Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor

Journal of Neuroscience Research

Volumn 88, Issue 8, 2010, Pages 1664-1672

  Yu, Jie Zhong ^a,b   Ding, Jing ^c   Ma, Cun Gen ^b   Sun, Chang Hai ^d   Sun, Yi Fu ^d   Lu, Chuan Zhen ^a   Xiao, Bao Guo ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANXI DATONG UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d Tianjin Chase Sun Pharmaceutical Co Ltd   (China)

Author keywords

Experimental autoimmune encephalomyelitis; Fasudil; Multiple sclerosis; Rho kinase inhibitor

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CELL PROTEIN; FASUDIL; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PROTEIN ROCK II; UNCLASSIFIED DRUG; VASCULOTROPIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EXPERIMENTAL STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; MONONUCLEAR CELL; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SPINAL CORD; SPLEEN; STAINING; T LYMPHOCYTE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANALYSIS OF VARIANCE; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOPROTEINS; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; SEVERITY OF ILLNESS INDEX; SPINAL CORD; SPLEEN;

EID: 77952357821     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22339     Document Type: Article

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