Targeted drug delivery by thermally responsive polymers

Advanced Drug Delivery Reviews

Volumn 54, Issue 5, 2002, Pages 613-630

  Chilkoti, Ashutosh ^a   Dreher, Matthew R ^a   Meyer, Dan E ^a   Raucher, Drazen ^b  

^a Duke University   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Cancer therapy; Elastin like polypeptide; Hyperthermia; Lower critical solution temperature; pH controlled release; Poly(N isopropylacrylamide); Targeted drug delivery; Thermally responsive polymer; Tumor

Indexed keywords

CELL CULTURE; POLYMERS; POLYPEPTIDES; TOXICITY; TUMORS;

THERMAL TARGETING;

DRUG DOSAGE;

ANTINEOPLASTIC AGENT; DOXORUBICIN ELASTIN LIKE POLYPEPTIDE CONJUGATE; DRUG CARRIER; ELASTIN LIKE POLYPEPTIDE; POLY(N ISOPROPYLACRYLAMIDE CO ACRYLAMIDE); POLYMER; RADIOISOTOPE ELASTIN LIKE POLYPEPTIDE CONJUGATE; RHODAMINE POLYMER CONJUGATE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CELL CULTURE; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFICACY; DRUG HALF LIFE; DRUG PENETRATION; DRUG RETENTION; DRUG TARGETING; DRUG UPTAKE; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; HUMAN; HYPERTHERMIA; ISOTOPE LABELING; MACROMOLECULE; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; REVIEW; SOLID TUMOR; TEMPERATURE DEPENDENCE; THERMAL ANALYSIS; TUMOR CELL LINE; TUMOR LOCALIZATION;

ACRYLIC RESINS; ANIMALS; ANTINEOPLASTIC AGENTS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ELASTIN; FLUORESCENCE; HEATING; HUMANS; PEPTIDES; POLYMERS; TUMOR CELLS, CULTURED;

EID: 0037072528     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(02)00041-8     Document Type: Review

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