The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model

Experimental Neurology

Volumn 265, Issue , 2015, Pages 8-21

  Geis, Christian ^a,b   Ritter, Christian ^a   Ruschil, Christoph ^a   Weishaupt, Andreas ^a   Grünewald, Benedikt ^a,b   Stoll, Guido ^a   Holmoy, Trygve ^c   Misu, Tatsuro ^d   Fujihara, Kazuo ^d   Hemmer, Bernhard ^e,h   Stadelmann, Christine ^f   Bennett, Jeffrey L ^g   Sommer, Claudia ^a   Toyka, Klaus V ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

^c AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f Technische Universität München Munich Cluster for Systems Neurology   (Germany)

^g UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^h UNIVERSITY OF COLORADO   (United States)

Author keywords

Aquaporin 4; Astrocyte; EAAT2; Intrathecal passive transfer; Neuromyelitis optica; NMDA receptor

Indexed keywords

AQUAPORIN 4; AUTOANTIBODY; EXCITATORY AMINO ACID TRANSPORTER 2; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOGLOBULIN G; MYELIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; AQP4 PROTEIN, RAT;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN REGION; CELL DAMAGE; CELL INFILTRATION; CELL LOSS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; EVOKED SOMATOSENSORY RESPONSE; FEMALE; GRAY MATTER; HISTOLOGY; HISTOPATHOLOGY; IMAGE ANALYSIS; IMMUNOGLOBULIN DEPOSITION; IMMUNOREACTIVITY; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NERVE FIBER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPINAL CORD DISEASE; WHITE MATTER; ANIMAL; DISEASE MODEL; HUMAN; IMMUNOLOGY; INTRASPINAL DRUG ADMINISTRATION; LEWIS RAT; NEUROMYELITIS OPTICA; PASSIVE IMMUNIZATION; PATHOLOGY; PROCEDURES; SPINAL CORD DISEASES;

ANIMALS; AQUAPORIN 4; AUTOANTIBODIES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMUNIZATION, PASSIVE; INJECTIONS, SPINAL; NEUROMYELITIS OPTICA; RATS; RATS, INBRED LEW; SPINAL CORD DISEASES;

EID: 84925242478     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.12.015     Document Type: Article

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