The bipartite Rac1 guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (Elmo1/Dock180) protects endothelial cells from apoptosis in blood vessel development

Journal of Biological Chemistry

Volumn 290, Issue 10, 2015, Pages 6408-6418

  Schäker, Kathrin ^a,c   Bartsch, Susanne ^a   Patry, Christian ^a   Stoll, Sandra J ^a   Hillebrands, Jan Luuk ^d   Wieland, Thomas ^b   Kroll, Jens ^a,c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MEDICAL FACULTY MANNHEIM HEIDELBERG UNIVERSITY   (Germany)

^c GERMAN CANCER RESEARCH CENTER   (Germany)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CELL DEATH; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; ENDOTHELIAL CELLS; ENZYMES; NUCLEOTIDES; POSITIVE IONS;

ENDOTHELIAL FUNCTION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; P-21 ACTIVATED KINASE; PROTECTIVE EFFECTS; VASCULAR DEVELOPMENT; VASCULAR FUNCTIONS; VESSEL DEVELOPMENT; ZEBRAFISH DEVELOPMENT;

CELL SIGNALING;

CASPASE 3; CASPASE 7; DEDICATOR OF CYTOKINESIS 180 PROTEIN; ENGULFMENT AND CELL MOTILITY 1 PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LIPOCORTIN 5; P21 ACTIVATED KINASE; PROTEIN KINASE B; RAC1 PROTEIN; UNCLASSIFIED DRUG; DOCK1 PROTEIN, HUMAN; ELMO1 PROTEIN, HUMAN; RAC PROTEIN; RAC1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL COUNT; CELL PROTECTION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; ZEBRA FISH; ANIMAL; BIOSYNTHESIS; BLOOD VESSEL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

DANIO RERIO;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; BLOOD VESSELS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; ZEBRAFISH;

EID: 84925004056     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.633701     Document Type: Article

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