Hot Melt Extruded Amorphous Solid Dispersion of Posaconazole with Improved Bioavailability: Investigating Drug-Polymer Miscibility with Advanced Characterisation

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Fule, Ritesh ^a   Amin, Purnima ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MACROGOL 400; POLOXAMER; POSACONAZOLE; TOCOFERSOLAN; POLYMER; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DISPERSION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MISCIBILITY; MOLECULAR DYNAMICS; NONHUMAN; PHYSICAL CHEMISTRY; PLASMA CONCENTRATION-TIME CURVE; RAT; SOLID; SOLUBILIZATION; ANIMAL; ATOMIC FORCE MICROSCOPY; BIOAVAILABILITY; BLOOD; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; HEAT; HUMAN; INFRARED SPECTROSCOPY; RAMAN SPECTROMETRY; SOLUBILITY; TIME; WISTAR RAT; X RAY DIFFRACTION;

ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG STABILITY; HOT TEMPERATURE; HUMANS; MALE; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; POLYMERS; RATS, WISTAR; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN; TIME FACTORS; TRIAZOLES; X-RAY DIFFRACTION;

EID: 84924682138     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/146781     Document Type: Article

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