Regulation of muscle creatine kinase by phosphorylation in normal and diabetic hearts

Cellular and Molecular Life Sciences

Volumn 66, Issue 1, 2009, Pages 135-144

  Lin, G ^a   Liu, Y ^a   MacLeod, K M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

ATP; Muscle creatine kinase; Phosphocreatine; Phosphorylation; PKC isoform

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE KINASE MM; CREATINE PHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE 2; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE 2C; SERINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HEART MUSCLE; IMMUNOPRECIPITATION; MALE; NONHUMAN; RAT; TANDEM MASS SPECTROMETRY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CREATINE KINASE, MM FORM; DIABETES MELLITUS, EXPERIMENTAL; MALE; MUSCLE, SKELETAL; MYOCARDIUM; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; RATS; RATS, WISTAR; SERINE; TANDEM MASS SPECTROMETRY;

EID: 58149522335     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-008-8575-3     Document Type: Article

References (32)

1. McLeish, M. J. and Kenyon, G. L. (2005) Relating structure to mechanism in creatine kinase. Crit. Rev. Biochem. Mol. Biol. 40, 1-20
2. Wallimann, T., Dolder, M., Schlattner, U., Eder, M., Hornemann, T., O'Gorman, E., Ruck, A. and Brdiczka, D. (1998) Some new aspects of creatine kinase (CK): Compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology. Biofactors 8, 229-234
3. Quest, A. F., Soldati, T., Hemmer, W., Perriard, J. C., Eppenberger, H. M. and Wallimann, T. (1990) Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivo. FEBS Lett. 269, 457-464
4. Chida, K., Kasahara, K., Tsunenaga, M., Kohno, Y., Yamada, S., Ohmi, S. and Kuroki, T. (1990) Purification and identification of creatine phosphokinase B as a substrate of protein kinase C in mouse skin in vivo. Biochem. Biophys. Res. Commun. 173, 351-357
5. Chida, K., Tsunenaga, M., Kasahara, K., Kohno, Y. and Kuroki, T. (1990) Regulation of creatine phosphokinase B activity by protein kinase C. Biochem. Biophys. Res. Commun. 173, 346-350
6. Ponticos, M., Lu, Q. L., Morgan, J. E., Hardie, D. G., Partridge, T. A. and Carling, D. (1998) Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle. EMBO. J. 17, 1688-1699
7. Abnous, K. and Storey, K. B. (2007) Regulation of skeletal muscle creatine kinase from a hibernating mammal. Arch. Biochem. Biophys. 467, 10-19
8. Shen, W., Spindler, M., Higgins, M. A., Jin, N., Gill, R. M., Bloem, L. J., Ryan, T. P. and Ingwall, J. S. (2005) The fall in creatine levels and creatine kinase isozyme changes in the failing heart are reversible: Complex post-transcriptional regulation of the components of the CK system. J. Mol. Cell. Cardiol. 39, 537-544
9. Taegtmeyer, H., McNulty, P. and Young, M. E. (2002) Adaptation and maladaptation of the heart in diabetes. I. General concepts. Circulation 105, 1727-1733
10. Young, M. E., McNulty, P. and Taegtmeyer, H. (2002) Adaptation and maladaptation of the heart in diabetes. II. potential mechanisms. Circulation 105, 1861-1870
11. Inoguchi, T., Battan, R., Handler, E., Sportsman, J. R., Heath, W. and King, G. L. (1992) Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation. Proc. Natl. Acad. Sci. USA 89, 11059-11063
12. Ishii, H., Koya, D. and King, G. L. (1998) Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus. J. Mol. Med. 76, 21-31
13. Aiello L. P, Bursell S. E., Clermont A., Duh E., Ishii H., Takagi C., Mori F., Ciulla T. A., Ways K., Jirousek M., Smith L. E. and King G. L. (1997) Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes 46, 1473-1480
14. Babazono, T., Kapor-Drezgic, J., Dlugosz, J. A. and Whiteside, C. (1998) Altered expression and subcellular localization of diacylglycerol-sensitive protein kinase C isoforms in diabetic rat glomerular cells. Diabetes 47, 668-676
15. Koya, D., Jirousek, M. R., Lin, Y. W., Ishii, H., Kuboki, K. and King, G. L. (1997) Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats. J. Clin. Invest. 100, 115-126
16. Shiba, T., Inoguchi, T., Sportsman, J. R., Heath, W. F., Bursell, S. and King, G. L. (1993) Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation. Am. J. Physiol. 265, E783-793
17. Malhotra, A., Reich, D., Reich, D., Nakouzi, A., Sanghi, V., Geenen, D. L. and Buttrick, P. M. (1997) Experimental diabetes is associated with functional activation of protein kinase C epsilon and phosphorylation of troponin I in the heart, which are prevented by angiotensin II receptor blockade. Circ. Res. 81, 1027-1033
18. Tanzer, M. L. and Gilvarg, C. (1959) Creatine and creatine kinase measurement. J. Biol. Chem. 234, 3201-3204
19. Oliver, I. T. (1955) A spectrophotometric method for the determination of creatine phosphokinase and myokinase. Biochem. J. 61, 116-122
20. Rosalki, S. B. (1967) An improved procedure for serum creatine phosphokinase determination. J. Lab. Clin. Med. 69, 696-705
21. Lin, G., Craig, G. P., Zhang, L., Yuen, V. G., Allard, M., McNeill, J. H. and MacLeod, K. M. (2007) Acute inhibition of Rho-kinase improves cardiac contractile function in streptozotocin-diabetic rats. Cardiovasc. Res. 75, 51-58
22. Blom, N., Sicheritz-Ponten, T., Gupta, R., Gammeltoft, S. and Brunak, S. (2004) Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 4, 1633-1649
23. Gannon, J., Staunton, L., O'Connell, K., Doran, P. and Ohlendieck, K. (2008) Phosphoproteomic analysis of aged skeletal muscle. Int. J. Mol. Med. 22, 33-42
24. Stolz, M., Hornemann, T., Schlattner, U. and Wallimann, T. (2002) Mutation of conserved active-site threonine residues in creatine kinase affects autophosphorylation and enzyme kinetics. Biochem. J. 363, 785-792
25. Iyengar, M. R. (1984) Creatine kinase as an intracellular regulator. J. Muscle Res. Cell Motil. 5, 527-534
26. Popovich, B. K., Boheler, K. R. and Dillmann, W. H. (1989) Diabetes decreases creatine kinase enzyme activity and mRNA level in the rat heart. Am. J. Physiol. 257, E573-577
27. Somjen, D., Shen, M., Stern, N. and Mirsky, N. (2006) Diabetes modulates differentially creatine kinase-specific activity responsiveness to estradiol-17beta and to raloxifene in rat organs. J. Cell. Biochem. 99, 133-139
28. Matsumoto, Y., Kaneko, M., Kobayashi, A., Fujise, Y. and Yamazaki, N. (1995) Creatine kinase kinetics in diabetic cardiomyopathy. Am. J. Physiol. 268, E1070-1076
29. Spindler, M., Saupe, K. W., Tian, R., Ahmed, S., Matlib, M. A. and Ingwall, J. S. (1999) Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A(31)P NMR magnetization transfer study of the intact beating rat heart. J. Mol. Cell. Cardiol. 31, 2175-2189
30. Rastogi, S., Sentex, E., Elimban, V., Dhalla, N. S. and Netticadan, T. (2003) Elevated levels of protein phosphatase 1 and phosphatase 2A may contribute to cardiac dysfunction in diabetes. Biochim. Biophys. Acta 1638, 273-277
31. Jenkins, R. L., McDaniel, H. G., Digerness, S., Parrish, S. W. and Ong, R. L. (1988) Adenine nucleotide metabolism in hearts of diabetic rats. Comparison to diaphragm, liver, and kidney. Diabetes 37, 629-636
32. Ingwall, J. S. (2002) Is creatine kinase a target for AMP-activated protein kinase in the heart? J. Mol. Cell. Cardiol. 34, 1111-1120