-
1
-
-
84905376126
-
DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe
-
Ashley A.K., Shrivastav M., Nie J., Amerin C., Troksa K., Glanzer J.G., Liu S., Opiyo S.O., Dimitrova D.D., Le P., et al. DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe. DNA Repair (Amst.) 2014, 21:131-139.
-
(2014)
DNA Repair (Amst.)
, vol.21
, pp. 131-139
-
-
Ashley, A.K.1
Shrivastav, M.2
Nie, J.3
Amerin, C.4
Troksa, K.5
Glanzer, J.G.6
Liu, S.7
Opiyo, S.O.8
Dimitrova, D.D.9
Le, P.10
-
2
-
-
67649862225
-
Replication fork reversal and the maintenance of genome stability
-
Atkinson J., McGlynn P. Replication fork reversal and the maintenance of genome stability. Nucleic Acids Res. 2009, 37:3475-3492.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 3475-3492
-
-
Atkinson, J.1
McGlynn, P.2
-
3
-
-
77649165394
-
Maintaining genome stability at the replication fork
-
Branzei D., Foiani M. Maintaining genome stability at the replication fork. Nat. Rev. Mol. Cell Biol. 2010, 11:208-219.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 208-219
-
-
Branzei, D.1
Foiani, M.2
-
4
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting S.F., Callén E., Wong N., Chen H.T., Polato F., Gunn A., Bothmer A., Feldhahn N., Fernandez-Capetillo O., Cao L., et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010, 141:243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callén, E.2
Wong, N.3
Chen, H.T.4
Polato, F.5
Gunn, A.6
Bothmer, A.7
Feldhahn, N.8
Fernandez-Capetillo, O.9
Cao, L.10
-
5
-
-
78649336706
-
The DNA damage response: making it safe to play with knives
-
Ciccia A., Elledge S.J. The DNA damage response: making it safe to play with knives. Mol. Cell 2010, 40:179-204.
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
6
-
-
47749141560
-
ATR: an essential regulator of genome integrity
-
Cimprich K.A., Cortez D. ATR: an essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol. 2008, 9:616-627.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
7
-
-
84880440332
-
ATR phosphorylates SMARCAL1 to prevent replication fork collapse
-
Couch F.B., Bansbach C.E., Driscoll R., Luzwick J.W., Glick G.G., Bétous R., Carroll C.M., Jung S.Y., Qin J., Cimprich K.A., Cortez D. ATR phosphorylates SMARCAL1 to prevent replication fork collapse. Genes Dev. 2013, 27:1610-1623.
-
(2013)
Genes Dev.
, vol.27
, pp. 1610-1623
-
-
Couch, F.B.1
Bansbach, C.E.2
Driscoll, R.3
Luzwick, J.W.4
Glick, G.G.5
Bétous, R.6
Carroll, C.M.7
Jung, S.Y.8
Qin, J.9
Cimprich, K.A.10
Cortez, D.11
-
8
-
-
69949166903
-
Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities
-
Fugger K., Mistrik M., Danielsen J.R., Dinant C., Falck J., Bartek J., Lukas J., Mailand N. Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities. J.Cell Biol. 2009, 186:655-663.
-
(2009)
J.Cell Biol.
, vol.186
, pp. 655-663
-
-
Fugger, K.1
Mistrik, M.2
Danielsen, J.R.3
Dinant, C.4
Falck, J.5
Bartek, J.6
Lukas, J.7
Mailand, N.8
-
9
-
-
84877155835
-
FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress
-
Fugger K., Chu W.K., Haahr P., Kousholt A.N., Beck H., Payne M.J., Hanada K., Hickson I.D., Sørensen C.S. FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress. Nat. Commun. 2013, 4:1423.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1423
-
-
Fugger, K.1
Chu, W.K.2
Haahr, P.3
Kousholt, A.N.4
Beck, H.5
Payne, M.J.6
Hanada, K.7
Hickson, I.D.8
Sørensen, C.S.9
-
10
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis T.D., Gorgoulis V.G., Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008, 319:1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
11
-
-
35848930133
-
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
-
Hanada K., Budzowska M., Davies S.L., van Drunen E., Onizawa H., Beverloo H.B., Maas A., Essers J., Hickson I.D., Kanaar R. The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nat. Struct. Mol. Biol. 2007, 14:1096-1104.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1096-1104
-
-
Hanada, K.1
Budzowska, M.2
Davies, S.L.3
van Drunen, E.4
Onizawa, H.5
Beverloo, H.B.6
Maas, A.7
Essers, J.8
Hickson, I.D.9
Kanaar, R.10
-
12
-
-
79955490586
-
Replication stress induces 53BP1-containing OPT domains in G1 cells
-
Harrigan J.A., Belotserkovskaya R., Coates J., Dimitrova D.S., Polo S.E., Bradshaw C.R., Fraser P., Jackson S.P. Replication stress induces 53BP1-containing OPT domains in G1 cells. J.Cell Biol. 2011, 193:97-108.
-
(2011)
J.Cell Biol.
, vol.193
, pp. 97-108
-
-
Harrigan, J.A.1
Belotserkovskaya, R.2
Coates, J.3
Dimitrova, D.S.4
Polo, S.E.5
Bradshaw, C.R.6
Fraser, P.7
Jackson, S.P.8
-
13
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson I., Zhao Y., Richardson C.J., Green S.J., Martin N.M., Orr A.I., Reaper P.M., Jackson S.P., Curtin N.J., Smith G.C. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res. 2004, 64:9152-9159.
-
(2004)
Cancer Res.
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.10
-
14
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
15
-
-
84875892495
-
FBH1 protects melanocytes from transformation and is deregulated in melanomas
-
Jeong Y.T., Cermak L., Guijarro M.V., Hernando E., Pagano M. FBH1 protects melanocytes from transformation and is deregulated in melanomas. Cell Cycle 2013, 12:1128-1132.
-
(2013)
Cell Cycle
, vol.12
, pp. 1128-1132
-
-
Jeong, Y.T.1
Cermak, L.2
Guijarro, M.V.3
Hernando, E.4
Pagano, M.5
-
16
-
-
84873042958
-
FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress
-
Jeong Y.T., Rossi M., Cermak L., Saraf A., Florens L., Washburn M.P., Sung P., Schildkraut C.L., Pagano M. FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. J.Cell Biol. 2013, 200:141-149.
-
(2013)
J.Cell Biol.
, vol.200
, pp. 141-149
-
-
Jeong, Y.T.1
Rossi, M.2
Cermak, L.3
Saraf, A.4
Florens, L.5
Washburn, M.P.6
Sung, P.7
Schildkraut, C.L.8
Pagano, M.9
-
17
-
-
0037025380
-
The novel human DNA helicase hFBH1 is an F-box protein
-
Kim J., Kim J.H., Lee S.H., Kim D.H., Kang H.Y., Bae S.H., Pan Z.Q., Seo Y.S. The novel human DNA helicase hFBH1 is an F-box protein. J.Biol. Chem. 2002, 277:24530-24537.
-
(2002)
J.Biol. Chem.
, vol.277
, pp. 24530-24537
-
-
Kim, J.1
Kim, J.H.2
Lee, S.H.3
Kim, D.H.4
Kang, H.Y.5
Bae, S.H.6
Pan, Z.Q.7
Seo, Y.S.8
-
18
-
-
77952581198
-
Mammalian Fbh1 is important to restore normal mitotic progression following decatenation stress
-
Laulier C., Cheng A., Huang N., Stark J.M. Mammalian Fbh1 is important to restore normal mitotic progression following decatenation stress. DNA Repair (Amst.) 2010, 9:708-717.
-
(2010)
DNA Repair (Amst.)
, vol.9
, pp. 708-717
-
-
Laulier, C.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
19
-
-
0034644220
-
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
-
Li S., Ting N.S., Zheng L., Chen P.L., Ziv Y., Shiloh Y., Lee E.Y., Lee W.H. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 2000, 406:210-215.
-
(2000)
Nature
, vol.406
, pp. 210-215
-
-
Li, S.1
Ting, N.S.2
Zheng, L.3
Chen, P.L.4
Ziv, Y.5
Shiloh, Y.6
Lee, E.Y.7
Lee, W.H.8
-
20
-
-
79959488298
-
DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange
-
Liaw H., Lee D., Myung K. DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. PLoS ONE 2011, 6:e21424.
-
(2011)
PLoS ONE
, vol.6
, pp. e21424
-
-
Liaw, H.1
Lee, D.2
Myung, K.3
-
21
-
-
68849127270
-
Fbh1 limits Rad51-dependent recombination at blocked replication forks
-
Lorenz A., Osman F., Folkyte V., Sofueva S., Whitby M.C. Fbh1 limits Rad51-dependent recombination at blocked replication forks. Mol. Cell. Biol. 2009, 29:4742-4756.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4742-4756
-
-
Lorenz, A.1
Osman, F.2
Folkyte, V.3
Sofueva, S.4
Whitby, M.C.5
-
22
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas C., Savic V., Bekker-Jensen S., Doil C., Neumann B., Pedersen R.S., Grøfte M., Chan K.L., Hickson I.D., Bartek J., Lukas J. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat. Cell Biol. 2011, 13:243-253.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grøfte, M.7
Chan, K.L.8
Hickson, I.D.9
Bartek, J.10
Lukas, J.11
-
23
-
-
84876021636
-
Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase
-
Masuda-Ozawa T., Hoang T., Seo Y.S., Chen L.F., Spies M. Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase. Nucleic Acids Res. 2013, 41:3576-3587.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 3576-3587
-
-
Masuda-Ozawa, T.1
Hoang, T.2
Seo, Y.S.3
Chen, L.F.4
Spies, M.5
-
24
-
-
84876333995
-
Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates
-
Neelsen K.J., Zanini I.M., Herrador R., Lopes M. Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates. J.Cell Biol. 2013, 200:699-708.
-
(2013)
J.Cell Biol.
, vol.200
, pp. 699-708
-
-
Neelsen, K.J.1
Zanini, I.M.2
Herrador, R.3
Lopes, M.4
-
25
-
-
84888788310
-
Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template
-
Neelsen K.J., Zanini I.M., Mijic S., Herrador R., Zellweger R., Ray Chaudhuri A., Creavin K.D., Blow J.J., Lopes M. Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template. Genes Dev. 2013, 27:2537-2542.
-
(2013)
Genes Dev.
, vol.27
, pp. 2537-2542
-
-
Neelsen, K.J.1
Zanini, I.M.2
Mijic, S.3
Herrador, R.4
Zellweger, R.5
Ray Chaudhuri, A.6
Creavin, K.D.7
Blow, J.J.8
Lopes, M.9
-
26
-
-
84888816884
-
Visualization and interpretation of eukaryotic DNA replication intermediates invivo by electron microscopy
-
Neelsen K.J., Chaudhuri A.R., Follonier C., Herrador R., Lopes M. Visualization and interpretation of eukaryotic DNA replication intermediates invivo by electron microscopy. Methods Mol. Biol. 2014, 1094:177-208.
-
(2014)
Methods Mol. Biol.
, vol.1094
, pp. 177-208
-
-
Neelsen, K.J.1
Chaudhuri, A.R.2
Follonier, C.3
Herrador, R.4
Lopes, M.5
-
27
-
-
76849109722
-
Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair
-
Petermann E., Orta M.L., Issaeva N., Schultz N., Helleday T. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol. Cell 2010, 37:492-502.
-
(2010)
Mol. Cell
, vol.37
, pp. 492-502
-
-
Petermann, E.1
Orta, M.L.2
Issaeva, N.3
Schultz, N.4
Helleday, T.5
-
28
-
-
33747352774
-
The Bloom's syndrome helicase can promote the regression of a model replication fork
-
Ralf C., Hickson I.D., Wu L. The Bloom's syndrome helicase can promote the regression of a model replication fork. J.Biol. Chem. 2006, 281:22839-22846.
-
(2006)
J.Biol. Chem.
, vol.281
, pp. 22839-22846
-
-
Ralf, C.1
Hickson, I.D.2
Wu, L.3
-
29
-
-
84861322877
-
Topoisomerase I poisoning results in PARP-mediated replication fork reversal
-
Ray Chaudhuri A., Hashimoto Y., Herrador R., Neelsen K.J., Fachinetti D., Bermejo R., Cocito A., Costanzo V., Lopes M. Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nat. Struct. Mol. Biol. 2012, 19:417-423.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 417-423
-
-
Ray Chaudhuri, A.1
Hashimoto, Y.2
Herrador, R.3
Neelsen, K.J.4
Fachinetti, D.5
Bermejo, R.6
Cocito, A.7
Costanzo, V.8
Lopes, M.9
-
30
-
-
0025812689
-
Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
-
Ryan A.J., Squires S., Strutt H.L., Johnson R.T. Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res. 1991, 19:3295-3300.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 3295-3300
-
-
Ryan, A.J.1
Squires, S.2
Strutt, H.L.3
Johnson, R.T.4
-
31
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori A.A., Lukas C., Coates J., Mistrik M., Fu S., Bartek J., Baer R., Lukas J., Jackson S.P. Human CtIP promotes DNA end resection. Nature 2007, 450:509-514.
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
32
-
-
84888362110
-
FBH1 helicase disrupts RAD51 filaments invitro and modulates homologous recombination in mammalian cells
-
Simandlova J., Zagelbaum J., Payne M.J., Chu W.K., Shevelev I., Hanada K., Chatterjee S., Reid D.A., Liu Y., Janscak P., et al. FBH1 helicase disrupts RAD51 filaments invitro and modulates homologous recombination in mammalian cells. J.Biol. Chem. 2013, 288:34168-34180.
-
(2013)
J.Biol. Chem.
, vol.288
, pp. 34168-34180
-
-
Simandlova, J.1
Zagelbaum, J.2
Payne, M.J.3
Chu, W.K.4
Shevelev, I.5
Hanada, K.6
Chatterjee, S.7
Reid, D.A.8
Liu, Y.9
Janscak, P.10
-
33
-
-
84865620494
-
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography
-
Thompson L.H. Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography. Mutat. Res. 2012, 751:158-246.
-
(2012)
Mutat. Res.
, vol.751
, pp. 158-246
-
-
Thompson, L.H.1
|