메뉴 건너뛰기




Volumn 9, Issue FEB, 2015, Pages

Cerebral metabolism following traumatic brain injury: New discoveries with implications for treatment

Author keywords

Brain fuel; Brain metabolism; Gluconeogenesis; Lactate shuttle; Trauma

Indexed keywords

GLUCOSE; INSULIN; LACTIC ACID; OXYGEN;

EID: 84924345565     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2014.00408     Document Type: Article
Times cited : (52)

References (111)
  • 1
    • 0020084448 scopus 로고
    • Lactate and glucose exchange across the forearm, legs, and splanchnic bed during and after prolonged leg exercise
    • Ahlborg, G., and Felig, P. (1982). Lactate and glucose exchange across the forearm, legs, and splanchnic bed during and after prolonged leg exercise. J. Clin. Invest. 69, 45-54. doi: 10.1172/JCI110440
    • (1982) J. Clin. Invest. , vol.69 , pp. 45-54
    • Ahlborg, G.1    Felig, P.2
  • 2
    • 84865208378 scopus 로고    scopus 로고
    • The neuroprotective effect of lactate is not due to improved glutamate uptake after controlled cortical impact in rats
    • Alessandri, B., Schwandt, E., Kamada, Y., Nagata, M., Heimann, A., and Kempski, O. (2012). The neuroprotective effect of lactate is not due to improved glutamate uptake after controlled cortical impact in rats. J. Neurotrauma 29, 2181-2191. doi: 10.1089/neu.2011.2067
    • (2012) J. Neurotrauma , vol.29 , pp. 2181-2191
    • Alessandri, B.1    Schwandt, E.2    Kamada, Y.3    Nagata, M.4    Heimann, A.5    Kempski, O.6
  • 3
    • 27444445186 scopus 로고    scopus 로고
    • Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury
    • Bartnik, B. L., Sutton, R. L., Fukushima, M., Harris, N. G., Hovda, D. A., and Lee, S. M. (2005). Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury. J. Neurotrauma 22, 1052-1065. doi: 10.1089/neu.2005.22.1052
    • (2005) J. Neurotrauma , vol.22 , pp. 1052-1065
    • Bartnik, B.L.1    Sutton, R.L.2    Fukushima, M.3    Harris, N.G.4    Hovda, D.A.5    Lee, S.M.6
  • 5
    • 65449180332 scopus 로고    scopus 로고
    • Myocardial glucose and lactate metabolism during rest and atrial pacing in humans
    • Bergman, B. C., Tsvetkova, T., Lowes, B., and Wolfel, E. E. (2009). Myocardial glucose and lactate metabolism during rest and atrial pacing in humans. J. Physiol. 587(Pt 9): 2087-2099. doi: 10.1113/jphysiol.2008.168286
    • (2009) J. Physiol , vol.587 , pp. 2087-2099
    • Bergman, B.C.1    Tsvetkova, T.2    Lowes, B.3    Wolfel, E.E.4
  • 7
    • 0030997119 scopus 로고    scopus 로고
    • Cerebral hyperglycolysis following severe traumatic brain injury in humans: a positron emission tomography study
    • Bergsneider, M., Hovda, D. A., Shalmon, E., Kelly, D. F., Vespa, P. M., Martin, N. A., et al. (1997). Cerebral hyperglycolysis following severe traumatic brain injury in humans: a positron emission tomography study. J. Neurosurg. 86, 241-251. doi: 10.3171/jns.1997.86.2.0241
    • (1997) J. Neurosurg. , vol.86 , pp. 241-251
    • Bergsneider, M.1    Hovda, D.A.2    Shalmon, E.3    Kelly, D.F.4    Vespa, P.M.5    Martin, N.A.6
  • 8
    • 84899412718 scopus 로고    scopus 로고
    • Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain
    • Bouzat, P., Sala, N., Suys, T., Zerlauth, J. B., Marques-Vidal, P., Feihl, F., et al. (2014). Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain. Intensive Care Med. 40, 412-421. doi: 10.1007/s00134-013-3203-6
    • (2014) Intensive Care Med. , vol.40 , pp. 412-421
    • Bouzat, P.1    Sala, N.2    Suys, T.3    Zerlauth, J.B.4    Marques-Vidal, P.5    Feihl, F.6
  • 9
    • 84863552418 scopus 로고    scopus 로고
    • A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans
    • Bricker, D. K., Taylor, E. B., Schell, J. C., Orsak, T., Boutron, A., Chen, Y. C., et al. (2012). A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science 337, 96-100. doi: 10.1126/science.1218099
    • (2012) Science , vol.337 , pp. 96-100
    • Bricker, D.K.1    Taylor, E.B.2    Schell, J.C.3    Orsak, T.4    Boutron, A.5    Chen, Y.C.6
  • 10
    • 0002668328 scopus 로고
    • Lactate: glycolytic end product and oxidative substrate during sustained exercise in mammals-the lactate shuttle
    • Respiration - Metabolism - Circulation, ed R. Gilles (Berlin: Springer Verlag)
    • Brooks, G. A. (1984). "Lactate: glycolytic end product and oxidative substrate during sustained exercise in mammals-the lactate shuttle," in Comparative Physiology and Biochemistry - Current Topics and Trends, Vol. A, Respiration - Metabolism - Circulation, ed R. Gilles (Berlin: Springer Verlag), 208-218.
    • (1984) Comparative Physiology and Biochemistry - Current Topics and Trends , vol.A , pp. 208-218
    • Brooks, G.A.1
  • 11
    • 71249103087 scopus 로고    scopus 로고
    • Cell-cell and intracellular lactate shuttles
    • Brooks, G. A. (2009). Cell-cell and intracellular lactate shuttles. J. Physiol. 587(Pt 23): 5591-5600. doi: 10.1113/jphysiol.2009.178350
    • (2009) J. Physiol , vol.587 , pp. 5591-5600
    • Brooks, G.A.1
  • 13
    • 0020580077 scopus 로고
    • Effect of endurance training on glucose kinetics during exercise
    • Brooks, G. A., and Donovan, C. M. (1983). Effect of endurance training on glucose kinetics during exercise. Am. J. Physiol. 244, E505-E512.
    • (1983) Am. J. Physiol. , vol.244 , pp. E505-E512
    • Brooks, G.A.1    Donovan, C.M.2
  • 14
    • 0033514475 scopus 로고    scopus 로고
    • Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle
    • Brooks, G. A., Dubouchaud, H., Brown, M., Sicurello, J. P., and Butz, C. E. (1999b). Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle. Proc. Natl. Acad. Sci. U.S.A. 96, 1129-1134. doi: 10.1073/pnas.96.3.1129
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 1129-1134
    • Brooks, G.A.1    Dubouchaud, H.2    Brown, M.3    Sicurello, J.P.4    Butz, C.E.5
  • 15
    • 0031768125 scopus 로고    scopus 로고
    • Poor relationship between arterial [lactate] and leg net release during exercise at 4,300 m altitude
    • Brooks, G. A., Wolfel, E. E., Butterfield, G. E., Cymerman, A., Roberts, A. C., Mazzeo, R. S., et al. (1998). Poor relationship between arterial [lactate] and leg net release during exercise at 4,300 m altitude. Am. J. Physiol. 275(4 Pt 2): R1192-R1201.
    • (1998) Am. J. Physiol , vol.275 , Issue.4 , pp. R1192-R1201
    • Brooks, G.A.1    Wolfel, E.E.2    Butterfield, G.E.3    Cymerman, A.4    Roberts, A.C.5    Mazzeo, R.S.6
  • 16
    • 0014378427 scopus 로고
    • The consumption of fuels during prolonged starvation
    • Cahill, G. J. Jr., Owen, O. E., and Morgan, A. P. (1968). The consumption of fuels during prolonged starvation. Adv. Enzyme Regul. 6, 143-150. doi: 10.1016/0065-2571(68)90011-3
    • (1968) Adv. Enzyme Regul. , vol.6 , pp. 143-150
    • Cahill, G.J.1    Owen, O.E.2    Morgan, A.P.3
  • 17
    • 78751647183 scopus 로고    scopus 로고
    • Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a randomized controlled trial
    • Casaer, M. P., Hermans, G., Wilmer, A., and Van den Berghe, G. (2011a). Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a randomized controlled trial. Trials 12, 21. doi: 10.1186/1745-6215-12-21
    • (2011) Trials , vol.12 , pp. 21
    • Casaer, M.P.1    Hermans, G.2    Wilmer, A.3    Van den Berghe, G.4
  • 19
    • 0035577699 scopus 로고    scopus 로고
    • Glucose and lactate metabolism during brain activation
    • Dienel, G. A., and Hertz, L. (2001). Glucose and lactate metabolism during brain activation. J. Neurosci. Res. 66, 824-838. doi: 10.1002/jnr.10079
    • (2001) J. Neurosci. Res. , vol.66 , pp. 824-838
    • Dienel, G.A.1    Hertz, L.2
  • 21
    • 0020674143 scopus 로고
    • Endurance training affects lactate clearance, not lactate production
    • Donovan, C. M., and Brooks, G. A. (1983). Endurance training affects lactate clearance, not lactate production. Am. J. Physiol. 244, E83-E92.
    • (1983) Am. J. Physiol. , vol.244 , pp. E83-E92
    • Donovan, C.M.1    Brooks, G.A.2
  • 22
    • 0034001224 scopus 로고    scopus 로고
    • Endurance training, expression, and physiology of LDH, MCT1, and MCT4 in human skeletal muscle
    • Dubouchaud, H., Butterfield, G. E., Wolfel, E. E., Bergman, B. C., and Brooks, G. A. (2000). Endurance training, expression, and physiology of LDH, MCT1, and MCT4 in human skeletal muscle. Am. J. Physiol. 278, E571-E579.
    • (2000) Am. J. Physiol. , vol.278 , pp. E571-E579
    • Dubouchaud, H.1    Butterfield, G.E.2    Wolfel, E.E.3    Bergman, B.C.4    Brooks, G.A.5
  • 23
    • 34548125766 scopus 로고    scopus 로고
    • Increased pentose phosphate pathway flux after clinical traumatic brain injury: a [1,2-13C2]glucose labeling study in humans
    • Dusick, J. R., Glenn, T. C., Lee, W. N., Vespa, P. M., Kelly, D. F., Lee, S. M., et al. (2007). Increased pentose phosphate pathway flux after clinical traumatic brain injury: a [1,2-13C2]glucose labeling study in humans. J. Cereb. Blood Flow Metab. 27, 1593-1602. doi: 10.1038/sj.jcbfm.9600458
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 1593-1602
    • Dusick, J.R.1    Glenn, T.C.2    Lee, W.N.3    Vespa, P.M.4    Kelly, D.F.5    Lee, S.M.6
  • 25
    • 0021692099 scopus 로고
    • Banting lecture 1984. From glycogen to ketones-and back
    • Foster, D. W. (1984). Banting lecture 1984. From glycogen to ketones-and back. Diabetes 33, 1188-1199. doi: 10.2337/diab.33.12.1188
    • (1984) Diabetes , vol.33 , pp. 1188-1199
    • Foster, D.W.1
  • 26
    • 70349957926 scopus 로고    scopus 로고
    • The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study
    • Gallagher, C. N., Carpenter, K. L., Grice, P., Howe, D. J., Mason, A., Timofeev, I., et al. (2009). The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study. Brain 132(Pt 10): 2839-2849. doi: 10.1093/brain/awp202
    • (2009) Brain , vol.132 , pp. 2839-2849
    • Gallagher, C.N.1    Carpenter, K.L.2    Grice, P.3    Howe, D.J.4    Mason, A.5    Timofeev, I.6
  • 27
    • 0028909335 scopus 로고
    • cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1
    • Garcia, C. K., Brown, M. S., Pathak, R. K., and Goldstein, J. L. (1995). cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1. J. Biol. Chem. 270, 1843-1849. doi: 10.1074/jbc.270.4.1843
    • (1995) J. Biol. Chem. , vol.270 , pp. 1843-1849
    • Garcia, C.K.1    Brown, M.S.2    Pathak, R.K.3    Goldstein, J.L.4
  • 28
    • 0028294023 scopus 로고
    • Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle
    • Garcia, C. K., Goldstein, J. L., Pathak, R. K., Anderson, R. G., and Brown, M. S. (1994). Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Cell 76, 865-873. doi: 10.1016/0092-8674(94)90361-1
    • (1994) Cell , vol.76 , pp. 865-873
    • Garcia, C.K.1    Goldstein, J.L.2    Pathak, R.K.3    Anderson, R.G.4    Brown, M.S.5
  • 29
    • 0019434531 scopus 로고
    • Myocardial lactate metabolism: evidence of lactate release during net chemical extraction in man
    • Gertz, E. W., Wisneski, J. A., Neese, R., Bristow, J. D., Searle, G. L., and Hanlon, J. T. (1981). Myocardial lactate metabolism: evidence of lactate release during net chemical extraction in man. Circulation 63, 1273-1279. doi: 10.1161/01.CIR.63.6.1273
    • (1981) Circulation , vol.63 , pp. 1273-1279
    • Gertz, E.W.1    Wisneski, J.A.2    Neese, R.3    Bristow, J.D.4    Searle, G.L.5    Hanlon, J.T.6
  • 30
    • 0024267688 scopus 로고
    • Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments
    • Gertz, E. W., Wisneski, J. A., Stanley, W. C., and Neese, R. A. (1988). Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments. J. Clin. Invest. 82, 2017-2025. doi: 10.1172/JCI113822
    • (1988) J. Clin. Invest. , vol.82 , pp. 2017-2025
    • Gertz, E.W.1    Wisneski, J.A.2    Stanley, W.C.3    Neese, R.A.4
  • 31
    • 0141891196 scopus 로고    scopus 로고
    • Energy dysfunction as a predictor of outcome after moderate or severe head injury: indices of oxygen, glucose, and lactate metabolism
    • Glenn, T. C., Kelly, D. F., Boscardin, W. J., McArthur, D. L., Vespa, P., Oertel, M., et al. (2003). Energy dysfunction as a predictor of outcome after moderate or severe head injury: indices of oxygen, glucose, and lactate metabolism. J. Cereb. Blood Flow Metab. 23, 1239-1250. doi: 10.1097/01.WCB.0000089833.23606.7F
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 1239-1250
    • Glenn, T.C.1    Kelly, D.F.2    Boscardin, W.J.3    McArthur, D.L.4    Vespa, P.5    Oertel, M.6
  • 33
    • 84930335880 scopus 로고    scopus 로고
    • Endogenous nutritive support following traumatic brain injury: peripheral lactate production for glucose supply via gluconeogenesis
    • [Epub ahead of print].
    • Glenn, T. C., Martin, N. A., Mcarthur, D. L., Hovda, D., Vespa, P. M. M., Horning, M. A., et al. (2014). Endogenous nutritive support following traumatic brain injury: peripheral lactate production for glucose supply via gluconeogenesis. J. Neurotrauma. doi: 10.1089/neu.2014.3482. [Epub ahead of print].
    • (2014) J. Neurotrauma
    • Glenn, T.C.1    Martin, N.A.2    Mcarthur, D.L.3    Hovda, D.4    Vespa, P.M.M.5    Horning, M.A.6
  • 34
    • 41949087141 scopus 로고    scopus 로고
    • Too much of a good thing: the curse of overfeeding
    • Griffiths, R. D. (2007). Too much of a good thing: the curse of overfeeding. Crit. Care 11, 176. doi: 10.1186/cc6165
    • (2007) Crit. Care , vol.11 , pp. 176
    • Griffiths, R.D.1
  • 35
    • 58849157916 scopus 로고    scopus 로고
    • Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z, E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice
    • Guo, J., Parise, R. A., Joseph, E., Egorin, M. J., Lazo, J. S., Prochownik, E. V., et al. (2009). Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z, E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice. Cancer Chemother. Pharmacol. 63, 615-625. doi: 10.1007/s00280-008-0774-y
    • (2009) Cancer Chemother. Pharmacol. , vol.63 , pp. 615-625
    • Guo, J.1    Parise, R.A.2    Joseph, E.3    Egorin, M.J.4    Lazo, J.S.5    Prochownik, E.V.6
  • 36
    • 27044432604 scopus 로고
    • A biometric study of human basal metabolism
    • Harris, J. A., and Benedict, F. G. (1918). A biometric study of human basal metabolism. Proc. Natl. Acad. Sci. U.S.A. 4, 370-373. doi: 10.1073/pnas.4.12.370
    • (1918) Proc. Natl. Acad. Sci. U.S.A. , vol.4 , pp. 370-373
    • Harris, J.A.1    Benedict, F.G.2
  • 37
    • 33744931101 scopus 로고    scopus 로고
    • Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex
    • Hashimoto, T., Hussien, R., and Brooks, G. A. (2006). Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex. Am. J. Physiol. 290, E1237-E1244. doi: 10.1152/ajpendo.00594.2005
    • (2006) Am. J. Physiol. , vol.290 , pp. E1237-E1244
    • Hashimoto, T.1    Hussien, R.2    Brooks, G.A.3
  • 38
    • 51449120723 scopus 로고    scopus 로고
    • Evidence for the mitochondrial lactate oxidation complex in rat neurons: demonstration of an essential component of brain lactate shuttles
    • Hashimoto, T., Hussien, R., Cho, H. S., Kaufer, D., and Brooks, G. A. (2008). Evidence for the mitochondrial lactate oxidation complex in rat neurons: demonstration of an essential component of brain lactate shuttles. PLoS ONE 3:e2915. doi: 10.1371/journal.pone.0002915
    • (2008) PLoS ONE , vol.3
    • Hashimoto, T.1    Hussien, R.2    Cho, H.S.3    Kaufer, D.4    Brooks, G.A.5
  • 40
    • 70350070509 scopus 로고    scopus 로고
    • Differences in outcome between the NICE-SUGAR and Leuven trials: possible methodological explanations
    • Henderson, W. R., and Finfer, S. (2009). Differences in outcome between the NICE-SUGAR and Leuven trials: possible methodological explanations. Crit. Care Resusc. 11, 175-177.
    • (2009) Crit. Care Resusc. , vol.11 , pp. 175-177
    • Henderson, W.R.1    Finfer, S.2
  • 41
    • 84863553135 scopus 로고    scopus 로고
    • Identification and functional expression of the mitochondrial pyruvate carrier
    • Herzig, S., Raemy, E., Montessuit, S., Veuthey, J. L., Zamboni, N., Westermann, B., et al. (2012). Identification and functional expression of the mitochondrial pyruvate carrier. Science 337, 93-96. doi: 10.1126/science.1218530
    • (2012) Science , vol.337 , pp. 93-96
    • Herzig, S.1    Raemy, E.2    Montessuit, S.3    Veuthey, J.L.4    Zamboni, N.5    Westermann, B.6
  • 42
    • 84877144584 scopus 로고    scopus 로고
    • Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia
    • Herzog, R. I., Jiang, L., Herman, P., Zhao, C., Sanganahalli, B. G., Mason, G. F., et al. (2013). Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia. J. Clin. Invest. 123, 1988-1998. doi: 10.1172/JCI65105
    • (2013) J. Clin. Invest. , vol.123 , pp. 1988-1998
    • Herzog, R.I.1    Jiang, L.2    Herman, P.3    Zhao, C.4    Sanganahalli, B.G.5    Mason, G.F.6
  • 43
    • 0032376126 scopus 로고    scopus 로고
    • Violin plots: a box plot-density trace synergism
    • Hintze, J. L., and Nelson, R. D. (1998). Violin plots: a box plot-density trace synergism. Am. Stat. 52, 181-184.
    • (1998) Am. Stat. , vol.52 , pp. 181-184
    • Hintze, J.L.1    Nelson, R.D.2
  • 44
    • 34548225552 scopus 로고    scopus 로고
    • Effect of lactate therapy upon cognitive deficits after traumatic brain injury in the rat
    • discussion: 927
    • Holloway, R., Zhou, Z., Harvey, H. B., Levasseur, J. E., Rice, A. C., Sun, D., et al. (2007). Effect of lactate therapy upon cognitive deficits after traumatic brain injury in the rat. Acta Neurochirur. 149, 919-927. discussion: 927. doi: 10.1007/s00701-007-1241-y
    • (2007) Acta Neurochirur. , vol.149 , pp. 919-927
    • Holloway, R.1    Zhou, Z.2    Harvey, H.B.3    Levasseur, J.E.4    Rice, A.C.5    Sun, D.6
  • 46
    • 84924392544 scopus 로고    scopus 로고
    • Systems and Methods to Estimate Nutritional Needs of Human and other Patients
    • US 8'827,490 B2. Alexandria, VA: US Patent and Trade Office
    • Horning, M. A., and Brooks, G. A. (2012b). Systems and Methods to Estimate Nutritional Needs of Human and other Patients. US 8'827,490 B2. Alexandria, VA: US Patent and Trade Office.
    • (2012)
    • Horning, M.A.1    Brooks, G.A.2
  • 47
    • 0002462613 scopus 로고
    • Physiological role of muscle glycogen in man
    • Hultman, E. A. (1967). Physiological role of muscle glycogen in man. Physiol. Muscular Exercise (Suppl. 1), I99-I112.
    • (1967) Physiol. Muscular Exercise , pp. I99-I112
    • Hultman, E.A.1
  • 48
    • 60449118292 scopus 로고    scopus 로고
    • Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients
    • Ichai, C., Armando, G., Orban, J. C., Berthier, F., Rami, L., Samat-Long, C., et al. (2009). Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. Intensive Care Med. 35, 471-479. doi: 10.1007/s00134-008-1283-5
    • (2009) Intensive Care Med. , vol.35 , pp. 471-479
    • Ichai, C.1    Armando, G.2    Orban, J.C.3    Berthier, F.4    Rami, L.5    Samat-Long, C.6
  • 49
    • 84880298733 scopus 로고    scopus 로고
    • Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial
    • Ichai, C., Payen, J. F., Orban, J. C., Quintard, H., Roth, H., Legrand, R., et al. (2013). Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial. Intensive Care Med. 39, 1413-1422. doi: 10.1007/s00134-013-2978-9
    • (2013) Intensive Care Med. , vol.39 , pp. 1413-1422
    • Ichai, C.1    Payen, J.F.2    Orban, J.C.3    Quintard, H.4    Roth, H.5    Legrand, R.6
  • 50
    • 84964134248 scopus 로고
    • Plasma free fatty acids during exercise and the effect of lactic acid
    • Issekutz, B. J., and Miller, H. (1962). Plasma free fatty acids during exercise and the effect of lactic acid. Proc. Soc. Exp. Biol. Med. 110, 237-239.
    • (1962) Proc. Soc. Exp. Biol. Med. , vol.110 , pp. 237-239
    • Issekutz, B.J.1    Miller, H.2
  • 51
    • 84890447871 scopus 로고    scopus 로고
    • Lactate uptake by the injured human brain: evidence from an arteriovenous gradient and cerebral microdialysis study
    • Jalloh, I., Helmy, A., Shannon, R. J., Gallagher, C. N., Menon, D. K., Carpenter, K. L., et al. (2013). Lactate uptake by the injured human brain: evidence from an arteriovenous gradient and cerebral microdialysis study. J. Neurotrauma 30, 2031-2037. doi: 10.1089/neu.2013.2947
    • (2013) J. Neurotrauma , vol.30 , pp. 2031-2037
    • Jalloh, I.1    Helmy, A.2    Shannon, R.J.3    Gallagher, C.N.4    Menon, D.K.5    Carpenter, K.L.6
  • 52
    • 0015451016 scopus 로고
    • The role of the skin in carbohydrate metabolism
    • Johnson, J. A., and Fusaro, R. M. (1972). The role of the skin in carbohydrate metabolism. Adv. Metab. Disord. 60, 1-55. doi: 10.1016/B978-0-12-027306-5.50006-1
    • (1972) Adv. Metab. Disord. , vol.60 , pp. 1-55
    • Johnson, J.A.1    Fusaro, R.M.2
  • 55
    • 0034454498 scopus 로고    scopus 로고
    • Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study
    • Krssak, M., Petersen, K. F., Bergeron, R., Price, T., Laurent, D., Rothman, D. L., et al. (2000). Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study. J. Clin. Endocrinol. Metab. 85, 748-754. doi: 10.1210/jc.85.2.748
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 748-754
    • Krssak, M.1    Petersen, K.F.2    Bergeron, R.3    Price, T.4    Laurent, D.5    Rothman, D.L.6
  • 57
    • 0142243372 scopus 로고    scopus 로고
    • Antioxidant properties of myocardial fuels
    • Mallet, R. T., and Sun, J. (2003). Antioxidant properties of myocardial fuels. Mol. Cell. Biochem. 253, 103-111. doi: 10.1023/A:1026009519783
    • (2003) Mol. Cell. Biochem. , vol.253 , pp. 103-111
    • Mallet, R.T.1    Sun, J.2
  • 58
    • 84881475074 scopus 로고    scopus 로고
    • Glycemic control in critically ill patients: What to do post NICE-SUGAR?
    • Marik, P. E. (2009). Glycemic control in critically ill patients: What to do post NICE-SUGAR? World J. Gastrointest. Surg. 1, 3-5. doi: 10.4240/wjgs.v1.i1.3
    • (2009) World J. Gastrointest. Surg. , vol.1 , pp. 3-5
    • Marik, P.E.1
  • 59
    • 0022508739 scopus 로고
    • Disposal of blood [1-13C]lactate in humans during rest and exercise
    • Mazzeo, R. S., Brooks, G. A., Schoeller, D. A., and Budinger, T. F. (1986). Disposal of blood [1-13C]lactate in humans during rest and exercise. J. Appl. Physiol. 60, 232-241.
    • (1986) J. Appl. Physiol. , vol.60 , pp. 232-241
    • Mazzeo, R.S.1    Brooks, G.A.2    Schoeller, D.A.3    Budinger, T.F.4
  • 62
    • 33748297182 scopus 로고    scopus 로고
    • Towards a feasible algorithm for tight glycaemic control in critically ill patients: a systematic review of the literature
    • Meijering, S., Corstjens, A. M., Tulleken, J. E., Meertens, J. H., Zijlstra, J. G., and Ligtenberg, J. J. (2006). Towards a feasible algorithm for tight glycaemic control in critically ill patients: a systematic review of the literature. Crit. Care 10, R19. doi: 10.1186/cc3981
    • (2006) Crit. Care , vol.10 , pp. R19
    • Meijering, S.1    Corstjens, A.M.2    Tulleken, J.E.3    Meertens, J.H.4    Zijlstra, J.G.5    Ligtenberg, J.J.6
  • 64
    • 0036084280 scopus 로고    scopus 로고
    • Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis
    • Meyer, C., Dostou, J. M., Welle, S. L., and Gerich, J. E. (2002). Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis. Am. J. Physiol. Endocrinol. Metab. 282, E419-E427. doi: 10.1152/ajpendo.00032.2001
    • (2002) Am. J. Physiol. Endocrinol. Metab. , vol.282 , pp. E419-E427
    • Meyer, C.1    Dostou, J.M.2    Welle, S.L.3    Gerich, J.E.4
  • 65
    • 0036850894 scopus 로고    scopus 로고
    • Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion
    • Miller, B. F., Fattor, J. A., Jacobs, K. A., Horning, M. A., Navazio, F., Lindinger, M. I., et al. (2002a). Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion. J. Physiol. 544(Pt 3): 963-975. doi: 10.1113/jphysiol.2002.027128
    • (2002) J. Physiol , vol.544 , pp. 963-975
    • Miller, B.F.1    Fattor, J.A.2    Jacobs, K.A.3    Horning, M.A.4    Navazio, F.5    Lindinger, M.I.6
  • 67
    • 14144255758 scopus 로고    scopus 로고
    • Hematological and acid-base changes in men during prolonged exercise with and without sodium-lactate infusion
    • Miller, B. F., Lindinger, M. I., Fattor, J. A., Jacobs, K. A., Leblanc, P. J., Duong, M., et al. (2005). Hematological and acid-base changes in men during prolonged exercise with and without sodium-lactate infusion. J. Appl. Physiol. 98, 856-865. doi: 10.1152/japplphysiol.00753.2004
    • (2005) J. Appl. Physiol. , vol.98 , pp. 856-865
    • Miller, B.F.1    Lindinger, M.I.2    Fattor, J.A.3    Jacobs, K.A.4    Leblanc, P.J.5    Duong, M.6
  • 68
    • 70350054977 scopus 로고    scopus 로고
    • Differences in outcome between the NICE-SUGAR and Leuven trials: biological mechanisms of intensive glucose control in critically ill patients
    • Myburgh, J. A., and Chittock, D. R. (2009). Differences in outcome between the NICE-SUGAR and Leuven trials: biological mechanisms of intensive glucose control in critically ill patients. Crit. Care Resusc 11, 178-179.
    • (2009) Crit. Care Resusc , vol.11 , pp. 178-179
    • Myburgh, J.A.1    Chittock, D.R.2
  • 70
    • 0016031704 scopus 로고
    • Liver and muscle glycogen in man after glucose and fructose infusion
    • Nilsson, L. H., and Hultman, E. (1974). Liver and muscle glycogen in man after glucose and fructose infusion. Scand. J. Clin. Lab. Invest. 33, 5-10. doi: 10.3109/00365517409114190
    • (1974) Scand. J. Clin. Lab. Invest. , vol.33 , pp. 5-10
    • Nilsson, L.H.1    Hultman, E.2
  • 71
    • 84860219826 scopus 로고    scopus 로고
    • Brain lactate metabolism in humans with subarachnoid hemorrhage
    • Oddo, M., Levine, J. M., Frangos, S., Maloney-Wilensky, E., Carrera, E., Daniel, R. T., et al. (2012). Brain lactate metabolism in humans with subarachnoid hemorrhage. Stroke 43, 1418-1421. doi: 10.1161/STROKEAHA.111.648568
    • (2012) Stroke , vol.43 , pp. 1418-1421
    • Oddo, M.1    Levine, J.M.2    Frangos, S.3    Maloney-Wilensky, E.4    Carrera, E.5    Daniel, R.T.6
  • 72
    • 33947102530 scopus 로고    scopus 로고
    • Human brain glycogen content and metabolism: implications on its role in brain energy metabolism
    • Oz, G., Seaquist, E. R., Kumar, A., Criego, A. B., Benedict, L. E., Rao, J. P., et al. (2007). Human brain glycogen content and metabolism: implications on its role in brain energy metabolism. Am. J. Physiol. Endocrinol. Metab. 292, E946-E951. doi: 10.1152/ajpendo.00424.2006
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.292 , pp. E946-E951
    • Oz, G.1    Seaquist, E.R.2    Kumar, A.3    Criego, A.B.4    Benedict, L.E.5    Rao, J.P.6
  • 73
    • 12244262261 scopus 로고    scopus 로고
    • Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain
    • Pellerin, L., Bergersen, L. H., Halestrap, A. P., and Pierre, K. (2005). Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain. J. Neurosci. Res. 79, 55-64. doi: 10.1002/jnr.20307
    • (2005) J. Neurosci. Res. , vol.79 , pp. 55-64
    • Pellerin, L.1    Bergersen, L.H.2    Halestrap, A.P.3    Pierre, K.4
  • 74
    • 33144486505 scopus 로고    scopus 로고
    • Enteral nutrition delivery and energy expenditure in medical intensive care patients
    • Petros, S., and Engelmann, L. (2006). Enteral nutrition delivery and energy expenditure in medical intensive care patients. Clin. Nutr. 25, 51-59. doi: 10.1016/j.clnu.2005.08.013
    • (2006) Clin. Nutr. , vol.25 , pp. 51-59
    • Petros, S.1    Engelmann, L.2
  • 75
    • 21344444566 scopus 로고    scopus 로고
    • Monocarboxylate transporters in the central nervous system: distribution, regulation and function
    • Pierre, K., and Pellerin, L. (2005). Monocarboxylate transporters in the central nervous system: distribution, regulation and function. J. Neurochem. 94, 1-14. doi: 10.1111/j.1471-4159.2005.03168.x
    • (2005) J. Neurochem. , vol.94 , pp. 1-14
    • Pierre, K.1    Pellerin, L.2
  • 76
    • 84864102577 scopus 로고    scopus 로고
    • Cerebral ketone metabolism during development and injury
    • Prins, M. L. (2012). Cerebral ketone metabolism during development and injury. Epilepsy Res. 100, 218-223. doi: 10.1016/j.eplepsyres.2011.09.027
    • (2012) Epilepsy Res. , vol.100 , pp. 218-223
    • Prins, M.L.1
  • 77
    • 33748186181 scopus 로고    scopus 로고
    • Induction of monocarboxylate transporter 2 expression and ketone transport following traumatic brain injury in juvenile and adult rats
    • Prins, M. L., and Giza, C. C. (2006). Induction of monocarboxylate transporter 2 expression and ketone transport following traumatic brain injury in juvenile and adult rats. Dev. Neurosci. 28, 447-456. doi: 10.1159/000094170
    • (2006) Dev. Neurosci. , vol.28 , pp. 447-456
    • Prins, M.L.1    Giza, C.C.2
  • 78
    • 69249101222 scopus 로고    scopus 로고
    • The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats
    • Prins, M. L., and Hovda, D. A. (2009). The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats. J. Neurotrauma 26, 1083-1093. doi: 10.1089/neu.2008.0769
    • (2009) J. Neurotrauma , vol.26 , pp. 1083-1093
    • Prins, M.L.1    Hovda, D.A.2
  • 79
    • 0037154801 scopus 로고    scopus 로고
    • Lactate administration attenuates cognitive deficits following traumatic brain injury
    • Rice, A. C., Zsoldos, R., Chen, T., Wilson, M. S., Alessandri, B., Hamm, R. J., et al. (2002). Lactate administration attenuates cognitive deficits following traumatic brain injury. Brain Res. 928, 156-159. doi: 10.1016/S0006-8993(01)03299-1
    • (2002) Brain Res. , vol.928 , pp. 156-159
    • Rice, A.C.1    Zsoldos, R.2    Chen, T.3    Wilson, M.S.4    Alessandri, B.5    Hamm, R.J.6
  • 80
    • 0031880556 scopus 로고    scopus 로고
    • Lactate efflux from exercising human skeletal muscle: role of intracellular PO2
    • Richardson, R. S., Noyszewski, E. A., Leigh, J. S., and Wagner, P. D. (1998). Lactate efflux from exercising human skeletal muscle: role of intracellular PO2. J. Appl. Physiol. 85, 627-634.
    • (1998) J. Appl. Physiol. , vol.85 , pp. 627-634
    • Richardson, R.S.1    Noyszewski, E.A.2    Leigh, J.S.3    Wagner, P.D.4
  • 81
    • 0035787309 scopus 로고    scopus 로고
    • Nuclear magnetic resonance studies of hepatic glucose metabolism in humans
    • Roden, M., Petersen, K. F., and Shulman, G. I. (2001). Nuclear magnetic resonance studies of hepatic glucose metabolism in humans. Recent Prog. Horm. Res. 56, 219-237. doi: 10.1210/rp.56.1.219
    • (2001) Recent Prog. Horm. Res. , vol.56 , pp. 219-237
    • Roden, M.1    Petersen, K.F.2    Shulman, G.I.3
  • 82
    • 0025286025 scopus 로고
    • Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles
    • Roth, D. A., and Brooks, G. A. (1990a). Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles. Arch. Biochem. Biophys. 279, 386-394. doi: 10.1016/0003-9861(90)90506-T
    • (1990) Arch. Biochem. Biophys. , vol.279 , pp. 386-394
    • Roth, D.A.1    Brooks, G.A.2
  • 83
    • 0025362226 scopus 로고
    • Lactate transport is mediated by a membrane-bound carrier in rat skeletal muscle sarcolemmal vesicles
    • Roth, D. A., and Brooks, G. A. (1990b). Lactate transport is mediated by a membrane-bound carrier in rat skeletal muscle sarcolemmal vesicles. Arch. Biochem. Biophys. 279, 377-385. doi: 10.1016/0003-9861(90)90505-S
    • (1990) Arch. Biochem. Biophys. , vol.279 , pp. 377-385
    • Roth, D.A.1    Brooks, G.A.2
  • 84
    • 78049233321 scopus 로고    scopus 로고
    • Pyruvate-enriched cardioplegia suppresses cardiopulmonary bypass-induced myocardial inflammation
    • Ryou, M. G., Flaherty, D. C., Hoxha, B., Gurji, H., Sun, J., Hodge, L. M., et al. (2010). Pyruvate-enriched cardioplegia suppresses cardiopulmonary bypass-induced myocardial inflammation. Ann. Thorac. Surg. 90, 1529-1535. doi: 10.1016/j.athoracsur.2010.06.010
    • (2010) Ann. Thorac. Surg. , vol.90 , pp. 1529-1535
    • Ryou, M.G.1    Flaherty, D.C.2    Hoxha, B.3    Gurji, H.4    Sun, J.5    Hodge, L.M.6
  • 85
    • 70350464508 scopus 로고    scopus 로고
    • Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass
    • Ryou, M. G., Flaherty, D. C., Hoxha, B., Sun, J., Gurji, H., Rodriguez, S., et al. (2009). Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass. Am. J. Physiol. Heart Circ. Physiol. 297, H1914-H1922. doi: 10.1152/ajpheart.01213.2008
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.297 , pp. H1914-H1922
    • Ryou, M.G.1    Flaherty, D.C.2    Hoxha, B.3    Sun, J.4    Gurji, H.5    Rodriguez, S.6
  • 86
    • 84862791983 scopus 로고    scopus 로고
    • Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway
    • Ryou, M. G., Liu, R., Ren, M., Sun, J., Mallet, R. T., and Yang, S. H. (2012). Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway. Stroke 43, 1101-1107. doi: 10.1161/STROKEAHA.111.620088
    • (2012) Stroke , vol.43 , pp. 1101-1107
    • Ryou, M.G.1    Liu, R.2    Ren, M.3    Sun, J.4    Mallet, R.T.5    Yang, S.H.6
  • 87
    • 33646764150 scopus 로고
    • Human cerebral lactate and pyruvate extraction. I. Control subjects
    • Scheinberg, P., Bourne, B., and Reinmuth, O. M. (1965). Human cerebral lactate and pyruvate extraction. I. Control subjects. Arch. Neurol. 12, 246-250. doi: 10.1001/archneur.1965.00460270022003
    • (1965) Arch. Neurol. , vol.12 , pp. 246-250
    • Scheinberg, P.1    Bourne, B.2    Reinmuth, O.M.3
  • 88
    • 0000879825 scopus 로고
    • The cerebral blood flow in male subjects as measured by the nitrous oxide technique normal values for blood flow, oxygen utilization, glucose utilization, and peripheral resistance, with observations on the effect of tilting and anxiety
    • Scheinberg, P., and Stead, E. A. (1949). The cerebral blood flow in male subjects as measured by the nitrous oxide technique. normal values for blood flow, oxygen utilization, glucose utilization, and peripheral resistance, with observations on the effect of tilting and anxiety. J. Clin. Invest. 28(5 Pt 2): 1163-1171. doi: 10.1172/JCI102150
    • (1949) J. Clin. Invest , vol.28 , Issue.5 , pp. 1163-1171
    • Scheinberg, P.1    Stead, E.A.2
  • 90
    • 29144469081 scopus 로고    scopus 로고
    • Lactate: the ultimate cerebral oxidative energy substrate?
    • Schurr, A. (2006). Lactate: the ultimate cerebral oxidative energy substrate? J. Cereb. Blood Flow Metab. 26, 142-152. doi: 10.1038/sj.jcbfm.9600174
    • (2006) J. Cereb. Blood Flow Metab. , vol.26 , pp. 142-152
    • Schurr, A.1
  • 91
    • 44449120436 scopus 로고    scopus 로고
    • Lactate: a major and crucial player in normal function of both muscle and brain
    • Schurr, A. (2008). Lactate: a major and crucial player in normal function of both muscle and brain. J. Physiol. 586(Pt 11): 2665-2666. doi: 10.1113/jphysiol.2008.155416
    • (2008) J. Physiol , vol.586 , pp. 2665-2666
    • Schurr, A.1
  • 92
    • 84910090293 scopus 로고    scopus 로고
    • Cerebral glycolysis: a century of persistent misunderstanding and misconception
    • Schurr, A. (2014). Cerebral glycolysis: a century of persistent misunderstanding and misconception. Front. Neurosci. 8:360. doi: 10.3389/fnins.2014.00360
    • (2014) Front. Neurosci , vol.8 , pp. 360
    • Schurr, A.1
  • 93
    • 84865959403 scopus 로고    scopus 로고
    • Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress
    • Schurr, A., and Gozal, E. (2011). Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress. Front. Pharmacol. 2:96. doi: 10.3389/fphar.2011.00096
    • (2011) Front. Pharmacol , vol.2 , pp. 96
    • Schurr, A.1    Gozal, E.2
  • 94
    • 34347212817 scopus 로고    scopus 로고
    • Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study
    • Schurr, A., and Payne, R. S. (2007). Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. Neuroscience 147, 613-619. doi: 10.1016/j.neuroscience.2007.05.002
    • (2007) Neuroscience , vol.147 , pp. 613-619
    • Schurr, A.1    Payne, R.S.2
  • 95
    • 0000221213 scopus 로고
    • Stress and the general adaptation syndrome
    • Selye, H. (1950). Stress and the general adaptation syndrome. Br. Med. J. 1, 1383-1392. doi: 10.1136/bmj.1.4667.1383
    • (1950) Br. Med. J. , vol.1 , pp. 1383-1392
    • Selye, H.1
  • 96
    • 0008689864 scopus 로고
    • Adaptive reaction to stress
    • Selye, H., and Fortier, C. (1950). Adaptive reaction to stress. Psychosom. Med. 12, 149-157. doi: 10.1097/00006842-195005000-00003
    • (1950) Psychosom. Med. , vol.12 , pp. 149-157
    • Selye, H.1    Fortier, C.2
  • 97
    • 36849086430 scopus 로고    scopus 로고
    • Pyruvate enhances neurological recovery following cardiopulmonary arrest and resuscitation
    • Sharma, A. B., Barlow, M. A., Yang, S. H., Simpkins, J. W., and Mallet, R. T. (2008). Pyruvate enhances neurological recovery following cardiopulmonary arrest and resuscitation. Resuscitation 76, 108-119. doi: 10.1016/j.resuscitation.2007.04.028
    • (2008) Resuscitation , vol.76 , pp. 108-119
    • Sharma, A.B.1    Barlow, M.A.2    Yang, S.H.3    Simpkins, J.W.4    Mallet, R.T.5
  • 98
    • 21544458780 scopus 로고    scopus 로고
    • Pyruvate improves cardiac electromechanical and metabolic recovery from cardiopulmonary arrest and resuscitation
    • Sharma, A. B., Knott, E. M., Bi, J., Martinez, R. R., Sun, J., and Mallet, R. T. (2005). Pyruvate improves cardiac electromechanical and metabolic recovery from cardiopulmonary arrest and resuscitation. Resuscitation 66, 71-81. doi: 10.1016/j.resuscitation.2004.12.016
    • (2005) Resuscitation , vol.66 , pp. 71-81
    • Sharma, A.B.1    Knott, E.M.2    Bi, J.3    Martinez, R.R.4    Sun, J.5    Mallet, R.T.6
  • 100
    • 0015551457 scopus 로고
    • Metabolism of ketone bodies by the brain
    • Sokoloff, L. (1973). Metabolism of ketone bodies by the brain. Annu. Rev. Med. 24, 271-280. doi: 10.1146/annurev.me.24.020173.001415
    • (1973) Annu. Rev. Med. , vol.24 , pp. 271-280
    • Sokoloff, L.1
  • 103
    • 84864285880 scopus 로고    scopus 로고
    • Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation
    • Stein, N. R., McArthur, D. L., Etchepare, M., and Vespa, P. M. (2012). Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation. Neurocrit. Care 17, 49-57. doi: 10.1007/s12028-012-9708-y
    • (2012) Neurocrit. Care , vol.17 , pp. 49-57
    • Stein, N.R.1    McArthur, D.L.2    Etchepare, M.3    Vespa, P.M.4
  • 104
    • 0035986009 scopus 로고    scopus 로고
    • Measurement of gluconeogenesis in exercising men by mass isotopomer distribution analysis
    • Trimmer, J. K., Schwarz, J. M., Casazza, G. A., Horning, M. A., Rodriguez, N., and Brooks, G. A. (2002). Measurement of gluconeogenesis in exercising men by mass isotopomer distribution analysis. J. Appl. Physiol. 93, 233-241. doi: 10.1152/japplphysiol.01050.2001
    • (2002) J. Appl. Physiol. , vol.93 , pp. 233-241
    • Trimmer, J.K.1    Schwarz, J.M.2    Casazza, G.A.3    Horning, M.A.4    Rodriguez, N.5    Brooks, G.A.6
  • 105
    • 33845539898 scopus 로고    scopus 로고
    • Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm
    • Van den Berghe, G., Wilmer, A., Milants, I., Wouters, P. J., Bouckaert, B., Bruyninckx, F., et al. (2006). Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes 55, 3151-3159. doi: 10.2337/db06-0855
    • (2006) Diabetes , vol.55 , pp. 3151-3159
    • Van den Berghe, G.1    Wilmer, A.2    Milants, I.3    Wouters, P.J.4    Bouckaert, B.5    Bruyninckx, F.6
  • 108
    • 84861496203 scopus 로고    scopus 로고
    • Tight glycemic control increases metabolic distress in traumatic brain injury: a randomized controlled within-subjects trial
    • Vespa, P., McArthur, D. L., Stein, N., Huang, S. C., Shao, W., Filippou, M., et al. (2012). Tight glycemic control increases metabolic distress in traumatic brain injury: a randomized controlled within-subjects trial. Crit. Care Med. 40, 1923-1929. doi: 10.1097/CCM.0b013e31824e0fcc
    • (2012) Crit. Care Med. , vol.40 , pp. 1923-1929
    • Vespa, P.1    McArthur, D.L.2    Stein, N.3    Huang, S.C.4    Shao, W.5    Filippou, M.6
  • 109
    • 84875110676 scopus 로고    scopus 로고
    • Nutritional support for patients sustaining traumatic brain injury: a systematic review and meta-analysis of prospective studies
    • Wang, X., Dong, Y., Han, X., Qi, X. Q., Huang, C. G., and Hou, L. J. (2013). Nutritional support for patients sustaining traumatic brain injury: a systematic review and meta-analysis of prospective studies. PLoS ONE 8:e58838. doi: 10.1371/journal.pone.0058838
    • (2013) PLoS ONE , vol.8
    • Wang, X.1    Dong, Y.2    Han, X.3    Qi, X.Q.4    Huang, C.G.5    Hou, L.J.6
  • 110
    • 79956330533 scopus 로고    scopus 로고
    • In vivo evidence for lactate as a neuronal energy source
    • Wyss, M. T., Jolivet, R., Buck, A., Magistretti, P. J., and Weber, B. (2011). In vivo evidence for lactate as a neuronal energy source. J. Neurosci. 31, 7477-7485. doi: 10.1523/JNEUROSCI.0415-11.2011
    • (2011) J. Neurosci. , vol.31 , pp. 7477-7485
    • Wyss, M.T.1    Jolivet, R.2    Buck, A.3    Magistretti, P.J.4    Weber, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.