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Volumn 633, Issue 1-3, 2010, Pages 24-32

Preconditioning protects against oxidative injury involving hypoxia-inducible factor-1 and vascular endothelial growth factor in cultured astrocytes

Author keywords

Desferrioxamine; HIF 1 (hypoxia inducible factor 1) target gene; Neuroprotection; Oxidative stress; Prolyl hydroxylase; Tolerance

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; BENZOIC ACID DERIVATIVE; CYCLOHEXIMIDE; DEFEROXAMINE; ETHYL 3,4 DIHYDROBENZOIC ACID; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 77949917152     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.02.008     Document Type: Article
Times cited : (40)

References (50)
  • 1
    • 0032190580 scopus 로고    scopus 로고
    • Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-beta
    • Behzadian M.A., Wang X.L., Al-Shabrawey M., Caldwell R.B. Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-beta. Glia 1998, 24:216-225.
    • (1998) Glia , vol.24 , pp. 216-225
    • Behzadian, M.A.1    Wang, X.L.2    Al-Shabrawey, M.3    Caldwell, R.B.4
  • 2
    • 0033435198 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
    • Bergeron M., Yu A.Y., Solway K.E., Semenza G.L., Sharp F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 1999, 11:4159-4170.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 4159-4170
    • Bergeron, M.1    Yu, A.Y.2    Solway, K.E.3    Semenza, G.L.4    Sharp, F.R.5
  • 4
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick R.K., McKnight S.L. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001, 294:1337-1340.
    • (2001) Science , vol.294 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 5
    • 0037131271 scopus 로고    scopus 로고
    • Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha
    • Chan D.A., Sutphin P.D., Denko N.C., Giaccia A.J. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha. J. Biol. Chem. 2002, 277:40112-40117.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40112-40117
    • Chan, D.A.1    Sutphin, P.D.2    Denko, N.C.3    Giaccia, A.J.4
  • 6
    • 33748714735 scopus 로고    scopus 로고
    • The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes
    • Chavez J.C., Baranova O., Lin J., Pichiule P. The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J. Neurosci. 2006, 26:9471-9481.
    • (2006) J. Neurosci. , vol.26 , pp. 9471-9481
    • Chavez, J.C.1    Baranova, O.2    Lin, J.3    Pichiule, P.4
  • 7
    • 0035871942 scopus 로고    scopus 로고
    • Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells
    • Chun Y.S., Yeo E.J., Choi E., Teng C.M., Bae J.M., Kim M.S., Park J.W. Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells. Biochem. Pharmacol. 2001, 61:947-954.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 947-954
    • Chun, Y.S.1    Yeo, E.J.2    Choi, E.3    Teng, C.M.4    Bae, J.M.5    Kim, M.S.6    Park, J.W.7
  • 8
    • 0029990439 scopus 로고    scopus 로고
    • Astrocytes protect neurons from hydrogen peroxide toxicity
    • Desagher S., Glowinski J., Premont J. Astrocytes protect neurons from hydrogen peroxide toxicity. J. Neurosci. 1996, 16:2553-2562.
    • (1996) J. Neurosci. , vol.16 , pp. 2553-2562
    • Desagher, S.1    Glowinski, J.2    Premont, J.3
  • 9
    • 0038060334 scopus 로고    scopus 로고
    • Ischemic tolerance and endogenous neuroprotection
    • Dirnagl U., Simon R.P., Hallenbeck J.M. Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 2003, 26:248-254.
    • (2003) Trends Neurosci. , vol.26 , pp. 248-254
    • Dirnagl, U.1    Simon, R.P.2    Hallenbeck, J.M.3
  • 10
    • 58149505960 scopus 로고    scopus 로고
    • Differential insult-dependent recruitment of the intrinsic mitochondrial pathway during neuronal programmed cell death
    • Diwakarla S., Nagley P., Hughes M.L., Chen B., Beart P.M. Differential insult-dependent recruitment of the intrinsic mitochondrial pathway during neuronal programmed cell death. Cell. Mol. Life Sci. 2009, 66:156-172.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 156-172
    • Diwakarla, S.1    Nagley, P.2    Hughes, M.L.3    Chen, B.4    Beart, P.M.5
  • 11
    • 0030852097 scopus 로고    scopus 로고
    • Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells
    • Dringen R., Hamprecht B. Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells. Brain Res. 1997, 759:67-75.
    • (1997) Brain Res. , vol.759 , pp. 67-75
    • Dringen, R.1    Hamprecht, B.2
  • 13
    • 0030772178 scopus 로고    scopus 로고
    • Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency
    • Drukarch B., Schepens E., Jongenelen C.A., Stoof J.C., Langeveld C.H. Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency. Brain Res. 1997, 770:123-130.
    • (1997) Brain Res. , vol.770 , pp. 123-130
    • Drukarch, B.1    Schepens, E.2    Jongenelen, C.A.3    Stoof, J.C.4    Langeveld, C.H.5
  • 14
    • 33745763116 scopus 로고    scopus 로고
    • Cerebral preconditioning and ischaemic tolerance
    • Gidday J.M. Cerebral preconditioning and ischaemic tolerance. Nat. Rev. Neurosci. 2006, 7:437-448.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 437-448
    • Gidday, J.M.1
  • 17
    • 0036328365 scopus 로고    scopus 로고
    • Oligodendroglial cells in culture effectively dispose of exogenous hydrogen peroxide: comparison with cultured neurones, astroglial and microglial cells
    • Hirrlinger J., Resch A., Gutterer J.M., Dringen R. Oligodendroglial cells in culture effectively dispose of exogenous hydrogen peroxide: comparison with cultured neurones, astroglial and microglial cells. J. Neurochem. 2002, 82:635-644.
    • (2002) J. Neurochem. , vol.82 , pp. 635-644
    • Hirrlinger, J.1    Resch, A.2    Gutterer, J.M.3    Dringen, R.4
  • 18
    • 0029310661 scopus 로고
    • Hypoxia-induced vascular endothelial growth factor expression in normal rat astrocyte cultures
    • Ijichi A., Sakuma S., Tofilon P.J. Hypoxia-induced vascular endothelial growth factor expression in normal rat astrocyte cultures. Glia 1995, 14:87-93.
    • (1995) Glia , vol.14 , pp. 87-93
    • Ijichi, A.1    Sakuma, S.2    Tofilon, P.J.3
  • 19
    • 45849134574 scopus 로고    scopus 로고
    • Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride and desferrioxamine against hypoxic-ischemic injury in neonatal rats
    • Jones N.M., Kardashyan L., Callaway J.K., Lee E.M., Beart P.M. Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride and desferrioxamine against hypoxic-ischemic injury in neonatal rats. Pediatr. Res. 2008, 63:620-624.
    • (2008) Pediatr. Res. , vol.63 , pp. 620-624
    • Jones, N.M.1    Kardashyan, L.2    Callaway, J.K.3    Lee, E.M.4    Beart, P.M.5
  • 20
    • 33846990665 scopus 로고    scopus 로고
    • A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent
    • Kim H.L., Yeo E.J., Chun Y.S., Park J.W. A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent. Int. J. Oncol. 2006, 29:255-260.
    • (2006) Int. J. Oncol. , vol.29 , pp. 255-260
    • Kim, H.L.1    Yeo, E.J.2    Chun, Y.S.3    Park, J.W.4
  • 21
    • 0028109332 scopus 로고
    • YC-1, a novel activator of platelet guanylate cyclase
    • Ko F.N., Wu C.C., Kuo S.C., Lee F.Y., Teng C.M. YC-1, a novel activator of platelet guanylate cyclase. Blood 1994, 84:4226-4233.
    • (1994) Blood , vol.84 , pp. 4226-4233
    • Ko, F.N.1    Wu, C.C.2    Kuo, S.C.3    Lee, F.Y.4    Teng, C.M.5
  • 22
    • 0035052469 scopus 로고    scopus 로고
    • Enhanced neuronal protection from oxidative stress by coculture with glutamic acid decarboxylase-expressing astrocytes
    • Lamigeon C., Bellier J.P., Sacchettoni S., Rujano M., Jacquemont B. Enhanced neuronal protection from oxidative stress by coculture with glutamic acid decarboxylase-expressing astrocytes. J. Neurochem. 2001, 77:598-606.
    • (2001) J. Neurochem. , vol.77 , pp. 598-606
    • Lamigeon, C.1    Bellier, J.P.2    Sacchettoni, S.3    Rujano, M.4    Jacquemont, B.5
  • 23
    • 2942627809 scopus 로고    scopus 로고
    • Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide
    • Liddell J.R., Robinson S.R., Dringen R. Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide. Neurosci. Lett. 2004, 364:164-167.
    • (2004) Neurosci. Lett. , vol.364 , pp. 164-167
    • Liddell, J.R.1    Robinson, S.R.2    Dringen, R.3
  • 24
    • 33751237994 scopus 로고    scopus 로고
    • Mechanisms of disease: astrocytes in neurodegenerative disease
    • Maragakis N.J., Rothstein J.D. Mechanisms of disease: astrocytes in neurodegenerative disease. Nat. Clin. Pract. Neurol. 2006, 2:679-689.
    • (2006) Nat. Clin. Pract. Neurol. , vol.2 , pp. 679-689
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 25
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy K.D., de Vellis J. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 1980, 85:890-902.
    • (1980) J. Cell Biol. , vol.85 , pp. 890-902
    • McCarthy, K.D.1    de Vellis, J.2
  • 26
    • 0036669872 scopus 로고    scopus 로고
    • Astrocyte mGlu(2/3)-mediated cAMP potentiation is calcium sensitive: studies in murine neuronal and astrocyte cultures
    • Moldrich R.X., Aprico K., Diwakarla S., O'Shea R.D., Beart P.M. Astrocyte mGlu(2/3)-mediated cAMP potentiation is calcium sensitive: studies in murine neuronal and astrocyte cultures. Neuropharmacology 2002, 43:189-203.
    • (2002) Neuropharmacology , vol.43 , pp. 189-203
    • Moldrich, R.X.1    Aprico, K.2    Diwakarla, S.3    O'Shea, R.D.4    Beart, P.M.5
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 28
    • 24744444711 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha and erythropoietin upregulation with deferoxamine salvage after neonatal stroke
    • Mu D., Chang Y.S., Vexler Z.S., Ferriero D.M. Hypoxia-inducible factor 1alpha and erythropoietin upregulation with deferoxamine salvage after neonatal stroke. Exp. Neurol. 2005, 195:407-415.
    • (2005) Exp. Neurol. , vol.195 , pp. 407-415
    • Mu, D.1    Chang, Y.S.2    Vexler, Z.S.3    Ferriero, D.M.4
  • 29
    • 0032966429 scopus 로고    scopus 로고
    • Differential sensitivity of cultured tanycytes and astrocytes to hydrogen peroxide toxicity
    • Prieto M., Alonso G. Differential sensitivity of cultured tanycytes and astrocytes to hydrogen peroxide toxicity. Exp. Neurol. 1999, 155:118-127.
    • (1999) Exp. Neurol. , vol.155 , pp. 118-127
    • Prieto, M.1    Alonso, G.2
  • 30
    • 0037491813 scopus 로고    scopus 로고
    • Diazoxide pretreatment induces delayed preconditioning in astrocytes against oxygen glucose deprivation and hydrogen peroxide-induced toxicity
    • Rajapakse N., Kis B., Horiguchi T., Snipes J., Busija D. Diazoxide pretreatment induces delayed preconditioning in astrocytes against oxygen glucose deprivation and hydrogen peroxide-induced toxicity. J. Neurosci. Res. 2003, 73:206-214.
    • (2003) J. Neurosci. Res. , vol.73 , pp. 206-214
    • Rajapakse, N.1    Kis, B.2    Horiguchi, T.3    Snipes, J.4    Busija, D.5
  • 32
    • 2342667384 scopus 로고    scopus 로고
    • New roles for VEGF in nervous tissue-beyond blood vessels
    • Rosenstein J.M., Krum J.M. New roles for VEGF in nervous tissue-beyond blood vessels. Exp. Neurol. 2004, 187:246-253.
    • (2004) Exp. Neurol. , vol.187 , pp. 246-253
    • Rosenstein, J.M.1    Krum, J.M.2
  • 33
    • 0023645138 scopus 로고
    • Reduction of collagen production in keloid fibroblast cultures by ethyl-3,4-dihydroxybenzoate. Inhibition of prolyl hydroxylase activity as a mechanism of action
    • Sasaki T., Majamaa K., Uitto J. Reduction of collagen production in keloid fibroblast cultures by ethyl-3,4-dihydroxybenzoate. Inhibition of prolyl hydroxylase activity as a mechanism of action. J. Biol. Chem. 1987, 262:9397-9403.
    • (1987) J. Biol. Chem. , vol.262 , pp. 9397-9403
    • Sasaki, T.1    Majamaa, K.2    Uitto, J.3
  • 34
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
    • Semenza G.L. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol. Med. 2001, 7:345-350.
    • (2001) Trends Mol. Med. , vol.7 , pp. 345-350
    • Semenza, G.L.1
  • 35
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza G.L., Roth P.H., Fang H.M., Wang G.L. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem. 1994, 269:23757-23763.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3    Wang, G.L.4
  • 36
    • 2642555563 scopus 로고    scopus 로고
    • HIF1 and oxygen sensing in the brain
    • Sharp F.R., Bernaudin M. HIF1 and oxygen sensing in the brain. Nat. Rev. Neurosci. 2004, 5:437-448.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 437-448
    • Sharp, F.R.1    Bernaudin, M.2
  • 38
    • 0032561735 scopus 로고    scopus 로고
    • Hypoxic induction of vascular endothelial growth factor (VEGF) protein in astroglial cultures
    • Sinor A.D., Irvin S.M., Cobbs C.S., Chen J., Graham S.H., Greenberg D.A. Hypoxic induction of vascular endothelial growth factor (VEGF) protein in astroglial cultures. Brain Res. 1998, 812:289-291.
    • (1998) Brain Res. , vol.812 , pp. 289-291
    • Sinor, A.D.1    Irvin, S.M.2    Cobbs, C.S.3    Chen, J.4    Graham, S.H.5    Greenberg, D.A.6
  • 39
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum E., Lambrechts D., Carmeliet P. VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 2004, 26:943-954.
    • (2004) Bioessays , vol.26 , pp. 943-954
    • Storkebaum, E.1    Lambrechts, D.2    Carmeliet, P.3
  • 40
    • 20344394152 scopus 로고    scopus 로고
    • Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning
    • Trendelenburg G., Dirnagl U. Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning. Glia 2005, 50:307-320.
    • (2005) Glia , vol.50 , pp. 307-320
    • Trendelenburg, G.1    Dirnagl, U.2
  • 41
    • 39749188133 scopus 로고    scopus 로고
    • The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes
    • Vangeison G., Carr D., Federoff H.J., Rempe D.A. The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes. J. Neurosci. 2008, 28:1988-1993.
    • (2008) J. Neurosci. , vol.28 , pp. 1988-1993
    • Vangeison, G.1    Carr, D.2    Federoff, H.J.3    Rempe, D.A.4
  • 42
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang G.L., Semenza G.L. Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem. 1995, 270:1230-1237.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 43
    • 0037048648 scopus 로고    scopus 로고
    • The prolyl 4-hydroxylase inhibitor ethyl-3, 4-dihydroxybenzoate generates effective iron deficiency in cultured cells
    • Wang J., Buss J.L., Chen G., Ponka P., Pantopoulos K. The prolyl 4-hydroxylase inhibitor ethyl-3, 4-dihydroxybenzoate generates effective iron deficiency in cultured cells. FEBS Lett. 2002, 529:309-312.
    • (2002) FEBS Lett. , vol.529 , pp. 309-312
    • Wang, J.1    Buss, J.L.2    Chen, G.3    Ponka, P.4    Pantopoulos, K.5
  • 44
    • 9444283176 scopus 로고    scopus 로고
    • Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells
    • Warnecke C., Zaborowska Z., Kurreck J., Erdmann V.A., Frei U., Wiesener M., Eckardt K.U. Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J. 2004, 18:1462-1464.
    • (2004) FASEB J. , vol.18 , pp. 1462-1464
    • Warnecke, C.1    Zaborowska, Z.2    Kurreck, J.3    Erdmann, V.A.4    Frei, U.5    Wiesener, M.6    Eckardt, K.U.7
  • 45
    • 33645105323 scopus 로고    scopus 로고
    • Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway
    • Woo K.J., Lee T.J., Park J.W., Kwon T.K. Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway. Biochem. Biophys. Res. Commun. 2006, 343:8-14.
    • (2006) Biochem. Biophys. Res. Commun. , vol.343 , pp. 8-14
    • Woo, K.J.1    Lee, T.J.2    Park, J.W.3    Kwon, T.K.4
  • 46
    • 0038165466 scopus 로고    scopus 로고
    • Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes
    • Wright G., Higgin J.J., Raines R.T., Steenbergen C., Murphy E. Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes. J. Biol. Chem. 2003, 278:20235-20239.
    • (2003) J. Biol. Chem. , vol.278 , pp. 20235-20239
    • Wright, G.1    Higgin, J.J.2    Raines, R.T.3    Steenbergen, C.4    Murphy, E.5
  • 47
    • 1942440384 scopus 로고    scopus 로고
    • Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1
    • Yang D.I., Chen S.D., Yang Y.T., Ju T.C., Xu J.M., Hsu C.Y. Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1. Br. J. Pharmacol. 2004, 141:988-996.
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 988-996
    • Yang, D.I.1    Chen, S.D.2    Yang, Y.T.3    Ju, T.C.4    Xu, J.M.5    Hsu, C.Y.6
  • 48
    • 18144374584 scopus 로고    scopus 로고
    • Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells
    • Yang Y.T., Ju T.C., Yang D.I. Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells. J. Neurochem. 2005, 93:513-525.
    • (2005) J. Neurochem. , vol.93 , pp. 513-525
    • Yang, Y.T.1    Ju, T.C.2    Yang, D.I.3
  • 49
    • 0035859692 scopus 로고    scopus 로고
    • HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation
    • Yu F., White S.B., Zhao Q., Lee F.S. HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:9630-9635.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 9630-9635
    • Yu, F.1    White, S.B.2    Zhao, Q.3    Lee, F.S.4
  • 50
    • 0033571939 scopus 로고    scopus 로고
    • Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin
    • Zaman K., Ryu H., Hall D., O'Donovan K., Lin K.I., Miller M.P., Marquis J.C., Baraban J.M., Semenza G.L., Ratan R.R. Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin. J. Neurosci. 1999, 19:9821-9830.
    • (1999) J. Neurosci. , vol.19 , pp. 9821-9830
    • Zaman, K.1    Ryu, H.2    Hall, D.3    O'Donovan, K.4    Lin, K.I.5    Miller, M.P.6    Marquis, J.C.7    Baraban, J.M.8    Semenza, G.L.9    Ratan, R.R.10


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