Effect of lycopene on androgen receptor and prostate-specific antigen velocity

Chinese Medical Journal

Volumn 123, Issue 16, 2010, Pages 2231-2236

  Zhang, Xin ^a   Wang, Qi ^b   Barber, Neil ^c   Chen, Xiao ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Androgen receptor element; Lncap; Lycopene; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR; LYCOPENE; PROSTATE SPECIFIC ANTIGEN;

AGED; ANDROGEN RESPONSIVE ELEMENT; ARTICLE; CELL STRAIN LNCAP; CLINICAL ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA SYNTHESIS INHIBITION; EXTERNAL BEAM RADIOTHERAPY; GENE EXPRESSION; GROWTH INHIBITION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; PHASE 1 CLINICAL TRIAL; PROSTATE CANCER; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; WATCHFUL WAITING; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; ANTIOXIDANTS; BLOTTING, WESTERN; CAROTENOIDS; CELL LINE, TUMOR; DIETARY SUPPLEMENTS; FURANS; GENE EXPRESSION REGULATION; HUMANS; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; PILOT PROJECTS; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN;

EID: 77956114588     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.16.014     Document Type: Article

References (20)

1. Wingo PA, Cardinez CJ, Landis SH, Greenlee RT, Ries LA, Anderson RN, et al. Long-term trends in cancer mortality in the United States, 1930-1998. Cancer 2003; 97: 3133-3275.
2. Ames BN, Shigenaga MK, Hagan TM. Oxidants, antioxidants and the degenerative diseases of aging. Proc Natl Acad Sci U S A 1993; 90: 7915-7922.
3. Barber NJ, Barber J. Lycopene and prostate cancer. Prostate Cancer Prostatic Dis 2002; 5: 6-12.
4. Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams AW, Moore BJ, et al. Cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomakers Prev 1996; 5: 823-833.
5. Haenszel W, Kurihara M. Studies of Japanese migrants. Mortality from cancer and other disease among Japanese in the United States. J Natl Cancer Inst 1968; 35: 291-297.
6. Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC. Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst 1995; 87: 1767-1776.
7. Gann PH, Ma J, Giovannucci E, Willett W, Sacks FM, Hennekens CH, et al. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 1999; 59: 1225-1230.
8. Ripple MO, Henry WF, Rago RP, Wilding G. Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells. J Natl Cancer Inst 1997; 89: 40-48.
9. Obermüller-Jevic UC, Olano-Martin E, Corbacho AM, Eiserich JP, van der Vliet A, Valacchi G, et al. Lycopene inhibits the growth of normal human prostate epithelial cells in vitro. J Nutr 2003; 133: 3356-3360.
10. Mucci LA, Tamimi R, Lagiou P, Trichopoulou A, Benetou V, Spanos E, et al. Are dietary influences on the risk of prostate cancer mediated through the insulin-like growth factor system? BJU Int 2001; 87: 814-820.
11. Zhang LX, Cooney RV, Bertram JS. Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action. Carcinogenesis 1991; 12: 2109-2104.
12. Pastori M, Pfander H, Boscoboinik D, Azzi A. Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate cancer cells. Biochem Biophys Res Commun 1998; 250: 582-585.
13. Kotake-Nara E, Kushiro M, Zhang H, Sugawara T, Miyashita K, Nagao A. Carotenoids affect proliferation of human prostate cancer cells. J Nutr 2001; 131: 3303-3306.
14. Kim L, Rao AV, Rao LG. Effect of lycopene on prostate LNCaP cancer cells in culture. J Med Food 2002; 5: 181-187.
15. Tong Q, Zhao J, Chen Z, Zeng F, Lu G. Effects of blocking androgen receptor expression with specific hammerhead ribozyme on in vitro growth of prostate cancer cell line. Chin Med J 2003; 116: 1515-1518.
16. Yu SQ, Han BM, Shao Y, Wu JT, Zhao FJ, Liu HT, et al. Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo. Chin Med J 2009; 122: 2779-2783.
17. Hayward SW, Del Buono R, Deshpande N, Hall PA. A functional model of adult human prostate epithelium. The role of androgens and stroma in architectural organization and the maintenance of differentiated secretory function. J Cell Sci 1992; 102: 361-372.
18. Kucuk O, Sarkar FH, Sakr W, Djuric Z, Pollak MN, Khachik F, et al. Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. Cancer Epidemiol Biomarkers Prev 2001; 10: 861-868.
19. Chen L, Stacewicz-Sapuntzakis M, Duncan C, Sharifi R, Ghosh L, van Breemen R, et al. Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole food intervention. J Natl Cancer Inst 2001; 93: 1872-1879.
20. Ansari MS, Gupta NP. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int 2003; 92: 375-378.