Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats

Cardiovascular Diabetology

Volumn 8, Issue , 2009, Pages

  Failli, Paola ^a   Alfarano, Chiara ^a   Franchi Micheli, Sergio ^a   Mannucci, Edoardo ^a   Cerbai, Elisabetta ^a   Mugelli, Alessandro ^a   Raimondi, Laura ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN II; CITRIC ACID; DRINKING WATER; FASUDIL; GLUCOSE; IRBESARTAN; LOSARTAN; PHENYLEPHRINE; RHO KINASE; STREPTOZOCIN; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; BIPHENYL DERIVATIVE; DRUG DERIVATIVE; ROCK1 PROTEIN, HUMAN; TETRAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IN VIVO STUDY; MALE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; UPREGULATION; WISTAR RAT; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; THORACIC AORTA; VASOCONSTRICTION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANGIOTENSIN II; ANIMALS; AORTA, THORACIC; BIPHENYL COMPOUNDS; DIABETES MELLITUS, EXPERIMENTAL; LOSARTAN; MALE; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; TETRAZOLES; UP-REGULATION; VASOCONSTRICTION;

EID: 67651177684     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-8-32     Document Type: Article

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