Complex regulation of PKCβ2 and PDK-1/AKT by ROCK2 in diabetic heart

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Lin, Guorong ^a   Brownsey, Roger W ^a   MacLeod, Kathleen M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER 4; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; RHO KINASE; ROCK2 PROTEIN, RAT; SLC2A4 PROTEIN, RAT;

ADULT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; HEART FUNCTION; HEART MUSCLE CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MALE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; STOMACH MUSCLE; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; EXPERIMENTAL DIABETES MELLITUS; GENETICS; HEART MUSCLE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; RNA INTERFERENCE; WISTAR RAT;

ANIMALS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TRANSPORTER TYPE 4; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN INTERACTION MAPS; PROTEIN KINASE C BETA; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84925226167     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086520     Document Type: Article

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