Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein

Molecular and Cellular Biochemistry

Volumn 340, Issue 1-2, 2010, Pages 7-14

  Li, Guo Hui ^a   Fan, Yu Zhen ^a   Liu, Xiao Wei ^b   Zhang, Bing Fang ^b,c   Yin, Dan Dan ^a,b   He, Fei ^b   Huang, Si Yong ^a   Kang, Zhi Jie ^a   Xu, Heng ^a   Liu, Qiang ^a,b   Wu, Yan Lan ^a   Niu, Xiao Li ^a   Zhang, Li ^a   Liu, Li ^a   Hao, Miao Wang ^a   Han, Hua ^a,b   Liang, Ying Min ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Secretase inhibitor; Acute myeloid leukemia; Apoptosis; Cell proliferation; HL60 cells; Jagged1; Notch

Indexed keywords

BETA ACTIN; GAMMA SECRETASE INHIBITOR; HYBRID PROTEIN; JAGGED1; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; PROTEIN BCL 2; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 5; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CALCIUM BINDING PROTEIN; ENZYME INHIBITOR; HES1 PROTEIN, HUMAN; HES5 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MEMBRANE PROTEIN; MYC PROTEIN; MYC PROTEIN, HUMAN; NOTCH RECEPTOR; REPRESSOR PROTEIN; SECRETASE; SERRATE PROTEINS; SIGNAL PEPTIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL STRAIN HL 60; CELL SURVIVAL; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; ONCOGENE C MYC; PROMYELOCYTIC LEUKEMIA; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL CYCLE; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HELA CELL LINE; HL 60 CELL LINE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME;

AMYLOID PRECURSOR PROTEIN SECRETASES; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CALCIUM-BINDING PROTEINS; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HELA CELLS; HL-60 CELLS; HOMEODOMAIN PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, NOTCH; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 77954423454     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0394-9     Document Type: Article

References (31)

1. S Artavanis-Tsakonas MD Rand RJ Lake 1999 Notch signaling: cell fate control and signal integration in development Science 284 770 776 10.1126/science.284.5415.770 1:CAS:528:DyaK1MXivVKrs7Y%3D 10221902 (Pubitemid 29291335)
2. JM Lee KH Lee M Weidner, et al. 2002 Epstein-barr virus EBNA2 blocks Nur77-mediated apoptosis Proc Natl Acad Sci USA 99 11878 11883 10.1073/pnas.182552499 1:CAS:528:DC%2BD38XntFWqtLY%3D 12195020 (Pubitemid 34994492)
3. M Lucio 2006 Notch signaling Clin Cancer Res 12 1074 1079 10.1158/1078-0432.CCR-05-2570 (Pubitemid 43342494)
4. B De Strooper W Annaert P Cupers, et al. 1999 A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain Nature 398 518 522 10.1038/19083 10206645 (Pubitemid 29177491)
5. K Tamura Y Taniguchi S Minoguchi, et al. 1995 Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H) Curr Biol 5 1416 1423 10.1016/S0960-9822(95)00279-X 1:CAS:528:DyaK28XhtVehuw%3D%3D 8749394 (Pubitemid 3009974)
6. L Wu JC Aster SC Blacklow, et al. 2000 MAML1, a human homologue of drosophila mastermind, is a transcriptional co-activator for NOTCH receptors Nat Genet 26 484 489 10.1038/82644 1:CAS:528:DC%2BD3cXptVWgt70%3D 11101851
7. T Iso L Kedes Y Hamamori 2003 HES and HERP families: multiple effectors of the Notch signaling pathway J Cell Physiol 194 237 255 10.1002/jcp.10208 1:CAS:528:DC%2BD3sXhtFKiurs%3D 12548545 (Pubitemid 36176887)
8. LW Ellisen J Bird DC West, et al. 1991 TAN-1, the human homolog of the drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms Cell 66 649 661 10.1016/0092-8674(91)90111-B 1:CAS:528:DyaK3sXnsVGjsA%3D%3D 1831692
9. SK Ma TS Wan LC Chan 1999 Cytogenetics and molecular genetics of childhood leukemia Hematol Oncol 17 91 105 10.1002/(SICI)1099-1069(199909)17: 3<91::AID-HON643>3.0.CO;2-Y 1:CAS:528:DC%2BD3cXpslaqsA%3D%3D 10641030 (Pubitemid 30094130)
10. AP Weng AA Ferrando W Lee, et al. 2004 Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia Science 306 269 271 10.1126/science.1102160 1:CAS:528:DC%2BD2cXotFWnsbo%3D 15472075 (Pubitemid 39336870)
11. JC Aster L Xu FG Karnell, et al. 2000 Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1 Mol Cell Biol 20 7505 7515 10.1128/MCB.20.20.7505-7515.2000 1:CAS:528: DC%2BD3cXnt1aitrs%3D 11003647
12. L Li LA Milner Y Deng, et al. 1998 The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notchl Immunity 8 43 55 10.1016/S1074-7613(00)80457-4 1:CAS:528:DyaK1cXptVOhtA%3D%3D 9462510 (Pubitemid 28097822)
13. T Schroeder U Just 2000 Notch signalling via RBP-J promotes myeloid differentiation EMBO J 19 2558 2568 10.1093/emboj/19.11.2558 1:CAS:528:DC%2BD3cXkslansbc%3D 10835354
14. S Tohda N Nara 2001 Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells Leuk Lymphoma 42 467 472 10.3109/10428190109064603 1:CAS:528:DC%2BD3MXmtlSltLc%3D 11699411
15. H Kogoshi T Sato T Koyama, et al. 2007 Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells Oncol Rep 18 77 80 1:CAS:528:DC%2BD2sXot1Kmu7k%3D 17549349
16. S Tohda M Murata-Ohsawa S Sakano, et al. 2003 Notch ligands Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines Int J Oncol 22 1073 1079 1:CAS:528: DC%2BD3sXjsVOksrs%3D 12684674
17. S Tohda H Kogoshi N Murakami, et al. 2005 Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells Exp Hematol 33 558 563 10.1016/j.exphem.2005.01.010 1:CAS:528:DC%2BD2MXjsFKhs7w%3D 15850833 (Pubitemid 40592172)
18. LJ Strobl H Höfelmayr C Stein G Marschall M Brielmeier G Laux GW Bornkamm U Zimber-Strobl 1997 Both epstein-barr viral nuclear antigen 2 (EBNA2) and activated Notch1 transactivate genes by interacting with the cellular protein RBP-J kappa Immunobiology 198 299 306 1:CAS:528:DyaK1cXktFajsQ%3D%3D 9442401
19. K Fitzgerald I Greenwald 1995 Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo Development 121 4275 4282 1:CAS:528:DyaK28XhvFWjsg%3D%3D 8575327
20. R Chiaramonte A Basile E Tassi, et al. 2005 A wide role for NOTCH1 signaling in acute leukemia Cancer Lett 219 113 120 10.1016/j.canlet.2004.07.022 1:CAS:528:DC%2BD2MXhtVOqsLk%3D 15694671 (Pubitemid 40203178)
21. A Rangarajan C Talora R Okuyama, et al. 2001 Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation EMBO J 20 3427 3436 10.1093/emboj/20.13.3427 1:CAS:528:DC%2BD3MXlsVCgtrc%3D 11432830 (Pubitemid 32634350)
22. X Sun S Artavanis-Tsakonas 1997 Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in drosophila Development 124 3439 3448 1:CAS:528:DyaK2sXmtlCmuro%3D 9310338
23. V Vas L Szilagyi K Paloczi, et al. 2004 Soluble Jagged-1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self-renewal in a surrogate in vitro assay J Leukoc Biol 75 714 720 10.1189/jlb.1003462 1:CAS:528:DC%2BD2cXivFyrtrw%3D 14742638 (Pubitemid 38405664)
24. B Varnum-Finney LE Purton M Yu, et al. 1998 The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells Blood 91 4084 4091 1:CAS:528:DyaK1cXjsV2isLc%3D 9596653
25. MA Epstein BG Achong YM Barr 1964 Virus particles in cultured lymphoblasts from Burkitt's lymphoma Lancet 1 702 703 10.1016/S0140-6736(64) 91524-7 1:STN:280:DyaF2c%2FmsFKmtw%3D%3D 14107961
26. AL Parks JR Stout SB Shepard, et al. 2006 Structure-function analysis of delta trafficking, receptor binding and signaling in drosophila Genetics 174 1947 1961 10.1534/genetics.106.061630 1:CAS:528:DC%2BD2sXhs1Wgtr4%3D 17028337 (Pubitemid 46011585)
27. AP Weng JM Millholland Y Yashiro-Ohtani, et al. 2006 c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma Genes Dev 20 2096 2109 10.1101/gad.1450406 1:CAS:528:DC%2BD28XosVeltLc%3D 16847353 (Pubitemid 44157460)
28. T Palomero WK Lim DT Odom, et al. 2006 NOTCH1 directly regulates c-Myc and activates a feed-forward-loop transcriptional network promoting leukemic cell growth Proc Natl Acad Sci USA 103 18261 18266 10.1073/pnas.0606108103 1:CAS:528:DC%2BD28XhtlWju7vK 17114293 (Pubitemid 44871646)
29. RA Weinberg 1995 The retinoblastoma protein and cell cycle control Cell 81 323 10.1016/0092-8674(95)90385-2 1:CAS:528:DyaK2MXlsFSrs7k%3D 7736585
30. RP Warrell Jr H de The ZY Wang, et al. 1993 Acute promyelocytic leukemia N Engl J Med 329 177 189 10.1056/NEJM199307153290307 1:CAS:528: DyaK3sXmt1arsL8%3D 8515790 (Pubitemid 23195739)
31. M Murata-Ohsawa S Tohda H Kogoshi, et al. 2005 The Notch ligand, Delta1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells Leuk Res 29 197 203 10.1016/j.leukres.2004.05.020 1:CAS:528:DC%2BD2cXhtVyktb%2FO 15607369 (Pubitemid 39647514)