Conditional knock-out reveals a requirement for O-Linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis

Journal of Biological Chemistry

Volumn 290, Issue 11, 2015, Pages 7097-7113

  Keembiyehetty, Chithra ^a   Love, Dona C ^a   Harwood, Katryn R ^a   Gavrilova, Oksana ^a   Comly, Marcella E ^a   Hanover, John A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; GENES; GLUCOSE; INSULIN; MAMMALS; MEDICAL PROBLEMS; METABOLISM; NUTRITION; PHYSIOLOGY; TRANSCRIPTION;

ENZYMATIC ACTIVITIES; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; METABOLIC PROFILING; MOUSE EMBRYONIC FIBROBLASTS; TRANSCRIPTOME ANALYSIS;

ANIMALS;

ACETYLGLUCOSAMINIDASE; GLUCOSE; GLYCOGEN; INSULIN; TRANSCRIPTOME; BETA N ACETYLHEXOSAMINIDASE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HEXOSAMINIDASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME PHOSPHORYLATION; FEMALE; FETUS; FIBROBLAST; GENE DISRUPTION; GENETIC TRANSCRIPTION; GENOTYPE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE UTILIZATION; GLYCOGEN LIVER LEVEL; GROWTH; HETEROZYGOSITY; HOMEOSTASIS; HYPERLEPTINEMIA; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; KNOCKOUT MOUSE; LETHALITY; LIPID DIET; LIPID STORAGE; MALE; METABOLISM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OGA GENE; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE; ANIMAL; CELL CULTURE; ETIOLOGY; GENE INACTIVATION; GENETICS; HUMAN; NEWBORN; PERINATAL DEATH; PREGNANCY; PUERPERIUM;

ANIMALIA; MUS;

ANIMALS; ANIMALS, NEWBORN; BETA-N-ACETYLHEXOSAMINIDASES; CELLS, CULTURED; FEMALE; GENE KNOCKOUT TECHNIQUES; GLUCOSE TOLERANCE TEST; GLYCOGEN SYNTHASE KINASE 3; HOMEOSTASIS; HUMANS; INSULIN; MICE; MICE, KNOCKOUT; PERINATAL DEATH; POSTPARTUM PERIOD; PREGNANCY;

EID: 84924898037     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.617779     Document Type: Article

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