Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency

Genes and Development

Volumn 24, Issue 24, 2010, Pages 2772-2777

  Tee, Wee Wei ^a   Pardo, Mercedes ^b   Theunissen, Thorold W ^a   Yu, Lu ^b   Choudhary, Jyoti S ^b   Hajkova, Petra ^c   Surani, M Azim ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Arginine methyltransferase; Embryonic stem cells; Epigenetics; H2A; Pluripotency

Indexed keywords

ENZYME; HISTONE H2A; MEP50 PROTEIN; PRMT5 PROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL PLURIPOTENCY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CYTOPLASM; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE REPRESSION; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CYTOPLASM; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONES; METHYLATION; MICE; PLURIPOTENT STEM CELLS; PROTEIN METHYLTRANSFERASES;

EID: 78650212707     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.606110     Document Type: Article

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