The activation of RhoC in vascular endothelial cells is required for the S1P receptor type 2-induced inhibition of angiogenesis

Cellular Signalling

Volumn 25, Issue 12, 2013, Pages 2478-2484

  Del Galdo, Sabrina ^a   Vettel, Christiane ^a,b   Heringdorf, Dagmar Meyer zu ^c   Wieland, Thomas ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Angiogenesis; Leukemia associated Rho guanine nucleotide exchange factor; RhoC; RhoGTPases; Sphingosine 1 phosphate

Indexed keywords

LEUKEMIA ASSOCIATED RHO SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN RHOC; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; UNCLASSIFIED DRUG; VASCULOTROPIN; ARHGEF12 PROTEIN, HUMAN; LYSOPHOSPHOLIPID; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHOC PROTEIN, HUMAN; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ADENOVIRUS; ANTIANGIOGENIC ACTIVITY; ARTICLE; AUTOCRINE EFFECT; CELL ISOLATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IN VITRO STUDY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; VIRUS RECOMBINANT; ANALOGS AND DERIVATIVES; ANGIOGENESIS; CYTOLOGY; METABOLISM;

HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LYSOPHOSPHOLIPIDS; NEOVASCULARIZATION, PHYSIOLOGIC; RAC1 GTP-BINDING PROTEIN; RECEPTORS, LYSOSPHINGOLIPID; RHO GTP-BINDING PROTEINS; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 84884166537     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.08.017     Document Type: Article

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