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Volumn 30, Issue 3, 2002, Pages 521-528

Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa

Author keywords

Bacterial infections; Bacterial toxins; Hospital mortality; Pneumonia; Pseudomonas aeruginosa; Treatment outcome

Indexed keywords

BACTERIAL TOXIN; PROTEIN;

EID: 0036191393     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200203000-00005     Document Type: Article
Times cited : (354)

References (68)
  • 1
    • 0345514343 scopus 로고    scopus 로고
    • National Nosocomial Infections Surveillance report, data summary from October 1986-April 1996, issued May 1996
    • (1996) Am J Infect Control , vol.24 , pp. 380-388
  • 2
    • 0027367592 scopus 로고
    • Impact of previous antimicrobial therapy on the etiology and outcome of ventilator-associated pneumonia
    • (1993) Chest , vol.104 , pp. 1230-1235
    • Rello, J.1    Ausina, V.2    Ricart, M.3
  • 6
    • 0031879743 scopus 로고    scopus 로고
    • Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative Gram-negative bacteria
    • (1998) Clin Infect Dis , vol.27
    • Hancock, R.E.1
  • 20
    • 0026017956 scopus 로고
    • Pseudomonas aeruginosa elastase and elastolysis revisited: Recent developments
    • (1991) Mol Microbiol , vol.5 , pp. 2315-2321
    • Galloway, D.R.1
  • 23
    • 0030045365 scopus 로고    scopus 로고
    • Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection
    • (1996) Infect Immun , vol.64 , pp. 37-43
    • Tang, H.B.1    DiMango, E.2    Bryan, R.3
  • 26
    • 0035153829 scopus 로고    scopus 로고
    • Genetic and biochemical analyses of a eukaryotic-like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection model
    • (2001) Mol Microbiol , vol.39 , pp. 291-303
    • Wilderman, P.J.1    Vasil, A.I.2    Johnson, Z.3
  • 28
  • 35
    • 0030922964 scopus 로고    scopus 로고
    • Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments
    • (1997) Mol Microbiol , vol.25 , pp. 1125-1139
    • Frithz-Lindsten, E.1    Du, Y.2    Rosqvist, R.3
  • 45
    • 0034444645 scopus 로고    scopus 로고
    • The arginine finger domain of ExoT contributes to actin cytoskeleton disruption and inhibition of internalization of Pseudomonas aeruginosa by epithelial cells and macrophages
    • (2000) Infect Immun , vol.68 , pp. 7100-7113
    • Garrity-Ryan, L.1    Kazmierczak, B.2    Kowal, R.3
  • 48
    • 0033031869 scopus 로고    scopus 로고
    • Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system
    • (1999) Infect Immun , vol.67 , pp. 3151-3154
    • Coburn, J.1    Frank, D.2
  • 49
    • 0032879168 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa induces type III secretion-mediated apoptosis of macrophages and epithelial cells
    • (1999) Infect Immun , vol.67 , pp. 5530-5537
    • Hauser, A.R.1    Engel, J.N.2
  • 51
    • 0033916705 scopus 로고    scopus 로고
    • Acquisition of expression of the Pseudomonas aeruginosa ExoU cytotoxin leads to increased bacterial virulence in a murine model of acute pneumonia and systemic spread
    • (2000) Infect Immun , vol.68 , pp. 3998-4004
    • Allewelt, M.1    Coleman, F.T.2    Grout, M.3
  • 56
    • 0021257575 scopus 로고
    • Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S
    • (1984) Infect Immun , vol.45 , pp. 470-474
    • Nicas, T.I.1    Iglewski, B.H.2
  • 58
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 63
    • 0025948303 scopus 로고
    • Cloning and sequence analysis of a trans-regulatory locus required for Exoenzyme S synthesis in Pseudomonas aeruginosa
    • (1991) J Bacteriol , vol.173 , pp. 6460-6468
    • Frank, D.1    Iglewski, B.H.2
  • 64
    • 0035173475 scopus 로고    scopus 로고
    • Expression of ExsA in trans confers type III secretion system-dependent cytotoxicity on noncytotoxic Pseudomonas aeruginosa cystic fibrosis isolates
    • (2001) Infect Immun , vol.69 , pp. 538-542
    • Dacheux, D.1    Attree, I.2    Toussaint, B.3
  • 65
    • 0032907634 scopus 로고    scopus 로고
    • Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury
    • (1999) Nat Med , vol.5 , pp. 392-398
    • Sawa, T.1    Yahr, T.2    Ohara, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.