In vitro anti-telomerase activity of novel lycopene-loaded nanospheres in the human leukemia cell line K562

Pharmacognosy Magazine

Volumn 10, Issue 37, 2014, Pages S157-S163

  Gharib, Amir ^a   Faezizadeh, Zohreh ^a  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Apoptosis; K562; lycopene; nanosphere; telomerase

Indexed keywords

LYCOPENE; NANOSPHERE; TELOMERASE;

ANTINEOPLASTIC ACTIVITY; ANTITELOMERASE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG FORMULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; K562 CELL LINE; MTT ASSAY; NANOENCAPSULATION; PARTICLE SIZE; PHYSICAL PARAMETERS; POLYDISPERSITY INDEX; PRECIPITATION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; ZETA POTENTIAL;

EID: 84924536097     PISSN: 09731296     EISSN: 09764062     Source Type: Journal    
DOI: 10.4103/0973-1296.127368     Document Type: Article

References (32)

1. Tian X, Chen B, Liu X. Telomere and telomerase as targets for cancer therapy. Appl Biochem Biotechnol 2010;160:1460-72.
2. Cheung AL, Deng W. Telomere dysfunction, genome instability and cancer. Front Biosci 2008;13:2075-90.
3. Harley CB. Telomerase and cancer therapeutics. Nat Rev Cancer 2008;8:167-79.
4. Zimmermann S, Martens UM. Telomeres and telomerase as targets for cancer therapy. Cell Mol Life Sci 2007;64:906-21.
5. Huang ST, Wang CY, Yang RC, Chu CJ, Wu HT, Pang JH. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Phytomedicine 2010;17:47-54.
6. Ji ZN, Ye WC, Liu GQ, Huang Y. Inhibition of telomerase activity and bcl-2 expression in berbamine-induced apoptosis in HL-60 cells. Planta Med 2002;68:596-600.
7. Wang X, Hao MW, Dong K, Lin F, Ren JH, Zhang HZ. Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression. Arch Pharm Res 2009;32:1263-9.
8. Lin SC, Li WC, Shih JW, Hong KF, Pan YR, Lin JJ. The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cells. Cancer Lett 2006;236:80-8.
9. Ramachandran C, Fonseca HB, Jhabvala P, Escalon EA, Melnick SJ. Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line. Cancer Lett 2002;184:1-6.
10. Moon DO, Kim MO, Choi YH, Lee HG, Kim ND, Kim GY. Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT. FEBS Lett 2008;582:3367-73.
11. Moon DO, Kim MO, Lee JD, Choi YH, Kim GY. Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells. Cancer Lett 2009;286:172-9.
12. Park SE, Park C, Kim SH, Hossain MA, Kim MY, Chung HY, et al. Korean red ginseng extract induces apoptosis and decreases telomerase activity in human leukemia cells. J Ethnopharmacol 2009;121:304-12.
13. Park DI, Lee JH, Moon SK, Kim CH, Lee YT, Cheong J, et al. Induction of apoptosis and inhibition of telomerase activity by aqueous extract from Platycodon grandiflorum in human lung carcinoma cells. Pharmacol Res 2005;51:437-43.
14. Gerster H. The potential role of lycopene for human health. J Am Coll Nutr 1997;16:109-26.
15. Nahum A, Hirsch K, Danilenko M, Watts CK, Prall OW, Levy J, et al. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes. Oncogene 2001;20:3428-36.
16. Narisawa T, Fukaura Y, Hasebe M, Ito M, Aizawa R, Murakoshi M, et al. Inhibitory effects of natural carotenoids, alpha-carotene, beta-carotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats. Cancer Lett 1996;107:137-42.
17. Gouranton E, Yazidi CE, Cardinault N, Amiot MJ, Borel P, Landrier JF. Purified low-density lipoprotein and bovine serum albumin efficiency to internalise lycopene into adipocytes. Food Chem Toxicol 2008;46:3832-6.
18. Singh M, Bhatnagar P, Srivastava AK, Kumar P, Shukla Y, Gupta KC. Enhancement of cancer chemosensitization potential of cisplatin by tea polyphenols poly (lactide-co-glycolide) nanoparticles. J Biomed Nanotechnol 2011;7:202.
19. Ranjan AP, Mukerjee A, Helson L, Vishwanatha JK. Scale up, optimization and stability analysis of curcumin C3 complex-loaded nanoparticles for cancer therapy. J Nanobiotechnology 2012;10:38.
20. Zhou XL, He JT, Du HJ, Fan YY, Wang Y, Zhang HX, et al. Pharmacokinetic and pharmacodynamic profiles of recombinant human erythropoietin-loaded poly (lactic-co-glycolic acid) microspheres in rats. Acta Pharmacol Sin 2012;33:137-44.
21. Punfa W, Yodkeeree S, Pitchakarn P, Ampasavate C, Limtrakul P. Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells. Acta Pharmacol Sin 2012;33:823-31.
22. Gharib A, Faezizadeh Z, Mohammad Asghari H. Preparation and antifungal activity of spray-dried amphotericin B-loaded nanospheres. Daru 2011;19:351-5.
23. Salman H, Bergman M, Djaldetti M, Bessler H. Lycopene affects proliferation and apoptosis of four malignant cell lines. Biomed Pharmacother 2007;61:366-9.
24. Yeum KJ, Ahn SH, Rupp de Paiva SA, Lee-Kim YC, Krinsky NI, Russell RM. Correlation between carotenoid concentrations in serum and normal breast adipose tissue of women with benign breast tumor or breast cancer. J Nutr 1998;128:1920-6.
25. Zhang X, Wang Q, Neil B, Chen X. Effect of lycopene on androgen receptor and prostate-specific antigen velocity. Chin Med J (Engl) 2010;123:2231-6.
26. Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
27. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
28. Safdar A, Ma J, Saliba F, Dupont B, Wingard JR, Hachem RY, et al. Drug-induced nephrotoxicity caused by amphotericin B lipid complex and liposomal amphotericin B: A review and meta-analysis. Medicine (Baltimore) 2010;89:236-44.
29. Vyas SP, Gupta S. Optimizing efficacy of amphotericin B through nanomodification. Int J Nanomedicine 2006;1:417-32.
30. Das S, Suresh PK, Desmukh R. Design of Eudragit RL 100 nanoparticles by nanoprecipitation method for ocular drug delivery. Nanomedicine 2010;6:318-23.
31. Giovannucci E, Rimm EB, Liu Y, Stampfer MJ, Willett WC. A prospective study of tomato products, lycopene, and prostate cancer risk. J Natl Cancer Inst 2002;94:391-8.
32. Faezizadeh Z, Mesbah-Namin SA, Allameh A. The effect of silymarin on telomerase activity in the human leukemia cell line K562. Planta Med 2012;78:899-902.