-
1
-
-
77953384502
-
Novel targeted drug therapies for the treatment of childhood acute leukemia
-
Brown, P, Hunger, SP, Smith, FO, Carroll, WL, and Reaman, GH: Novel targeted drug therapies for the treatment of childhood acute leukemia. Expert Rev Hematol 2, 145-158, 2009.
-
(2009)
Expert Rev Hematol
, vol.2
, pp. 145-158
-
-
Brown, P.1
Hunger, S.P.2
Smith, F.O.3
Carroll, W.L.4
Reaman, G.H.5
-
2
-
-
24644523642
-
Flavonoid compounds in maintenance of prostate health and prevention and treatment of cancer
-
Brown, DM, Kelly, GE, and Husband, AJ: Flavonoid compounds in maintenance of prostate health and prevention and treatment of cancer. Mol Biotechnol 30, 253-270, 2005.
-
(2005)
Mol Biotechnol
, vol.30
, pp. 253-270
-
-
Brown, D.M.1
Kelly, G.E.2
Husband, A.J.3
-
3
-
-
0034807826
-
Dietary agents in cancer prevention: Flavonoids and isoflavonoids
-
Birt, DF, Hendrich, S, and Wang, W: Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther 90, 157-177, 2001.
-
(2001)
Pharmacol Ther
, vol.90
, pp. 157-177
-
-
Birt, D.F.1
Hendrich, S.2
Wang, W.3
-
4
-
-
0028244459
-
The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in jurkat T-leukemia cells
-
Spinozzi, F, Pagliacci, MC, Migliorati, G, Moraca, R, Grignani, F, et al.: The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in jurkat T-leukemia cells. Leuk Res 18, 431-439, 1994.
-
(1994)
Leuk Res
, vol.18
, pp. 431-439
-
-
Spinozzi, F.1
Pagliacci, M.C.2
Migliorati, G.3
Moraca, R.4
Grignani, F.5
-
5
-
-
33845753470
-
Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling
-
Shen, J, Tai, YC, Zhou, J, Wong, CHS, Cheang, PT, et al.: Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling. Exp Hematol 35, 75-83, 2007.
-
(2007)
Exp Hematol
, vol.35
, pp. 75-83
-
-
Shen, J.1
Tai, Y.C.2
Zhou, J.3
Wong, C.H.S.4
Cheang, P.T.5
-
6
-
-
0028985934
-
Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases
-
Uckun, FM, Evans, WE, Forsyth, CJ, Waddick, KG, et al.: Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases. Science 267, 886-891, 1995.
-
(1995)
Science
, vol.267
, pp. 886-891
-
-
Uckun, F.M.1
Evans, W.E.2
Forsyth, C.J.3
Waddick, K.G.4
-
7
-
-
70349573116
-
The effect of genistein aglycone on cancer and cancer risk: A review of in vitro, preclinical, and clinical studies
-
Taylor, C. K., Levy, R. M., Elliott, J. C., and Burnett, B. P., The effect of genistein aglycone on cancer and cancer risk: A review of in vitro, preclinical, and clinical studies, Nutr Rev 67, 398-415, 2009.
-
(2009)
Nutr Rev
, vol.67
, pp. 398-415
-
-
Taylor, C.K.1
Levy, R.M.2
Elliott, J.C.3
Burnett, B.P.4
-
8
-
-
20144387818
-
Baicalein, a component of scutellaria radix from huang-lian-jie-du-tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells
-
Ma, Z, Otsuyama, K, Liu, S, Abroun, S, Ishikawa, H, et al.: Baicalein, a component of scutellaria radix from huang-lian-jie-du-tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. Blood 105, 3312-3318, 2005.
-
(2005)
Blood
, vol.105
, pp. 3312-3318
-
-
Ma, Z.1
Otsuyama, K.2
Liu, S.3
Abroun, S.4
Ishikawa, H.5
-
9
-
-
75749108938
-
Flavopiridol, fludarabine, and rituximab in mantle cell lymphoma and indolent B-cell lymphoproliferative disorders
-
Lin, TS, Blum, KA, Fischer, DB,Mitchell, SM, Ruppert, AS, et al.: Flavopiridol, fludarabine, and rituximab in mantle cell lymphoma and indolent B-cell lymphoproliferative disorders. J Clin Oncol 28, 418-423, 2010.
-
(2010)
J Clin Oncol
, vol.28
, pp. 418-423
-
-
Lin, T.S.1
Blum, K.A.2
Fischer, D.B.3
Mitchell, S.M.4
Ruppert, A.S.5
-
10
-
-
73349096649
-
Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease
-
Lin, TS, Ruppert, AS, Johnson, AJ, Fischer, B, Heerema, NA, et al.: Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease. J Clin Oncol 27, 6012-6018, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6012-6018
-
-
Lin, T.S.1
Ruppert, A.S.2
Johnson, A.J.3
Fischer, B.4
Heerema, N.A.5
-
11
-
-
67650712277
-
The anti-cancer drug, phenoxodiol, kills primary myeloid and lymphoid leukemic blasts and rapidly proliferating T cells
-
Herst,PM, Davis, JE,Neeson, P, Berridge, MV, and Ritchie, DS: The anti-cancer drug, phenoxodiol, kills primary myeloid and lymphoid leukemic blasts and rapidly proliferating T cells. Haematologica 94, 928-934, 2009.
-
(2009)
Haematologica
, vol.94
, pp. 928-934
-
-
Herst, P.M.1
Davis, J.E.2
Neeson, P.3
Berridge, M.V.4
Ritchie, D.S.5
-
12
-
-
33947595802
-
Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cells
-
Plochmann, K, Korte, G, Koutsilieri, E, Richling, E, Riederer, P, et al.: Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cells. Arch Biochem Biophys 460, 1-9, 2007.
-
(2007)
Arch Biochem Biophys
, vol.460
, pp. 1-9
-
-
Plochmann, K.1
Korte, G.2
Koutsilieri, E.3
Richling, E.4
Riederer, P.5
-
13
-
-
71049131644
-
Proteomics, pathway array and signaling network-based medicine in cancer
-
Zhang, DY, Ye, F, Gao, L, Liu, X, Zhao, X, et al.: Proteomics, pathway array and signaling network-based medicine in cancer. Cell Div 4, 20, 2009.
-
(2009)
Cell Div
, vol.4
, pp. 20
-
-
Zhang, D.Y.1
Ye, F.2
Gao, L.3
Liu, X.4
Zhao, X.5
-
14
-
-
8444220391
-
Quality evaluation of commercial extracts of Scutellaria baicalensis
-
Ye, F, Wang, H, Jiang, S,Wu, J, Shao, J, et al.: Quality evaluation of commercial extracts of Scutellaria baicalensis. Nutr Cancer 49, 217-222, 2004.
-
(2004)
Nutr Cancer
, vol.49
, pp. 217-222
-
-
Ye, F.1
Wang, H.2
Jiang, S.3
Wu, J.4
Shao, J.5
-
15
-
-
70449671065
-
The effect of scutellaria baicalensis on the signaling network in hepatocellular carcinoma cells
-
Ye, F, Che, Y, McMillen, E, Gorski, J, Brodman, D, et al.: The effect of scutellaria baicalensis on the signaling network in hepatocellular carcinoma cells. Nutr Cancer 61, 530-537, 2009.
-
(2009)
Nutr Cancer
, vol.61
, pp. 530-537
-
-
Ye, F.1
Che, Y.2
McMillen, E.3
Gorski, J.4
Brodman, D.5
-
16
-
-
48749117943
-
Multi-targeted therapy of cancer by genistein
-
Banerjee, S, Li, Y, Wang, Z, and Sarkar, FH: Multi-targeted therapy of cancer by genistein. Cancer Lett 269, 226-242, 2008.
-
(2008)
Cancer Lett
, vol.269
, pp. 226-242
-
-
Banerjee, S.1
Li, Y.2
Wang, Z.3
Sarkar, F.H.4
-
17
-
-
70149084736
-
Relationship between structure and antiproliferative, proapoptotic, and differentiation effects of flavonoids on chronic myeloid leukemia cells
-
Ramanouskaya, TV, Smolnykova, VV, and Grinev, V: Relationship between structure and antiproliferative, proapoptotic, and differentiation effects of flavonoids on chronic myeloid leukemia cells. Anticancer Drugs 20, 573-583, 2009.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 573-583
-
-
Ramanouskaya, T.V.1
Smolnykova, V.V.2
Grinev, V.3
-
18
-
-
67650712277
-
The anti-cancer drug, phenoxodiol, kills primary myeloid and lymphoid leukemic blasts and rapidly proliferating T cells
-
Herst,PM, Davis, JE,Neeson, P, Berridge, MV, and Ritchie, DS: The anti-cancer drug, phenoxodiol, kills primary myeloid and lymphoid leukemic blasts and rapidly proliferating T cells. Haematologica 94, 928-934, 2009.
-
(2009)
Haematologica
, vol.94
, pp. 928-934
-
-
Herst, P.M.1
Davis, J.E.2
Neeson, P.3
Berridge, M.V.4
Ritchie, D.S.5
-
19
-
-
33747188963
-
Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells
-
Vargo, MA, Voss, OH, Poustka, F, Cardounel, AJ, Grotewold, E, et al.: Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells. Biochem Pharmacol 72, 681-692, 2006.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 681-692
-
-
Vargo, M.A.1
Voss, O.H.2
Poustka, F.3
Cardounel, A.J.4
Grotewold, E.5
-
20
-
-
59249108657
-
Naringenininduced apoptosis is attenuated by bcl-2 but restored by the small molecule bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells
-
Jin, CY, Park, C, Lee, JH, Chung, KT, Kwon, TK, et al.: Naringenininduced apoptosis is attenuated by bcl-2 but restored by the small molecule bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells. Toxicol in. Vitro 23, 259-265, 2009.
-
(2009)
Toxicol In. Vitro
, vol.23
, pp. 259-265
-
-
Jin, C.Y.1
Park, C.2
Lee, J.H.3
Chung, K.T.4
Kwon, T.K.5
-
21
-
-
33749240336
-
Influence of galangin on HL-60 cell proliferation and survival
-
Bestwick, CS and Milne, L: Influence of galangin on HL-60 cell proliferation and survival. Cancer Lett 243, 80-89, 2006.
-
(2006)
Cancer Lett
, vol.243
, pp. 80-89
-
-
Bestwick, C.S.1
Milne, L.2
-
22
-
-
33750719622
-
Molecular response of leukemia HL-60 cells to genistein treatment, a proteomics study
-
Zhang, D, Tai, YC, Wong, CH, Tai, LK, Koay, ES, et al.: Molecular response of leukemia HL-60 cells to genistein treatment, a proteomics study. Leuk Res 31, 75-82, 2007.
-
(2007)
Leuk Res
, vol.31
, pp. 75-82
-
-
Zhang, D.1
Tai, Y.C.2
Wong, C.H.3
Tai, L.K.4
Koay, E.S.5
-
23
-
-
33947595802
-
Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cell
-
Plochmann, K, Korte, G, Koutsilieri, E, Richling, E, Riederer, P, et l.: Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cell. Arch Biochem Biophys 460, 1-9, 2007.
-
(2007)
Arch Biochem Biophys
, vol.460
, pp. 1-9
-
-
Plochmann, K.1
Korte, G.2
Koutsilieri, E.3
Richling, E.4
Riederer, P.5
-
24
-
-
28744436977
-
Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells
-
Kitagawa, S, Nabekura, T, Takahashi, T, Nakamura, Y, Sakamoto, H, et al.: Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells. Biol Pharm Bull 28, 2274-2278, 2005.
-
(2005)
Biol Pharm Bull
, vol.28
, pp. 2274-2278
-
-
Kitagawa, S.1
Nabekura, T.2
Takahashi, T.3
Nakamura, Y.4
Sakamoto, H.5
-
25
-
-
17144408313
-
The interaction of flavonoids with mitochondria: Effects on energetic processes
-
DortaDJ, Pigoso, AA, Mingatto, FE, Rodrigues, T, Prado, IM, et al.: The interaction of flavonoids with mitochondria: effects on energetic processes. Chem Biol Interact 152, 67-78, 2005.
-
(2005)
Chem Biol Interact
, vol.152
, pp. 67-78
-
-
Dorta, D.J.1
Pigoso, A.A.2
Mingatto, F.E.3
Rodrigues, T.4
Prado, I.M.5
-
26
-
-
0037376894
-
Notch signalling in hematopoiesis
-
Ohishi, K, Katayama, N, Shiku, H, Varnum-Finney, B, and Bernstein, ID: Notch signalling in hematopoiesis. Semin Cell Dev Biol 14, 143-150, 2003.
-
(2003)
Semin Cell Dev Biol
, vol.14
, pp. 143-150
-
-
Ohishi, K.1
Katayama, N.2
Shiku, H.3
Varnum-Finney, B.4
Bernstein, I.D.5
-
27
-
-
70350637386
-
Notch signaling in the hematopoietic system
-
Sandy, AR and Maillard, I: Notch signaling in the hematopoietic system. Expert Opin Biol Ther 9, 1383-1398, 2009.
-
(2009)
Expert Opin Biol Ther
, vol.9
, pp. 1383-1398
-
-
Sandy, A.R.1
Maillard, I.2
-
28
-
-
66149129233
-
Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells
-
Rao, SS, Liberator, J, HardwickCD, Dai JS, et al.: Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells. Cancer Res 69, 3060-3068, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 3060-3068
-
-
Rao, S.S.1
Liberator, J.2
Hardwick, C.D.3
Dai, J.S.4
-
29
-
-
77954423454
-
Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the RB protein
-
Li, GH, Fan, YZ, Liu, XW, Zhang, BF, Yin, DD, et al.: Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the RB protein. Mol Cell Biochem 340, 7-14, 2010.
-
(2010)
Mol Cell Biochem
, vol.340
, pp. 7-14
-
-
Li, G.H.1
Fan, Y.Z.2
Liu, X.W.3
Zhang, B.F.4
Yin, D.D.5
-
30
-
-
77950353000
-
Inhibition of cell proliferation and MAP kinase and akt pathways in oral squamous cell carcinoma by genistein and biochanin A
-
JohnsonT. L., Lai, M. B., Lai, J. C., and Bhushan, A., Inhibition of cell proliferation and MAP kinase and akt pathways in oral squamous cell carcinoma by genistein and biochanin A, Evid Based. Complement. Alternat Med. (2008).
-
(2008)
Evid Based. Complement. Alternat Med.
-
-
Johnson, T.L.1
Lai, M.B.2
Lai, J.C.3
Bhushan, A.4
-
31
-
-
62849109985
-
Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells
-
Gao, J, Tian, J, Lv, Y, Shi, F, Kong, F, et al.: Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells. Cancer Sci 100, 389-395, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 389-395
-
-
Gao, J.1
Tian, J.2
Lv, Y.3
Shi, F.4
Kong, F.5
-
32
-
-
58149235546
-
The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts
-
Nam, TW, Yoo, CI, Kim, HT, Kwon, CH, Park, JY, et al.: The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts. J BoneMinerMetab 26, 551-560, 2008.
-
(2008)
J BoneMinerMetab
, vol.26
, pp. 551-560
-
-
Nam, T.W.1
Yoo, C.I.2
Kim, H.T.3
Kwon, C.H.4
Park, J.Y.5
-
33
-
-
34248157606
-
Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells
-
Shukla, S and Gupta, S: Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells. Cell Cycle 6, 1102-1114, 2007.
-
(2007)
Cell Cycle
, vol.6
, pp. 1102-1114
-
-
Shukla, S.1
Gupta, S.2
-
34
-
-
74949106101
-
The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells
-
Zhou, QM, Wang, S, Zhang, H, Lu, YY, Wang, XF, et al.: The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells. Acta Pharmacol Sin 30, 1648-1658, 2009.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 1648-1658
-
-
Zhou, Q.M.1
Wang, S.2
Zhang Lu H, Y.Y.3
Wang, X.F.4
-
35
-
-
17444390875
-
Baicalein induced cell cycle arrest and apoptosis in human lung squamous carcinoma CH27 cells
-
Lee, HZ, Leung, HW, Lai, MY, and Wu, CH: Baicalein induced cell cycle arrest and apoptosis in human lung squamous carcinoma CH27 cells. Anticancer Res 25, 959-964, 2005.
-
(2005)
Anticancer Res
, vol.25
, pp. 959-964
-
-
Lee, H.Z.1
Leung, H.W.2
Lai, M.Y.3
Wu, C.H.4
-
36
-
-
84873636347
-
Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17beta-estradiol or bisphenol A via the inhibition of cell cycle progression
-
Hwang, KA, Kang, NH, Yi, BR, Lee, HR, Park, MA, et al.: Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17beta-estradiol or bisphenol A via the inhibition of cell cycle progression. Int J Oncol 42, 733-740, 2013.
-
(2013)
Int J Oncol
, vol.42
, pp. 733-740
-
-
Hwang, K.A.1
Kang, N.H.2
Yi, B.R.3
Lee, H.R.4
Park, M.A.5
-
37
-
-
84924456419
-
Effects of baicalein on apoptosis
-
Zhang, Y., Song, L., Cai, L., Wei, R., Hu, H., and Jin, W., Effects of baicalein on apoptosis, cell cycle arres, 2013.
-
(2013)
Cell Cycle Arres
-
-
Zhang, Y.1
Song, L.2
Cai, L.3
Wei, R.4
Hu, H.5
Jin, W.6
-
38
-
-
78049294193
-
The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-kappaB inhibition
-
Vidya Priyadarsini, R, Senthil Murugan, R, Maitreyi, S, Ramalingam, K, Karunagaran, D, et al.: The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-kappaB inhibition. Eur J Pharmacol 649, 84-91, 2010.
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 84-91
-
-
Vidya Priyadarsini, R.1
Senthil Murugan, R.2
Maitreyi, S.3
Ramalingam, K.4
Karunagaran, D.5
-
39
-
-
17444390875
-
Baicalein induced cell cycle arrest and apoptosis in human lung squamous carcinoma CH27 cells
-
Lee, HZ, Leung, HW, Lai, MY, and Wu, CH: Baicalein induced cell cycle arrest and apoptosis in human lung squamous carcinoma CH27 cells. Anticancer Res 25, 959-964, 2005.
-
(2005)
Anticancer Res
, vol.25
, pp. 959-964
-
-
Lee, H.Z.1
Leung, H.W.2
Lai, M.Y.3
Wu, C.H.4
-
40
-
-
0032456061
-
Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells
-
Davis, JN, Singh, B, Bhuiyan, M, and Sarkar, F: Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells. Nutr Cancer 32, 123-131, 1998.
-
(1998)
Nutr Cancer
, vol.32
, pp. 123-131
-
-
Davis, J.N.1
Singh, B.2
Bhuiyan, M.3
Sarkar, F.4
-
41
-
-
74049101564
-
Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells
-
Liu, S, Ma, Z, Cai, H, Li, Q, Rong, W, et al.: Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells. Eur J Haematol 84, 137-144, 2010.
-
(2010)
Eur J Haematol
, vol.84
, pp. 137-144
-
-
Liu, S.1
Ma, Z.2
Cai, H.3
Li, Q.4
Rong, W.5
-
42
-
-
0031595611
-
Genisteininduced G2-M arrest, p21WAF1 upregulation, and apoptosis in a nonsmall-cell lung cancer cell line
-
Lian, F, Bhuiyan, M, Li, YW, Wall, N, Kraut, M, et al.: Genisteininduced G2-M arrest, p21WAF1 upregulation, and apoptosis in a nonsmall-cell lung cancer cell line. Nutr Cancer 31, 184-191, 1998.
-
(1998)
Nutr Cancer
, vol.31
, pp. 184-191
-
-
Lian, F.1
Bhuiyan Li M, Y.W.2
Wall, N.3
Kraut, M.4
|