-
2
-
-
0031466232
-
The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells
-
Kroll J, Waltenberger J. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem. 1997;272:32521-32527.
-
(1997)
J Biol Chem
, vol.272
, pp. 32521-32527
-
-
Kroll, J.1
Waltenberger, J.2
-
3
-
-
0032573554
-
VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2 (KDR)
-
Kroll J, Waltenberger J. VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2 (KDR). Biochem Biophys Res Commun. 1998;252:743-746.
-
(1998)
Biochem Biophys Res Commun
, vol.252
, pp. 743-746
-
-
Kroll, J.1
Waltenberger, J.2
-
4
-
-
0033619780
-
A novel function of VEGF receptor-2 (KDR): Rapid release of nitric oxide in response to VEGF-A stimulation in endothelial cells
-
Kroll J, Waltenberger J. A novel function of VEGF receptor-2 (KDR): rapid release of nitric oxide in response to VEGF-A stimulation in endothelial cells. Biochem Biophys Res Commun. 1999;265:636-639.
-
(1999)
Biochem Biophys Res Commun
, vol.265
, pp. 636-639
-
-
Kroll, J.1
Waltenberger, J.2
-
5
-
-
0030831104
-
A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis
-
Shalaby F, Ho J, Stanford WL, Fischer KD, Schuh AC, Schwartz L, Bernstein A, Rossant J. A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell. 1997;89:981-990.
-
(1997)
Cell
, vol.89
, pp. 981-990
-
-
Shalaby, F.1
Ho, J.2
Stanford, W.L.3
Fischer, K.D.4
Schuh, A.C.5
Schwartz, L.6
Bernstein, A.7
Rossant, J.8
-
6
-
-
0030734010
-
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
Rousseau S, Houle F, Landry J, Huot J. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene. 1997;15:2169-2177.
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rousseau, S.1
Houle, F.2
Landry, J.3
Huot, J.4
-
7
-
-
0027997863
-
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
-
Waltenberger J, Claesson-Welsh L, Siegbahn A, Shibuya M, Heldin CH. Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem. 1994;269:26988-26995.
-
(1994)
J Biol Chem
, vol.269
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
Shibuya, M.4
Heldin, C.H.5
-
8
-
-
0034724736
-
Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt
-
Morales-Ruiz M, Fulton D, Sowa G, Languino LR, Fujio Y, Walsh K, Sessa WC. Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ Res. 2000;86:892-896.
-
(2000)
Circ Res
, vol.86
, pp. 892-896
-
-
Morales-Ruiz, M.1
Fulton, D.2
Sowa, G.3
Languino, L.R.4
Fujio, Y.5
Walsh, K.6
Sessa, W.C.7
-
9
-
-
0037349385
-
Versatile inducible activation system of Akt/PKB signaling pathway in mice
-
Kroll J, Cobo P, Sato TN. Versatile inducible activation system of Akt/PKB signaling pathway in mice. Genesis. 2003;35:160-163.
-
(2003)
Genesis
, vol.35
, pp. 160-163
-
-
Kroll, J.1
Cobo, P.2
Sato, T.N.3
-
10
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature. 1999;399:601-605.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
11
-
-
1242296871
-
Rho activity critically and selectively regulates endothelial cell organization during angiogenesis
-
Hoang MV, Whelan MC, Senger DR. Rho activity critically and selectively regulates endothelial cell organization during angiogenesis. Proc Natl Acad Sci U S A. 2004;101:1874-1879.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1874-1879
-
-
Hoang, M.V.1
Whelan, M.C.2
Senger, D.R.3
-
12
-
-
0942275690
-
KDR stimulates endothelial cell migration through heterotrimeric G protein Gq/11-mediated activation of a small GTPase RhoA
-
Zeng H, Zhao D, Mukhopadhyay D. KDR stimulates endothelial cell migration through heterotrimeric G protein Gq/11-mediated activation of a small GTPase RhoA. J Biol Chem. 2002;277:46791-46798.
-
(2002)
J Biol Chem
, vol.277
, pp. 46791-46798
-
-
Zeng, H.1
Zhao, D.2
Mukhopadhyay, D.3
-
13
-
-
0033961690
-
The kelch repeat superfamily of proteins: Propellers of cell function
-
Adams J, Kelso R, Cooley L. The kelch repeat superfamily of proteins: propellers of cell function. Trends Cell Biol. 2000;10:17-24.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 17-24
-
-
Adams, J.1
Kelso, R.2
Cooley, L.3
-
14
-
-
0027403024
-
kelch encodes a component of intercellular bridges in Drosophila egg chambers
-
Xue F, Cooley L. kelch encodes a component of intercellular bridges in Drosophila egg chambers. Cell. 1993;72:681-693.
-
(1993)
Cell
, vol.72
, pp. 681-693
-
-
Xue, F.1
Cooley, L.2
-
15
-
-
8544277232
-
The BACK domain in BTB-kelch proteins
-
Stogios PJ, Prive GG. The BACK domain in BTB-kelch proteins. Trends Biochem Sci. 2004;29:634-637.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 634-637
-
-
Stogios, P.J.1
Prive, G.G.2
-
16
-
-
0141750416
-
-
Geyer R, Wee S, Anderson S, Yates J, Wolf DA. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol Cell. 2003;12:783-790.
-
Geyer R, Wee S, Anderson S, Yates J, Wolf DA. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol Cell. 2003;12:783-790.
-
-
-
-
17
-
-
33646186366
-
The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis
-
Nacak TG, Leptien K, Fellner D, Augustin HG, Kroll J. The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis. J Biol Chem. 2006;281:5065-5071.
-
(2006)
J Biol Chem
, vol.281
, pp. 5065-5071
-
-
Nacak, T.G.1
Leptien, K.2
Fellner, D.3
Augustin, H.G.4
Kroll, J.5
-
18
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H, Noda S, Takahashi S, Imakado S, Kotsuji T, Otsuka F, Roop DR, Harada T, Engel JD, Yamamoto M. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet. 2003;35:238-245.
-
(2003)
Nat Genet
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
Harada, T.11
Engel, J.D.12
Yamamoto, M.13
-
19
-
-
25444513655
-
The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation
-
Kroll J, Shi X, Caprioli A, Liu HH, Waskow C, Lin KM, Miyazaki T, Rodewald HR, Sato TN. The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation. Mol Cell Biol. 2005;25:8531-8540.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8531-8540
-
-
Kroll, J.1
Shi, X.2
Caprioli, A.3
Liu, H.H.4
Waskow, C.5
Lin, K.M.6
Miyazaki, T.7
Rodewald, H.R.8
Sato, T.N.9
-
20
-
-
2442675385
-
Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice
-
Yan W, Ma L, Burns KH, Matzuk MM. Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice. Proc Natl Acad Sci U S A. 2004;101:7793-7798.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7793-7798
-
-
Yan, W.1
Ma, L.2
Burns, K.H.3
Matzuk, M.M.4
-
21
-
-
5444262510
-
Protective role of Nd1 in doxorubicin-induced cardiotoxicity
-
Fujimura L, Matsudo Y, Kang M, Takamori Y, Tokuhisa T, Hatano M. Protective role of Nd1 in doxorubicin-induced cardiotoxicity. Cardiovasc Res. 2004;64:315-321.
-
(2004)
Cardiovasc Res
, vol.64
, pp. 315-321
-
-
Fujimura, L.1
Matsudo, Y.2
Kang, M.3
Takamori, Y.4
Tokuhisa, T.5
Hatano, M.6
-
22
-
-
1542344034
-
Novel kelch-like protein, KLEIP, is involved in actin assembly at cell-cell contact sites of Madin-Darby canine kidney cells
-
Hara T, Ishida H, Raziuddin R, Dorkhom S, Kamijo K, Miki T. Novel kelch-like protein, KLEIP, is involved in actin assembly at cell-cell contact sites of Madin-Darby canine kidney cells. Mol Biol Cell. 2004;15:1172-1184.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1172-1184
-
-
Hara, T.1
Ishida, H.2
Raziuddin, R.3
Dorkhom, S.4
Kamijo, K.5
Miki, T.6
-
23
-
-
33644877968
-
A3 adenosine receptors modulate hypoxia-inducible factor-1α expression in human A375 melanoma cells
-
Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Leung E, MacLennan S, Baraldi PG, Borea PA. A3 adenosine receptors modulate hypoxia-inducible factor-1α expression in human A375 melanoma cells. Neoplasia. 2005;7:894-903.
-
(2005)
Neoplasia
, vol.7
, pp. 894-903
-
-
Merighi, S.1
Benini, A.2
Mirandola, P.3
Gessi, S.4
Varani, K.5
Leung, E.6
MacLennan, S.7
Baraldi, P.G.8
Borea, P.A.9
-
24
-
-
0037017811
-
Inhibitory effect on expression of angiogenic factors by antiangiogenic agents in renal cell carcinoma
-
Sasamura H, Takahashi A, Miyao N, Yanase M, Masumori N, Kitamura H, Itoh N, Tsukamoto T. Inhibitory effect on expression of angiogenic factors by antiangiogenic agents in renal cell carcinoma. Br J Cancer. 2002;86:768-773.
-
(2002)
Br J Cancer
, vol.86
, pp. 768-773
-
-
Sasamura, H.1
Takahashi, A.2
Miyao, N.3
Yanase, M.4
Masumori, N.5
Kitamura, H.6
Itoh, N.7
Tsukamoto, T.8
-
25
-
-
0016709007
-
Ultrastructural identification of umbilical cord vein endothelium in situ and in culture
-
Elgjo RF, Henriksen T, Evensen SA. Ultrastructural identification of umbilical cord vein endothelium in situ and in culture. Cell Tissue Res. 1975;162:49-59.
-
(1975)
Cell Tissue Res
, vol.162
, pp. 49-59
-
-
Elgjo, R.F.1
Henriksen, T.2
Evensen, S.A.3
-
26
-
-
0032583125
-
Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation
-
Korff T, Augustin HG. Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J Cell Biol. 1998;143:1341-1352.
-
(1998)
J Cell Biol
, vol.143
, pp. 1341-1352
-
-
Korff, T.1
Augustin, H.G.2
-
27
-
-
0026592533
-
Quantitative analysis of autocrineregulated, matrix-induced, and tumor cell-stimulated endothelial cell migration using a silicon template compartmentalization technique
-
Augustin-Voss HG, Pauli BU. Quantitative analysis of autocrineregulated, matrix-induced, and tumor cell-stimulated endothelial cell migration using a silicon template compartmentalization technique. Exp Cell Res. 1992;198:221-227.
-
(1992)
Exp Cell Res
, vol.198
, pp. 221-227
-
-
Augustin-Voss, H.G.1
Pauli, B.U.2
-
28
-
-
30444442692
-
Inhibition of hypoxia-inducible factor activity in endothelial cells disrupts embryonic cardiovascular development
-
Licht AH, Muller-Holtkamp F, Flamme I, Breier G. Inhibition of hypoxia-inducible factor activity in endothelial cells disrupts embryonic cardiovascular development. Blood. 2006;107:584-590.
-
(2006)
Blood
, vol.107
, pp. 584-590
-
-
Licht, A.H.1
Muller-Holtkamp, F.2
Flamme, I.3
Breier, G.4
-
29
-
-
7944224442
-
Loss of HIF-1alpha in endothelial cells disrupts a hypoxiadriven VEGF autocrine loop necessary for tumorigenesis
-
Tang N, Wang L, Esko J, Giordano FJ, Huang Y, Gerber HP, Ferrara N, Johnson RS. Loss of HIF-1alpha in endothelial cells disrupts a hypoxiadriven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell. 2004;6:485-495.
-
(2004)
Cancer Cell
, vol.6
, pp. 485-495
-
-
Tang, N.1
Wang, L.2
Esko, J.3
Giordano, F.J.4
Huang, Y.5
Gerber, H.P.6
Ferrara, N.7
Johnson, R.S.8
-
30
-
-
0037390915
-
The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression, and angiogenesis
-
Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH. The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression, and angiogenesis. FASEB J. 2003;17:761-763.
-
(2003)
FASEB J
, vol.17
, pp. 761-763
-
-
Linden, T.1
Katschinski, D.M.2
Eckhardt, K.3
Scheid, A.4
Pagel, H.5
Wenger, R.H.6
-
31
-
-
0036838846
-
Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo
-
Pham I, Uchida T, Planes C, Ware LB, Kaner R, Matthay MA, Clerici C. Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2002;283:L1133-L1142.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Pham, I.1
Uchida, T.2
Planes, C.3
Ware, L.B.4
Kaner, R.5
Matthay, M.A.6
Clerici, C.7
-
32
-
-
0036882302
-
CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2
-
Piret JP, Mottet D, Raes M, Michiels C. CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2. Ann N Y Acad Sci. 2002;973:443-447.
-
(2002)
Ann N Y Acad Sci
, vol.973
, pp. 443-447
-
-
Piret, J.P.1
Mottet, D.2
Raes, M.3
Michiels, C.4
-
33
-
-
0027502565
-
Oncogene ect2 is related to regulators of small GTP-binding proteins
-
Miki T, Smith CL, Long JE, Eva A, Fleming TP. Oncogene ect2 is related to regulators of small GTP-binding proteins. Nature. 1993;362:462-465.
-
(1993)
Nature
, vol.362
, pp. 462-465
-
-
Miki, T.1
Smith, C.L.2
Long, J.E.3
Eva, A.4
Fleming, T.P.5
-
34
-
-
3242702211
-
Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity
-
Liu XF, Ishida H, Raziuddin R, Miki T. Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity. Mol Cell Biol. 2004;24:6665-6675.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6665-6675
-
-
Liu, X.F.1
Ishida, H.2
Raziuddin, R.3
Miki, T.4
-
35
-
-
27744546286
-
Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner
-
Niiya F, Xie X, Lee KS, Inoue H, Miki T. Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner. J Biol Chem. 2005;280:36502-36509.
-
(2005)
J Biol Chem
, vol.280
, pp. 36502-36509
-
-
Niiya, F.1
Xie, X.2
Lee, K.S.3
Inoue, H.4
Miki, T.5
-
36
-
-
28544448876
-
The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells
-
2005;6:1163-1168
-
Morita K, Hirono K, Han M. The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells. EMBO Rep. 2005;6:1163-1168.
-
EMBO Rep
-
-
Morita, K.1
Hirono, K.2
Han, M.3
-
37
-
-
31544476883
-
Cytokinesis regulator ECT2 changes its conformation through phosphorylation at Thr-341 in G2/M phase
-
Hara T, Abe M, Inoue H, Yu LR, Veenstra TD, Kang YH, Lee KS, Miki T. Cytokinesis regulator ECT2 changes its conformation through phosphorylation at Thr-341 in G2/M phase. Oncogene. 2006;25:566-578.
-
(2006)
Oncogene
, vol.25
, pp. 566-578
-
-
Hara, T.1
Abe, M.2
Inoue, H.3
Yu, L.R.4
Veenstra, T.D.5
Kang, Y.H.6
Lee, K.S.7
Miki, T.8
-
38
-
-
27744494043
-
Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival
-
Allen E, Ding J, Wang W, Pramanik S, Chou J, Yau V, Yang Y. Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival. Nature. 2005;438:224-228.
-
(2005)
Nature
, vol.438
, pp. 224-228
-
-
Allen, E.1
Ding, J.2
Wang, W.3
Pramanik, S.4
Chou, J.5
Yau, V.6
Yang, Y.7
-
39
-
-
33645714061
-
The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
-
Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nat Cell Biol. 2006;8:348-357.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 348-357
-
-
Angers, S.1
Thorpe, C.J.2
Biechele, T.L.3
Goldenberg, S.J.4
Zheng, N.5
MacCoss, M.J.6
Moon, R.T.7
-
40
-
-
4544294365
-
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: Oxidative stress sensing by a Cul3-Keap1 ligase
-
Cullinan SB, Gordan JD, Jin J, Harper JW, Diehl JA. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell Biol. 2004;24:8477-8486.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8477-8486
-
-
Cullinan, S.B.1
Gordan, J.D.2
Jin, J.3
Harper, J.W.4
Diehl, J.A.5
-
41
-
-
0038348531
-
HIF-1alpha mRNA and protein up-regulation involves Rho GTPase expression during hypoxia in renal cell carcinoma
-
Turcotte S, Desrosiers RR, Beliveau R. HIF-1alpha mRNA and protein up-regulation involves Rho GTPase expression during hypoxia in renal cell carcinoma. J Cell Sci. 2003;116:2247-2260.
-
(2003)
J Cell Sci
, vol.116
, pp. 2247-2260
-
-
Turcotte, S.1
Desrosiers, R.R.2
Beliveau, R.3
|