메뉴 건너뛰기




Volumn 18, Issue 1, 2014, Pages

Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: A review

Author keywords

[No Author keywords available]

Indexed keywords

EXOU PROTEIN; PHOSPHOLIPASE A2; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BACTERIAL TOXIN; PSEUDOMONAS EXOPROTEIN A PROTEIN, PSEUDOMONAS AERUGINOSA;

EID: 84924258338     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-014-0668-9     Document Type: Review
Times cited : (99)

References (100)
  • 1
    • 84888269806 scopus 로고    scopus 로고
    • A comparison of microbiology and demographics among patients with healthcare-associated, hospital-acquired, and ventilator-associated pneumonia: a retrospective analysis of 1184 patients from a large, international study
    • Quartin AA, Scerpella EG, Puttagunta S, Kett DH: A comparison of microbiology and demographics among patients with healthcare-associated, hospital-acquired, and ventilator-associated pneumonia: a retrospective analysis of 1184 patients from a large, international study. BMC Infect Dis 2013, 13:561.
    • (2013) BMC Infect Dis , vol.13 , pp. 561
    • Quartin, A.A.1    Scerpella, E.G.2    Puttagunta, S.3    Kett, D.H.4
  • 2
    • 84878228828 scopus 로고    scopus 로고
    • Management and prevention of ventilator-associated pneumonia caused by multidrug-resistant pathogens
    • Grgurich PE, Hudcova J, Lei Y, Sarwar A, Craven DE: Management and prevention of ventilator-associated pneumonia caused by multidrug-resistant pathogens. Expert Rev Respir Med 2012, 6:533-555.
    • (2012) Expert Rev Respir Med , vol.6 , pp. 533-555
    • Grgurich, P.E.1    Hudcova, J.2    Lei, Y.3    Sarwar, A.4    Craven, D.E.5
  • 3
    • 84878103683 scopus 로고    scopus 로고
    • Hospital-acquired pneumonia and ventilator-associated pneumonia: recent advances in epidemiology and management
    • Barbier F, Andremont A, Wolff M, Bouadma L: Hospital-acquired pneumonia and ventilator-associated pneumonia: recent advances in epidemiology and management. Curr Opinion Pulm Med 2013, 19:216-228.
    • (2013) Curr Opinion Pulm Med , vol.19 , pp. 216-228
    • Barbier, F.1    Andremont, A.2    Wolff, M.3    Bouadma, L.4
  • 4
    • 84862546415 scopus 로고    scopus 로고
    • Management of ventilator-associated pneumonia: epidemiology, diagnosis and antimicrobial therapy
    • Bassetti M, Taramasso L, Giacobbe DR, Pelosi P: Management of ventilator-associated pneumonia: epidemiology, diagnosis and antimicrobial therapy. Expert Rev Anti-infective Ther 2012, 10:585-596.
    • (2012) Expert Rev Anti-infective Ther , vol.10 , pp. 585-596
    • Bassetti, M.1    Taramasso, L.2    Giacobbe, D.R.3    Pelosi, P.4
  • 5
    • 84859171064 scopus 로고    scopus 로고
    • Ventilator-associated pneumonia caused by ESKAPE organisms: cause, clinical features, and management
    • Sandiumenge A, Rello J: Ventilator-associated pneumonia caused by ESKAPE organisms: cause, clinical features, and management. Curr Opinion Pulm Med 2012, 18:187-193.
    • (2012) Curr Opinion Pulm Med , vol.18 , pp. 187-193
    • Sandiumenge, A.1    Rello, J.2
  • 6
    • 84979197686 scopus 로고    scopus 로고
    • The molecular mechanism of acute lung injury caused by Pseudomonas aeruginosa: from bacterial pathogenesis to host response
    • Sawa T: The molecular mechanism of acute lung injury caused by Pseudomonas aeruginosa: from bacterial pathogenesis to host response. J Intensive Care 2014, 2:10.
    • (2014) J Intensive Care , vol.2 , pp. 10
    • Sawa, T.1
  • 7
    • 59849110833 scopus 로고    scopus 로고
    • Role of Pseudomonas aeruginosa type III effectors in disease
    • Engel J, Balachandran P: Role of Pseudomonas aeruginosa type III effectors in disease. Curr Opinion Microbiol 2009, 12:61-66.
    • (2009) Curr Opinion Microbiol , vol.12 , pp. 61-66
    • Engel, J.1    Balachandran, P.2
  • 8
    • 69249157248 scopus 로고    scopus 로고
    • The type III secretion system of Pseudomonas aeruginosa: infection by injection
    • Hauser AR: The type III secretion system of Pseudomonas aeruginosa: infection by injection. Nature Rev Microbiol 2009, 7:654-665.
    • (2009) Nature Rev Microbiol , vol.7 , pp. 654-665
    • Hauser, A.R.1
  • 11
    • 84891504003 scopus 로고    scopus 로고
    • Risk of developing pneumonia is enhanced by the combined traits of fluoroquinolone resistance and type III secretion virulence in respiratory isolates of Pseudomonas aeruginosa
    • Sullivan E, Bensman J, Lou M, Agnello M, Shriner K, Wong-Beringer A: Risk of developing pneumonia is enhanced by the combined traits of fluoroquinolone resistance and type III secretion virulence in respiratory isolates of Pseudomonas aeruginosa . Crit Care Med 2014, 42:48-56.
    • (2014) Crit Care Med , vol.42 , pp. 48-56
    • Sullivan, E.1    Bensman, J.2    Lou, M.3    Agnello, M.4    Shriner, K.5    Wong-Beringer, A.6
  • 12
    • 40549116990 scopus 로고    scopus 로고
    • Comparison of type III secretion system virulence among fluoroquinolone-susceptible and -resistant clinical isolates of Pseudomonas aeruginosa
    • Wong-Beringer A, Wiener-Kronish J, Lynch S, Flanagan J: Comparison of type III secretion system virulence among fluoroquinolone-susceptible and -resistant clinical isolates of Pseudomonas aeruginosa . Clin Microbiol Infect 2008, 14:330-336.
    • (2008) Clin Microbiol Infect , vol.14 , pp. 330-336
    • Wong-Beringer, A.1    Wiener-Kronish, J.2    Lynch, S.3    Flanagan, J.4
  • 14
    • 0028050672 scopus 로고
    • Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury
    • Kudoh I, Wiener-Kronish JP, Hashimoto S, Pittet JF, Frank D: Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury. Am J Physiol 1994, 267:L551-L556.
    • (1994) Am J Physiol , vol.267 , pp. L551-L556
    • Kudoh, I.1    Wiener-Kronish, J.P.2    Hashimoto, S.3    Pittet, J.F.4    Frank, D.5
  • 16
    • 0021906035 scopus 로고
    • Contribution of exoenzyme S to the virulence of Pseudomonas aeruginosa
    • Nicas TI, Iglewski BH: Contribution of exoenzyme S to the virulence of Pseudomonas aeruginosa . Antibiot Chemother 1985, 36:40-48.
    • (1985) Antibiot Chemother , vol.36 , pp. 40-48
    • Nicas, T.I.1    Iglewski, B.H.2
  • 17
    • 0021809838 scopus 로고
    • The contribution of exoproducts to virulence of Pseudomonas aeruginosa
    • Nicas TI, Iglewski BH: The contribution of exoproducts to virulence of Pseudomonas aeruginosa . Can J Microbiol 1985, 31:387-392.
    • (1985) Can J Microbiol , vol.31 , pp. 387-392
    • Nicas, T.I.1    Iglewski, B.H.2
  • 19
    • 0029801248 scopus 로고    scopus 로고
    • Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway
    • Yahr TL, Goranson J, Frank DW: Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway. Mol Microbiol 1996, 22:991-1003.
    • (1996) Mol Microbiol , vol.22 , pp. 991-1003
    • Yahr, T.L.1    Goranson, J.2    Frank, D.W.3
  • 20
    • 0031864184 scopus 로고    scopus 로고
    • Type III protein secretion systems in bacterial pathogens of animals and plants
    • Hueck CJ: Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol Mol Biol Rev 1998, 62:379-433.
    • (1998) Microbiol Mol Biol Rev , vol.62 , pp. 379-433
    • Hueck, C.J.1
  • 21
    • 0033591446 scopus 로고    scopus 로고
    • Type III secretion machines: bacterial devices for protein delivery into host cells
    • Galan JE, Collmer A: Type III secretion machines: bacterial devices for protein delivery into host cells. Science 1999, 284:1322-1328.
    • (1999) Science , vol.284 , pp. 1322-1328
    • Galan, J.E.1    Collmer, A.2
  • 22
    • 0030998981 scopus 로고    scopus 로고
    • Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells?
    • Lee CA: Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells? Trends Microbiol 1997, 5:148-156.
    • (1997) Trends Microbiol , vol.5 , pp. 148-156
    • Lee, C.A.1
  • 23
    • 0030726075 scopus 로고    scopus 로고
    • The exoenzyme S regulon of Pseudomonas aeruginosa
    • Frank DW: The exoenzyme S regulon of Pseudomonas aeruginosa . Mol Microbiol 1997, 26:621-629.
    • (1997) Mol Microbiol , vol.26 , pp. 621-629
    • Frank, D.W.1
  • 27
    • 0030606233 scopus 로고    scopus 로고
    • Pathogenicity islands: bacterial evolution in quantum leaps
    • Groisman EA, Ochman H: Pathogenicity islands: bacterial evolution in quantum leaps. Cell 1996, 87:791-794.
    • (1996) Cell , vol.87 , pp. 791-794
    • Groisman, E.A.1    Ochman, H.2
  • 28
    • 0029162189 scopus 로고
    • Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon
    • Hovey AK, Frank DW: Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol 1995, 177:4427-4436.
    • (1995) J Bacteriol , vol.177 , pp. 4427-4436
    • Hovey, A.K.1    Frank, D.W.2
  • 29
    • 0030044151 scopus 로고    scopus 로고
    • Genetic analysis of exoenzyme S expression by Pseudomonas aeruginosa
    • Goranson J, Frank DW: Genetic analysis of exoenzyme S expression by Pseudomonas aeruginosa . FEMS Microbiol Lett 1996, 135:149-155.
    • (1996) FEMS Microbiol Lett , vol.135 , pp. 149-155
    • Goranson, J.1    Frank, D.W.2
  • 31
    • 13244295376 scopus 로고    scopus 로고
    • Characterization of phospholipase activity of the Pseudomonas aeruginosa type III cytotoxin, ExoU
    • Sato H, Feix JB, Hillard CJ, Frank DW: Characterization of phospholipase activity of the Pseudomonas aeruginosa type III cytotoxin, ExoU. J Bacteriol 2005, 187:1192-1195.
    • (2005) J Bacteriol , vol.187 , pp. 1192-1195
    • Sato, H.1    Feix, J.B.2    Hillard, C.J.3    Frank, D.W.4
  • 32
    • 0000236933 scopus 로고
    • Lipid acyl hydrolase of patatin
    • Racusen D: Lipid acyl hydrolase of patatin. Can J Bot 1984, 62:1640.
    • (1984) Can J Bot , vol.62 , pp. 1640
    • Racusen, D.1
  • 33
    • 0024287753 scopus 로고
    • Characterization of the lipid acyl hydrolase activity of the major potato (Solanum tuberosum) tuber protein, patatin, by cloning and abundant expression in a baculovirus vector
    • Andrews DL, Beames B, Summers MD, Park WD: Characterization of the lipid acyl hydrolase activity of the major potato ( Solanum tuberosum ) tuber protein, patatin, by cloning and abundant expression in a baculovirus vector. Biochem J 1988, 252:199-206.
    • (1988) Biochem J , vol.252 , pp. 199-206
    • Andrews, D.L.1    Beames, B.2    Summers, M.D.3    Park, W.D.4
  • 35
    • 0034787011 scopus 로고    scopus 로고
    • Cloning, expression, purification and characterization of patatin, a novel phospholipase A
    • Hirschberg HJ, Simons JW, Dekker N, Egmond MR: Cloning, expression, purification and characterization of patatin, a novel phospholipase A. Eur J Biochem 2001, 268:5037-5044.
    • (2001) Eur J Biochem , vol.268 , pp. 5037-5044
    • Hirschberg, H.J.1    Simons, J.W.2    Dekker, N.3    Egmond, M.R.4
  • 39
    • 84924241262 scopus 로고    scopus 로고
    • Multiple Sequence Alignment by CLUSTALW [ http://www.genome.jp/tools/clustalw/ ]
  • 41
    • 1642365547 scopus 로고    scopus 로고
    • Patatin-like proteins: a new family of lipolytic enzymes present in bacteria?
    • Banerji S, Flieger A: Patatin-like proteins: a new family of lipolytic enzymes present in bacteria? Microbiol 2004, 150:522-525.
    • (2004) Microbiol , vol.150 , pp. 522-525
    • Banerji, S.1    Flieger, A.2
  • 42
    • 43049144298 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa utilises its type III secretion system to kill the free-living amoeba Acanthamoeba castellanii
    • Abd H, Wretlind B, Saeed A, Idsund E, Hultenby K, Sandstrom G: Pseudomonas aeruginosa utilises its type III secretion system to kill the free-living amoeba Acanthamoeba castellanii . J Eukaryotic Microbiol 2008, 55:235-243.
    • (2008) J Eukaryotic Microbiol , vol.55 , pp. 235-243
    • Abd, H.1    Wretlind, B.2    Saeed, A.3    Idsund, E.4    Hultenby, K.5    Sandstrom, G.6
  • 44
    • 0037634093 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa ExoU, a toxin transported by the type III secretion system, kills Saccharomyces cerevisiae
    • Rabin SD, Hauser AR: Pseudomonas aeruginosa ExoU, a toxin transported by the type III secretion system, kills Saccharomyces cerevisiae . Infect Immun 2003, 71:4144-4150.
    • (2003) Infect Immun , vol.71 , pp. 4144-4150
    • Rabin, S.D.1    Hauser, A.R.2
  • 45
    • 0032879168 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells
    • Hauser AR, Engel JN: Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells. Infect Immun 1999, 67:5530-5537.
    • (1999) Infect Immun , vol.67 , pp. 5530-5537
    • Hauser, A.R.1    Engel, J.N.2
  • 47
    • 77950271943 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa cytotoxin ExoU is injected into phagocytic cells during acute pneumonia
    • Diaz MH, Hauser AR: Pseudomonas aeruginosa cytotoxin ExoU is injected into phagocytic cells during acute pneumonia. Infect Immun 2010, 78:1447-1456.
    • (2010) Infect Immun , vol.78 , pp. 1447-1456
    • Diaz, M.H.1    Hauser, A.R.2
  • 48
    • 84880050608 scopus 로고    scopus 로고
    • Type III secretion of ExoU is critical during early Pseudomonas aeruginosa pneumonia
    • e00032-00013
    • Howell HA, Logan LK, Hauser AR: Type III secretion of ExoU is critical during early Pseudomonas aeruginosa pneumonia. MBio 2013, 4:e00032-00013.
    • (2013) MBio , vol.4
    • Howell, H.A.1    Logan, L.K.2    Hauser, A.R.3
  • 49
    • 0033916705 scopus 로고    scopus 로고
    • Acquisition of expression of the Pseudomonas aeruginosa ExoU cytotoxin leads to increased bacterial virulence in a murine model of acute pneumonia and systemic spread
    • Allewelt M, Coleman FT, Grout M, Priebe GP, Pier GB: Acquisition of expression of the Pseudomonas aeruginosa ExoU cytotoxin leads to increased bacterial virulence in a murine model of acute pneumonia and systemic spread. Infect Immun 2000, 68:3998-4004.
    • (2000) Infect Immun , vol.68 , pp. 3998-4004
    • Allewelt, M.1    Coleman, F.T.2    Grout, M.3    Priebe, G.P.4    Pier, G.B.5
  • 50
    • 9244236027 scopus 로고    scopus 로고
    • Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung
    • Shaver CM, Hauser AR: Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung. Infect Immun 2004, 72:6969-6977.
    • (2004) Infect Immun , vol.72 , pp. 6969-6977
    • Shaver, C.M.1    Hauser, A.R.2
  • 53
    • 33845578738 scopus 로고    scopus 로고
    • Proapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesis
    • Henderson FC, Miakotina OL, Mallampalli RK: Proapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesis. J Lipid Res 2006, 47:2314-2324.
    • (2006) J Lipid Res , vol.47 , pp. 2314-2324
    • Henderson, F.C.1    Miakotina, O.L.2    Mallampalli, R.K.3
  • 56
    • 77149151879 scopus 로고    scopus 로고
    • ExoU-induced vascular hyperpermeability and platelet activation in the course of experimental Pseudomonas aeruginosa pneumosepsis
    • Machado GB, de Assis MC, Leao R, Saliba AM, Silva MC, Suassuna JH, de Oliveira AV, Plotkowski MC: ExoU-induced vascular hyperpermeability and platelet activation in the course of experimental Pseudomonas aeruginosa pneumosepsis. Shock 2010, 33:315-321.
    • (2010) Shock , vol.33 , pp. 315-321
    • Machado, G.B.1    Assis, M.C.2    Leao, R.3    Saliba, A.M.4    Silva, M.C.5    Suassuna, J.H.6    Oliveira, A.V.7    Plotkowski, M.C.8
  • 57
    • 0027461546 scopus 로고
    • The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family
    • Fu H, Coburn J, Collier RJ: The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family. Proc Nat Acad Sci U S A 1993, 90:2320-2324.
    • (1993) Proc Nat Acad Sci U S A , vol.90 , pp. 2320-2324
    • Fu, H.1    Coburn, J.2    Collier, R.J.3
  • 58
    • 0025809268 scopus 로고
    • Pseudomonas aeruginosa exoenzyme S requires a eukaryotic protein for ADP-ribosyltransferase activity
    • Coburn J, Kane AV, Feig L, Gill DM: Pseudomonas aeruginosa exoenzyme S requires a eukaryotic protein for ADP-ribosyltransferase activity. J Biol Chem 1991, 266:6438-6446.
    • (1991) J Biol Chem , vol.266 , pp. 6438-6446
    • Coburn, J.1    Kane, A.V.2    Feig, L.3    Gill, D.M.4
  • 60
    • 11144265658 scopus 로고    scopus 로고
    • Functional regions of the Pseudomonas aeruginosa cytotoxin ExoU
    • Rabin SD, Hauser AR: Functional regions of the Pseudomonas aeruginosa cytotoxin ExoU. Infect Immun 2005, 73:573-582.
    • (2005) Infect Immun , vol.73 , pp. 573-582
    • Rabin, S.D.1    Hauser, A.R.2
  • 61
    • 33646374906 scopus 로고    scopus 로고
    • A C-terminal domain targets the Pseudomonas aeruginosa cytotoxin ExoU to the plasma membrane of host cells
    • Rabin SD, Veesenmeyer JL, Bieging KT, Hauser AR: A C-terminal domain targets the Pseudomonas aeruginosa cytotoxin ExoU to the plasma membrane of host cells. Infect Immun 2006, 74:2552-2561.
    • (2006) Infect Immun , vol.74 , pp. 2552-2561
    • Rabin, S.D.1    Veesenmeyer, J.L.2    Bieging, K.T.3    Hauser, A.R.4
  • 62
    • 77955302592 scopus 로고    scopus 로고
    • Role of the membrane localization domain of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicity
    • Veesenmeyer JL, Howell H, Halavaty AS, Ahrens S, Anderson WF, Hauser AR: Role of the membrane localization domain of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicity. Infect Immun 2010, 78:3346-3357.
    • (2010) Infect Immun , vol.78 , pp. 3346-3357
    • Veesenmeyer, J.L.1    Howell, H.2    Halavaty, A.S.3    Ahrens, S.4    Anderson, W.F.5    Hauser, A.R.6
  • 63
    • 33748672064 scopus 로고    scopus 로고
    • Identification of superoxide dismutase as a cofactor for the pseudomonas type III toxin, ExoU
    • Sato H, Feix JB, Frank DW: Identification of superoxide dismutase as a cofactor for the pseudomonas type III toxin, ExoU. Biochemistry 2006, 45:10368-10375.
    • (2006) Biochemistry , vol.45 , pp. 10368-10375
    • Sato, H.1    Feix, J.B.2    Frank, D.W.3
  • 64
    • 33745621121 scopus 로고    scopus 로고
    • Eukaryotic localization, activation and ubiquitinylation of a bacterial type III secreted toxin
    • Stirling FR, Cuzick A, Kelly SM, Oxley D, Evans TJ: Eukaryotic localization, activation and ubiquitinylation of a bacterial type III secreted toxin. Cell Microbiol 2006, 8:1294-1309.
    • (2006) Cell Microbiol , vol.8 , pp. 1294-1309
    • Stirling, F.R.1    Cuzick, A.2    Kelly, S.M.3    Oxley, D.4    Evans, T.J.5
  • 65
    • 79953903080 scopus 로고    scopus 로고
    • Induced conformational changes in the activation of the Pseudomonas aeruginosa type III toxin, ExoU
    • Benson MA, Komas SM, Schmalzer KM, Casey MS, Frank DW, Feix JB: Induced conformational changes in the activation of the Pseudomonas aeruginosa type III toxin, ExoU. Biophys J 2011, 100:1335-1343.
    • (2011) Biophys J , vol.100 , pp. 1335-1343
    • Benson, M.A.1    Komas, S.M.2    Schmalzer, K.M.3    Casey, M.S.4    Frank, D.W.5    Feix, J.B.6
  • 70
    • 84880654391 scopus 로고    scopus 로고
    • Phosphatidylinositol 4,5-bisphosphate is a novel coactivator of the Pseudomonas aeruginosa cytotoxin ExoU
    • Tyson GH, Hauser AR: Phosphatidylinositol 4,5-bisphosphate is a novel coactivator of the Pseudomonas aeruginosa cytotoxin ExoU. Infect Immun 2013, 81:2873-2881.
    • (2013) Infect Immun , vol.81 , pp. 2873-2881
    • Tyson, G.H.1    Hauser, A.R.2
  • 71
    • 80052551902 scopus 로고    scopus 로고
    • 2 activities and can function in the absence of any eukaryotic cofactors in vitro
    • 2 activities and can function in the absence of any eukaryotic cofactors in vitro. J Bacteriol 2011, 193:4634-4642.
    • (2011) J Bacteriol , vol.193 , pp. 4634-4642
    • Housley, N.A.1    Winkler, H.H.2    Audia, J.P.3
  • 73
    • 0034769748 scopus 로고    scopus 로고
    • Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa
    • Feltman H, Schulert G, Khan S, Jain M, Peterson L, Hauser AR: Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa . Microbiol 2001, 147:2659-2669.
    • (2001) Microbiol , vol.147 , pp. 2659-2669
    • Feltman, H.1    Schulert, G.2    Khan, S.3    Jain, M.4    Peterson, L.5    Hauser, A.R.6
  • 74
    • 0346256754 scopus 로고    scopus 로고
    • Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia
    • Schulert GS, Feltman H, Rabin SD, Martin CG, Battle SE, Rello J, Hauser AR: Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia. J Infect Dis 2003, 188:1695-1706.
    • (2003) J Infect Dis , vol.188 , pp. 1695-1706
    • Schulert, G.S.1    Feltman, H.2    Rabin, S.D.3    Martin, C.G.4    Battle, S.E.5    Rello, J.6    Hauser, A.R.7
  • 75
    • 34249664460 scopus 로고    scopus 로고
    • A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates
    • Wareham DW, Curtis MA: A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates. Int J Medl Microbiol 2007, 297:227-234.
    • (2007) Int J Medl Microbiol , vol.297 , pp. 227-234
    • Wareham, D.W.1    Curtis, M.A.2
  • 76
    • 77955291363 scopus 로고    scopus 로고
    • Virulence gene distribution in clinical, nosocomial and environmental isolates of Pseudomonas aeruginosa
    • Bradbury RS, Roddam LF, Merritt A, Reid DW, Champion AC: Virulence gene distribution in clinical, nosocomial and environmental isolates of Pseudomonas aeruginosa . J Med Microbiol 2010, 59:881-890.
    • (2010) J Med Microbiol , vol.59 , pp. 881-890
    • Bradbury, R.S.1    Roddam, L.F.2    Merritt, A.3    Reid, D.W.4    Champion, A.C.5
  • 79
    • 84874320329 scopus 로고    scopus 로고
    • Type 3 secretion system effector genotype and secretion phenotype of longitudinally collected Pseudomonas aeruginosa isolates from young children diagnosed with cystic fibrosis following newborn screening
    • Hu H, Harmer C, Anuj S, Wainwright CE, Manos J, Cheney J, Harbour C, Zablotska I, Turnbull L, Whitchurch CB, Grimwood K, Rose B, ACFBAL study investigators: Type 3 secretion system effector genotype and secretion phenotype of longitudinally collected Pseudomonas aeruginosa isolates from young children diagnosed with cystic fibrosis following newborn screening. Clin Microbiol Infect 2013, 19:266-272.
    • (2013) Clin Microbiol Infect , vol.19 , pp. 266-272
  • 80
    • 0036191393 scopus 로고    scopus 로고
    • Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa
    • Hauser AR, Cobb E, Bodi M, Mariscal D, Valles J, Engel JN, Rello J: Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa . Crit Care Med 2002, 30:521-528.
    • (2002) Crit Care Med , vol.30 , pp. 521-528
    • Hauser, A.R.1    Cobb, E.2    Bodi, M.3    Mariscal, D.4    Valles, J.5    Engel, J.N.6    Rello, J.7
  • 81
    • 59349109012 scopus 로고    scopus 로고
    • Prevalence of type III secretion protein exoenzymes and antimicrobial susceptibility patterns from bloodstream isolates of patients with Pseudomonas aeruginosa bacteremia
    • Garey KW, Vo QP, Larocco MT, Gentry LO, Tam VH: Prevalence of type III secretion protein exoenzymes and antimicrobial susceptibility patterns from bloodstream isolates of patients with Pseudomonas aeruginosa bacteremia. J Chemother 2008, 20:714-720.
    • (2008) J Chemother , vol.20 , pp. 714-720
    • Garey, K.W.1    Vo, Q.P.2    Larocco, M.T.3    Gentry, L.O.4    Tam, V.H.5
  • 82
    • 84864647674 scopus 로고    scopus 로고
    • Differentiation in quinolone resistance by virulence genotype in Pseudomonas aeruginosa
    • Agnello M, Wong-Beringer A: Differentiation in quinolone resistance by virulence genotype in Pseudomonas aeruginosa . PloS One 2012, 7:e42973.
    • (2012) PloS One , vol.7
    • Agnello, M.1    Wong-Beringer, A.2
  • 84
    • 84868208915 scopus 로고    scopus 로고
    • Evaluation of biofilm production and characterization of genes encoding type III secretion system among Pseudomonas aeruginosa isolated from burn patients
    • Jabalameli F, Mirsalehian A, Khoramian B, Aligholi M, Khoramrooz SS, Asadollahi P, Taherikalani M, Emaneini M: Evaluation of biofilm production and characterization of genes encoding type III secretion system among Pseudomonas aeruginosa isolated from burn patients. Burns 2012, 38:1192-1197.
    • (2012) Burns , vol.38 , pp. 1192-1197
    • Jabalameli, F.1    Mirsalehian, A.2    Khoramian, B.3    Aligholi, M.4    Khoramrooz, S.S.5    Asadollahi, P.6    Taherikalani, M.7    Emaneini, M.8
  • 85
    • 77954303046 scopus 로고    scopus 로고
    • Prevalence of virulence genes among Bulgarian nosocomial and cystic fibrosis isolates of Pseudomonas aeruginosa
    • Mitov I, Strateva T, Markova B: Prevalence of virulence genes among Bulgarian nosocomial and cystic fibrosis isolates of Pseudomonas aeruginosa . Brazilian J Microbiol 2010, 41:588-595.
    • (2010) Brazilian J Microbiol , vol.41 , pp. 588-595
    • Mitov, I.1    Strateva, T.2    Markova, B.3
  • 86
    • 79952425151 scopus 로고    scopus 로고
    • Detection of type III secretion system virulence and mutations in gyrA and parC genes among quinolone-resistant strains of Pseudomonas aeruginosa isolated from imported shrimp
    • Tran QT, Nawaz MS, Deck J, Foley S, Nguyen K, Cerniglia CE: Detection of type III secretion system virulence and mutations in gyrA and parC genes among quinolone-resistant strains of Pseudomonas aeruginosa isolated from imported shrimp. Foodborne Pathogens Dis 2011, 8:451-453.
    • (2011) Foodborne Pathogens Dis , vol.8 , pp. 451-453
    • Tran, Q.T.1    Nawaz, M.S.2    Deck, J.3    Foley, S.4    Nguyen, K.5    Cerniglia, C.E.6
  • 87
    • 84904421799 scopus 로고    scopus 로고
    • Correlation between virulence genotype and fluoroquinolone resistance in carbapenem-resistant Pseudomonas aeruginosa
    • Cho HH, Kwon KC, Kim S, Koo SH: Correlation between virulence genotype and fluoroquinolone resistance in carbapenem-resistant Pseudomonas aeruginosa . Ann Lab Med 2014, 34:286-292.
    • (2014) Ann Lab Med , vol.34 , pp. 286-292
    • Cho, H.H.1    Kwon, K.C.2    Kim, S.3    Koo, S.H.4
  • 88
    • 84899922148 scopus 로고    scopus 로고
    • V-antigen homologs in pathogenic gram-negative bacteria
    • Sawa T, Katoh H, Yasumoto H: V-antigen homologs in pathogenic gram-negative bacteria. Microbiol Immunol 2014, 58:267-285.
    • (2014) Microbiol Immunol , vol.58 , pp. 267-285
    • Sawa, T.1    Katoh, H.2    Yasumoto, H.3
  • 89
    • 0032907634 scopus 로고    scopus 로고
    • Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury
    • Sawa T, Yahr TL, Ohara M, Kurahashi K, Gropper MA, Wiener-Kronish JP, Frank DW: Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury. Nat Med 1999, 5:392-398.
    • (1999) Nat Med , vol.5 , pp. 392-398
    • Sawa, T.1    Yahr, T.L.2    Ohara, M.3    Kurahashi, K.4    Gropper, M.A.5    Wiener-Kronish, J.P.6    Frank, D.W.7
  • 90
    • 84900343586 scopus 로고    scopus 로고
    • Protective effect of DNA vaccine encoding pseudomonas exotoxin A and PcrV against acute pulmonary P. aeruginosa infection
    • Jiang M, Yao J, Feng G: Protective effect of DNA vaccine encoding pseudomonas exotoxin A and PcrV against acute pulmonary P. aeruginosa infection. PLoS One 2014, 9:e96609.
    • (2014) PLoS One , vol.9
    • Jiang, M.1    Yao, J.2    Feng, G.3
  • 96
    • 62449123361 scopus 로고    scopus 로고
    • An engineered human antibody Fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent anti-bacterial activity
    • Baer M, Sawa T, Flynn P, Luehrsen K, Martinez D, Wiener-Kronish JP, Yarranton G, Bebbington C: An engineered human antibody Fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent anti-bacterial activity. Infect Immun 2008, 77:1083-1090.
    • (2008) Infect Immun , vol.77 , pp. 1083-1090
    • Baer, M.1    Sawa, T.2    Flynn, P.3    Luehrsen, K.4    Martinez, D.5    Wiener-Kronish, J.P.6    Yarranton, G.7    Bebbington, C.8
  • 98
    • 84903381980 scopus 로고    scopus 로고
    • Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infection
    • Milla CE, Chmiel JF, Accurso FJ, Vandevanter DR, Konstan MW, Yarranton G, Geller DE, for the KB001 Study Group: Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infection. Pediatr Pulmonol 2014, 49:650-658.
    • (2014) Pediatr Pulmonol , vol.49 , pp. 650-658


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.