-
1
-
-
84903199903
-
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma
-
PMID: 24976726
-
Anwar SL, Lehmann U. DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol. 2014; 20: 7894-7913. doi: 10.3748/wjg.v20.i24.7894 PMID: 24976726
-
(2014)
World J Gastroenterol
, vol.20
, pp. 7894-7913
-
-
Anwar, S.L.1
Lehmann, U.2
-
2
-
-
84910630922
-
Drug therapy for advanced-stage liver cancer
-
PMID: 24945003
-
Peck-Radosavljevic M. Drug therapy for advanced-stage liver cancer. Liver Cancer. 2014; 3: 125-131. doi: 10.1159/000343868 PMID: 24945003
-
(2014)
Liver Cancer
, vol.3
, pp. 125-131
-
-
Peck-Radosavljevic, M.1
-
3
-
-
84859212951
-
Hepatocellular carcinoma
-
PMID: 22353262
-
Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012; 379: 1245-1255. doi: 10.1016/S0140-6736(11)61347-0 PMID: 22353262
-
(2012)
Lancet
, vol.379
, pp. 1245-1255
-
-
Forner, A.1
Llovet, J.M.2
Bruix, J.3
-
4
-
-
77954781214
-
Sorafenib: A clinical and pharmacologic review
-
PMID: 20586710
-
Iyer R, Fetterly G, Lugade A, Thanavala Y. Sorafenib: a clinical and pharmacologic review. Expert Opin Pharmacother. 2010; 11: 1943-1955. doi: 10.1517/14656566.2010.496453 PMID: 20586710
-
(2010)
Expert Opin Pharmacother
, vol.11
, pp. 1943-1955
-
-
Iyer, R.1
Fetterly, G.2
Lugade, A.3
Thanavala, Y.4
-
5
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
PMID: 18650514
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 2008; 359: 378-390. doi: 10.1056/NEJMoa0708857 PMID: 18650514
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
-
6
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
PMID: 19095497
-
Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, Kim JS, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol. 2009; 10: 25-34. doi: 10.1016/S1470-2045(08)70285-7 PMID: 19095497
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
Kim, J.S.6
-
7
-
-
0037457802
-
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
-
PMID: 12535572
-
Schinkel AH, Jonker JW. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev. 2003; 55: 3-29. PMID: 12535572
-
(2003)
Adv Drug Deliv Rev
, vol.55
, pp. 3-29
-
-
Schinkel, A.H.1
Jonker, J.W.2
-
8
-
-
33644770013
-
MRP2 and 3 in health and disease
-
PMID: 16387425
-
Borst P, Zelcer N, van de Wetering K. MRP2 and 3 in health and disease. Cancer Lett. 2006; 234: 51-61. PMID: 16387425
-
(2006)
Cancer Lett
, vol.234
, pp. 51-61
-
-
Borst, P.1
Zelcer, N.2
Van De Wetering, K.3
-
9
-
-
33846706434
-
The apical conjugate efflux pump ABCC2 (MRP2)
-
PMID: 16847695
-
Nies AT, Keppler D. The apical conjugate efflux pump ABCC2 (MRP2) Pflugers Arch. 2007; 453: 643-659. PMID: 16847695
-
(2007)
Pflugers Arch
, vol.453
, pp. 643-659
-
-
Nies, A.T.1
Keppler, D.2
-
10
-
-
77949398878
-
Xenobiotic, bile acid, and cholesterol transporters: Function and regulation
-
PMID: 20103563
-
Klaassen CD, Aleksunes LM. Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacol Rev. 2010; 62: 1-96. doi: 10.1124/pr.109.002014 PMID: 20103563
-
(2010)
Pharmacol Rev
, vol.62
, pp. 1-96
-
-
Klaassen, C.D.1
Aleksunes, L.M.2
-
11
-
-
84893764885
-
Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P-glycoprotein expression
-
PMID: 24145579
-
Sun L, Chen W, Qu L, Wu J, Si J. Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P-glycoprotein expression. Mol Med Rep. 2013; 8: 1883-1887. doi: 10.3892/mmr.2013.1742 PMID: 24145579
-
(2013)
Mol Med Rep
, vol.8
, pp. 1883-1887
-
-
Sun, L.1
Chen, W.2
Qu, L.3
Wu, J.4
Si, J.5
-
12
-
-
84884263684
-
MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells
-
PMID: 23925649
-
Yang T, Zheng ZM, Li XN, Li ZF, Wang Y, Bai L, et al. MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells. Exp Biol Med (Maywood). 2013; 238: 1024-1032. doi: 10.1177/1535370213497321 PMID: 23925649
-
(2013)
Exp Biol Med (Maywood)
, vol.238
, pp. 1024-1032
-
-
Yang, T.1
Zheng, Z.M.2
Li, X.N.3
Li, Z.F.4
Wang, Y.5
Bai, L.6
-
13
-
-
77949478813
-
Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma
-
PMID: 20204280
-
Korita PV, Wakai T, Shirai Y, Matsuda Y, Sakata J, Takamura M, et al. Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma. Oncol Rep. 2010; 23: 965-972. PMID: 20204280
-
(2010)
Oncol Rep
, vol.23
, pp. 965-972
-
-
Korita, P.V.1
Wakai, T.2
Shirai, Y.3
Matsuda, Y.4
Sakata, J.5
Takamura, M.6
-
14
-
-
13044294031
-
MRP3, an organic anion transporter able to transport anti-cancer drugs
-
PMID: 10359813
-
Kool M, van der Linden M, de Haas M, Scheffer GL, de Vree JM, Smith AJ, et al. MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc Natl Acad Sci U S A. 1999; 96: 6914-6919. PMID: 10359813
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6914-6919
-
-
Kool, M.1
Van Der Linden, M.2
De Haas, M.3
Scheffer, G.L.4
De Vree, J.M.5
Smith, A.J.6
-
15
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
PMID: 9861027
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A. 1998; 95: 15665-15670. PMID: 9861027
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
-
16
-
-
78751631885
-
Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity
-
PMID: 20936466
-
Herzog M, Storch CH, Gut P, Kotlyar D, Füllekrug J, Ehehalt R, et al. Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity. Naunyn Schmiedebergs Arch Pharmacol. 2011; 383: 1-11. doi: 10.1007/s00210-010-0568-8 PMID: 20936466
-
(2011)
Naunyn Schmiedebergs Arch Pharmacol
, vol.383
, pp. 1-11
-
-
Herzog, M.1
Storch, C.H.2
Gut, P.3
Kotlyar, D.4
Füllekrug, J.5
Ehehalt, R.6
-
17
-
-
84872085481
-
Suppression of BCRP expression and restoration of sensitivity to chemotherapy in multidrug-resistant HCC cell line HEPG2/ADM by RNA interference
-
PMID: 23435138
-
Li H, Zhou S, Li T, Liu Z, Wu J, Zeng G, et al. Suppression of BCRP expression and restoration of sensitivity to chemotherapy in multidrug-resistant HCC cell line HEPG2/ADM by RNA interference. Hepatogastroenterology. 2012; 59: 2238-2242. doi: 10.5754/hge11781 PMID: 23435138
-
(2012)
Hepatogastroenterology
, vol.59
, pp. 2238-2242
-
-
Li, H.1
Zhou, S.2
Li, T.3
Liu, Z.4
Wu, J.5
Zeng, G.6
-
18
-
-
76649109232
-
Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation
-
PMID: 20103600
-
Lagas JS, van Waterschoot RA, Sparidans RW, Wagenaar E, Beijnen JH, Schinkel AH. Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation. Mol Cancer Ther. 2010; 9: 319-326. doi: 10.1158/1535-7163.MCT-09-0663 PMID: 20103600
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 319-326
-
-
Lagas, J.S.1
Van Waterschoot, R.A.2
Sparidans, R.W.3
Wagenaar, E.4
Beijnen, J.H.5
Schinkel, A.H.6
-
19
-
-
79952333925
-
Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib
-
PMID: 21372398
-
Shibayama Y, Nakano K, Maeda H, Taguchi M, Ikeda R, Sugawara M, et al. Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib. Biol Pharm Bull. 2011; 34: 433-435. PMID: 21372398
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 433-435
-
-
Shibayama, Y.1
Nakano, K.2
Maeda, H.3
Taguchi, M.4
Ikeda, R.5
Sugawara, M.6
-
20
-
-
84861227075
-
Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites
-
PMID: 22513143
-
Ghassabian S, Rawling T, Zhou F, Doddareddy MR, Tattam BN, Hibbs DE, et al. Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. Biochem Pharmacol. 2012; 84: 215-223. doi: 10.1016/j.bcp.2012.04.001 PMID: 22513143
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 215-223
-
-
Ghassabian, S.1
Rawling, T.2
Zhou, F.3
Doddareddy, M.R.4
Tattam, B.N.5
Hibbs, D.E.6
-
21
-
-
84884557198
-
Anti-proliferative actions of N′-desmethylsorafenib in human breast cancer cells
-
PMID: 23732299
-
Cui PH, Rawling T, Gillani TB, Bourget K, Wang XS, Zhou F, et al. Anti-proliferative actions of N′-desmethylsorafenib in human breast cancer cells. Biochem Pharmacol. 2013; 86: 419-427. doi: 10.1016/j.bcp.2013.05.014 PMID: 23732299
-
(2013)
Biochem Pharmacol
, vol.86
, pp. 419-427
-
-
Cui, P.H.1
Rawling, T.2
Gillani, T.B.3
Bourget, K.4
Wang, X.S.5
Zhou, F.6
-
22
-
-
59149090185
-
Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor
-
PMID: 18606396
-
Köhle C, Bock KW. Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor. Biochem Pharmacol. 2009; 77: 689-699. doi: 10.1016/j.bcp.2008.05.020 PMID: 18606396
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 689-699
-
-
Köhle, C.1
Bock, K.W.2
-
23
-
-
61449220882
-
Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways
-
PMID: 19034627
-
Li L, Stanton JD, Tolson AH, Luo Y, Wang H. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. Pharm Res. 2009; 26: 872-882. doi: 10.1007/s11095-008-9788-8 PMID: 19034627
-
(2009)
Pharm Res
, vol.26
, pp. 872-882
-
-
Li, L.1
Stanton, J.D.2
Tolson, A.H.3
Luo, Y.4
Wang, H.5
-
24
-
-
84924938616
-
Insulin growth factor 2 mRNA binding protein 1 (IGF2BP1) regulates translation of the multidrug resistance protein 2 (MRP2) by binding to its 5′-untranslated region (5′UTR)
-
Vore M, Zhao T, Zhang Y, Yan B, Thompson S. Insulin growth factor 2 mRNA binding protein 1 (IGF2BP1) regulates translation of the multidrug resistance protein 2 (MRP2) by binding to its 5′-untranslated region (5′UTR). FASEB J. 2011; 25: 1015.8.
-
(2011)
FASEB J
, vol.25
, pp. 1015.8
-
-
Vore, M.1
Zhao, T.2
Zhang, Y.3
Yan, B.4
Thompson, S.5
-
25
-
-
0035805536
-
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
-
PMID: 11297522
-
Geick A, Eichelbaum M, Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem. 2001; 276: 14581-14587. PMID: 11297522
-
(2001)
J Biol Chem
, vol.276
, pp. 14581-14587
-
-
Geick, A.1
Eichelbaum, M.2
Burk, O.3
-
26
-
-
79960221018
-
Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379
-
PMID: 21540293
-
Haenisch S, Laechelt S, Bruckmueller H, Werk A, Noack A, Bruhn O, et al. Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. Mol Pharmacol. 2011; 80: 314-320. doi: 10.1124/mol.110.070714 PMID: 21540293
-
(2011)
Mol Pharmacol
, vol.80
, pp. 314-320
-
-
Haenisch, S.1
Laechelt, S.2
Bruckmueller, H.3
Werk, A.4
Noack, A.5
Bruhn, O.6
-
27
-
-
0036072803
-
Phyto-oestrogens and cancer
-
PMID: 12107024
-
Adlercreutz H. Phyto-oestrogens and cancer. Lancet Oncol. 2002; 3: 364-373. PMID: 12107024
-
(2002)
Lancet Oncol
, vol.3
, pp. 364-373
-
-
Adlercreutz, H.1
-
28
-
-
79451473244
-
Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat
-
PMID: 21147102
-
Floyd KA, Stella DR, Wang CC, Laurentz S, McCabe GP, Srivastava OP, et al. Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat. Exp Eye Res. 2011; 92: 120-127. doi: 10.1016/j.exer.2010.12.006 PMID: 21147102
-
(2011)
Exp Eye Res
, vol.92
, pp. 120-127
-
-
Floyd, K.A.1
Stella, D.R.2
Wang, C.C.3
Laurentz, S.4
McCabe, G.P.5
Srivastava, O.P.6
-
29
-
-
84857801780
-
Dietary, endocrine, and metabolic factors in the development of colorectal cancer
-
PMID: 22045273
-
Barone M, Lofano K, De Tullio N, Licinio R, Albano F, Di Leo A. Dietary, endocrine, and metabolic factors in the development of colorectal cancer. J Gastrointest Cancer. 2012; 43: 13-19. doi: 10.1007/s12029-011-9332-7 PMID: 22045273
-
(2012)
J Gastrointest Cancer
, vol.43
, pp. 13-19
-
-
Barone, M.1
Lofano, K.2
De Tullio, N.3
Licinio, R.4
Albano, F.5
Di Leo, A.6
-
30
-
-
0028815434
-
Effect of genistein on in vitro and in vivo models of cancer
-
PMID: 7884564
-
Barnes S. Effect of genistein on in vitro and in vivo models of cancer. J Nutr. 1995; 125: 777S-783S. PMID: 7884564
-
(1995)
J Nutr
, vol.125
, pp. 777S-783S
-
-
Barnes, S.1
-
31
-
-
84875909806
-
Isoflavone genistein induces fluid secretion and morphological changes in the uteri of post-pubertal rats
-
PMID: 23569430
-
Salleh N, Helmy MM, Fadila KN, Yeong SO. Isoflavone genistein induces fluid secretion and morphological changes in the uteri of post-pubertal rats. Int J Med Sci. 2013; 10: 665-675. doi: 10.7150/ijms.5207 PMID: 23569430
-
(2013)
Int J Med Sci
, vol.10
, pp. 665-675
-
-
Salleh, N.1
Helmy, M.M.2
Fadila, K.N.3
Yeong, S.O.4
-
32
-
-
58549097262
-
Isoflavones in urine, saliva and blood of infants - data from a pilot study on the estrogenic activity of soy formula
-
PMID: 18665197
-
Cao Y, Calafat A, Doerge D, Umbach D, Bernbaum J, Twaddle NC, et al. Isoflavones in urine, saliva and blood of infants - data from a pilot study on the estrogenic activity of soy formula. J Expo Sci Environ Epidemiol. 2009; 19: 223-234. doi: 10.1038/jes.2008.44 PMID: 18665197
-
(2009)
J Expo Sci Environ Epidemiol
, vol.19
, pp. 223-234
-
-
Cao, Y.1
Calafat, A.2
Doerge, D.3
Umbach, D.4
Bernbaum, J.5
Twaddle, N.C.6
-
33
-
-
84879609929
-
Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis
-
Hishida M, Nomoto S, Inokawa Y, Hayashi M, Kanda M, Okamura Y, et al. Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis. Int J Oncol. 2014; 43: 88-94.
-
(2014)
Int J Oncol
, vol.43
, pp. 88-94
-
-
Hishida, M.1
Nomoto, S.2
Inokawa, Y.3
Hayashi, M.4
Kanda, M.5
Okamura, Y.6
-
34
-
-
84880360744
-
Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins
-
PMID: 23733894
-
Tu CC, Kumar VB, Day CH, Kuo WW, Yeh SP, Chen RJ, et al. Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins. J Mol Endocrinol. 2013; 51: 203-212. doi: 10.1530/JME-13-0085 PMID: 23733894
-
(2013)
J Mol Endocrinol
, vol.51
, pp. 203-212
-
-
Tu, C.C.1
Kumar, V.B.2
Day, C.H.3
Kuo, W.W.4
Yeh, S.P.5
Chen, R.J.6
-
35
-
-
84884564331
-
Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17 α-ethynylestradiol. Role of activator protein-1
-
PMID: 23747343
-
Ruiz ML, Rigalli JP, Arias A, Villanueva SS, Banchio C, Vore M, et al. Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17 α-ethynylestradiol. Role of activator protein-1. Biochem Pharmacol. 2013; 86: 401-409. doi: 10.1016/j.bcp.2013.05.025 PMID: 23747343
-
(2013)
Biochem Pharmacol
, vol.86
, pp. 401-409
-
-
Ruiz, M.L.1
Rigalli, J.P.2
Arias, A.3
Villanueva, S.S.4
Banchio, C.5
Vore, M.6
-
36
-
-
0027217613
-
Bile canaliculus formation in cultured HepG2 cells
-
PMID: 8390592
-
Sormunen R, Eskelinen S, Lehto VP. Bile canaliculus formation in cultured HepG2 cells. Lab Invest. 1993; 68: 652-662. PMID: 8390592
-
(1993)
Lab Invest
, vol.68
, pp. 652-662
-
-
Sormunen, R.1
Eskelinen, S.2
Lehto, V.P.3
-
37
-
-
79956192123
-
Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells
-
PMID: 21459122
-
Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA. Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells. Toxicology. 2011; 285: 18-24. doi: 10.1016/j.tox.2011.03.015 PMID: 21459122
-
(2011)
Toxicology
, vol.285
, pp. 18-24
-
-
Rigalli, J.P.1
Ruiz, M.L.2
Perdomo, V.G.3
Villanueva, S.S.4
Mottino, A.D.5
Catania, V.A.6
-
38
-
-
84859992171
-
Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels
-
PMID: 22530027
-
Martins R, Proenc¸a D, Silva B, Barbosa C, Silva AL, Faustino P, et al. Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels. PLoS One. 2012; 7: e35461. doi: 10.1371/journal.pone.0035461 PMID: 22530027
-
(2012)
PLoS One
, vol.7
, pp. e35461
-
-
Martins, R.1
Proenc¸a, D.2
Silva, B.3
Barbosa, C.4
Silva, A.L.5
Faustino, P.6
-
39
-
-
30144441515
-
Biliary transport systems: Short-term regulation
-
PMID: 16399369
-
Kubitz R, Helmer A, Häussinger D. Biliary transport systems: short-term regulation. Methods Enzymol. 2005; 400: 542-557. PMID: 16399369
-
(2005)
Methods Enzymol
, vol.400
, pp. 542-557
-
-
Kubitz, R.1
Helmer, A.2
Häussinger, D.3
-
40
-
-
84872038118
-
Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: Involvement of pregnane-x-receptor
-
PMID: 23272261
-
Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, et al. Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane-x-receptor. PLoS Negl Trop Dis. 2012; 6: e1951. doi: 10.1371/journal.pntd.0001951 PMID: 23272261
-
(2012)
PLoS Negl Trop Dis
, vol.6
, pp. e1951
-
-
Rigalli, J.P.1
Perdomo, V.G.2
Luquita, M.G.3
Villanueva, S.S.4
Arias, A.5
Theile, D.6
-
41
-
-
0037379938
-
Inhibition of P-glycoprotein by newer antidepressants
-
PMID: 12649369
-
Weiss J, Dormann SM, Martin-Facklam M, Kerpen CJ, Ketabi-Kiyanvash N, Haefeli WE. Inhibition of P-glycoprotein by newer antidepressants. J Pharmacol Exp Ther. 2003; 305: 197-204. PMID: 12649369
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 197-204
-
-
Weiss, J.1
Dormann, S.M.2
Martin-Facklam, M.3
Kerpen, C.J.4
Ketabi-Kiyanvash, N.5
Haefeli, W.E.6
-
42
-
-
84871604522
-
The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells
-
PMID: 23200901
-
Ye L, Yang X, Yang Z, Gao S, Yin T, Liu W, et al. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells. Toxicol. Lett. 2013; 216: 86-99. doi: 10.1016/j.toxlet.2012.11.011 PMID: 23200901
-
(2013)
Toxicol. Lett.
, vol.216
, pp. 86-99
-
-
Ye, L.1
Yang, X.2
Yang, Z.3
Gao, S.4
Yin, T.5
Liu, W.6
-
43
-
-
84862092135
-
Drug interaction of efavirenz and midazolam: Efavirenz activates the CYP3A-mediated midazolam 1′-hydroxylation in vitro
-
PMID: 22019630
-
Keubler A, Weiss J, Haefeli WE, Mikus G, Burhenne J. Drug interaction of efavirenz and midazolam: efavirenz activates the CYP3A-mediated midazolam 1′-hydroxylation in vitro. Drug Metab Dispos. 2012; 40: 178-182. doi: 10.1124/dmd.111.042879 PMID: 22019630
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 178-182
-
-
Keubler, A.1
Weiss, J.2
Haefeli, W.E.3
Mikus, G.4
Burhenne, J.5
-
44
-
-
79251581020
-
The art of microRNA research
-
PMID: 21252150
-
Van Rooij E. The art of microRNA research. Circ Res. 2011; 108: 219-234. doi: 10.1161/CIRCRESAHA.110.227496 PMID: 21252150
-
(2011)
Circ Res
, vol.108
, pp. 219-234
-
-
Van Rooij, E.1
-
45
-
-
64049102360
-
Dynamic localization of hepatocellular transporters in health and disease
-
PMID: 19058304
-
Roma MG, Crocenzi FA, Mottino AD. Dynamic localization of hepatocellular transporters in health and disease. World J Gastroenterol. 2008; 14: 6786-6801. PMID: 19058304
-
(2008)
World J Gastroenterol
, vol.14
, pp. 6786-6801
-
-
Roma, M.G.1
Crocenzi, F.A.2
Mottino, A.D.3
-
46
-
-
84881353168
-
Genistein down-regulates miR-223 expression in pancreatic cancer cells
-
PMID: 23834147
-
Ma J, Cheng L, Liu H, Zhang J, Shi Y, Zeng F, et al. Genistein down-regulates miR-223 expression in pancreatic cancer cells. Curr Drug Targets. 2013; 14: 1150-1156. PMID: 23834147
-
(2013)
Curr Drug Targets
, vol.14
, pp. 1150-1156
-
-
Ma, J.1
Cheng, L.2
Liu, H.3
Zhang, J.4
Shi, Y.5
Zeng, F.6
-
47
-
-
65349184457
-
Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner
-
PMID: 19297428
-
Li Y, Ross-Viola JS, Shay NF, Moore DD, Ricketts ML. Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner. J Nutr. 2009; 139: 898-904. doi: 10.3945/jn.108.103572 PMID: 19297428
-
(2009)
J Nutr
, vol.139
, pp. 898-904
-
-
Li, Y.1
Ross-Viola, J.S.2
Shay, N.F.3
Moore, D.D.4
Ricketts, M.L.5
-
48
-
-
84873033456
-
Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury
-
PMID: 22716961
-
Zhang T, Wang F, Xu HX, Yi L, Qin Y, Chang H, et al. Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury. Br J Nutr. 2013; 109: 223-235. doi: 10.1017/S0007114512001110 PMID: 22716961
-
(2013)
Br J Nutr
, vol.109
, pp. 223-235
-
-
Zhang, T.1
Wang, F.2
Xu, H.X.3
Yi, L.4
Qin, Y.5
Chang, H.6
-
49
-
-
84902967582
-
Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity
-
PMID: 24685904
-
Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, et al. Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity. Toxicology. 2014; 320: 46-55. doi: 10.1016/j.tox.2014.03.007 PMID: 24685904
-
(2014)
Toxicology
, vol.320
, pp. 46-55
-
-
Arias, A.1
Rigalli, J.P.2
Villanueva, S.S.3
Ruiz, M.L.4
Luquita, M.G.5
Perdomo, V.G.6
-
50
-
-
34548079796
-
High-dose acetaminophen inhibits the lethal effect of doxorubicin in HepG2 cells: The role of P-glycoprotein and mitogen-activated protein kinase p44/p42 pathway
-
Manov I, Bashenko Y, Eliaz-Wolkowicz A, Mizrahi M, Liran O, Iancu TC. High-dose acetaminophen inhibits the lethal effect of doxorubicin in HepG2 cells: the role of P-glycoprotein and mitogen-activated protein kinase p44/p42 pathway. J Pharmacol Exp Ther. 2007; 332: 1013-1022.
-
(2007)
J Pharmacol Exp Ther
, vol.332
, pp. 1013-1022
-
-
Manov, I.1
Bashenko, Y.2
Eliaz-Wolkowicz, A.3
Mizrahi, M.4
Liran, O.5
Iancu, T.C.6
-
51
-
-
84880805730
-
Steroidal saponin of Trillium tschonoskii. Reverses multidrug resistance of hepatocellular carcinoma
-
PMID: 23786867
-
Wang H, Zhai Z, Li N, Jin H, Chen J, Yuan S, et al. Steroidal saponin of Trillium tschonoskii. Reverses multidrug resistance of hepatocellular carcinoma. Phytomedicine. 2013; 20: 985-991. doi: 10.1016/j.phymed.2013.04.014 PMID: 23786867
-
(2013)
Phytomedicine
, vol.20
, pp. 985-991
-
-
Wang, H.1
Zhai, Z.2
Li, N.3
Jin, H.4
Chen, J.5
Yuan, S.6
-
52
-
-
35048895704
-
Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs
-
PMID: 17704753
-
Folmer Y, Schneider M, Blum HE, Hafkemeyer P. Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs. Cancer Gene Ther. 2007; 14: 875-884. PMID: 17704753
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 875-884
-
-
Folmer, Y.1
Schneider, M.2
Blum, H.E.3
Hafkemeyer, P.4
-
53
-
-
33749441773
-
Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4
-
PMID: 11741214
-
Achira M, Suzuki H, Ito K, Sugiyama Y. Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4. AAPS PharmSci. 1999; 1: E18. PMID: 11741214
-
(1999)
AAPS PharmSci
, vol.1
, pp. E18
-
-
Achira, M.1
Suzuki, H.2
Ito, K.3
Sugiyama, Y.4
-
54
-
-
0019966544
-
Growth of human hepatoma cell lines with differentiated functions in chemically defined medium
-
PMID: 6286115
-
Nakabayashi H, Taketa K, Miyano K, Yamane T, Sato J. Growth of human hepatoma cell lines with differentiated functions in chemically defined medium. Cancer Res. 1982; 42: 3858-3863. PMID: 6286115
-
(1982)
Cancer Res
, vol.42
, pp. 3858-3863
-
-
Nakabayashi, H.1
Taketa, K.2
Miyano, K.3
Yamane, T.4
Sato, J.5
-
55
-
-
51049104524
-
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
-
PMID: 18645025
-
Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF, et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther. 2008; 7: 2152-2159. doi: 10.1158/1535-7163.MCT-08-0021 PMID: 18645025
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2152-2159
-
-
Kovalchuk, O.1
Filkowski, J.2
Meservy, J.3
Ilnytskyy, Y.4
Tryndyak, V.P.5
Chekhun, V.F.6
-
56
-
-
84869866890
-
MicroRNA and cancer
-
PMID: 23102669
-
Jansson MD, Lund AH. MicroRNA and cancer. Mol Oncol. 2012; 6: 590-610. doi: 10.1016/j.molonc.2012.09.006 PMID: 23102669
-
(2012)
Mol Oncol
, vol.6
, pp. 590-610
-
-
Jansson, M.D.1
Lund, A.H.2
|