Mycobacterium tuberculosis-specific and MHC class I-restricted CD8+ T-cells exhibit a stem cell precursor-like phenotype in patients with active pulmonary tuberculosis

International Journal of Infectious Diseases

Volumn 32, Issue , 2015, Pages 13-22

  Axelsson Robertson, Rebecca ^a   Ju, Ji Hyeon ^b   Kim, Ho Youn ^b   Zumla, Alimuddin ^c   Maeurer, Markus ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b The Catholic University of Korea   (South Korea)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

CD8+ T cells; Mycobacterium tuberculosis; T cell differentiation; Tetramer

Indexed keywords

CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR7; FAS ANTIGEN; GAMMA INTERFERON; HLA A ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 7 RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; STEM CELL FACTOR RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL ANTIGEN; CYTOKINE; EPITOPE; HLA ANTIGEN CLASS 1;

ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; BLOOD SAMPLING; CD8+ T LYMPHOCYTE; CYTOKINE PRODUCTION; DEGRANULATION; EX VIVO STUDY; HUMAN; KOREAN (PEOPLE); LUNG TUBERCULOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE HOMING; MYCOBACTERIUM TUBERCULOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVIEW; STAINING; STEM CELL; TUBERCULOSIS; ADULT; AGED; FEMALE; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; YOUNG ADULT;

ADULT; AGED; ANTIGENS, BACTERIAL; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; EPITOPES, T-LYMPHOCYTE; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; STEM CELLS; TUBERCULOSIS, PULMONARY; YOUNG ADULT;

EID: 84925246593     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2014.12.017     Document Type: Review

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