Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 11, 2015, Pages 3374-3379

  Deshmukh, Lalit ^a   Ghirlando, Rodolfo ^a   Clorea, G Marius ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

HIV 1 Gag; Interdomain motion; Proteolytic processing; Real time NMR; Residual dipolar couplings

Indexed keywords

GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; POLYPROTEIN; SINGLE STRANDED DNA; VIRUS DNA; DNA; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; DNA CLEAVAGE; DNA HAIRPIN; HETERONUCLEAR NUCLEAR MAGNETIC RESONANCE; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMATURE VIRUS; IONIC STRENGTH; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN NUCLEIC ACID INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; VIRUS CAPSID; VIRUS LIKE AGENT; VIRUS NUCLEOCAPSID; VIRUS RECOMBINANT; AMINO ACID SEQUENCE; BIOPHYSICS; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; STAINING; ULTRASTRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE;

AMINO ACID SEQUENCE; BIOPHYSICAL PHENOMENA; CAPSID; DNA; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV PROTEASE; HIV-1; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; NEGATIVE STAINING; PROTEIN STRUCTURE, SECONDARY; PROTEOLYSIS; RECOMBINANT PROTEINS;

EID: 84925250052     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501985112     Document Type: Article

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