperature of polypeptide inverse temperature transition dependes on mean residue hydrophobidity
    • Urry DW, Luan C-H, Parker TM, et al. Temperature of polypeptide inverse temperature transition dependes on mean residue hydrophobidity. J Am Chem Soc 1991;113(11):4346-38
    • (1991) J am Chem Soc , vol.113 , Issue.11 , pp. 4346-4438
    • Urry, D.W.1    Luan, C.-H.2    Parker, T.M.3
  • 32
    • 84907217006 scopus 로고    scopus 로고
    • The potential of recombinant human elastin-like polypeptides for drug delivery
    • Ciofani G, Genchi GG, Mattoli V, et al. The potential of recombinant human elastin-like polypeptides for drug delivery. Expert Opin Drug Deliv 2014(0):1-6
    • (2014) Expert Opin Drug Deliv , Issue.0 , pp. 1-6
    • Ciofani, G.1    Genchi, G.G.2    Mattoli, V.3
  • 33
    • 28844455732 scopus 로고    scopus 로고
    • Expression and characterization of human-elastin-repeat-based temperatureresponsive protein polymers for biotechnological purposes
    • Bandiera A, Taglienti A, Micali F, et al. Expression and characterization of human-elastin-repeat-based temperatureresponsive protein polymers for biotechnological purposes. Biotechnol Appl Biochem 2005;42(3):247-56
    • (2005) Biotechnol Appl Biochem , vol.42 , Issue.3 , pp. 247-256
    • Bandiera, A.1    Taglienti, A.2    Micali, F.3
  • 34
    • 0032739304 scopus 로고    scopus 로고
    • Purification of recombinant proteins by fusion with thermally-responsive polypeptides
    • Meyer DE, Chilkoti A. Purification of recombinant proteins by fusion with thermally-responsive polypeptides. Nat Biotechnol 1999;17(11):1112-15
    • (1999) Nat Biotechnol , vol.17 , Issue.11 , pp. 1112-1115
    • Meyer, D.E.1    Chilkoti, A.2
  • 35
    • 59449097473 scopus 로고    scopus 로고
    • Genetically engineered elastin-like polymer as a substratum to culture cells from the ocular surface
    • Martinez-Osorio H, Juarez-Campo M, Diebold Y, et al. Genetically engineered elastin-like polymer as a substratum to culture cells from the ocular surface. Curr Eye Res 2009;34(1):48-56
    • (2009) Curr Eye Res , vol.34 , Issue.1 , pp. 48-56
    • Martinez-Osorio, H.1    Juarez-Campo, M.2    Diebold, Y.3
  • 36
    • 24044513316 scopus 로고    scopus 로고
    • Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide
    • Betre H, Ong SR, Guilak F, et al. Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. Biomaterials 2006;27(1):91-9
    • (2006) Biomaterials , vol.27 , Issue.1 , pp. 91-99
    • Betre, H.1    Ong, S.R.2    Guilak, F.3
  • 37
    • 33947315594 scopus 로고    scopus 로고
    • Elastin-like polypeptide fusions enhance the accumulation of recombinant proteins in tobacco leaves
    • Patel J, Zhu H, Menassa R, et al. Elastin-like polypeptide fusions enhance the accumulation of recombinant proteins in tobacco leaves. Transgenic Res 2007;16(2):239-49
    • (2007) Transgenic Res , vol.16 , Issue.2 , pp. 239-249
    • Patel, J.1    Zhu, H.2    Menassa, R.3
  • 38
    • 33749342367 scopus 로고    scopus 로고
    • Purification of an elastin-like fusion protein by microfiltration
    • Ge X, Trabbic-Carlson K, Chilkoti A, Filipe CD. Purification of an elastin-like fusion protein by microfiltration. Biotechnol Bioeng 2006;95(3):424-32
    • (2006) Biotechnol Bioeng , vol.95 , Issue.3 , pp. 424-432
    • Ge, X.1    Trabbic-Carlson, K.2    Chilkoti, A.3    Filipe, C.D.4
  • 39
    • 77956493179 scopus 로고    scopus 로고
    • Elastin-like polypeptides as a purification tag for recombinant proteins
    • Hassouneh W, Christensen T, Chilkoti A. Elastin-like polypeptides as a purification tag for recombinant proteins. Curr Protoc Protein Sci 2010;doi: 10.1002/0471140864. ps0611s61
    • (2010) Curr Protoc Protein Sci
    • Hassouneh, W.1    Christensen, T.2    Chilkoti, A.3
  • 40
    • 80052281119 scopus 로고    scopus 로고
    • A cost-effective ELPintein coupling system for recombinant protein purification from plant production platform
    • Tian L, Sun SS. A cost-effective ELPintein coupling system for recombinant protein purification from plant production platform. PLoS One 2011;6(8):e24183
    • (2011) PLoS One , vol.6 , Issue.8 , pp. e24183
    • Tian, L.1    Sun, S.S.2
  • 41
    • 0036739152 scopus 로고    scopus 로고
    • Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair
    • Betre H, Setton LA, Meyer DE, Chilkoti A. Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair. Biomacromolecules 2002;3(5):910-16
    • (2002) Biomacromolecules , vol.3 , Issue.5 , pp. 910-916
    • Betre, H.1    Setton, L.A.2    Meyer, D.E.3    Chilkoti, A.4
  • 42
    • 84872760337 scopus 로고    scopus 로고
    • In vitro evaluation of elastin-like polypeptide - Collagen composite scaffold for bone tissue engineering
    • Amruthwar SS, Janorkar AV. In vitro evaluation of elastin-like polypeptide - collagen composite scaffold for bone tissue engineering. Dent Mater 2013;29(2):211-20
    • (2013) Dent Mater , vol.29 , Issue.2 , pp. 211-220
    • Amruthwar, S.S.1    Janorkar, A.V.2
  • 43
    • 84892617027 scopus 로고    scopus 로고
    • Stimuli-induced release of compounds from elastin biomimetic matrix
    • Bandiera A, Markulin A, Corich L, et al. Stimuli-induced release of compounds from elastin biomimetic matrix. Biomacromolecules 2013;15(1):416-22
    • (2013) Biomacromolecules , vol.15 , Issue.1 , pp. 416-422
    • Bandiera, A.1    Markulin, A.2    Corich, L.3
  • 44
    • 84886589420 scopus 로고    scopus 로고
    • Improved neural progenitor cell proliferation and differentiation on poly (lactide-co-glycolide) scaffolds coated with elastin-like polypeptide
    • Choi SK, Park JK, Lee KM, et al. Improved neural progenitor cell proliferation and differentiation on poly (lactide-co-glycolide) scaffolds coated with elastin-like polypeptide. J Biomed Mater Res B Appl Biomater 2013;101(8):1329-39
    • (2013) J Biomed Mater Res B Appl Biomater , vol.101 , Issue.8 , pp. 1329-1339
    • Choi, S.K.1    Park, J.K.2    Lee, K.M.3
  • 45
    • 84901070463 scopus 로고    scopus 로고
    • Recombinant human elastin-like magnetic microparticles for drug delivery and targeting
    • Ciofani G, Genchi GG, Guardia P, et al. Recombinant human elastin-like magnetic microparticles for drug delivery and targeting. Macromol Biosci 2014;14(5):632-42
    • (2014) Macromol Biosci , vol.14 , Issue.5 , pp. 632-642
    • Ciofani, G.1    Genchi, G.G.2    Guardia, P.3
  • 46
    • 0035476258 scopus 로고    scopus 로고
    • Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition
    • Raucher D, Chilkoti A. Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition. Cancer Res 2001;61(19):7163-70
    • (2001) Cancer Res , vol.61 , Issue.19 , pp. 7163-7170
    • Raucher, D.1    Chilkoti, A.2
  • 47
    • 0035866357 scopus 로고    scopus 로고
    • Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia
    • Meyer DE, Kong GA, Dewhirst MW, et al. Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia. Cancer Res 2001;61(4):1548-54
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1548-1554
    • Meyer, D.E.1    Kong, G.A.2    Dewhirst, M.W.3
  • 48
    • 70549101139 scopus 로고    scopus 로고
    • Self-assembling chimeric polypeptide - Conjugate nanoparticles that abolish tumours after a single injection
    • MacKay JA, Chen M, McDaniel JR, et al. Self-assembling chimeric polypeptide - conjugate nanoparticles that abolish tumours after a single injection. Nat Mater 2009;8(12):993-9
    • (2009) Nat Mater , vol.8 , Issue.12 , pp. 993-999
    • MacKay, J.A.1    Chen, M.2    McDaniel, J.R.3
  • 49
    • 0035816166 scopus 로고    scopus 로고
    • Drug targeting using thermally responsive polymers and local hyperthermia
    • Meyer DE, Shin BC, Kong GA, et al. Drug targeting using thermally responsive polymers and local hyperthermia. J Control Release 2001;74(1-3):213-24
    • (2001) J Control Release , vol.74 , Issue.1-3 , pp. 213-224
    • Meyer, D.E.1    Shin, B.C.2    Kong, G.A.3
  • 51
    • 34249316870 scopus 로고    scopus 로고
    • Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors
    • Dreher MR, Liu W, Michelich CR, et al. Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors. Cancer Res 2007;67(9):4418-24
    • (2007) Cancer Res , vol.67 , Issue.9 , pp. 4418-4424
    • Dreher, M.R.1    Liu, W.2    Michelich, C.R.3
  • 52
    • 84908370947 scopus 로고    scopus 로고
    • Elastin-like polypeptides: The influence of its molecular weight on local hyperthermiainduced tumor accumulation
    • Ryu JS, Raucher D. Elastin-like polypeptides: the influence of its molecular weight on local hyperthermiainduced tumor accumulation. Eur J Pharm Biopharm 2014
    • (2014) Eur J Pharm Biopharm
    • Ryu, J.S.1    Raucher, D.2
  • 53
    • 84859505371 scopus 로고    scopus 로고
    • A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth
    • Bidwell GL III, Perkins E, Raucher D. A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth. Cancer Lett 2012;319(2):136-43
    • (2012) Cancer Lett , vol.319 , Issue.2 , pp. 136-143
    • Bidwell, G.L.1    Perkins, E.2    Raucher, D.3
  • 54
    • 34547585979 scopus 로고    scopus 로고
    • Biodegradable polymers as biomaterials
    • Nair LS, Laurencin CT. Biodegradable polymers as biomaterials. Prog Polym Sci 2007;32(8):762-98
    • (2007) Prog Polym Sci , vol.32 , Issue.8 , pp. 762-798
    • Nair, L.S.1    Laurencin, C.T.2
  • 55
    • 0141955920 scopus 로고    scopus 로고
    • Evaluation of an elastin-like polypeptide - Doxorubicin conjugate for cancer therapy
    • Dreher MR, Raucher D, Balu N, et al. Evaluation of an elastin-like polypeptide - doxorubicin conjugate for cancer therapy. J Control Release 2003;91(1):31-43
    • (2003) J Control Release , vol.91 , Issue.1 , pp. 31-43
    • Dreher, M.R.1    Raucher, D.2    Balu, N.3
  • 56
    • 84856544910 scopus 로고    scopus 로고
    • A thermally responsive biopolymer conjugated to an acidsensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis
    • Moktan S, Ryppa C, Kratz F, Raucher D. A thermally responsive biopolymer conjugated to an acidsensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis. Invest New Drugs 2012;30(1):236-48
    • (2012) Invest New Drugs , vol.30 , Issue.1 , pp. 236-248
    • Moktan, S.1    Ryppa, C.2    Kratz, F.3    Raucher, D.4
  • 57
    • 0037325515 scopus 로고    scopus 로고
    • Synthesis and in vitro efficacy of acid-sensitive poly (ethylene glycol) paclitaxel conjugates
    • Rodrigues PC, Scheuermann K, Stockmar C, et al. Synthesis and in vitro efficacy of acid-sensitive poly (ethylene glycol) paclitaxel conjugates. Bioorg Med Chem Lett 2003;13(3):355-60
    • (2003) Bioorg Med Chem Lett , vol.13 , Issue.3 , pp. 355-360
    • Rodrigues, P.C.1    Scheuermann, K.2    Stockmar, C.3
  • 58
    • 84867334463 scopus 로고    scopus 로고
    • Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides
    • Moktan S, Raucher D. Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides. Int J Pept Res Ther 2012;18(3):227-37
    • (2012) Int J Pept Res Ther , vol.18 , Issue.3 , pp. 227-237
    • Moktan, S.1    Raucher, D.2
  • 59
    • 23144442466 scopus 로고    scopus 로고
    • Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy
    • Bidwell GL, Raucher D. Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy. Mol Cancer Ther 2005;4(7):1076-85
    • (2005) Mol Cancer Ther , vol.4 , Issue.7 , pp. 1076-1085
    • Bidwell, G.L.1    Raucher, D.2
  • 60
    • 84890809023 scopus 로고    scopus 로고
    • A novel two-step mild hyperthermia for advanced liposomal chemotherapy
    • Li Lten Hagen TL, Haeri A, et al. A novel two-step mild hyperthermia for advanced liposomal chemotherapy. J Control Release 2014;174:202-8
    • (2014) J Control Release , vol.174 , pp. 202-208
    • Li Lten Hagen, T.L.1    Haeri, A.2
  • 61
    • 84894656925 scopus 로고    scopus 로고
    • Gemcitabine treatment of rat soft tissue sarcoma with phosphatidyldiglycerolbased thermosensitive liposomes
    • Limmer S, Hahn J, Schmidt R, et al. Gemcitabine treatment of rat soft tissue sarcoma with phosphatidyldiglycerolbased thermosensitive liposomes. Pharm Res 2014;1-11
    • (2014) Pharm Res , pp. 1-11
    • Limmer, S.1    Hahn, J.2    Schmidt, R.3
  • 62
    • 77955470886 scopus 로고    scopus 로고
    • Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors
    • Koning GA, Eggermont AM, Lindner LH, ten Hagen TL. Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors. Pharm Res 2010;27(8):1750-4
    • (2010) Pharm Res , vol.27 , Issue.8 , pp. 1750-1754
    • Koning, G.A.1    Eggermont, A.M.2    Lindner, L.H.3    Ten Hagen, T.L.4
  • 63
    • 0036339812 scopus 로고    scopus 로고
    • Hyperthermia in combined treatment of cancer
    • Wust P, Hildebrandt B, Sreenivasa G, et al. Hyperthermia in combined treatment of cancer. Lancet Oncol 2002;3(8):487-97
    • (2002) Lancet Oncol , vol.3 , Issue.8 , pp. 487-497
    • Wust, P.1    Hildebrandt, B.2    Sreenivasa, G.3
  • 64
    • 80051916578 scopus 로고    scopus 로고
    • Nanoscale drug delivery and hyperthermia: the materials design and preclinical and clinical testing of low temperature-sensitive liposomes used in combination with mild hyperthermia in the treatment of local cancer
    • Landon CD, Park JY, Needham D, Dewhirst MW. Nanoscale drug delivery and hyperthermia: the materials design and preclinical and clinical testing of low temperature-sensitive liposomes used in combination with mild hyperthermia in the treatment of local cancer. Open Nanomed J 2011;3:38-64
    • (2011) Open Nanomed J , vol.3 , pp. 38-64
    • Landon, C.D.1    Park, J.Y.2    Needham, D.3    Dewhirst, M.W.4
  • 65
    • 84877798656 scopus 로고    scopus 로고
    • Thermosensitive liposomes for localized delivery and triggered release of chemotherapy
    • Ta T, Porter TM. Thermosensitive liposomes for localized delivery and triggered release of chemotherapy. J Control Release 2013;169(1-2):112-25
    • (2013) J Control Release , vol.169 , Issue.1-2 , pp. 112-125
    • Ta, T.1    Porter, T.M.2
  • 66
    • 77952231544 scopus 로고    scopus 로고
    • Cell-penetrating peptides and their therapeutic applications
    • Sebbage V. Cell-penetrating peptides and their therapeutic applications. Biosciencehorizons 2009;2:64-72
    • (2009) Biosciencehorizons , vol.2 , pp. 64-72
    • Sebbage, V.1
  • 67
    • 27744525788 scopus 로고    scopus 로고
    • Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery
    • Massodi I, Bidwell GL III, Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery. J Control Release 2005;108(2):396-408
    • (2005) J Control Release , vol.108 , Issue.2 , pp. 396-408
    • Massodi, I.1    Bidwell, G.L.2    Raucher, D.3
  • 68
    • 61649103094 scopus 로고    scopus 로고
    • Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides
    • Bidwell GL III, Davis AN, Raucher D. Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides. J Control Release 2009;135(1):2-10
    • (2009) J Control Release , vol.135 , Issue.1 , pp. 2-10
    • Bidwell, G.L.1    Davis, A.N.2    Raucher, D.3
  • 69
    • 77951254936 scopus 로고    scopus 로고
    • A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation
    • Bidwell GL III, Whittom AA, Thomas E, et al. A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation. Peptides 2010;31(5):834-41
    • (2010) Peptides , vol.31 , Issue.5 , pp. 834-841
    • Bidwell, G.L.1    Whittom, A.A.2    Thomas, E.3
  • 70
    • 73549108720 scopus 로고    scopus 로고
    • Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier
    • Massodi I, Moktan S, Rawat A, et al. Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. Int J Cancer 2010;126(2):533-44
    • (2010) Int J Cancer , vol.126 , Issue.2 , pp. 533-544
    • Massodi, I.1    Moktan, S.2    Rawat, A.3
  • 71
    • 84872872856 scopus 로고    scopus 로고
    • Thermally targeted delivery of a c-Myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma model
    • Bidwell GL III, Perkins E, Hughes J, et al. Thermally targeted delivery of a c-Myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma model. PLoS One 2013;8(1):e55104
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e55104
    • Bidwell, G.L.1    Perkins, E.2    Hughes, J.3
  • 72
    • 84900508774 scopus 로고    scopus 로고
    • Anti-tumor efficacy of a therapeutic peptide based on thermo-responsive elastin-like polypeptide in combination with gemcitabine
    • Ryu JS, Raucher D. Anti-tumor efficacy of a therapeutic peptide based on thermo-responsive elastin-like polypeptide in combination with gemcitabine. Cancer Lett 2014;348(1-2):177-84
    • (2014) Cancer Lett , vol.348 , Issue.1-2 , pp. 177-184
    • Ryu, J.S.1    Raucher, D.2
  • 73
    • 67649834226 scopus 로고    scopus 로고
    • Application of thermally responsive elastin-like polypeptide fused to a lactoferrin-derived peptide for treatment of pancreatic cancer
    • Massodi I, Thomas E, Raucher D. Application of thermally responsive elastin-like polypeptide fused to a lactoferrin-derived peptide for treatment of pancreatic cancer. Molecules 2009;14(6):1999-2015
    • (2009) Molecules , vol.14 , Issue.6 , pp. 1999-2015
    • Massodi, I.1    Thomas, E.2    Raucher, D.3
  • 74
    • 1842790378 scopus 로고    scopus 로고
    • c-Myc as a therapeutic target in cancer
    • Prochownik EV. c-Myc as a therapeutic target in cancer. Expert Rev Anticancer Ther 2004;4(2):289-302
    • (2004) Expert Rev Anticancer Ther , vol.4 , Issue.2 , pp. 289-302
    • Prochownik, E.V.1
  • 75
    • 17944392627 scopus 로고    scopus 로고
    • Inhibition of cancer cell growth and c-Myc transcriptional activity by a c-Myc helix 1-type peptide fused to an internalization sequence
    • Giorello L, Clerico L, Pescarolo MP, et al. Inhibition of cancer cell growth and c-Myc transcriptional activity by a c-Myc helix 1-type peptide fused to an internalization sequence. Cancer Res 1998;58(16):3654-9
    • (1998) Cancer Res , vol.58 , Issue.16 , pp. 3654-3659
    • Giorello, L.1    Clerico, L.2    Pescarolo, M.P.3
  • 76
    • 84876728629 scopus 로고    scopus 로고
    • Cell-Penetrating Peptide-Mediated Therapeutic Molecule Delivery into the Central Nervous System
    • Zou LL, Ma JL, Wang T, et al. Cell-Penetrating Peptide-Mediated Therapeutic Molecule Delivery into the Central Nervous System. Curr Neuropharmacol 2013;11(2):197-208
    • (2013) Curr Neuropharmacol , vol.11 , Issue.2 , pp. 197-208
    • Zou, L.L.1    Ma, J.L.2    Wang, T.3
  • 77
    • 82855172080 scopus 로고    scopus 로고
    • The design and delivery of a thermally responsive peptide to inhibit S100Bmediated neurodegeneration
    • Hearst SM, Walker LR, Shao Q, et al. The design and delivery of a thermally responsive peptide to inhibit S100Bmediated neurodegeneration. Neuroscience 2011;197:369-80
    • (2011) Neuroscience , vol.197 , pp. 369-380
    • Hearst, S.M.1    Walker, L.R.2    Shao, Q.3
  • 78
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 2002;1(8):639-49
    • (2002) Mol Cancer Ther , vol.1 , Issue.8 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 79
    • 0035325262 scopus 로고    scopus 로고
    • Inhibition of cell proliferation by the PCNA-binding region of p21 expressed as a GFP miniprotein
    • Mattock H, Lane DP, Warbrick E. Inhibition of cell proliferation by the PCNA-binding region of p21 expressed as a GFP miniprotein. Exp Cell Res 2001;265(2):234-41
    • (2001) Exp Cell Res , vol.265 , Issue.2 , pp. 234-241
    • Mattock, H.1    Lane, D.P.2    Warbrick, E.3
  • 80
    • 84891840030 scopus 로고    scopus 로고
    • Kuna MRaucher D. Thermally targeted p21 peptide enhances bortezomib cytotoxicity in androgen-independent prostate cancer cell lines
    • Mikecin A-M, Walker LR, Kuna MRaucher D. Thermally targeted p21 peptide enhances bortezomib cytotoxicity in androgen-independent prostate cancer cell lines. Anticancer Drugs 2014;25(2):189-99
    • (2014) Anticancer Drugs , vol.25 , Issue.2 , pp. 189-199
    • Mikecin, A.-M.1    Walker, L.R.2
  • 81
    • 3042604470 scopus 로고    scopus 로고
    • Characterization of mutations and loss of heterozygosity of p53 and K-ras2 in pancreatic cancer cell lines by immobilized polymerase chain reaction
    • Butz J, Wickstrom E, Edwards J. Characterization of mutations and loss of heterozygosity of p53 and K-ras2 in pancreatic cancer cell lines by immobilized polymerase chain reaction. BMC Biotechnol 2003;3:11
    • (2003) BMC Biotechnol , vol.3 , pp. 11
    • Butz, J.1    Wickstrom, E.2    Edwards, J.3
  • 83
    • 84925273329 scopus 로고    scopus 로고
    • Available from [Cited 2011]
    • Medicine® USNLo. Spinocerebellar ataxia type 1. 2011. Available from: http://ghr.nlm.nih.gov/condition/ spinocerebellar-ataxia-type-1 [Cited 2011]
    • (2011) Spinocerebellar Ataxia Type 1
    • Medicine® USNLo1
  • 84
    • 67349176321 scopus 로고    scopus 로고
    • Glial S100B positive vacuoles in Purkinje cells: Earliest morphological abnormality in SCA1 transgenic mice
    • VIG PJ, LOPEZ ME, Jinrong W, et al. Glial S100B positive vacuoles in Purkinje cells: earliest morphological abnormality in SCA1 transgenic mice. J Neurol Sci Turish 2006;23(3):166
    • (2006) J Neurol Sci Turish , vol.23 , Issue.3 , pp. 166
    • Vig, P.J.1    Lopez, M.E.2    Jinrong, W.3
  • 85
    • 77649184659 scopus 로고    scopus 로고
    • Oxidative stress-enhanced SUMOylation and aggregation of ataxin-1: Implication of JNK pathway
    • Ryu J, Cho S, Park BC, Lee DH. Oxidative stress-enhanced SUMOylation and aggregation of ataxin-1: implication of JNK pathway. Biochem Biophys Res Commun 2010;393(2):280-5
    • (2010) Biochem Biophys Res Commun , vol.393 , Issue.2 , pp. 280-285
    • Ryu, J.1    Cho, S.2    Park, B.C.3    Lee, D.H.4
  • 86
    • 69549088145 scopus 로고    scopus 로고
    • Bergmann glial S100B activates myoinositol monophosphatase 1 and colocalizes to Purkinje cell vacuoles in SCA1 transgenic mice
    • Vig PJ, Shao Q, Subramony S, et al. Bergmann glial S100B activates myoinositol monophosphatase 1 and colocalizes to Purkinje cell vacuoles in SCA1 transgenic mice. The Cerebellum 2009;8(3):231-44
    • (2009) The Cerebellum , vol.8 , Issue.3 , pp. 231-244
    • Vig, P.J.1    Shao, Q.2    Subramony, S.3
  • 87
    • 10044230497 scopus 로고    scopus 로고
    • S100B-stimulated NO production by BV-2 microglia is independent of RAGE transducing activity but dependent on RAGE extracellular domain
    • Adami C, Bianchi R, Pula G, Donato R. S100B-stimulated NO production by BV-2 microglia is independent of RAGE transducing activity but dependent on RAGE extracellular domain. Biochimica et Biophysica Acta (BBA)- Molecular Cell Research 2004;1742(1):169-77
    • (2004) Biochimica et Biophysica Acta (BBA)-Molecular Cell Research , vol.1742 , Issue.1 , pp. 169-177
    • Adami, C.1    Bianchi, R.2    Pula, G.3    Donato, R.4
  • 88
    • 1842560240 scopus 로고    scopus 로고
    • S100B-mediated inhibition of the phosphorylation of GFAP is prevented by TRTK-12
    • Frizzo JK, Tramontina F, Bortoli E, et al. S100B-mediated inhibition of the phosphorylation of GFAP is prevented by TRTK-12. Neurochem Res 2004;29(4):735-40
    • (2004) Neurochem Res , vol.29 , Issue.4 , pp. 735-740
    • Frizzo, J.K.1    Tramontina, F.2    Bortoli, E.3
  • 89
    • 0029043797 scopus 로고
    • Characterization of S-100b binding epitopes. Identification of a novel target, the actin capping protein. CapZ
    • Ivanenkov VV, Jamieson GA, Gruenstein E, Dimlich RV. Characterization of S-100b binding epitopes. Identification of a novel target, the actin capping protein. CapZ. Journal of biological chemistry 1995;270(24):14651-8
    • (1995) Journal of biological chemistry , vol.270 , Issue.24 , pp. 14651-14658
    • Ivanenkov, V.V.1    Jamieson, G.A.2    Gruenstein, E.3    Dimlich, R.V.4
  • 90
    • 79960775251 scopus 로고    scopus 로고
    • Glial S100B protein modulates mutant ataxin- 1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy
    • Vig PJ, Hearst S, Shao Q, et al. Glial S100B protein modulates mutant ataxin- 1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy. The Cerebellum 2011;10(2):254-66
    • (2011) The Cerebellum , vol.10 , Issue.2 , pp. 254-266
    • Vig, P.J.1    Hearst, S.2    Shao, Q.3
  • 91
    • 34250620539 scopus 로고    scopus 로고
    • A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance
    • Bidwell GL III, Davis AN, Fokt I, et al. A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance. Invest New Drugs 2007;25(4):313-26
    • (2007) Invest New Drugs , vol.25 , Issue.4 , pp. 313-326
    • Bidwell, G.L.1    Davis, A.N.2    Fokt, I.3
  • 92
    • 33846510441 scopus 로고    scopus 로고
    • Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin
    • Bidwell GL III, Fokt I, Priebe W, Raucher D. Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin. Biochem Pharmacol 2007;73(5):620-31
    • (2007) Biochem Pharmacol , vol.73 , Issue.5 , pp. 620-631
    • Bidwell, G.L.1    Fokt, I.2    Priebe, W.3    Raucher, D.4
  • 93
    • 84865714324 scopus 로고    scopus 로고
    • Cell penetrating peptides fused to a thermally targeted biopolymer drug carrier improve the delivery and antitumor efficacy of an acid-sensitive doxorubicin derivative
    • Walker L, Perkins E, Kratz F, Raucher D. Cell penetrating peptides fused to a thermally targeted biopolymer drug carrier improve the delivery and antitumor efficacy of an acid-sensitive doxorubicin derivative. Int J Pharm 2012;436(1):825-32
    • (2012) Int J Pharm , vol.436 , Issue.1 , pp. 825-832
    • Walker, L.1    Perkins, E.2    Kratz, F.3    Raucher, D.4
  • 94
    • 84863803540 scopus 로고    scopus 로고
    • Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo
    • Moktan S, Perkins E, Kratz F, Raucher D. Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo. Mol Cancer Ther 2012;11(7):1547-56
    • (2012) Mol Cancer Ther , vol.11 , Issue.7 , pp. 1547-1556
    • Moktan, S.1    Perkins, E.2    Kratz, F.3    Raucher, D.4


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