The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice

EMBO Journal

Volumn 34, Issue 6, 2015, Pages 748-758

  Li, Ziwei ^a   Yu, Juehua ^b   Hosohama, Linzi ^a   Nee, Kevin ^a   Gkountela, Sofia ^a   Chaudhari, Sonal ^a   Cass, Ashley A ^a   Xiao, Xinshu ^a   Clark, Amander T ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

conditional knockout; germline absence; PGC specification; PRMT5; splicing

Indexed keywords

PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; UNCLASSIFIED DRUG; PRDM1 PROTEIN, MOUSE; PRIMER DNA; PROTEIN METHYLTRANSFERASE; SKB1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BIOINFORMATICS; CELL CYCLE; CELL SPECIFICITY; CELL SURVIVAL; CONTROLLED STUDY; DNA METHYLATION; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ERYTHROID CELL; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; LEYDIG CELL; MALE; MOUSE; NEURAL STEM CELL; NONHUMAN; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA SPLICING; ANIMAL; BIOLOGY; CELL DIFFERENTIATION; CYTOLOGY; ENZYMOLOGY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETIC EPIGENESIS; GENETICS; GENOTYPE; GERM CELL; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SPLICEOSOME; WESTERN BLOTTING;

MAMMALIA; MURINAE; MUS;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; COMPUTATIONAL BIOLOGY; DNA METHYLATION; DNA PRIMERS; EPIGENESIS, GENETIC; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKOUT TECHNIQUES; GENOTYPE; GERM CELLS; MICE; PROTEIN METHYLTRANSFERASES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, RNA; SPLICEOSOMES; TRANSCRIPTION FACTORS;

EID: 84924853516     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201489319     Document Type: Article

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