The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles.

Retrovirology

Volumn 8, Issue , 2011, Pages 101-

  Nguyen, Albert T ^a   Feasley, Christa L ^b   Jackson, Ken W ^b   Nitz, Theodore J ^b   Salzwedel, Karl ^b   Air, Gillian M ^b   Sakalian, Michael ^b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

3-O-(3',3'-DIMETHYLSUCCINYL)BETULINIC ACID; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BEVIRIMAT; GAG PROTEIN; HIV GAG PROTEIN P25; SUCCINIC ACID DERIVATIVE; TRITERPENE;

ARTICLE; BINDING SITE; CELL LINE; CELL STRAIN HEK293; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; VIRUS ASSEMBLY; VIRUS REPLICATION;

ANTI-HIV AGENTS; BINDING SITES; CELL LINE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HEK293 CELLS; HIV INFECTIONS; HIV-1; HUMANS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SUCCINATES; TRITERPENES; VIRUS ASSEMBLY; VIRUS REPLICATION;

EID: 82755190460     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-8-101     Document Type: Article

References (0)