메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages

Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: Impact on sorafenib cytotoxicity

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; GENISTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; CARRIER PROTEIN; MICRORNA; MIRN379 MICRORNA, HUMAN; NICOTINAMIDE; PHYTOESTROGEN; SORAFENIB;

EID: 84924940483     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119502     Document Type: Article
Times cited : (66)

References (56)
  • 1
    • 84903199903 scopus 로고    scopus 로고
    • DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma
    • PMID: 24976726
    • Anwar SL, Lehmann U. DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol. 2014; 20: 7894-7913. doi: 10.3748/wjg.v20.i24.7894 PMID: 24976726
    • (2014) World J Gastroenterol , vol.20 , pp. 7894-7913
    • Anwar, S.L.1    Lehmann, U.2
  • 2
    • 84910630922 scopus 로고    scopus 로고
    • Drug therapy for advanced-stage liver cancer
    • PMID: 24945003
    • Peck-Radosavljevic M. Drug therapy for advanced-stage liver cancer. Liver Cancer. 2014; 3: 125-131. doi: 10.1159/000343868 PMID: 24945003
    • (2014) Liver Cancer , vol.3 , pp. 125-131
    • Peck-Radosavljevic, M.1
  • 3
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • PMID: 22353262
    • Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012; 379: 1245-1255. doi: 10.1016/S0140-6736(11)61347-0 PMID: 22353262
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 4
    • 77954781214 scopus 로고    scopus 로고
    • Sorafenib: A clinical and pharmacologic review
    • PMID: 20586710
    • Iyer R, Fetterly G, Lugade A, Thanavala Y. Sorafenib: a clinical and pharmacologic review. Expert Opin Pharmacother. 2010; 11: 1943-1955. doi: 10.1517/14656566.2010.496453 PMID: 20586710
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1943-1955
    • Iyer, R.1    Fetterly, G.2    Lugade, A.3    Thanavala, Y.4
  • 6
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
    • PMID: 19095497
    • Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, Kim JS, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol. 2009; 10: 25-34. doi: 10.1016/S1470-2045(08)70285-7 PMID: 19095497
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3    Tsao, C.J.4    Qin, S.5    Kim, J.S.6
  • 7
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • PMID: 12535572
    • Schinkel AH, Jonker JW. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev. 2003; 55: 3-29. PMID: 12535572
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 8
    • 33644770013 scopus 로고    scopus 로고
    • MRP2 and 3 in health and disease
    • PMID: 16387425
    • Borst P, Zelcer N, van de Wetering K. MRP2 and 3 in health and disease. Cancer Lett. 2006; 234: 51-61. PMID: 16387425
    • (2006) Cancer Lett , vol.234 , pp. 51-61
    • Borst, P.1    Zelcer, N.2    Van De Wetering, K.3
  • 9
    • 33846706434 scopus 로고    scopus 로고
    • The apical conjugate efflux pump ABCC2 (MRP2)
    • PMID: 16847695
    • Nies AT, Keppler D. The apical conjugate efflux pump ABCC2 (MRP2) Pflugers Arch. 2007; 453: 643-659. PMID: 16847695
    • (2007) Pflugers Arch , vol.453 , pp. 643-659
    • Nies, A.T.1    Keppler, D.2
  • 10
    • 77949398878 scopus 로고    scopus 로고
    • Xenobiotic, bile acid, and cholesterol transporters: Function and regulation
    • PMID: 20103563
    • Klaassen CD, Aleksunes LM. Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacol Rev. 2010; 62: 1-96. doi: 10.1124/pr.109.002014 PMID: 20103563
    • (2010) Pharmacol Rev , vol.62 , pp. 1-96
    • Klaassen, C.D.1    Aleksunes, L.M.2
  • 11
    • 84893764885 scopus 로고    scopus 로고
    • Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P-glycoprotein expression
    • PMID: 24145579
    • Sun L, Chen W, Qu L, Wu J, Si J. Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P-glycoprotein expression. Mol Med Rep. 2013; 8: 1883-1887. doi: 10.3892/mmr.2013.1742 PMID: 24145579
    • (2013) Mol Med Rep , vol.8 , pp. 1883-1887
    • Sun, L.1    Chen, W.2    Qu, L.3    Wu, J.4    Si, J.5
  • 12
    • 84884263684 scopus 로고    scopus 로고
    • MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells
    • PMID: 23925649
    • Yang T, Zheng ZM, Li XN, Li ZF, Wang Y, Bai L, et al. MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells. Exp Biol Med (Maywood). 2013; 238: 1024-1032. doi: 10.1177/1535370213497321 PMID: 23925649
    • (2013) Exp Biol Med (Maywood) , vol.238 , pp. 1024-1032
    • Yang, T.1    Zheng, Z.M.2    Li, X.N.3    Li, Z.F.4    Wang, Y.5    Bai, L.6
  • 13
    • 77949478813 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma
    • PMID: 20204280
    • Korita PV, Wakai T, Shirai Y, Matsuda Y, Sakata J, Takamura M, et al. Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma. Oncol Rep. 2010; 23: 965-972. PMID: 20204280
    • (2010) Oncol Rep , vol.23 , pp. 965-972
    • Korita, P.V.1    Wakai, T.2    Shirai, Y.3    Matsuda, Y.4    Sakata, J.5    Takamura, M.6
  • 16
    • 78751631885 scopus 로고    scopus 로고
    • Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity
    • PMID: 20936466
    • Herzog M, Storch CH, Gut P, Kotlyar D, Füllekrug J, Ehehalt R, et al. Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity. Naunyn Schmiedebergs Arch Pharmacol. 2011; 383: 1-11. doi: 10.1007/s00210-010-0568-8 PMID: 20936466
    • (2011) Naunyn Schmiedebergs Arch Pharmacol , vol.383 , pp. 1-11
    • Herzog, M.1    Storch, C.H.2    Gut, P.3    Kotlyar, D.4    Füllekrug, J.5    Ehehalt, R.6
  • 17
    • 84872085481 scopus 로고    scopus 로고
    • Suppression of BCRP expression and restoration of sensitivity to chemotherapy in multidrug-resistant HCC cell line HEPG2/ADM by RNA interference
    • PMID: 23435138
    • Li H, Zhou S, Li T, Liu Z, Wu J, Zeng G, et al. Suppression of BCRP expression and restoration of sensitivity to chemotherapy in multidrug-resistant HCC cell line HEPG2/ADM by RNA interference. Hepatogastroenterology. 2012; 59: 2238-2242. doi: 10.5754/hge11781 PMID: 23435138
    • (2012) Hepatogastroenterology , vol.59 , pp. 2238-2242
    • Li, H.1    Zhou, S.2    Li, T.3    Liu, Z.4    Wu, J.5    Zeng, G.6
  • 18
  • 19
    • 79952333925 scopus 로고    scopus 로고
    • Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib
    • PMID: 21372398
    • Shibayama Y, Nakano K, Maeda H, Taguchi M, Ikeda R, Sugawara M, et al. Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib. Biol Pharm Bull. 2011; 34: 433-435. PMID: 21372398
    • (2011) Biol Pharm Bull , vol.34 , pp. 433-435
    • Shibayama, Y.1    Nakano, K.2    Maeda, H.3    Taguchi, M.4    Ikeda, R.5    Sugawara, M.6
  • 20
    • 84861227075 scopus 로고    scopus 로고
    • Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites
    • PMID: 22513143
    • Ghassabian S, Rawling T, Zhou F, Doddareddy MR, Tattam BN, Hibbs DE, et al. Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. Biochem Pharmacol. 2012; 84: 215-223. doi: 10.1016/j.bcp.2012.04.001 PMID: 22513143
    • (2012) Biochem Pharmacol , vol.84 , pp. 215-223
    • Ghassabian, S.1    Rawling, T.2    Zhou, F.3    Doddareddy, M.R.4    Tattam, B.N.5    Hibbs, D.E.6
  • 21
    • 84884557198 scopus 로고    scopus 로고
    • Anti-proliferative actions of N′-desmethylsorafenib in human breast cancer cells
    • PMID: 23732299
    • Cui PH, Rawling T, Gillani TB, Bourget K, Wang XS, Zhou F, et al. Anti-proliferative actions of N′-desmethylsorafenib in human breast cancer cells. Biochem Pharmacol. 2013; 86: 419-427. doi: 10.1016/j.bcp.2013.05.014 PMID: 23732299
    • (2013) Biochem Pharmacol , vol.86 , pp. 419-427
    • Cui, P.H.1    Rawling, T.2    Gillani, T.B.3    Bourget, K.4    Wang, X.S.5    Zhou, F.6
  • 22
    • 59149090185 scopus 로고    scopus 로고
    • Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor
    • PMID: 18606396
    • Köhle C, Bock KW. Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor. Biochem Pharmacol. 2009; 77: 689-699. doi: 10.1016/j.bcp.2008.05.020 PMID: 18606396
    • (2009) Biochem Pharmacol , vol.77 , pp. 689-699
    • Köhle, C.1    Bock, K.W.2
  • 23
    • 61449220882 scopus 로고    scopus 로고
    • Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways
    • PMID: 19034627
    • Li L, Stanton JD, Tolson AH, Luo Y, Wang H. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. Pharm Res. 2009; 26: 872-882. doi: 10.1007/s11095-008-9788-8 PMID: 19034627
    • (2009) Pharm Res , vol.26 , pp. 872-882
    • Li, L.1    Stanton, J.D.2    Tolson, A.H.3    Luo, Y.4    Wang, H.5
  • 24
    • 84924938616 scopus 로고    scopus 로고
    • Insulin growth factor 2 mRNA binding protein 1 (IGF2BP1) regulates translation of the multidrug resistance protein 2 (MRP2) by binding to its 5′-untranslated region (5′UTR)
    • Vore M, Zhao T, Zhang Y, Yan B, Thompson S. Insulin growth factor 2 mRNA binding protein 1 (IGF2BP1) regulates translation of the multidrug resistance protein 2 (MRP2) by binding to its 5′-untranslated region (5′UTR). FASEB J. 2011; 25: 1015.8.
    • (2011) FASEB J , vol.25 , pp. 1015.8
    • Vore, M.1    Zhao, T.2    Zhang, Y.3    Yan, B.4    Thompson, S.5
  • 25
    • 0035805536 scopus 로고    scopus 로고
    • Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
    • PMID: 11297522
    • Geick A, Eichelbaum M, Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem. 2001; 276: 14581-14587. PMID: 11297522
    • (2001) J Biol Chem , vol.276 , pp. 14581-14587
    • Geick, A.1    Eichelbaum, M.2    Burk, O.3
  • 26
    • 79960221018 scopus 로고    scopus 로고
    • Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379
    • PMID: 21540293
    • Haenisch S, Laechelt S, Bruckmueller H, Werk A, Noack A, Bruhn O, et al. Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. Mol Pharmacol. 2011; 80: 314-320. doi: 10.1124/mol.110.070714 PMID: 21540293
    • (2011) Mol Pharmacol , vol.80 , pp. 314-320
    • Haenisch, S.1    Laechelt, S.2    Bruckmueller, H.3    Werk, A.4    Noack, A.5    Bruhn, O.6
  • 27
    • 0036072803 scopus 로고    scopus 로고
    • Phyto-oestrogens and cancer
    • PMID: 12107024
    • Adlercreutz H. Phyto-oestrogens and cancer. Lancet Oncol. 2002; 3: 364-373. PMID: 12107024
    • (2002) Lancet Oncol , vol.3 , pp. 364-373
    • Adlercreutz, H.1
  • 28
    • 79451473244 scopus 로고    scopus 로고
    • Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat
    • PMID: 21147102
    • Floyd KA, Stella DR, Wang CC, Laurentz S, McCabe GP, Srivastava OP, et al. Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat. Exp Eye Res. 2011; 92: 120-127. doi: 10.1016/j.exer.2010.12.006 PMID: 21147102
    • (2011) Exp Eye Res , vol.92 , pp. 120-127
    • Floyd, K.A.1    Stella, D.R.2    Wang, C.C.3    Laurentz, S.4    McCabe, G.P.5    Srivastava, O.P.6
  • 29
    • 84857801780 scopus 로고    scopus 로고
    • Dietary, endocrine, and metabolic factors in the development of colorectal cancer
    • PMID: 22045273
    • Barone M, Lofano K, De Tullio N, Licinio R, Albano F, Di Leo A. Dietary, endocrine, and metabolic factors in the development of colorectal cancer. J Gastrointest Cancer. 2012; 43: 13-19. doi: 10.1007/s12029-011-9332-7 PMID: 22045273
    • (2012) J Gastrointest Cancer , vol.43 , pp. 13-19
    • Barone, M.1    Lofano, K.2    De Tullio, N.3    Licinio, R.4    Albano, F.5    Di Leo, A.6
  • 30
    • 0028815434 scopus 로고
    • Effect of genistein on in vitro and in vivo models of cancer
    • PMID: 7884564
    • Barnes S. Effect of genistein on in vitro and in vivo models of cancer. J Nutr. 1995; 125: 777S-783S. PMID: 7884564
    • (1995) J Nutr , vol.125 , pp. 777S-783S
    • Barnes, S.1
  • 31
    • 84875909806 scopus 로고    scopus 로고
    • Isoflavone genistein induces fluid secretion and morphological changes in the uteri of post-pubertal rats
    • PMID: 23569430
    • Salleh N, Helmy MM, Fadila KN, Yeong SO. Isoflavone genistein induces fluid secretion and morphological changes in the uteri of post-pubertal rats. Int J Med Sci. 2013; 10: 665-675. doi: 10.7150/ijms.5207 PMID: 23569430
    • (2013) Int J Med Sci , vol.10 , pp. 665-675
    • Salleh, N.1    Helmy, M.M.2    Fadila, K.N.3    Yeong, S.O.4
  • 32
    • 58549097262 scopus 로고    scopus 로고
    • Isoflavones in urine, saliva and blood of infants - data from a pilot study on the estrogenic activity of soy formula
    • PMID: 18665197
    • Cao Y, Calafat A, Doerge D, Umbach D, Bernbaum J, Twaddle NC, et al. Isoflavones in urine, saliva and blood of infants - data from a pilot study on the estrogenic activity of soy formula. J Expo Sci Environ Epidemiol. 2009; 19: 223-234. doi: 10.1038/jes.2008.44 PMID: 18665197
    • (2009) J Expo Sci Environ Epidemiol , vol.19 , pp. 223-234
    • Cao, Y.1    Calafat, A.2    Doerge, D.3    Umbach, D.4    Bernbaum, J.5    Twaddle, N.C.6
  • 33
    • 84879609929 scopus 로고    scopus 로고
    • Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis
    • Hishida M, Nomoto S, Inokawa Y, Hayashi M, Kanda M, Okamura Y, et al. Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis. Int J Oncol. 2014; 43: 88-94.
    • (2014) Int J Oncol , vol.43 , pp. 88-94
    • Hishida, M.1    Nomoto, S.2    Inokawa, Y.3    Hayashi, M.4    Kanda, M.5    Okamura, Y.6
  • 34
    • 84880360744 scopus 로고    scopus 로고
    • Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins
    • PMID: 23733894
    • Tu CC, Kumar VB, Day CH, Kuo WW, Yeh SP, Chen RJ, et al. Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins. J Mol Endocrinol. 2013; 51: 203-212. doi: 10.1530/JME-13-0085 PMID: 23733894
    • (2013) J Mol Endocrinol , vol.51 , pp. 203-212
    • Tu, C.C.1    Kumar, V.B.2    Day, C.H.3    Kuo, W.W.4    Yeh, S.P.5    Chen, R.J.6
  • 35
    • 84884564331 scopus 로고    scopus 로고
    • Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17 α-ethynylestradiol. Role of activator protein-1
    • PMID: 23747343
    • Ruiz ML, Rigalli JP, Arias A, Villanueva SS, Banchio C, Vore M, et al. Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17 α-ethynylestradiol. Role of activator protein-1. Biochem Pharmacol. 2013; 86: 401-409. doi: 10.1016/j.bcp.2013.05.025 PMID: 23747343
    • (2013) Biochem Pharmacol , vol.86 , pp. 401-409
    • Ruiz, M.L.1    Rigalli, J.P.2    Arias, A.3    Villanueva, S.S.4    Banchio, C.5    Vore, M.6
  • 36
    • 0027217613 scopus 로고
    • Bile canaliculus formation in cultured HepG2 cells
    • PMID: 8390592
    • Sormunen R, Eskelinen S, Lehto VP. Bile canaliculus formation in cultured HepG2 cells. Lab Invest. 1993; 68: 652-662. PMID: 8390592
    • (1993) Lab Invest , vol.68 , pp. 652-662
    • Sormunen, R.1    Eskelinen, S.2    Lehto, V.P.3
  • 37
    • 79956192123 scopus 로고    scopus 로고
    • Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells
    • PMID: 21459122
    • Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA. Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells. Toxicology. 2011; 285: 18-24. doi: 10.1016/j.tox.2011.03.015 PMID: 21459122
    • (2011) Toxicology , vol.285 , pp. 18-24
    • Rigalli, J.P.1    Ruiz, M.L.2    Perdomo, V.G.3    Villanueva, S.S.4    Mottino, A.D.5    Catania, V.A.6
  • 38
    • 84859992171 scopus 로고    scopus 로고
    • Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels
    • PMID: 22530027
    • Martins R, Proenc¸a D, Silva B, Barbosa C, Silva AL, Faustino P, et al. Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels. PLoS One. 2012; 7: e35461. doi: 10.1371/journal.pone.0035461 PMID: 22530027
    • (2012) PLoS One , vol.7 , pp. e35461
    • Martins, R.1    Proenc¸a, D.2    Silva, B.3    Barbosa, C.4    Silva, A.L.5    Faustino, P.6
  • 39
    • 30144441515 scopus 로고    scopus 로고
    • Biliary transport systems: Short-term regulation
    • PMID: 16399369
    • Kubitz R, Helmer A, Häussinger D. Biliary transport systems: short-term regulation. Methods Enzymol. 2005; 400: 542-557. PMID: 16399369
    • (2005) Methods Enzymol , vol.400 , pp. 542-557
    • Kubitz, R.1    Helmer, A.2    Häussinger, D.3
  • 40
    • 84872038118 scopus 로고    scopus 로고
    • Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: Involvement of pregnane-x-receptor
    • PMID: 23272261
    • Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, et al. Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane-x-receptor. PLoS Negl Trop Dis. 2012; 6: e1951. doi: 10.1371/journal.pntd.0001951 PMID: 23272261
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. e1951
    • Rigalli, J.P.1    Perdomo, V.G.2    Luquita, M.G.3    Villanueva, S.S.4    Arias, A.5    Theile, D.6
  • 42
    • 84871604522 scopus 로고    scopus 로고
    • The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells
    • PMID: 23200901
    • Ye L, Yang X, Yang Z, Gao S, Yin T, Liu W, et al. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells. Toxicol. Lett. 2013; 216: 86-99. doi: 10.1016/j.toxlet.2012.11.011 PMID: 23200901
    • (2013) Toxicol. Lett. , vol.216 , pp. 86-99
    • Ye, L.1    Yang, X.2    Yang, Z.3    Gao, S.4    Yin, T.5    Liu, W.6
  • 43
    • 84862092135 scopus 로고    scopus 로고
    • Drug interaction of efavirenz and midazolam: Efavirenz activates the CYP3A-mediated midazolam 1′-hydroxylation in vitro
    • PMID: 22019630
    • Keubler A, Weiss J, Haefeli WE, Mikus G, Burhenne J. Drug interaction of efavirenz and midazolam: efavirenz activates the CYP3A-mediated midazolam 1′-hydroxylation in vitro. Drug Metab Dispos. 2012; 40: 178-182. doi: 10.1124/dmd.111.042879 PMID: 22019630
    • (2012) Drug Metab Dispos , vol.40 , pp. 178-182
    • Keubler, A.1    Weiss, J.2    Haefeli, W.E.3    Mikus, G.4    Burhenne, J.5
  • 44
    • 79251581020 scopus 로고    scopus 로고
    • The art of microRNA research
    • PMID: 21252150
    • Van Rooij E. The art of microRNA research. Circ Res. 2011; 108: 219-234. doi: 10.1161/CIRCRESAHA.110.227496 PMID: 21252150
    • (2011) Circ Res , vol.108 , pp. 219-234
    • Van Rooij, E.1
  • 45
    • 64049102360 scopus 로고    scopus 로고
    • Dynamic localization of hepatocellular transporters in health and disease
    • PMID: 19058304
    • Roma MG, Crocenzi FA, Mottino AD. Dynamic localization of hepatocellular transporters in health and disease. World J Gastroenterol. 2008; 14: 6786-6801. PMID: 19058304
    • (2008) World J Gastroenterol , vol.14 , pp. 6786-6801
    • Roma, M.G.1    Crocenzi, F.A.2    Mottino, A.D.3
  • 46
    • 84881353168 scopus 로고    scopus 로고
    • Genistein down-regulates miR-223 expression in pancreatic cancer cells
    • PMID: 23834147
    • Ma J, Cheng L, Liu H, Zhang J, Shi Y, Zeng F, et al. Genistein down-regulates miR-223 expression in pancreatic cancer cells. Curr Drug Targets. 2013; 14: 1150-1156. PMID: 23834147
    • (2013) Curr Drug Targets , vol.14 , pp. 1150-1156
    • Ma, J.1    Cheng, L.2    Liu, H.3    Zhang, J.4    Shi, Y.5    Zeng, F.6
  • 47
    • 65349184457 scopus 로고    scopus 로고
    • Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner
    • PMID: 19297428
    • Li Y, Ross-Viola JS, Shay NF, Moore DD, Ricketts ML. Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner. J Nutr. 2009; 139: 898-904. doi: 10.3945/jn.108.103572 PMID: 19297428
    • (2009) J Nutr , vol.139 , pp. 898-904
    • Li, Y.1    Ross-Viola, J.S.2    Shay, N.F.3    Moore, D.D.4    Ricketts, M.L.5
  • 48
    • 84873033456 scopus 로고    scopus 로고
    • Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury
    • PMID: 22716961
    • Zhang T, Wang F, Xu HX, Yi L, Qin Y, Chang H, et al. Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury. Br J Nutr. 2013; 109: 223-235. doi: 10.1017/S0007114512001110 PMID: 22716961
    • (2013) Br J Nutr , vol.109 , pp. 223-235
    • Zhang, T.1    Wang, F.2    Xu, H.X.3    Yi, L.4    Qin, Y.5    Chang, H.6
  • 49
    • 84902967582 scopus 로고    scopus 로고
    • Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity
    • PMID: 24685904
    • Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, et al. Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity. Toxicology. 2014; 320: 46-55. doi: 10.1016/j.tox.2014.03.007 PMID: 24685904
    • (2014) Toxicology , vol.320 , pp. 46-55
    • Arias, A.1    Rigalli, J.P.2    Villanueva, S.S.3    Ruiz, M.L.4    Luquita, M.G.5    Perdomo, V.G.6
  • 50
    • 34548079796 scopus 로고    scopus 로고
    • High-dose acetaminophen inhibits the lethal effect of doxorubicin in HepG2 cells: The role of P-glycoprotein and mitogen-activated protein kinase p44/p42 pathway
    • Manov I, Bashenko Y, Eliaz-Wolkowicz A, Mizrahi M, Liran O, Iancu TC. High-dose acetaminophen inhibits the lethal effect of doxorubicin in HepG2 cells: the role of P-glycoprotein and mitogen-activated protein kinase p44/p42 pathway. J Pharmacol Exp Ther. 2007; 332: 1013-1022.
    • (2007) J Pharmacol Exp Ther , vol.332 , pp. 1013-1022
    • Manov, I.1    Bashenko, Y.2    Eliaz-Wolkowicz, A.3    Mizrahi, M.4    Liran, O.5    Iancu, T.C.6
  • 51
    • 84880805730 scopus 로고    scopus 로고
    • Steroidal saponin of Trillium tschonoskii. Reverses multidrug resistance of hepatocellular carcinoma
    • PMID: 23786867
    • Wang H, Zhai Z, Li N, Jin H, Chen J, Yuan S, et al. Steroidal saponin of Trillium tschonoskii. Reverses multidrug resistance of hepatocellular carcinoma. Phytomedicine. 2013; 20: 985-991. doi: 10.1016/j.phymed.2013.04.014 PMID: 23786867
    • (2013) Phytomedicine , vol.20 , pp. 985-991
    • Wang, H.1    Zhai, Z.2    Li, N.3    Jin, H.4    Chen, J.5    Yuan, S.6
  • 52
    • 35048895704 scopus 로고    scopus 로고
    • Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs
    • PMID: 17704753
    • Folmer Y, Schneider M, Blum HE, Hafkemeyer P. Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs. Cancer Gene Ther. 2007; 14: 875-884. PMID: 17704753
    • (2007) Cancer Gene Ther , vol.14 , pp. 875-884
    • Folmer, Y.1    Schneider, M.2    Blum, H.E.3    Hafkemeyer, P.4
  • 53
    • 33749441773 scopus 로고    scopus 로고
    • Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4
    • PMID: 11741214
    • Achira M, Suzuki H, Ito K, Sugiyama Y. Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4. AAPS PharmSci. 1999; 1: E18. PMID: 11741214
    • (1999) AAPS PharmSci , vol.1 , pp. E18
    • Achira, M.1    Suzuki, H.2    Ito, K.3    Sugiyama, Y.4
  • 54
    • 0019966544 scopus 로고
    • Growth of human hepatoma cell lines with differentiated functions in chemically defined medium
    • PMID: 6286115
    • Nakabayashi H, Taketa K, Miyano K, Yamane T, Sato J. Growth of human hepatoma cell lines with differentiated functions in chemically defined medium. Cancer Res. 1982; 42: 3858-3863. PMID: 6286115
    • (1982) Cancer Res , vol.42 , pp. 3858-3863
    • Nakabayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 55
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • PMID: 18645025
    • Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF, et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther. 2008; 7: 2152-2159. doi: 10.1158/1535-7163.MCT-08-0021 PMID: 18645025
    • (2008) Mol Cancer Ther , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3    Ilnytskyy, Y.4    Tryndyak, V.P.5    Chekhun, V.F.6
  • 56
    • 84869866890 scopus 로고    scopus 로고
    • MicroRNA and cancer
    • PMID: 23102669
    • Jansson MD, Lund AH. MicroRNA and cancer. Mol Oncol. 2012; 6: 590-610. doi: 10.1016/j.molonc.2012.09.006 PMID: 23102669
    • (2012) Mol Oncol , vol.6 , pp. 590-610
    • Jansson, M.D.1    Lund, A.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.