Structure of the N-terminal 283-residue fragment of the immature HIV-1 Gag polyprotein

Nature Structural Biology

Volumn 9, Issue 7, 2002, Pages 537-543

  Tang, Chun ^a   Ndassa, Yasmine ^a   Summers, Michael F ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; GAG PROTEIN; VIRUS PROTEIN;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR STABILITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; VIRUS MORPHOLOGY;

AMINO ACID SEQUENCE; CYCLOPHILIN A; GENE PRODUCTS, GAG; HIV ANTIGENS; HIV-1; HYDROGEN BONDING; HYDROPHOBICITY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEOCAPSID PROTEINS; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS; VIRUS ASSEMBLY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0036294666     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb806     Document Type: Article

References (56)

1. Mass determination of Rous sarcoma virus virions by scaning transmission electron microscopy
2. Structural biology of HIV
3. Structure of the amino-terminal core domain of the HIV-1 capsid protein
4. Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid
5. Crystal structure of dimeric HIV-1 capsid protein
6. Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein
7. Structures of the HIV-1 capsid protein dimerization domain at 2.6 Å resolution
8. Head-to-tail dimers and interdomain flexibility revealed by the crystal structure of HIV-1 capsid protein (p24) complexed with a monoclonal antibody Fab
9. Structure and self-association of the Rous sarcoma virus capsid protein
10. Structural analysis of the N-terminal domain of the human T-cell leukemia virus capsid protein
11. Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly
12. N-terminal extension of human immunodeficiency virus capsid protein converts the in vitro assembly phenotype from tubular to spherical particles
13. Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type-1 before the initiation of reverse transcription
14. Specific incorporation of cyclophilin A into HIV-1 virions
15. HIV-1 uses host-cell proteins to form fully infectious virions
16. Human immunodeficiency virus type 1 gag protein binds to cyclophilins A and B
17. Functional association of cyclophilin A with HIV-1 virions
18. Cells with high cyclophilin A content support replication of Human Immunodeficiency Virus Type-1 Gag mutants with decreased ability to incorporate Cyclophilin A
19. Enzymatic recycling of clathrin from coated vesicles
20. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
21. Three-dimensional structure of the human immunodeficiency virus type 1 matrix protein
22. Crystal structures of the trimeric HIV-1 matrix protein: Implications for membrane association
23. Comparison of the NMR and X-ray structures of the HIV-1 matrix protein: Evidence for conformational changes during viral assembly
24. Properties of mouse leukemia viruses. III. Electron microscopic appearance as revealed after conventional preparation techniques as well as freezing-drying and freezing-etching
25. Localization of RNA tumor virus polypeptides I. Isolation of futher virus substructures
26. Cryo-electron microscopy reveals ordered domains in the immature HIV-particle
27. Organization of immature Human Immunodeficiency Virus Type 1
28. Further evidence for hexagonal organization of HIV gag protein in prebudding assemblies and immature virus-like particles
29. 2-terminal capsid domain: Structure determinants for proper core assembly and subsequent steps of early replication
30. Human immunodeficiency virus type-1 N-terminal capsid mutants that show aberrant core morphology and are blocked in initiation of reverse transcription in infected cells
31. Cryoelectron microscopy examination of human immunodeficiency virus type-1 virions with mutations in the cyclophilin A binding loop
32. Human Immunodeficiency Virus Type-1 replication is modulated by host cyclophilin A expression levels
33. Backbone dynamics of the N-terminal domain of the HIV-1 capsid protein and comparison with the G94D mutant conferring cyclosporin resistance/dependence
34. Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A
35. Human cyclophilin has a significantly higher affinity for HIV-1 recombinant p55 than p24
36. Molecular recognition in the HIV-1 capsid/cyclophilin A complex
37. Viral cell recognition and entry
38. 2O in protein NMR. Application to sensitivity enhancement and NOE measurement
39. Improved 3D triple-resonance NMR techniques applied to a 31 kDa protein
40. NMRPipe: A multidimensional spectral processing system based on UNIX pipes
41. NMRView: A computer program for the visualization and analysis for NMR data
42. Structures of larger proteins in solution: Three- and four-dimensional heteronuclear NMR spectroscopy
43. Methodological advances in protein NMR
44. The chemical shift index: A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
45. Protein backbone angle restraints from searching a database for chemical shift and sequence homology
46. Torsion angle dynamics for protein structure calculations with a new program, DYANA
47. Thornton PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
48. The MIDAS display system
49. Kraulis a program to produce both detailed and schematic plots of protein structures
50. Raster3D: Photorealistic molecular graphics
51. 15N inverse detected heteronuclear NMR spectroscopy: Application to staphylococcal nuclease
52. 15N-NMR relaxation measurements
53. 13Cα nuclear spin relaxation