Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells

Cancer Letters

Volumn 286, Issue 2, 2009, Pages 172-179

  Moon, Dong Oh ^a   Kim, Mun Ock ^a   Lee, Jae Dong ^b   Choi, Yung Hyun ^c   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Pusan National University   (South Korea)

^c Dong Eui University   (South Korea)

Author keywords

Akt; Butein; c Myc; hTERT; Telomerase

Indexed keywords

BUTEIN; CD11B ANTIGEN; MYC PROTEIN; PROTEIN KINASE B; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN TRANSPORT; TRANSCRIPTION REGULATION; UPREGULATION;

ANTIGENS, CD11B; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHALCONES; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HL-60 CELLS; HUMANS; K562 CELLS; LEUKEMIA; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERASE; TRANSCRIPTION, GENETIC; U937 CELLS;

EID: 71549172492     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.05.028     Document Type: Article

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