Transcriptomic analysis and 3d bioengineering of astrocytes indicate rock inhibition produces cytotrophic astrogliosis

Frontiers in Neuroscience

Volumn 9, Issue FEB, 2015, Pages

  O'Shea, Ross D ^a   Lau, Chew L ^b   Zulaziz, Natasha ^a   Maclean, Francesca L ^c   Nisbet, David R ^c   Horne, Malcolm K ^b,d   Beart, Philip M ^b  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^d ST VINCENT S HOSPITAL   (Australia)

Author keywords

Astrocyte; Bioengineering; Cell culture; Cytotrophic phenotype; Rho kinase; Transcriptome

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; F ACTIN; FASUDIL; G ACTIN; HYPOXIA INDUCIBLE FACTOR 1; MOLECULAR MOTOR; POLYCAPROLACTONE; RHO KINASE; TRANSFORMING GROWTH FACTOR BETA;

ACTIN FILAMENT; ANGIOGENESIS; ANIMAL CELL; ANTIBODY LABELING; ASTROCYTE; ASTROCYTOSIS; AUTOPHAGY; BIOENGINEERING; CELL CULTURE; CELL ENGINEERING; CELL MIGRATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTROPHIC ASTROGLIOSIS; DOWN REGULATION; ENZYME INHIBITION; EXTRACELLULAR MATRIX; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; INFLAMMATION; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SIGNAL TRANSDUCTION; TIGHT JUNCTION; TRANSCRIPTOMICS;

EID: 84924413049     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2015.00050     Document Type: Review

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