Ligand-enabled β-C-H arylation of α-amino acids using a simple and practical auxiliary

Journal of the American Chemical Society

Volumn 137, Issue 9, 2015, Pages 3338-3351

  Chen, Gang ^a   Shigenari, Toshihiko ^a   Jain, Pankaj ^a   Zhang, Zhipeng ^a   Jin, Zhong ^a   He, Jian ^a   Li, Suhua ^a   Mapelli, Claudio ^b   Miller, Michael M ^b   Poss, Michael A ^b   Scola, Paul M ^b   Yeung, Kap Sun ^b   Yu, Jin Quan ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; AROMATIC COMPOUNDS; ATOMS; CARBOXYLIC ACIDS; CHEMICAL ACTIVATION; CHEMICAL REACTIONS; LIGANDS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ALPHA-AMINO ACIDS; ASYMMETRIC SYNTHESIS; BIOACTIVE MOLECULES; CARBOXYLIC ACID DERIVATIVES; CHIRAL BIS(OXAZOLINE) LIGANDS; FUNCTIONALIZATIONS; GRAM-SCALE SYNTHESIS; UNNATURAL AMINO ACIDS;

REACTION KINETICS;

ALIPHATIC CARBOXYLIC ACID; AMINO ACID; CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; HYDROGEN; LIGAND; PALLADIUM; PHENYLALANINE; ALANINE; PYRIDINE; PYRIDINE DERIVATIVE;

ARTICLE; ARYLATION; ASYMMETRIC SYNTHESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; MEDICINAL CHEMISTRY; MOLECULE; ONE POT SYNTHESIS; CATALYSIS; CHEMISTRY; SYNTHESIS;

ALANINE; AMINO ACIDS; CARBOXYLIC ACIDS; CATALYSIS; CHEMISTRY TECHNIQUES, SYNTHETIC; HYDROGEN; LIGANDS; PALLADIUM; PHENYLALANINE; PYRIDINES;

EID: 84924706379     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja512690x     Document Type: Article

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