PRMT5 Protects Genomic Integrity during Global DNA Demethylation in Primordial Germ Cells and Preimplantation Embryos

Molecular Cell

Volumn 56, Issue 4, 2014, Pages 564-579

  Kim, Shinseog ^a,b   Günesdogan, Ufuk ^a,b   Zylicz, Jan J ^a,b   Hackett, Jamie A ^a,b   Cougot, Delphine ^a,b   Bao, Siqin ^a,c   Lee, Caroline ^a,b   Dietmann, Sabine ^b   Allen, George E ^a   Sengupta, Roopsha ^a,b   Surani, M Azim ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c INNER MONGOLIA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; HISTONE H2A; HISTONE H4; KI 67 ANTIGEN; METHYLTRANSFERASE; PIWI INTERACTING RNA; PRMT5 PROTEIN; UNCLASSIFIED DRUG; HISTONE; PROTEIN METHYLTRANSFERASE; SKB1 PROTEIN, MOUSE; TRANSPOSON;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CHROMATIN; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DNA METHYLATION; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; FEMALE; FEMALE STERILITY; HISTONE MODIFICATION; MALE; MOUSE; NONHUMAN; PREIMPLANTATION EMBRYO; PRIMORDIAL GERM CELL; PROTEIN LOCALIZATION; SOMATIC CELL; TRANSPOSON; UPREGULATION; ANIMAL; BLASTOCYST; CELL CULTURE; CYTOLOGY; ENZYMOLOGY; GENOMIC INSTABILITY; METABOLISM; OVUM; PHYSIOLOGY; PROTEIN PROCESSING; SPERMATOZOON; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; BLASTOCYST; CELLS, CULTURED; DNA DAMAGE; DNA METHYLATION; DNA TRANSPOSABLE ELEMENTS; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; FEMALE; GENOMIC INSTABILITY; HISTONES; MALE; MICE, TRANSGENIC; OVUM; PROTEIN METHYLTRANSFERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SPERMATOZOA;

EID: 84912103187     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.10.003     Document Type: Article

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